Gene Details:

• MSU gene ID: LOC_Os06g50060
• RAPdb gene ID: Os06g0714600
• Gene Symbol: OsPRA2
• Genome: MSU7 ,  IRGSP-1.0
• Species: Oryza sativa

Functional Descriptions:

• Lamina inclination, coleoptile elongation, and root inhibition assays indicated that rice plants with suppressed expression of OsPRA2 were more sensitive to exogenously applied brassinolide than wild-type plants.
• Mechanistic study uncovered that OsPRA2 inhibited the dephosphorylation of, and thus inactivated the transcription factor BRASSINAZOLE-RESISTANT 1 (OsBZR1).
• More importantly, OsPRA2 was found to co-localize with and directly bind to rice BR receptor BRASSINOSTEROID-INSENSITIVE 1 (OsBRI1) on the plasma membrane.
• Together, these results revealed a possible working mechanism of OsPRA2 as a novel negative regulator on OsBRI1 and OsBZR1 in the BR signaling pathway in rice, and further extended the knowledge about the regulatory mechanism of rice BR signaling.
• OsPRA2 fine-tunes rice brassinosteroid receptor.
• Overexpression of OsGAP1 in Arabidopsis resulted in a phenotype mimic to BR-deficiency, implying that the GTPase activity of OsPRA2 is also involved in regulating BR signaling.

Function-related keywords:

• root ,  transcription-factor ,  BR ,  BR-signaling ,  lamina ,  plasma-membrane ,  brassinosteroid ,  Brassinosteroid

Literature:

• A Small G Protein as a Novel Component of the Rice Brassinosteroid Signal Transduction .  DOI:  10.1016/j.molp.2016.06.010 ;  PMID:  27375203
• OsPRA2 fine-tunes rice brassinosteroid receptor .  DOI:  10.1080/15592324.2016.1257455 ;  PMID:  28402719

Related News:

Gene Resources:

• NCBI ID:
• UniProt accessions:

Sequences: