Information report for ZmMYC2a;bhlh149
Gene Details
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Functional Descriptions
- We generated maize mutants in which ZmMYC2a and ZmMYC2b, two transcription factor genes important in JA signaling, were individually or both knocked out.
- ZmMYC2s play important roles in maize responses to simulated herbivory and jasmonate.
- ZmMYC2a and ZmMYC2b played a redundant role in maize resistance to insects and JA signaling.
- CUT&Tag-Seq and dual luciferase assays revealed that ZmMYC2s transactivate the benzoxazinoid and volatile terpene biosynthesis genes IGPS1/3, BX10/11/12/14, and TPS10/2/3/4/5/8 by directly binding to their promoters.
- Double mutant with myc7 (ZmMYC2a) was highly susceptible to insects, and the levels of benzoxazinoids and volatile terpenes, and the levels of their biosynthesis gene transcripts, were much lower.double mutant with myc7 (ZmMYC2a) was highly susceptible to insects, and the levels of benzoxazinoids and volatile terpenes, and the levels of their biosynthesis gene transcripts, were much lower.double mutant with myc7 (ZmMYC2a) was highly susceptible to insects, and the levels of benzoxazinoids and volatile terpenes, and the levels of their biosynthesis gene transcripts, were much lower.
Functional Keywords
Literature and News
Gene Resources
- NCBI ID: LOC541694
- UniProt accessions: A0A1D6K972
- EMBL: CM007647
- EnsemblPlants: Zm00001eb024330_T001
- Gramene: Zm00001eb024330_T001
- KEGG: zma:541694
- OMA: HQIQHFE
- ExpressionAtlas: Zm00001eb024330
- InterPro: IPR011598 , IPR025610 , IPR036638 , IPR045084 , IPR054502
- PANTHER: PTHR11514 , PTHR11514:SF43
- SUPFAM: SSF47459
- PROSITE: PS50888
- Gene3D: 4.10.280.10
- OrthoDB: A0A1D6K972
- SMR: A0A1D6K972
- CDD: cd11449
Sequences
cDNA Sequence
- >Zm00001eb024330_T001
ACCCGTTTTACCTGGTCCCGCCCTGACCCCGGGCGACGACATGTTCCCGTATTTGCCCTCGCCCAGCCGGACAAGAAGCGAGACAAGCGCCCATCCTTGGCTCGGGCGTTTTCGGGTTTGCGCCATAATCCCACGGAATCCGCATTCTGAACCATTTCCTTCGCTTTCCCCTTCGCCCTCTCTCTCTCCCAGTCTCCACCCACCATTTCTCCTCCTCTTTCCGTCGGGTCTACTGCACCTTGCCCTCCCCCATGAACCTGTGGACGGACGACAACGCCTCCATGATGGAGGCCTTCATGGCTTCTGCCGACCTCCCCACCTTCCCCTGGGGAGCGCCGGCCGGGGGCGGCAACTCGTCGGCCGCCGCGGCGTCGCCGCCGCCGCCGCAGATGCCAGCGGCGACGGCTCCCGGGTTCAACCAGGACACGCTGCAGCAGAGGCTACAAGCCATGATAGAGGGGTCGAGGGAGACCTGGACCTACGCCATCTTCTGGCAGTCCTCCCTTGACTCCGCCACCGGCGCCTCGCTGCTCGGCTGGGGGGACGGCTACTACAAGGGCTGCGACGAAGACAAGCGCAAGCAGAAGCCGCTCACGCCCTCCGCCCAGGCCGAGCAGGAGCACCGCAAGCGCGTGCTCCGCGAGCTCAACTCCCTCATCTCCGGCGCGGCGGCGGCTCCCGACGAGGCCGTCGAGGAGGAGGTCACCGATACCGAGTGGTTCTTCCTCGTCTCCATGACGCAGTCGTTTCTCAACGGTTCGGGCCTCCCCGGGCAGGCGCTCTTCGCCGGGCAGCCCACATGGATCGCCTCTGGCCTCTCCTCCGCGCCGTGCGAGCGCGCGCGTCAGGCCTACAACTTCGGCCTCCGCACCATGGTCTGCTTCCCCGTCGGCACCGGGGTGCTCGAGCTCGGCTCCACCGACGTCGTGTTCAAGACCGCCGAGAGCATGGCTAAGATCCGCTCGCTCTTTGGGGGCGGAGCAGGGGGTGGCTCGTGGCCGCCCGTGCAGCCTCAGGCGCCGTCGTCGCAGCAGCCCGCCGCCGGAGCCGACCACGCGGAGACGGACCCGTCCATGCTATGGCTCGCCGACGCGCCGGTCATGGACATCAAGGATTCCTTGTCGCACCCGTCGGCCGAGATCTCCGTCTCCAAGCCTCCGCCGCATCCGCCGCAGATCCATTTTGAGAACGGGAGCACGAGCACGCTCACGGAGAACCCCAGCCCCTCCGTGCACGCGCCGCCACCCCCGCCGGCGCCGGCTGCTCCACAGCAGCGGCAGCACCAGCACCAGAATCAGGCGCACCAGGGCCCGTTCCGCCGGGAGCTCAATTTCTCGGACTTCGCGTCCACTCCTTCCTTGGCGGCGACCCCGCCGTTCTTCAAGCCCGAGTCCGGCGAGATCCTCAGCTTCGGCGCCGACAGCAACGCCCGGAGGAACCCGTCGCCGGTACCTCCCGCCGCCACCGCCAGCCTCACCACCGCTCCCGGGAGCCTCTTCTCGCAGCACACGGCGACCATGACGGCCGCCGCGGCGAACGACGCGAAGAACAACAACAAGCGCTCAATGGAGGCCACCTCCCGGGCGAGCAACACCAACCACCACCCGGCGGCGACGGCGAACGAGGGCATGCTGTCCTTCTCGTCGGCGCCGACTACGCGGCCGTCGACGGGCACGGGCGCGCCGGCCAAGTCGGAGTCCGACCACTCGGACCTGGACGCGTCTGTGCGCGAGGTGGAGAGCAGCCGCGTGGTGGCGCCGCCACCGGAGGCGGAGAAGCGGCCGCGAAAGCGCGGGCGGAAGCCCGCGAACGGGCGCGAGGAGCCGCTGAACCACGTGGAGGCGGAGCGGCAGCGGCGGGAGAAGCTGAACCAGCGCTTCTACGCGCTGCGCGCCGTGGTGCCCAACGTGTCGAAGATGGACAAGGCGTCGCTGCTCGGCGACGCCATCTCCTACATCAACGAGCTCCGGGGCAAGCTGACGTCGCTGGAGACCGACAAGGAGACGCTGCAGACCCAGGTGGAGGCGCTCAAGAAGGAGCGCGACGCGCGGCCGCCCTCGCACTCCGCTGGGCTCGGCGGGCACGACGGCGGGCCGCGCTGCCACGCGGTGGAGATCGACGCCAAGATCCTGGGGCTGGAGGCCATGATCCGCGTGCAGTGCCACAAGCGCAACCACCCGTCGGCGCGGCTGATGACAGCGCTCCGCGAGCTCGACCTGGACGTGTACCACGCCAGCGTGTCCGTCGTCAAGGACCTCATGATCCAGCAGGTCGCCGTCAAGATGGCCAGCCGCGTGTACACGCAGGACCAGCTCAGCGCCGCGCTCTACAGCCGCCTCGCGGAGCCCGGGTCTGCCATGGGCAGGTAATCAAGGAGGAGAGCTGCTCAGCTCGCCTGTGGCTGCCGGATTAGGGGACGACACTGATACTACTGCTACTCACCACCGGACTGTCCTGTCGTCGTGGTCACCACGGTTACAACACGATAGGCAGAAAGATTCAGGAGGGAGGGAGACGACGACGATGCCGGTGCTGTATAAACTTTAGAAGGATGGATGGATGGATGATGATACCGAGCTTCTGCTGCTGTTCATCATCATCTTCTTGTGTTTTTGCTAGTAGCGTGTTAATTAGCAGGATTAAGCAACCAACAAGTGTCCAACCGTTGTTGTTAATTAAGTACATGTTGTGAGC
CDS Sequence
- >Zm00001eb024330_T001
ATGAACCTGTGGACGGACGACAACGCCTCCATGATGGAGGCCTTCATGGCTTCTGCCGACCTCCCCACCTTCCCCTGGGGAGCGCCGGCCGGGGGCGGCAACTCGTCGGCCGCCGCGGCGTCGCCGCCGCCGCCGCAGATGCCAGCGGCGACGGCTCCCGGGTTCAACCAGGACACGCTGCAGCAGAGGCTACAAGCCATGATAGAGGGGTCGAGGGAGACCTGGACCTACGCCATCTTCTGGCAGTCCTCCCTTGACTCCGCCACCGGCGCCTCGCTGCTCGGCTGGGGGGACGGCTACTACAAGGGCTGCGACGAAGACAAGCGCAAGCAGAAGCCGCTCACGCCCTCCGCCCAGGCCGAGCAGGAGCACCGCAAGCGCGTGCTCCGCGAGCTCAACTCCCTCATCTCCGGCGCGGCGGCGGCTCCCGACGAGGCCGTCGAGGAGGAGGTCACCGATACCGAGTGGTTCTTCCTCGTCTCCATGACGCAGTCGTTTCTCAACGGTTCGGGCCTCCCCGGGCAGGCGCTCTTCGCCGGGCAGCCCACATGGATCGCCTCTGGCCTCTCCTCCGCGCCGTGCGAGCGCGCGCGTCAGGCCTACAACTTCGGCCTCCGCACCATGGTCTGCTTCCCCGTCGGCACCGGGGTGCTCGAGCTCGGCTCCACCGACGTCGTGTTCAAGACCGCCGAGAGCATGGCTAAGATCCGCTCGCTCTTTGGGGGCGGAGCAGGGGGTGGCTCGTGGCCGCCCGTGCAGCCTCAGGCGCCGTCGTCGCAGCAGCCCGCCGCCGGAGCCGACCACGCGGAGACGGACCCGTCCATGCTATGGCTCGCCGACGCGCCGGTCATGGACATCAAGGATTCCTTGTCGCACCCGTCGGCCGAGATCTCCGTCTCCAAGCCTCCGCCGCATCCGCCGCAGATCCATTTTGAGAACGGGAGCACGAGCACGCTCACGGAGAACCCCAGCCCCTCCGTGCACGCGCCGCCACCCCCGCCGGCGCCGGCTGCTCCACAGCAGCGGCAGCACCAGCACCAGAATCAGGCGCACCAGGGCCCGTTCCGCCGGGAGCTCAATTTCTCGGACTTCGCGTCCACTCCTTCCTTGGCGGCGACCCCGCCGTTCTTCAAGCCCGAGTCCGGCGAGATCCTCAGCTTCGGCGCCGACAGCAACGCCCGGAGGAACCCGTCGCCGGTACCTCCCGCCGCCACCGCCAGCCTCACCACCGCTCCCGGGAGCCTCTTCTCGCAGCACACGGCGACCATGACGGCCGCCGCGGCGAACGACGCGAAGAACAACAACAAGCGCTCAATGGAGGCCACCTCCCGGGCGAGCAACACCAACCACCACCCGGCGGCGACGGCGAACGAGGGCATGCTGTCCTTCTCGTCGGCGCCGACTACGCGGCCGTCGACGGGCACGGGCGCGCCGGCCAAGTCGGAGTCCGACCACTCGGACCTGGACGCGTCTGTGCGCGAGGTGGAGAGCAGCCGCGTGGTGGCGCCGCCACCGGAGGCGGAGAAGCGGCCGCGAAAGCGCGGGCGGAAGCCCGCGAACGGGCGCGAGGAGCCGCTGAACCACGTGGAGGCGGAGCGGCAGCGGCGGGAGAAGCTGAACCAGCGCTTCTACGCGCTGCGCGCCGTGGTGCCCAACGTGTCGAAGATGGACAAGGCGTCGCTGCTCGGCGACGCCATCTCCTACATCAACGAGCTCCGGGGCAAGCTGACGTCGCTGGAGACCGACAAGGAGACGCTGCAGACCCAGGTGGAGGCGCTCAAGAAGGAGCGCGACGCGCGGCCGCCCTCGCACTCCGCTGGGCTCGGCGGGCACGACGGCGGGCCGCGCTGCCACGCGGTGGAGATCGACGCCAAGATCCTGGGGCTGGAGGCCATGATCCGCGTGCAGTGCCACAAGCGCAACCACCCGTCGGCGCGGCTGATGACAGCGCTCCGCGAGCTCGACCTGGACGTGTACCACGCCAGCGTGTCCGTCGTCAAGGACCTCATGATCCAGCAGGTCGCCGTCAAGATGGCCAGCCGCGTGTACACGCAGGACCAGCTCAGCGCCGCGCTCTACAGCCGCCTCGCGGAGCCCGGGTCTGCCATGGGCAGGTAA
Protein Sequence
- >Zm00001eb024330_P001
MNLWTDDNASMMEAFMASADLPTFPWGAPAGGGNSSAAAASPPPPQMPAATAPGFNQDTLQQRLQAMIEGSRETWTYAIFWQSSLDSATGASLLGWGDGYYKGCDEDKRKQKPLTPSAQAEQEHRKRVLRELNSLISGAAAAPDEAVEEEVTDTEWFFLVSMTQSFLNGSGLPGQALFAGQPTWIASGLSSAPCERARQAYNFGLRTMVCFPVGTGVLELGSTDVVFKTAESMAKIRSLFGGGAGGGSWPPVQPQAPSSQQPAAGADHAETDPSMLWLADAPVMDIKDSLSHPSAEISVSKPPPHPPQIHFENGSTSTLTENPSPSVHAPPPPPAPAAPQQRQHQHQNQAHQGPFRRELNFSDFASTPSLAATPPFFKPESGEILSFGADSNARRNPSPVPPAATASLTTAPGSLFSQHTATMTAAAANDAKNNNKRSMEATSRASNTNHHPAATANEGMLSFSSAPTTRPSTGTGAPAKSESDHSDLDASVREVESSRVVAPPPEAEKRPRKRGRKPANGREEPLNHVEAERQRREKLNQRFYALRAVVPNVSKMDKASLLGDAISYINELRGKLTSLETDKETLQTQVEALKKERDARPPSHSAGLGGHDGGPRCHAVEIDAKILGLEAMIRVQCHKRNHPSARLMTALRELDLDVYHASVSVVKDLMIQQVAVKMASRVYTQDQLSAALYSRLAEPGSAMGR