Gene Details:
- Gene ID: Zm00001eb211390
- Gene Symbol: ZmLAZ1-4 laz4
- Gene Name: lazarus ortholog4
- Genome: Zm-B73-REFERENCE-NAM-5.0
- Species: Zea mays
Functional Descriptions:
- Zinc Transporter ZmLAZ1-4 Modulates Zinc Homeostasis on Plasma and Vacuolar Membrane in Maize.
- Heterologous expression of ZmLAZ1-4 in the zinc-sensitive yeast mutant, Arabidopsis, and maize significantly facilitated the accumulation of Zn2+ in transgenic lines, respectively. The result of subcellular localization exhibited that ZmLAZ1-4 was localized on the plasma and vacuolar membrane, as well as chloroplast.
- ZmLAZ1-4 was a novel zinc transporter on plasma and vacuolar membrane, and transported zinc under negative regulation of the ZmBES1/BZR1-11 transcription factor. The study provides insights into further underlying the mechanism of ZmLAZ1-4 regulating zinc homeostasis.
Function-related keywords:
Literature:
- Zinc Transporter ZmLAZ1-4 Modulates Zinc Homeostasis on Plasma and Vacuolar Membrane in Maize. DOI: 10.3389/fpls.2022.881055 ; PMID: 35586216
Related News:
Gene Resources:
- NCBI ID: LOC100382518
- UniProt accessions: A0A804P6F8
Sequences:
cDNA Sequence
- >Zm00001eb211390_T002
CAGACGCGAAAAGCCGATGCTATCAACGCTAACTGTTAACCCCTCTCCGTTTGCCCAAGTGCCCAAGCCCAACCACCCGCACCAAGCCAAACCAGGACAGAGAGAGAGAGAGAGCACGCGGCGCGGCCCCGCCGAGCCGAGCGCCTGCCTGCAAGGCTCCCCTCCTCCCTTTCGCTTCCTCCTTCGATCGGCCCCGCCCAGCTGCTGCTGCTCGCGCCGCCGCGGTGAGACCCGGGAGGAGGGCCTGGTGGTGGGCGGCCCCGATGGAGTGGGCGTCGGCGGCGTACACGGCCGCGGCGCTGGTGTGCGCGGCGGCGGCGTGCGTGGTCGCGCTCGCGCACATCTACCGCCACCTCCTCCACTACGCCGAGCCAATCTACCAGCGGTTCATCGTCCGCATCATATTCATGGTCCCGGTATATGCTGTGATGTCATTCCTTTCCCTTATCCTCCCTAACAACGCGATATACTTTAATTCTATTCGGGAGATCTATGATGCTTGGGTCATCTACAATTTTCTCTCACTCTGCTTGGCATGGGTGGGAGGTCCTGGTGCTGTGGTGGCGTTTTATACGAAGATGCAAACAAGGTTGCTTGCAGTTTGTGATTCTCAAGCCTATTTTGGTTGTCATCACCTTCATACTTTACGCAAAAGGAAAATACAAAGATGGAAACTTCAGTGTCAACCAATCCTATCTCTACATAACTATCATATATACAATCTCATACTCAATGGCTTTATATGCCCTTGCATTGTTCTACGCGGCTTGCAGAGATCTACTTCGGCCATATAATCCTGTCCCAAAATTCATCATGATCAAATCAGTGGTGTTTCTCACATATTGGCAGGGCGTCCTGGTTTTCCTTGCTGCAAAATCTCGATTTATCAAGAATGCTGATAAGGCTGCTGATCTCCAGAACTTTGTGTTGTGTGTTGAGATGCTAATAGCAGCCGTTGGGCACTTATTTGCCTTCCCCTACAAGGAATATACAGGTCCCAATGCCCGCCCTTCACGTGGTTTCAGAGAAAGCCTTCTTCATGCTTTGAAATTCAATGATTTCTACCATGACACCGTTCATCAGTTTGCTCCTACATACAATGAATATGTGCTCTACAATCACAATGAGGGAGACAGTGCACAAACAAAGTATCCCTCGGGGAGCACCGCCACAAGTGGGCAGGGTGTAGAGTTGGCTGGCATCACCGTGGCGGCCTCAAACAGTCCAGTGTCGTCAAGTGTATCATCCAACCAGGCAGATCAGGAAGAAACAATGACAACCCCAATCAAGGACAAAGTTGATCCTCCTGGAGGGCTCTACGACCTCACAGAATTGCTTGATATTGATCTGTCTAGCTACCCAGCCAAGCTTCCTGGAACCACCGATGTAAGAAAACAATGATCAAGCTTGATGAGATGGGCTATTGGTAGGGTTGTTGCGATTGGGTTGGGGGAAAATCGTGATTATTATTTTTTTACTGTTGAAGAGTGCCATAGTTAACATTGTAAAAATGTGTGTATTATTTGTTCTGATTTTTCCCCCCGTTGAAGGGGGTTTATTCATTGTCAGCAGTTGCTGCCACACGGCCTCCCTCACCCTGCTCTTTATTAACCGTGTAAAATGTTGTGAGCTTAAGGTGAACCTTAGTGTCAAGGGGAGTCTATACCAGTACAATATTCTGCGTTTCTGGTGGCGTATTTTTTGTCTCTCTATCCAAGGGGCTTGTTTGGCCCTAGCCAAAATTTCTTCGTGCCTACAGCTTTGAAACATGAGCTCGGCACGCTGTCACCACAACAGGAACGTGA - >Zm00001eb211390_T003
CAGACGCGAAAAGCCGATGCTATCAACGCTAACTGTTAACCCCTCTCCGTTTGCCCAAGTGCCCAAGCCCAACCACCCGCACCAAGCCAAACCAGGACAGAGAGAGAGAGAGAGCACGCGGCGCGGCCCCGCCGAGCCGAGCGCCTGCCTGCAAGGCTCCCCTCCTCCCTTTCGCTTCCTCCTTCGATCGGCCCCGCCCAGCTGCTGCTGCTCGCGCCGCCGCGGTGAGACCCGGGAGGAGGGCCTGGTGGTGGGCGGCCCCGATGGAGTGGGCGTCGGCGGCGTACACGGCCGCGGCGCTGGTGTGCGCGGCGGCGGCGTGCGTGGTCGCGCTCGCGCACATCTACCGCCACCTCCTCCACTACGCCGAGCCAATCTACCAGCGGTTCATCGTCCGCATCATATTCATGGTCCCGGTATATGCTGTGATGTCATTCCTTTCCCTTATCCTCCCTAACAACGCGATATACTTTAATTCTATTCGGGAGATCTATGATGCTTGGGTCATCTACAATTTTCTCTCACTCTGCTTGGCATGGGTGGGAGGTCCTGGTGCTGTGGTGGCGTTTTATACGAAGATGCAAACAAGGTTGCTTGCAGTTTGTGATTCTCAAGCCTATTTTGGTTGTCATCACCTTCATACTTTACGCAAAAGGAAAATACAAAGATGGAAACTTCAGTGTCAACCAATCCTATCTCTACATAACTATCATATATACAATCTCATACTCAATGGCTTTATATGCCCTTGCATTGTTCTACGCGGCTTGCAGAGATCTACTTCGGCCATATAATCCTGTCCCAAAATTCATCATGATCAAATCAGTGGTGTTTCTCACATATTGGCAGGGCGTCCTGGTTTTCCTTGCTGCAAAATCTCGATTTATCAAGAATGCTGATAAGGCTGCTGATCTCCAGAACTTTGTGTTGTGTGTTGAGATGCTAATAGCAGCCGTTGGGCACTTATTTGCCTTCCCCTACAAGGAATATACAGGTCCCAATGCCCGCCCTTCACGTGGTTTCAGAGAAAGCCTTCTTCATGCTTTGAAATTCAATGATTTCTACCATGACACCGTTCATCAGTTTGCTCCTACATACAATGAATATGTGCTCTACAATCACAATGAGGGAGACAGTGCACAAACAAAGTATCCCTCGGGGAGCACCGCCACAAGTGGGCAGGGTGTAGAGTTGGCTGGCATCACCGTGGCGGCCTCAAACAGTCCAGTGTCGTCAAGTGTATCATCCAACCAGGCAGATCAGGAAGAAACAATGACAACCCCAATCAAGGACAAAGTTGATCCTCCTGGAGGGCTCTACGACCTCACAGAATTGCTTGATATTGATCTGTCTAGCTACCCAGCCAAGCTTCCTGGAACCACCGATGTAAGAAAACAATGATCAAGCTTGATGAGATGGGCTATTGGTAGGGTTGTTGCGATTGGGTTGGGGGAAAATCGTGATTATTATTTTTTTACTGTTGAAGAGTGCCATAGTTAACATTGTAAAAATGTGTGTATTATTTGTTCTGATTTTTCCCCCCGTTGAAGGGGGTTTATTCATTGTCAGCAGTTGCTGCCACACGGCCTCCCTCACCCTGCTCTTTATTAACCGTGTAAAATGTTGTGAGCTTAAGGTGAACCTTAGTGTCAAGGGGAGTCTATACCAGTACAATATTCTGCGTTTCTGGTGGCGTATTTTTTGTCTCTCTATCCAAGGGGCTTGTTTGGCCCTAGCCAAAATTTCTTCGTGCCTACAGCTTTGAAACATGAGCTCGGCACGCTGTCACCACAACAGGAACGTGA - >Zm00001eb211390_T001
CAGACGCGAAAAGCCGATGCTATCAACGCTAACTGTTAACCCCTCTCCGTTTGCCCAAGTGCCCAAGCCCAACCACCCGCACCAAGCCAAACCAGGACAGAGAGAGAGAGAGAGCACGCGGCGCGGCCCCGCCGAGCCGAGCGCCTGCCTGCAAGGCTCCCCTCCTCCCTTTCGCTTCCTCCTTCGATCGGCCCCGCCCAGCTGCTGCTGCTCGCGCCGCCGCGGTGAGACCCGGGAGGAGGGCCTGGTGGTGGGCGGCCCCGATGGAGTGGGCGTCGGCGGCGTACACGGCCGCGGCGCTGGTGTGCGCGGCGGCGGCGTGCGTGGTCGCGCTCGCGCACATCTACCGCCACCTCCTCCACTACGCCGAGCCAATCTACCAGCGGTTCATCGTCCGCATCATATTCATGGTCCCGGTATATGCTGTGATGTCATTCCTTTCCCTTATCCTCCCTAACAACGCGATATACTTTAATTCTATTCGGGAGATCTATGATGCTTGGGTCATCTACAATTTTCTCTCACTCTGCTTGGCATGGGTGGGAGGTCCTGGTGCTGTGGTGGCGTTTTATACGAAGATGCAAACAAGGTTGCTTGCAGTTTGTGATTCTCAAGCCTATTTTGGTTGTCATCACCTTCATACTTTACGCAAAAGGAAAATACAAAGATGGAAACTTCAGTGTCAACCAATCCTATCTCTACATAACTATCATATATACAATCTCATACTCAATGGCTTTATATGCCCTTGCATTGTTCTACGCGGCTTGCAGAGATCTACTTCGGCCATATAATCCTGTCCCAAAATTCATCATGATCAAATCAGTGGTGTTTCTCACATATTGGCAGGGCGTCCTGGTTTTCCTTGCTGCAAAATCTCGATTTATCAAGAATGCTGATAAGGCTGCTGATCTCCAGAACTTTGTGTTGTGTGTTGAGATGCTAATAGCAGCCGTTGGGCACTTATTTGCCTTCCCCTACAAGGAATATACAGGTCCCAATGCCCGCCCTTCACGTGGTTTCAGAGAAAGCCTTCTTCATGCTTTGAAATTCAATGATTTCTACCATGACACCGTTCATCAGTTTGCTCCTACATACAATGAATATGTGCTCTACAATCACAATGAGGGAGACAGTGCACAAACAAAGTATCCCTCGGGGAGCACCGCCACAAGTGGGCAGGGTGTAGAGTTGGCTGGCATCACCGTGGCGGCCTCAAACAGTCCAGTGTCGTCAAGTGTATCATCCAACCAGGCAGATCAGGAAGAAACAATGACAACCCCAATCAAGGACAAAGTTGATCCTCCTGGAGGGCTCTACGACCTCACAGAATTGCTTGATATTGATCTGTCTAGCTACCCAGCCAAGCTTCCTGGAACCACCGATGTAAGAAAACAATGATCAAGCTTGATGAGATGGGCTATTGGTAGGGTTGTTGCGATTGGGTTGGGGGAAAATCGTGATTATTATTTTTTTACTGTTGAAGAGTGCCATAGTTAACATTGTAAAAATGTGTGTATTATTTGTTCTGATTTTTCCCCCCGTTGAAGGGGGTTTATTCATTGTCAGCAGTTGCTGCCACACGGCCTCCCTCACCCTGCTCTTTATTAACCGTGTAAAATGTTGTGAGCTTAAGGTGAACCTTAGTGTCAAGGGGAGTCTATACCAGTACAATATTCTGCGTTTCTGGTGGCGTATTTTTTGTCTCTCTATCCAAGGGGCTTGTTTGGCCCTAGCCAAAATTTCTTCGTGCCTACAGCTTTGAAACATGAGCTCGGCACGCTGTCACCACAACAGGAACGTGA
CDS Sequence
- >Zm00001eb211390_T002
ATGATGCTTGGGTCATCTACAATTTTCTCTCACTCTGCTTGGCATGGGTGGGAGGTCCTGGTGCTGTGGTGGCGTTTTATACGAAGATGCAAACAAGGTTGCTTGCAGTTTGTGATTCTCAAGCCTATTTTGGTTGTCATCACCTTCATACTTTACGCAAAAGGAAAATACAAAGATGGAAACTTCAGTGTCAACCAATCCTATCTCTACATAACTATCATATATACAATCTCATACTCAATGGCTTTATATGCCCTTGCATTGTTCTACGCGGCTTGCAGAGATCTACTTCGGCCATATAATCCTGTCCCAAAATTCATCATGATCAAATCAGTGGTGTTTCTCACATATTGGCAGGGCGTCCTGGTTTTCCTTGCTGCAAAATCTCGATTTATCAAGAATGCTGATAAGGCTGCTGATCTCCAGAACTTTGTGTTGTGTGTTGAGATGCTAATAGCAGCCGTTGGGCACTTATTTGCCTTCCCCTACAAGGAATATACAGGTCCCAATGCCCGCCCTTCACGTGGTTTCAGAGAAAGCCTTCTTCATGCTTTGAAATTCAATGATTTCTACCATGACACCGTTCATCAGTTTGCTCCTACATACAATGAATATGTGCTCTACAATCACAATGAGGGAGACAGTGCACAAACAAAGTATCCCTCGGGGAGCACCGCCACAAGTGGGCAGGGTGTAGAGTTGGCTGGCATCACCGTGGCGGCCTCAAACAGTCCAGTGTCGTCAAGTGTATCATCCAACCAGGCAGATCAGGAAGAAACAATGACAACCCCAATCAAGGACAAAGTTGATCCTCCTGGAGGGCTCTACGACCTCACAGAATTGCTTGATATTGATCTGTCTAGCTACCCAGCCAAGCTTCCTGGAACCACCGATGTAAGAAAACAATGA - >Zm00001eb211390_T003
ATGATGCTTGGGTCATCTACAATTTTCTCTCACTCTGCTTGGCATGGGTGGGAGGTCCTGGTGCTGTGGTGGCGTTTTATACGAAGATGCAAACAAGGTTGCTTGCAGTTTGTGATTCTCAAGCCTATTTTGGTTGTCATCACCTTCATACTTTACGCAAAAGGAAAATACAAAGATGGAAACTTCAGTGTCAACCAATCCTATCTCTACATAACTATCATATATACAATCTCATACTCAATGGCTTTATATGCCCTTGCATTGTTCTACGCGGCTTGCAGAGATCTACTTCGGCCATATAATCCTGTCCCAAAATTCATCATGATCAAATCAGTGGTGTTTCTCACATATTGGCAGGGCGTCCTGGTTTTCCTTGCTGCAAAATCTCGATTTATCAAGAATGCTGATAAGGCTGCTGATCTCCAGAACTTTGTGTTGTGTGTTGAGATGCTAATAGCAGCCGTTGGGCACTTATTTGCCTTCCCCTACAAGGAATATACAGGTCCCAATGCCCGCCCTTCACGTGGTTTCAGAGAAAGCCTTCTTCATGCTTTGAAATTCAATGATTTCTACCATGACACCGTTCATCAGTTTGCTCCTACATACAATGAATATGTGCTCTACAATCACAATGAGGGAGACAGTGCACAAACAAAGTATCCCTCGGGGAGCACCGCCACAAGTGGGCAGGGTGTAGAGTTGGCTGGCATCACCGTGGCGGCCTCAAACAGTCCAGTGTCGTCAAGTGTATCATCCAACCAGGCAGATCAGGAAGAAACAATGACAACCCCAATCAAGGACAAAGTTGATCCTCCTGGAGGGCTCTACGACCTCACAGAATTGCTTGATATTGATCTGTCTAGCTACCCAGCCAAGCTTCCTGGAACCACCGATGTAAGAAAACAATGA - >Zm00001eb211390_T001
