Gene Details:
- Gene ID: Zm00001eb058460
- Gene Symbol: ZmGLK44
- Gene Name: G2-like-transcription factor 44
- Genome: Zm-B73-REFERENCE-NAM-5.0
- Species: Zea mays
Functional Descriptions:
- Comprehensive genetic and molecular studies reveal the roles and mechanisms of two hub genes,ZmBx12 and ZmGLK44, in regulating maize metabolite biosynthesis and drought tolerance.
- ZmBx12 and ZmGLK44, for their role in regulating benzoxazinoids and tryptophan biosynthesis as well as maize drought tolerance via comprehensive genetic and molecular methods.
- We further verified two hub candidate genes,ZmBx12 and ZmGLK44, for their role in regulating benzoxazinoids and tryptophan biosynthesis as well as maize drought tolerance via comprehensive genetic and molecular methods. Our results provide novel insights into the genetic bases of metabolome-mediated drought adaptation in a crop.
- Based on our data sets, ZmGLK44 is a hub gene correlated / associated with 30 drought-responsive metabolites. Eight of these are annotated amino acids. To elucidate the roles of ZmGLK44 in regulating the biosynthesis of these drought-responsive metabolites, we generated ZmGLK44 inducible overexpression transgene maize lines.
Function-related keywords:
Literature:
- Genomic basis underlying the metabolome-mediated drought adaptation of maize. DOI: 10.1186/s13059-021-02481-1 ; PMID: 34488839
Related News:
Gene Resources:
- NCBI ID: LOC100282724
- UniProt accessions: B6TAS1
Sequences:
cDNA Sequence
- >Zm00001eb058460_T002
CGCGAGGGGTGCAGGCGCAAAACTACGCGTGTGGTGTGAGAAGCGGTAACTCGAGGCCGCGCCGATGGAGGGATCCCACGATTCACCGTGGAGTGTTGAGAGAGACAGAGACGTCCGGCTCCGGCCGCGACCGCGAGCTTATCGCGCTGGATGCGACGTGAGGAATCGGCAACGCAGCGCGCGCCCACCGCACCCCAGGCGCCGCGTGGTTTGGGGGCGTGGTCTCTCTCTCTCTCTCTCCTCCCATCCTGCGGTCCAGCTCGCAGATTCCATTCGCCCCGCTCGCCGCCACCACCCGTCTATACATATGCCAGGGCGGGCGCACCTCCGGAATCCAGATCCCCTCACAGTCATCCTCCACCCACCCCACCCACCGCCTCCGCCTCTCTCTCTTTCGTTTGTTCGTCTCGGCTTCCGGTCGCCGATTCTTCTCTGCGCAAAAGATTCCTGGTGGTGGTGCCCGTACCTTGCTCCACGCCTCGCTCGCGTCGCGTGCATGGGGCTGGACGTCGGCGGCATCGGGATGGGCCTGGATCTGGGTCTGGACCTCGGGCTGTTCGCCGCGCGGAGCGCCGGAGGGATGGCGGCCGCGGCCAAGGGTGCGCCGGCGGAGATCGAGTCCTGCATCAGGAGCCTCGAGGAGGAGCGCCGGAAGATCGAGGTGTTCAGGCGCGAGCTCCCGCTCTGCGTGCGTCTCCTCGCCGATGTGATCGACGAATTGAAGGATGAGGCCGCCAAGAGAGGCGGAGACGCGGAGGCCAAGGCCGACGACGGCGATAAGCGGAAATGGATGAGCACCGCTCAGCTGTGGCTCGACAGCGACGCCAAATCCGACGAGTCTGACAAAGAGCAACTGAGTGAAATCACTTCGCCGGAGCCCAAGTTGCTCGGTGGCGCACCCATGCCCATAAGGGCCGTTGCGGCGGTGCCACCCCTGCCGCCTCCATTCTTCAGGAGAGAAGACAGCTCTGCCGGCAGTGGTCTGTCGCTGGTACCACCCGCAGCTAAGCCGCCGATTCCTCCCATGTCTGCCAGCGACAACGCGAGCGGCAGATTCTGTGCCACTATGCCACCGTCTGGCTCTGGGGCCAACTTGCACTCTCAGGCTCAGCAGCAAGCCAGGAAGGCGAGGCGGTGCTGGTCGCCGGAGCTTCACCGGCTGTTTGTTGCCGCCTTGCATCAACTCGGCGGCCCTCAAGTTGCTACTCCGAAGCAGATCAGGGAGGTGATGAAGGTGGACGGGCTTACAAACGATGAAGTGAAAAGCCATCTCCAGAAGTACCGGCTGCACAACAGAAGATCCCCCGGCGTCGTGGCTCCGGTGAGCCAGTCGGTCATGCTGGCGGGCGGCCTCTGGGCTCCTCCTCATCAGGAGCAAAGCAGCTCGCAGTCCGGGTCTCCCCAGGGCCCGCTTCAGTTCTCTGGATCCGGTGTAGCGGCCACCGTCGGCGGCGATAGCAGCAGCAGCGACGAGGACGACAAGTCCGAAGGCTACAGCCGGAAATACGTGTAAAGGCCGCGTTCGACGGATGAGAGTGTAGAGATAGCGTCGCGGCTTCTGCTTGCCCGTCTGTGGCAATAACAGATTCATCAGTCTTGAGAGAGGTTGTAGTGCGTGCGCCCAAGAGCTCAACTGATCATGGGTTGGATTGTTTGTTTGTCATGTACGTACATGGAAAGCTGATGGCTTCCTGACTTTTAATTTCTGGGCAGGTCCCAAAATTTTCGCCCTGAGAATGAGATATTATATAGATAACATACATACATACCATATTCGTTGCCCGCCTGTTGTCTTGAATCGCGAATGGTTGCAGCGTTGTTGAATTGAATGAAATAAATACATGCCCTTGTCAGCGTCCCTG - >Zm00001eb058460_T001
CGCGAGGGGTGCAGGCGCAAAACTACGCGTGTGGTGTGAGAAGCGGTAACTCGAGGCCGCGCCGATGGAGGGATCCCACGATTCACCGTGGAGTGTTGAGAGAGACAGAGACGTCCGGCTCCGGCCGCGACCGCGAGCTTATCGCGCTGGATGCGACGTGAGGAATCGGCAACGCAGCGCGCGCCCACCGCACCCCAGGCGCCGCGTGGTTTGGGGGCGTGGTCTCTCTCTCTCTCTCTCCTCCCATCCTGCGGTCCAGCTCGCAGATTCCATTCGCCCCGCTCGCCGCCACCACCCGTCTATACATATGCCAGGGCGGGCGCACCTCCGGAATCCAGATCCCCTCACAGTCATCCTCCACCCACCCCACCCACCGCCTCCGCCTCTCTCTCTTTCGTTTGTTCGTCTCGGCTTCCGGTCGCCGATTCTTCTCTGCGCAAAAGATTCCTGGTGGTGGTGCCCGTACCTTGCTCCACGCCTCGCTCGCGTCGCGTGCATGGGGCTGGACGTCGGCGGCATCGGGATGGGCCTGGATCTGGGTCTGGACCTCGGGCTGTTCGCCGCGCGGAGCGCCGGAGGGATGGCGGCCGCGGCCAAGGGTGCGCCGGCGGAGATCGAGTCCTGCATCAGGAGCCTCGAGGAGGAGCGCCGGAAGATCGAGGTGTTCAGGCGCGAGCTCCCGCTCTGCGTGCGTCTCCTCGCCGATGTGATCGACGAATTGAAGGATGAGGCCGCCAAGAGAGGCGGAGACGCGGAGGCCAAGGCCGACGACGGCGATAAGCGGAAATGGATGAGCACCGCTCAGCTGTGGCTCGACAGCGACGCCAAATCCGACGAGTCTGACAAAGAGCAACTGAGTGAAATCACTTCGCCGGAGCCCAAGTTGCTCGGTGGCGCACCCATGCCCATAAGGGCCGTTGCGGCGGTGCCACCCCTGCCGCCTCCATTCTTCAGGAGAGAAGACAGCTCTGCCGGCAGTGGTCTGTCGCTGGTACCACCCGCAGCTAAGCCGCCGATTCCTCCCATGTCTGCCAGCGACAACGCGAGCGGCAGATTCTGTGCCACTATGCCACCGTCTGGCTCTGGGGCCAACTTGCACTCTCAGGCTCAGCAGCAAGCCAGGAAGGCGAGGCGGTGCTGGTCGCCGGAGCTTCACCGGCTGTTTGTTGCCGCCTTGCATCAACTCGGCGGCCCTCAAGTTGCTACTCCGAAGCAGATCAGGGAGGTGATGAAGGTGGACGGGCTTACAAACGATGAAGTGAAAAGCCATCTCCAGAAGTACCGGCTGCACAACAGAAGATCCCCCGGCGTCGTGGCTCCGGTGAGCCAGTCGGTCATGCTGGCGGGCGGCCTCTGGGCTCCTCCTCATCAGGAGCAAAGCAGCTCGCAGTCCGGGTCTCCCCAGGGCCCGCTTCAGTTCTCTGGATCCGGTGTAGCGGCCACCGTCGGCGGCGATAGCAGCAGCAGCGACGAGGACGACAAGTCCGAAGGCTACAGCCGGAAATACGTGTAAAGGCCGCGTTCGACGGATGAGAGTGTAGAGATAGCGTCGCGGCTTCTGCTTGCCCGTCTGTGGCAATAACAGATTCATCAGTCTTGAGAGAGGTTGTAGTGCGTGCGCCCAAGAGCTCAACTGATCATGGGTTGGATTGTTTGTTTGTCATGTACGTACATGGAAAGCTGATGGCTTCCTGACTTTTAATTTCTGGGCAGGTCCCAAAATTTTCGCCCTGAGAATGAGATATTATATAGATAACATACATACATACCATATTCGTTGCCCGCCTGTTGTCTTGAATCGCGAATGGTTGCAGCGTTGTTGAATTGAATGAAATAAATACATGCCCTTGTCAGCGTCCCTG
CDS Sequence
- >Zm00001eb058460_T002
ATGGGGCTGGACGTCGGCGGCATCGGGATGGGCCTGGATCTGGGTCTGGACCTCGGGCTGTTCGCCGCGCGGAGCGCCGGAGGGATGGCGGCCGCGGCCAAGGGTGCGCCGGCGGAGATCGAGTCCTGCATCAGGAGCCTCGAGGAGGAGCGCCGGAAGATCGAGGTGTTCAGGCGCGAGCTCCCGCTCTGCGTGCGTCTCCTCGCCGATGTGATCGACGAATTGAAGGATGAGGCCGCCAAGAGAGGCGGAGACGCGGAGGCCAAGGCCGACGACGGCGATAAGCGGAAATGGATGAGCACCGCTCAGCTGTGGCTCGACAGCGACGCCAAATCCGACGAGTCTGACAAAGAGCAACTGAGTGAAATCACTTCGCCGGAGCCCAAGTTGCTCGGTGGCGCACCCATGCCCATAAGGGCCGTTGCGGCGGTGCCACCCCTGCCGCCTCCATTCTTCAGGAGAGAAGACAGCTCTGCCGGCAGTGGTCTGTCGCTGGTACCACCCGCAGCTAAGCCGCCGATTCCTCCCATGTCTGCCAGCGACAACGCGAGCGGCAGATTCTGTGCCACTATGCCACCGTCTGGCTCTGGGGCCAACTTGCACTCTCAGGCTCAGCAGCAAGCCAGGAAGGCGAGGCGGTGCTGGTCGCCGGAGCTTCACCGGCTGTTTGTTGCCGCCTTGCATCAACTCGGCGGCCCTCAAGTTGCTACTCCGAAGCAGATCAGGGAGGTGATGAAGGTGGACGGGCTTACAAACGATGAAGTGAAAAGCCATCTCCAGAAGTACCGGCTGCACAACAGAAGATCCCCCGGCGTCGTGGCTCCGGTGAGCCAGTCGGTCATGCTGGCGGGCGGCCTCTGGGCTCCTCCTCATCAGGAGCAAAGCAGCTCGCAGTCCGGGTCTCCCCAGGGCCCGCTTCAGTTCTCTGGATCCGGTGTAGCGGCCACCGTCGGCGGCGATAGCAGCAGCAGCGACGAGGACGACAAGTCCGAAGGCTACAGCCGGAAATACGTGTAA - >Zm00001eb058460_T001
