Gene Details:

• Gene ID: Zm00001eb244650
• Gene Symbol: ZmRIBA1 o18
• Gene Name: opaque18
• Genome: Zm-B73-REFERENCE-NAM-5.0
• Species: Zea mays

Functional Descriptions:

• O18 encodes a rate-limiting bifunctional enzyme ZmRIBA1, targeted to plastid where to initiate riboflavin biosynthesis.
• Substantiate a key role of riboflavin in coordinating cellular energy and cell cycle to modulate maize endosperm development.
• Overexpression of o18 increases riboflavin production and confers osmotic tolerance.
• Here, we report a novel maize (Zea mays L.) opaque mutant o18, which displays an increase in lysine accumulation, but impaired endosperm filling and embryo development.
• Loss of function of o18 specifically disrupts respiratory complexes I and II, but also decreases SDH1 flavinylation, and in turn shifts the mitochondrial tricarboxylic acid (TCA) cycle to glycolysis.

Function-related keywords:

• development ,  tolerance ,  embryo ,  endosperm ,  cell-cycle ,  osmotic-tolerance ,  endosperm-development ,  plastid ,  embryo-development

Literature:

• Riboflavin integrates cellular energetics and cell cycle to regulate maize seed development.   DOI:  10.1111/pbi.13826 ;  PMID:  35426230

Related News:

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Gene Resources:

• NCBI ID: 100304324
• UniProt accessions: C0HET9

Sequences:

Source: Genetic information comes from the article