Gene Details:
- Gene ID: Zm00001eb231210
- Gene Symbol: ZmNRAMP4 ZmNRAMP6 nrat2
- Gene Name: nramp aluminum transporter2
- Genome: Zm-B73-REFERENCE-NAM-5.0
- Species: Zea mays
Functional Descriptions:
- A metal transporter ZmNRAMP6 was identified by using a trait-associated co-expression network analysis at a genome-wide level. ZmNRAMP6 confers maize sensitivity to Pb by accumulating it to maize shoots. ZmNRAMP6 knockout detains Pb in roots, activates antioxidant enzymes, and improves Pb tolerance.
- ZmNRAMP6 that encodes a metal transporter was identified as the key gene among the Pb tolerance-associated co-expression module. Heterologous expression of ZmNRAMP6 in yeast verified its role in Pb transport.
- knockout mutant(nrat2) detains Pb in roots, activates antioxidant enzymes, and improves Pb tolerance.
Function-related keywords:
Literature:
- A genome-wide co-expression network analysis revealed ZmNRAMP6-mediated regulatory pathway involved in maize tolerance to lead stress. DOI: 10.1007/s00122-023-04371-5 ; PMID: 37142873
Related News:
Gene Resources:
- NCBI ID: LOC103626569
- UniProt accessions: A0A1D6GZH2
Sequences:
cDNA Sequence
- >Zm00001eb231210_T001
CTCGGGGTCTGAAACTTTTCTTCCCACAAATGTATAGCGAGGGTTCAGATCTCAAAGCATATAATAATGCGAAGACAGCTAGTCACCTGCTCTTGTACTGCACTGCACTCCAGGCCTCAGTGCCTGCATGGGGGAGTCTTCACCGGGTGTCCGGGCAGGCACATCACTAGCTAGTACAGAAAATGGAGCAGGCCGGTGACGAGACGCCGGGAGAGATCGGGCGAGAGGCTGCTCGCCGTGAAGCTGCGCTCCGGAGCGGCGGCGGAGACGCCGGAGAGCGCGTAGACAAGGCTGTGGTGGACGGCGGAGAAGACGAGCGGTTTCGCGTGCAGCGGAAATGGAGGCGGTTCTTGGCCCATGTCGGGCCCGGAGCTCTCGTGGCCATTGGCTTCCTGGATCCTAGCAACTTGGAAACCGACATGCAAGCTGGGGCTGACTTCAAGTACCAGCTTCTGTGGGTGATTTTAGTCGGGATGGTCTTCGCGCTTCTGATCCAAACACTGGCCGCCAACCTTGGAGTGAAGACAGGCAAGCATCTCGCTGAGCTCTGCAGGGAAGAGTACCCACGTTCCGTCAACATCTGCCTGTGGATCATCGCGGAGCTGGCGGTGATATCCGACGACATCCCCGAAGTGCTGGGCACAGCCTTCGCGTTCAACATCCTGCTCGGGATCCCGGTGTGGGCCGGAGTCGTCCTCACGGTGCTCAGCACGCTGCTGCTCCTCGGGGTGGAGAGATTCGGGGCCCGCAAGCTGGAGTTCGTCGTGGCAGCTTTCATGTTCGCCATGGCGGCCTGCTTCTTCGGGGAGCTGAGCTACCTGAGGCCGTCCGCGGGGGAGGTTGTCGAGGGCATGTTCGTCCCCAGGCTCCGAGGGAAAGGCGCGGCAGCCAACGCCATCGCGCTCTTCGGCGCCATCATCACGCCGTACAACCTGTTCCTGCACTCGGCGCTTGTGCTCTCCAGGAAGACCCCGCGGTCAGTGAAAAGCATCAGGGCCGCGTGCAGGTACTTCCTCGTGGAGTGCAGCCTGGCGTTCGTGGTGGCGTTCCTCATCAACGTGGCGGTGGTCGTCGTCGCCGGGTCCATCTGCAACGCGGCGGGCGGCAACCTGTCCCCGGCCGACGCGGCCGCGTGCGGCGACCTCACTCTGCAGTCCACGCCTCTGCTGCTCAGGGACGTTCTGGGGAGGTCGAGCTCCGTCGTGTACGCCGTCGCGCTGCTGGCGTCCGGGCAGAGCACCACCATCAGCTGCACGTTTGCCGGGCAGGTTATCATGCAGGGGTTCCTGGACATGAGGATGAAGAGCTGGGTGCGGAACCTGACCACGCGCGCCATCGCCATCGCCCCCAGCCTCGTCGTCTCCATCGTCAGCGGCCCGTCGGGTGCTGGCAAGCTCATCGTCTTCTCGTCGATGGTGCTGTCGTTCGAGCTGCCATTCGCGCTCATCCCGCTCCTCAAGTTCTGCAACAGCAGCAACAAAGTCGGGCCCCTCAAGGAGTCCATCTACACGGTGGTGATCGCGTGGGCGCTGAGCTTCGCGCTCATCGTGGTGAACACCTACTTCCTGGTGTGGACGTACGTGGACTGGCTGGTGCACAGTCGGCTCCCCAAGTACGCCACCGCGCTCCTCTCCGTCGCCGTCCTGGCGCTCATGGCCGCCTACCTCGCCTTCGTCGTCTACCTGGCGTTCAGGAGGGACGCGGTGCGCACGTACGTGCCGGTGTCGGAGCGGGCGGAGGACGGCAGCGGGTCGCAGGCGGTGGCGGCGGCGGCCTCCGCCGACGACGCTGACATGCCGGCGCCGTTCAGGAAGGACCTGGCTGATGCTTCCACGTAGACACGGAGATGCTCTCGTTCGGGCAGTGACCATATCGATCAATCCTGTTCATGCATATGATTTGTGGATCGTCGTCGAGAGGCGTGCTGGCTCATTCGTCTGCTCAGTGACCGAATTTGTTCGTGTACGTAGATTATCATAAGATCTTACACGCAGCCGCATACCAAGCCACACGAACCTTCGTGTACGGTTTTGATATATCCCATATCCAACAGTTCATCCATGTTTTACAATATAGATAATATTATTCGCAGAGTAAAGTTTAAATATAAATATAAAAATGAGTAAGTTGCTAAAAATAGTCTAAGAACTATTTGAGACAAATAAAAACTAGCTTTGCTCCACCAATACAATAGTTTTCCTATCCTACATCATATTCCTCTCCTATTTCAAGCTCTACTGTGTTTACGTATCTCTCTCCTTCACATAGACCTTTACTATTTCAAACTCTACCATATAAACAGTATATCTTACAATGCATCATATCCCTATCCTATTTCAAACTCTACCATATAAACATTATATGTTACAATGCTACATCGTATCCCTC
CDS Sequence
- >Zm00001eb231210_T001
ATGGAGCAGGCCGGTGACGAGACGCCGGGAGAGATCGGGCGAGAGGCTGCTCGCCGTGAAGCTGCGCTCCGGAGCGGCGGCGGAGACGCCGGAGAGCGCGTAGACAAGGCTGTGGTGGACGGCGGAGAAGACGAGCGGTTTCGCGTGCAGCGGAAATGGAGGCGGTTCTTGGCCCATGTCGGGCCCGGAGCTCTCGTGGCCATTGGCTTCCTGGATCCTAGCAACTTGGAAACCGACATGCAAGCTGGGGCTGACTTCAAGTACCAGCTTCTGTGGGTGATTTTAGTCGGGATGGTCTTCGCGCTTCTGATCCAAACACTGGCCGCCAACCTTGGAGTGAAGACAGGCAAGCATCTCGCTGAGCTCTGCAGGGAAGAGTACCCACGTTCCGTCAACATCTGCCTGTGGATCATCGCGGAGCTGGCGGTGATATCCGACGACATCCCCGAAGTGCTGGGCACAGCCTTCGCGTTCAACATCCTGCTCGGGATCCCGGTGTGGGCCGGAGTCGTCCTCACGGTGCTCAGCACGCTGCTGCTCCTCGGGGTGGAGAGATTCGGGGCCCGCAAGCTGGAGTTCGTCGTGGCAGCTTTCATGTTCGCCATGGCGGCCTGCTTCTTCGGGGAGCTGAGCTACCTGAGGCCGTCCGCGGGGGAGGTTGTCGAGGGCATGTTCGTCCCCAGGCTCCGAGGGAAAGGCGCGGCAGCCAACGCCATCGCGCTCTTCGGCGCCATCATCACGCCGTACAACCTGTTCCTGCACTCGGCGCTTGTGCTCTCCAGGAAGACCCCGCGGTCAGTGAAAAGCATCAGGGCCGCGTGCAGGTACTTCCTCGTGGAGTGCAGCCTGGCGTTCGTGGTGGCGTTCCTCATCAACGTGGCGGTGGTCGTCGTCGCCGGGTCCATCTGCAACGCGGCGGGCGGCAACCTGTCCCCGGCCGACGCGGCCGCGTGCGGCGACCTCACTCTGCAGTCCACGCCTCTGCTGCTCAGGGACGTTCTGGGGAGGTCGAGCTCCGTCGTGTACGCCGTCGCGCTGCTGGCGTCCGGGCAGAGCACCACCATCAGCTGCACGTTTGCCGGGCAGGTTATCATGCAGGGGTTCCTGGACATGAGGATGAAGAGCTGGGTGCGGAACCTGACCACGCGCGCCATCGCCATCGCCCCCAGCCTCGTCGTCTCCATCGTCAGCGGCCCGTCGGGTGCTGGCAAGCTCATCGTCTTCTCGTCGATGGTGCTGTCGTTCGAGCTGCCATTCGCGCTCATCCCGCTCCTCAAGTTCTGCAACAGCAGCAACAAAGTCGGGCCCCTCAAGGAGTCCATCTACACGGTGGTGATCGCGTGGGCGCTGAGCTTCGCGCTCATCGTGGTGAACACCTACTTCCTGGTGTGGACGTACGTGGACTGGCTGGTGCACAGTCGGCTCCCCAAGTACGCCACCGCGCTCCTCTCCGTCGCCGTCCTGGCGCTCATGGCCGCCTACCTCGCCTTCGTCGTCTACCTGGCGTTCAGGAGGGACGCGGTGCGCACGTACGTGCCGGTGTCGGAGCGGGCGGAGGACGGCAGCGGGTCGCAGGCGGTGGCGGCGGCGGCCTCCGCCGACGACGCTGACATGCCGGCGCCGTTCAGGAAGGACCTGGCTGATGCTTCCACGTAG
Protein Sequence
- >Zm00001eb231210_P001
MEQAGDETPGEIGREAARREAALRSGGGDAGERVDKAVVDGGEDERFRVQRKWRRFLAHVGPGALVAIGFLDPSNLETDMQAGADFKYQLLWVILVGMVFALLIQTLAANLGVKTGKHLAELCREEYPRSVNICLWIIAELAVISDDIPEVLGTAFAFNILLGIPVWAGVVLTVLSTLLLLGVERFGARKLEFVVAAFMFAMAACFFGELSYLRPSAGEVVEGMFVPRLRGKGAAANAIALFGAIITPYNLFLHSALVLSRKTPRSVKSIRAACRYFLVECSLAFVVAFLINVAVVVVAGSICNAAGGNLSPADAAACGDLTLQSTPLLLRDVLGRSSSVVYAVALLASGQSTTISCTFAGQVIMQGFLDMRMKSWVRNLTTRAIAIAPSLVVSIVSGPSGAGKLIVFSSMVLSFELPFALIPLLKFCNSSNKVGPLKESIYTVVIAWALSFALIVVNTYFLVWTYVDWLVHSRLPKYATALLSVAVLALMAAYLAFVVYLAFRRDAVRTYVPVSERAEDGSGSQAVAAAASADDADMPAPFRKDLADAST
Source: Genetic information comes from the article