ATGATGCTTGGGTCATCTACAATTTTCTCTCACTCTGCTTGGCATGGGTGGGAGGTCCTGGTGCTGTGGTGGCGTTTTATACGAAGATGCAAACAAGGTTGCTTGCAGTTTGTGATTCTCAAGCCTATTTTGGTTGTCATCACCTTCATACTTTACGCAAAAGGAAAATACAAAGATGGAAACTTCAGTGTCAACCAATCCTATCTCTACATAACTATCATATATACAATCTCATACTCAATGGCTTTATATGCCCTTGCATTGTTCTACGCGGCTTGCAGAGATCTACTTCGGCCATATAATCCTGTCCCAAAATTCATCATGATCAAATCAGTGGTGTTTCTCACATATTGGCAGGGCGTCCTGGTTTTCCTTGCTGCAAAATCTCGATTTATCAAGAATGCTGATAAGGCTGCTGATCTCCAGAACTTTGTGTTGTGTGTTGAGATGCTAATAGCAGCCGTTGGGCACTTATTTGCCTTCCCCTACAAGGAATATACAGGTCCCAATGCCCGCCCTTCACGTGGTTTCAGAGAAAGCCTTCTTCATGCTTTGAAATTCAATGATTTCTACCATGACACCGTTCATCAGTTTGCTCCTACATACAATGAATATGTGCTCTACAATCACAATGAGGGAGACAGTGCACAAACAAAGTATCCCTCGGGGAGCACCGCCACAAGTGGGCAGGGTGTAGAGTTGGCTGGCATCACCGTGGCGGCCTCAAACAGTCCAGTGTCGTCAAGTGTATCATCCAACCAGGCAGATCAGGAAGAAACAATGACAACCCCAATCAAGGACAAAGTTGATCCTCCTGGAGGGCTCTACGACCTCACAGAATTGCTTGATATTGATCTGTCTAGCTACCCAGCCAAGCTTCCTGGAACCACCGATGTAAGAAAACAATGA
Protein Sequence
- >Zm00001eb211390_P002
MMLGSSTIFSHSAWHGWEVLVLWWRFIRRCKQGCLQFVILKPILVVITFILYAKGKYKDGNFSVNQSYLYITIIYTISYSMALYALALFYAACRDLLRPYNPVPKFIMIKSVVFLTYWQGVLVFLAAKSRFIKNADKAADLQNFVLCVEMLIAAVGHLFAFPYKEYTGPNARPSRGFRESLLHALKFNDFYHDTVHQFAPTYNEYVLYNHNEGDSAQTKYPSGSTATSGQGVELAGITVAASNSPVSSSVSSNQADQEETMTTPIKDKVDPPGGLYDLTELLDIDLSSYPAKLPGTTDVRKQ - >Zm00001eb211390_P003
MMLGSSTIFSHSAWHGWEVLVLWWRFIRRCKQGCLQFVILKPILVVITFILYAKGKYKDGNFSVNQSYLYITIIYTISYSMALYALALFYAACRDLLRPYNPVPKFIMIKSVVFLTYWQGVLVFLAAKSRFIKNADKAADLQNFVLCVEMLIAAVGHLFAFPYKEYTGPNARPSRGFRESLLHALKFNDFYHDTVHQFAPTYNEYVLYNHNEGDSAQTKYPSGSTATSGQGVELAGITVAASNSPVSSSVSSNQADQEETMTTPIKDKVDPPGGLYDLTELLDIDLSSYPAKLPGTTDVRKQ - >Zm00001eb211390_P001
MMLGSSTIFSHSAWHGWEVLVLWWRFIRRCKQGCLQFVILKPILVVITFILYAKGKYKDGNFSVNQSYLYITIIYTISYSMALYALALFYAACRDLLRPYNPVPKFIMIKSVVFLTYWQGVLVFLAAKSRFIKNADKAADLQNFVLCVEMLIAAVGHLFAFPYKEYTGPNARPSRGFRESLLHALKFNDFYHDTVHQFAPTYNEYVLYNHNEGDSAQTKYPSGSTATSGQGVELAGITVAASNSPVSSSVSSNQADQEETMTTPIKDKVDPPGGLYDLTELLDIDLSSYPAKLPGTTDVRKQ
Source: Genetic information comes from the article