ATGGGGCTGGACGTCGGCGGCATCGGGATGGGCCTGGATCTGGGTCTGGACCTCGGGCTGTTCGCCGCGCGGAGCGCCGGAGGGATGGCGGCCGCGGCCAAGGGTGCGCCGGCGGAGATCGAGTCCTGCATCAGGAGCCTCGAGGAGGAGCGCCGGAAGATCGAGGTGTTCAGGCGCGAGCTCCCGCTCTGCGTGCGTCTCCTCGCCGATGTGATCGACGAATTGAAGGATGAGGCCGCCAAGAGAGGCGGAGACGCGGAGGCCAAGGCCGACGACGGCGATAAGCGGAAATGGATGAGCACCGCTCAGCTGTGGCTCGACAGCGACGCCAAATCCGACGAGTCTGACAAAGAGCAACTGAGTGAAATCACTTCGCCGGAGCCCAAGTTGCTCGGTGGCGCACCCATGCCCATAAGGGCCGTTGCGGCGGTGCCACCCCTGCCGCCTCCATTCTTCAGGAGAGAAGACAGCTCTGCCGGCAGTGGTCTGTCGCTGGTACCACCCGCAGCTAAGCCGCCGATTCCTCCCATGTCTGCCAGCGACAACGCGAGCGGCAGATTCTGTGCCACTATGCCACCGTCTGGCTCTGGGGCCAACTTGCACTCTCAGGCTCAGCAGCAAGCCAGGAAGGCGAGGCGGTGCTGGTCGCCGGAGCTTCACCGGCTGTTTGTTGCCGCCTTGCATCAACTCGGCGGCCCTCAAGTTGCTACTCCGAAGCAGATCAGGGAGGTGATGAAGGTGGACGGGCTTACAAACGATGAAGTGAAAAGCCATCTCCAGAAGTACCGGCTGCACAACAGAAGATCCCCCGGCGTCGTGGCTCCGGTGAGCCAGTCGGTCATGCTGGCGGGCGGCCTCTGGGCTCCTCCTCATCAGGAGCAAAGCAGCTCGCAGTCCGGGTCTCCCCAGGGCCCGCTTCAGTTCTCTGGATCCGGTGTAGCGGCCACCGTCGGCGGCGATAGCAGCAGCAGCGACGAGGACGACAAGTCCGAAGGCTACAGCCGGAAATACGTGTAA
Protein Sequence
- >Zm00001eb058460_P002
MGLDVGGIGMGLDLGLDLGLFAARSAGGMAAAAKGAPAEIESCIRSLEEERRKIEVFRRELPLCVRLLADVIDELKDEAAKRGGDAEAKADDGDKRKWMSTAQLWLDSDAKSDESDKEQLSEITSPEPKLLGGAPMPIRAVAAVPPLPPPFFRREDSSAGSGLSLVPPAAKPPIPPMSASDNASGRFCATMPPSGSGANLHSQAQQQARKARRCWSPELHRLFVAALHQLGGPQVATPKQIREVMKVDGLTNDEVKSHLQKYRLHNRRSPGVVAPVSQSVMLAGGLWAPPHQEQSSSQSGSPQGPLQFSGSGVAATVGGDSSSSDEDDKSEGYSRKYV - >Zm00001eb058460_P001
MGLDVGGIGMGLDLGLDLGLFAARSAGGMAAAAKGAPAEIESCIRSLEEERRKIEVFRRELPLCVRLLADVIDELKDEAAKRGGDAEAKADDGDKRKWMSTAQLWLDSDAKSDESDKEQLSEITSPEPKLLGGAPMPIRAVAAVPPLPPPFFRREDSSAGSGLSLVPPAAKPPIPPMSASDNASGRFCATMPPSGSGANLHSQAQQQARKARRCWSPELHRLFVAALHQLGGPQVATPKQIREVMKVDGLTNDEVKSHLQKYRLHNRRSPGVVAPVSQSVMLAGGLWAPPHQEQSSSQSGSPQGPLQFSGSGVAATVGGDSSSSDEDDKSEGYSRKYV
Source: Genetic information comes from the article