Gene Details:

Functional Descriptions:

  • RNA-sequencing coupled with gene expression assays revealed that both ZmARF3 and ZmARF30 directly bind the promoter of Polyamine Oxidase 1 (ZmPAO1) and activate its expression.
  • We uncovered a role of the Zma-miR167-ZmARF3/30 module for restricting MCMV infection by regulating ZmPAO1 expression, while MCMV employs p31 to counteract this defense.
  • Knockdown or inhibition of enzymatic activity of ZmPAO1 suppressed MCMV infection. Nevertheless.
  • Silencing of ZmPAO1 transcripts or inhibiting ZmPAO activity suppressed MCMV infection.
  • MCMV-encoded p31 protein directly targets and enhances ZmPAO1 enzyme activity.
  • ZmPAO1 plays an important role in tumor development during the maize-U.

Literature:

Gene Resources:

Sequences:

cDNA Sequence
  • >Zm00001eb413630_T002
    TGTATATATATGAGGGGTGAGAGGGGGGAGGGGCCTGGGGAGCAACACAAGCACTCCACACTGCTGTGCAGAACGAGAGCGTAACCATCAGTACTCAATAGTTAGAGCGACCAATAGATGAGTTCCTCCCCGTCCTTTGGTCTCCTGGCCTTAGCAGCAGTACTCCTAGCACTGAACTTAGCACAACATGGCTCCCTCGCCGCAACCGTCGGCCCCAGGGTCATCGTCGTCGGCGCCGGCATGTCTGGGATCTCGGCGGCGAAGAGGCTGTCGGAGGCCGGGATAACCGACCTGCTGATTCTGGAAGCGACGGACCACATCGGCGGGCGGATGCACAAGACGAACTTCGCCGGCATCAACGTCGAGTTAGGCGCCAACTGGGTGGAGGGCGTGAACGGCGGCAAGATGAACCCCATCTGGCCCATCGTCAACTCCACCCTCAAGCTCCGCAACTTCCGCTCCGACTTCGACTACCTCGCTCAGAACGTCTACAAGGAGGACGGTGGCGTCTACGATGAAGATTACGTCCAGAAGAGAATTGAACTGGCGGACAGCGTGGAAGAGATGGGGGAGAAGCTCTCTGCCACTTTGCACGCCAGTGGCAGAGACGACATGTCTATCCTTGCCATGCAGCGCCTCAACGAACAGTACGTGTGTCCTATATATACCTGCAGCTCCTCAACACATACATACATACATACATACAACAACAGCTGAATGCAATGCAATGCAATGGGCATGTGCATGCAGCCAGCCGAACGGGCCGGCGACGCCGGTGGACATGGTGGTGGACTACTACAAGTTCGACTACGAGTTCGCGGAGCCGCCGCGCGTGACCAGCCTGCAGAACACCGTGCCTCTCGCGACCTTCAGCGACTTCGGCGACGACGTCTACTTCGTCGCCGACCAGCGGGGCTACGAGGCCGTCGTCTACTACCTCGCCGGCCAGTACCTCAAGACCGACGATAAGTCTGGAAAGATCGTCGACCCGCGCCTGCAGCTCAACAAGGTGGTGCGAGAGATCAAGTATTCCCCGGGTGGCGTCACCGTCAAGACAGAGGACAACTCGGTGTACAGCGCAGACTACGTCATGGTTTCTGCGAGCCTGGGTGTCCTGCAATCCGATCTCATTCAGTTCAAGCCCAAGCTACCTACATGGAAGGTTAGGGCGATCTACCAATTCGACATGGCCGTGTACACCAAGATCTTCCTCAAGTTCCCCAGGAAGTTCTGGCCTGAAGGGAAAGGAAGGGAGTTCTTCCTCTACGCCAGCAGCAGGAGAGGTTACTACGGAGTGTGGCAGGAGTTCGAGAAGCAGTACCCTGACGCCAATGTCCTCCTGGTCACCGTGACCGACGAGGAGTCGAGGCGCATCGAGCAGCAGTCGGACGAGCAGACCAAGGCGGAGATCATGCAGGTGCTGCGGAAGATGTTCCCCGGCAAGGACGTCCCGGACGCCACCGACATCCTTGTCCCGAGGTGGTGGTCCGACAGGTTCTACAAGGGCACCTTCTCCAACTGGCCAGTTGGCGTCAACCGCTACGAATACGACCAGCTTAGGGCACCGGTTGGGAGGGTATACTTCACCGGCGAGCACACCAGCGAGCACTACAATGGCTATGTCCATGGAGCCTATCTTTCAGGTATCGACTCCGCTGAAATTCTCATCAACTGCGCCCAGAAAAAGATGTGCAAGTACCATGTCCAGGGAAAGTATGACTAGGAAGCTACAGCAAATTGATTTAAAGCTCCAGCAAATTGAGCAGTGTGGATGTTGCATTTCTCAGTTCATTTTTTCCCTGTTTTCAACAAAGTATAGATGACAGCCATGTTCCCTCGCGGCATATGCCTTTTCATTATTCCAATAAAGCTAGCGGCTGGTTCGATGAGCACGATTTGTGATCGAGTATCCTGTTTAATAAGTACGGTGTTTGCTTTTTTTTTCATGATGAGGGGTGCATGGCTTATGATATTCTATCTATTTGCTAATCAAAACTTTGTACCATGGG
  • >Zm00001eb413630_T001
    TGTATATATATGAGGGGTGAGAGGGGGGAGGGGCCTGGGGAGCAACACAAGCACTCCACACTGCTGTGCAGAACGAGAGCGTAACCATCAGTACTCAATAGTTAGAGCGACCAATAGATGAGTTCCTCCCCGTCCTTTGGTCTCCTGGCCTTAGCAGCAGTACTCCTAGCACTGAACTTAGCACAACATGGCTCCCTCGCCGCAACCGTCGGCCCCAGGGTCATCGTCGTCGGCGCCGGCATGTCTGGGATCTCGGCGGCGAAGAGGCTGTCGGAGGCCGGGATAACCGACCTGCTGATTCTGGAAGCGACGGACCACATCGGCGGGCGGATGCACAAGACGAACTTCGCCGGCATCAACGTCGAGTTAGGCGCCAACTGGGTGGAGGGCGTGAACGGCGGCAAGATGAACCCCATCTGGCCCATCGTCAACTCCACCCTCAAGCTCCGCAACTTCCGCTCCGACTTCGACTACCTCGCTCAGAACGTCTACAAGGAGGACGGTGGCGTCTACGATGAAGATTACGTCCAGAAGAGAATTGAACTGGCGGACAGCGTGGAAGAGATGGGGGAGAAGCTCTCTGCCACTTTGCACGCCAGTGGCAGAGACGACATGTCTATCCTTGCCATGCAGCGCCTCAACGAACAGTACGTGTGTCCTATATATACCTGCAGCTCCTCAACACATACATACATACATACATACAACAACAGCTGAATGCAATGCAATGCAATGGGCATGTGCATGCAGCCAGCCGAACGGGCCGGCGACGCCGGTGGACATGGTGGTGGACTACTACAAGTTCGACTACGAGTTCGCGGAGCCGCCGCGCGTGACCAGCCTGCAGAACACCGTGCCTCTCGCGACCTTCAGCGACTTCGGCGACGACGTCTACTTCGTCGCCGACCAGCGGGGCTACGAGGCCGTCGTCTACTACCTCGCCGGCCAGTACCTCAAGACCGACGATAAGTCTGGAAAGATCGTCGACCCGCGCCTGCAGCTCAACAAGGTGGTGCGAGAGATCAAGTATTCCCCGGGTGGCGTCACCGTCAAGACAGAGGACAACTCGGTGTACAGCGCAGACTACGTCATGGTTTCTGCGAGCCTGGGTGTCCTGCAATCCGATCTCATTCAGTTCAAGCCCAAGCTACCTACATGGAAGGTTAGGGCGATCTACCAATTCGACATGGCCGTGTACACCAAGATCTTCCTCAAGTTCCCCAGGAAGTTCTGGCCTGAAGGGAAAGGAAGGGAGTTCTTCCTCTACGCCAGCAGCAGGAGAGGTTACTACGGAGTGTGGCAGGAGTTCGAGAAGCAGTACCCTGACGCCAATGTCCTCCTGGTCACCGTGACCGACGAGGAGTCGAGGCGCATCGAGCAGCAGTCGGACGAGCAGACCAAGGCGGAGATCATGCAGGTGCTGCGGAAGATGTTCCCCGGCAAGGACGTCCCGGACGCCACCGACATCCTTGTCCCGAGGTGGTGGTCCGACAGGTTCTACAAGGGCACCTTCTCCAACTGGCCAGTTGGCGTCAACCGCTACGAATACGACCAGCTTAGGGCACCGGTTGGGAGGGTATACTTCACCGGCGAGCACACCAGCGAGCACTACAATGGCTATGTCCATGGAGCCTATCTTTCAGGTATCGACTCCGCTGAAATTCTCATCAACTGCGCCCAGAAAAAGATGTGCAAGTACCATGTCCAGGGAAAGTATGACTAGGAAGCTACAGCAAATTGATTTAAAGCTCCAGCAAATTGAGCAGTGTGGATGTTGCATTTCTCAGTTCATTTTTTCCCTGTTTTCAACAAAGTATAGATGACAGCCATGTTCCCTCGCGGCATATGCCTTTTCATTATTCCAATAAAGCTAGCGGCTGGTTCGATGAGCACGATTTGTGATCGAGTATCCTGTTTAATAAGTACGGTGTTTGCTTTTTTTTTCATGATGAGGGGTGCATGGCTTATGATATTCTATCTATTTGCTAATCAAAACTTTGTACCATGGG
CDS Sequence
  • >Zm00001eb413630_T002
    ATGAAGATTACGTCCAGAAGAGAATTGAACTGGCGGACAGCGTGGAAGAGATGGGGGAGAAGCTCTCTGCCACTTTGCACGCCAGTGGCAGAGACGACATGTCTATCCTTGCCATGCAGCGCCTCAACGAACAGTACGTGTGTCCTATATATACCTGCAGCTCCTCAACACATACATACATACATACATACAACAACAGCTGAATGCAATGCAATGCAATGGGCATGTGCATGCAGCCAGCCGAACGGGCCGGCGACGCCGGTGGACATGGTGGTGGACTACTACAAGTTCGACTACGAGTTCGCGGAGCCGCCGCGCGTGACCAGCCTGCAGAACACCGTGCCTCTCGCGACCTTCAGCGACTTCGGCGACGACGTCTACTTCGTCGCCGACCAGCGGGGCTACGAGGCCGTCGTCTACTACCTCGCCGGCCAGTACCTCAAGACCGACGATAAGTCTGGAAAGATCGTCGACCCGCGCCTGCAGCTCAACAAGGTGGTGCGAGAGATCAAGTATTCCCCGGGTGGCGTCACCGTCAAGACAGAGGACAACTCGGTGTACAGCGCAGACTACGTCATGGTTTCTGCGAGCCTGGGTGTCCTGCAATCCGATCTCATTCAGTTCAAGCCCAAGCTACCTACATGGAAGGTTAGGGCGATCTACCAATTCGACATGGCCGTGTACACCAAGATCTTCCTCAAGTTCCCCAGGAAGTTCTGGCCTGAAGGGAAAGGAAGGGAGTTCTTCCTCTACGCCAGCAGCAGGAGAGGTTACTACGGAGTGTGGCAGGAGTTCGAGAAGCAGTACCCTGACGCCAATGTCCTCCTGGTCACCGTGACCGACGAGGAGTCGAGGCGCATCGAGCAGCAGTCGGACGAGCAGACCAAGGCGGAGATCATGCAGGTGCTGCGGAAGATGTTCCCCGGCAAGGACGTCCCGGACGCCACCGACATCCTTGTCCCGAGGTGGTGGTCCGACAGGTTCTACAAGGGCACCTTCTCCAACTGGCCAGTTGGCGTCAACCGCTACGAATACGACCAGCTTAGGGCACCGGTTGGGAGGGTATACTTCACCGGCGAGCACACCAGCGAGCACTACAATGGCTATGTCCATGGAGCCTATCTTTCAGGTATCGACTCCGCTGAAATTCTCATCAACTGCGCCCAGAAAAAGATGTGCAAGTACCATGTCCAGGGAAAGTATGACTAG
  • >Zm00001eb413630_T001
