Gene Details:

• Gene ID: Zm00001eb338190
• Gene Symbol: ZmGSK2 ZmSK1 gsk2
• Gene Name: glycogen synthase kinase2
• Genome: Zm-B73-REFERENCE-NAM-5.0
• Species: Zea mays

Functional Descriptions:

• ZmGSK2 was highly and ubiquitously expressed in maize tissues. Heterologous expression of ZmGSK2 carrying a point mutation in Arabidopsis resulted in a stunted growth phenotype, which could be partially rescued by bikinin, a strong activator of BR signaling. Growth responses of maize roots and aerial parts were affected when seedling roots were treated with epibrassinolide or bikinin.
• Our results suggest that ZmGSK2 is the ortholog of BIN2 and plays a critical role in mediating BR signaling. This study highlights the function of BR pathway key member in maize development and site-directed mutation of ZmGSK2 TREE domain, which extends a strategy to manipulate BR signaling in maize.
• In this study, we identified ZmGSK2 as the maize ortholog of BIN2 and point mutation of ZmGSK2 showed a bri1-like phenotype similar with other BR signaling mutants.
• ZmGSK2 is a candidate gene for drought tolerance,involved in BR biosynthesis.

Function-related keywords:

• growth ,  development ,  br ,  br-signaling ,  drought ,  seedling ,  tolerance ,  drought-tolerance ,  signaling-pathway-gene ,  seedling-growth

Literature:

• Zea mays GSK2 gene is involved in brassinosteroid signaling   DOI:  10.1007/s10725-022-00806-z ;  PMID:  
• Inhibition of the maize salt overly sensitive pathway by ZmSK3 and ZmSK4.   DOI:  10.1016/j.jgg.2023.04.010 ;  PMID:  37127254

Related News:

Gene Resources:

• NCBI ID: Zm00001eb074610
• UniProt accessions: A0A804QLC6

Sequences:

Source: Genetic information comes from the article