    ATGAAGATTACGTCCAGAAGAGAATTGAACTGGCGGACAGCGTGGAAGAGATGGGGGAGAAGCTCTCTGCCACTTTGCACGCCAGTGGCAGAGACGACATGTCTATCCTTGCCATGCAGCGCCTCAACGAACAGTACGTGTGTCCTATATATACCTGCAGCTCCTCAACACATACATACATACATACATACAACAACAGCTGAATGCAATGCAATGCAATGGGCATGTGCATGCAGCCAGCCGAACGGGCCGGCGACGCCGGTGGACATGGTGGTGGACTACTACAAGTTCGACTACGAGTTCGCGGAGCCGCCGCGCGTGACCAGCCTGCAGAACACCGTGCCTCTCGCGACCTTCAGCGACTTCGGCGACGACGTCTACTTCGTCGCCGACCAGCGGGGCTACGAGGCCGTCGTCTACTACCTCGCCGGCCAGTACCTCAAGACCGACGATAAGTCTGGAAAGATCGTCGACCCGCGCCTGCAGCTCAACAAGGTGGTGCGAGAGATCAAGTATTCCCCGGGTGGCGTCACCGTCAAGACAGAGGACAACTCGGTGTACAGCGCAGACTACGTCATGGTTTCTGCGAGCCTGGGTGTCCTGCAATCCGATCTCATTCAGTTCAAGCCCAAGCTACCTACATGGAAGGTTAGGGCGATCTACCAATTCGACATGGCCGTGTACACCAAGATCTTCCTCAAGTTCCCCAGGAAGTTCTGGCCTGAAGGGAAAGGAAGGGAGTTCTTCCTCTACGCCAGCAGCAGGAGAGGTTACTACGGAGTGTGGCAGGAGTTCGAGAAGCAGTACCCTGACGCCAATGTCCTCCTGGTCACCGTGACCGACGAGGAGTCGAGGCGCATCGAGCAGCAGTCGGACGAGCAGACCAAGGCGGAGATCATGCAGGTGCTGCGGAAGATGTTCCCCGGCAAGGACGTCCCGGACGCCACCGACATCCTTGTCCCGAGGTGGTGGTCCGACAGGTTCTACAAGGGCACCTTCTCCAACTGGCCAGTTGGCGTCAACCGCTACGAATACGACCAGCTTAGGGCACCGGTTGGGAGGGTATACTTCACCGGCGAGCACACCAGCGAGCACTACAATGGCTATGTCCATGGAGCCTATCTTTCAGGTATCGACTCCGCTGAAATTCTCATCAACTGCGCCCAGAAAAAGATGTGCAAGTACCATGTCCAGGGAAAGTATGACTAG
Protein Sequence
  • >Zm00001eb413630_P002
    MKITSRRELNWRTAWKRWGRSSLPLCTPVAETTCLSLPCSASTNSTCVLYIPAAPQHIHTYIHTTTAECNAMQWACACSQPNGPATPVDMVVDYYKFDYEFAEPPRVTSLQNTVPLATFSDFGDDVYFVADQRGYEAVVYYLAGQYLKTDDKSGKIVDPRLQLNKVVREIKYSPGGVTVKTEDNSVYSADYVMVSASLGVLQSDLIQFKPKLPTWKVRAIYQFDMAVYTKIFLKFPRKFWPEGKGREFFLYASSRRGYYGVWQEFEKQYPDANVLLVTVTDEESRRIEQQSDEQTKAEIMQVLRKMFPGKDVPDATDILVPRWWSDRFYKGTFSNWPVGVNRYEYDQLRAPVGRVYFTGEHTSEHYNGYVHGAYLSGIDSAEILINCAQKKMCKYHVQGKYD
  • >Zm00001eb413630_P001
    MKITSRRELNWRTAWKRWGRSSLPLCTPVAETTCLSLPCSASTNSTCVLYIPAAPQHIHTYIHTTTAECNAMQWACACSQPNGPATPVDMVVDYYKFDYEFAEPPRVTSLQNTVPLATFSDFGDDVYFVADQRGYEAVVYYLAGQYLKTDDKSGKIVDPRLQLNKVVREIKYSPGGVTVKTEDNSVYSADYVMVSASLGVLQSDLIQFKPKLPTWKVRAIYQFDMAVYTKIFLKFPRKFWPEGKGREFFLYASSRRGYYGVWQEFEKQYPDANVLLVTVTDEESRRIEQQSDEQTKAEIMQVLRKMFPGKDVPDATDILVPRWWSDRFYKGTFSNWPVGVNRYEYDQLRAPVGRVYFTGEHTSEHYNGYVHGAYLSGIDSAEILINCAQKKMCKYHVQGKYD

Source: Genetic information comes from the article