Gene Details:

• Gene ID: Zm00001eb379120
• Gene Symbol: ZmGAD5 d3
• Gene Name: dwarf plant3
• Genome: Zm-B73-REFERENCE-NAM-5.0
• Species: Zea mays

Functional Descriptions:

• ZmGAD5 functions in the regulation of maize growth, development, and morphogenesis.
• ZmGAD5 is a typical KAO protein, which likely functions in one step of GA biosynthesis.
• ZmGAD5 catalyzes the transformation of KA to GA12 in the GA biosynthesis pathway, and thus behaves as a typical KAO enzyme.
• Map-based gene cloning and allelic verification confirmed that ZmGAD5 encodes ent-kaurenoic acid oxidase (KAO), which catalyzes KA (ent-kaurenoic acid) to GA12 conversion during GA biosynthesis in maize. ZmGAD5 is localized to the endoplasmic reticulum and is present in multiple maize organs.
• In gad5-1, the expression of ZmGAD5 is severely reduced, and the levels of the direct substrate of KAO, KA, is increased, leading to a reduction in GA content.

Function-related keywords:

• growth ,  development ,  map-based-cloning ,  ga ,  ga-biosynthesis

Literature:

• GA Associated Dwarf 5 encodes an ent-kaurenoic acid oxidase required for maize gibberellin biosynthesis and morphogenesis   DOI:  10.1016/j.cj.2023.04.008 ;  PMID:  
• Hormonal regulation of inflorescence and intercalary meristems in grasses.   DOI:  10.1016/j.pbi.2023.102451 ;  PMID:  37739867
• Genome-wide dissection of changes in maize root system architecture during modern breeding.   DOI:  10.1038/s41477-022-01274-z ;  PMID:  36396706

Related News:

• The Crop Journal | 河南大学玉米生物学团队鉴定玉米GA生物合成途径中关键内根-贝壳杉烯酸氧化酶基因

Gene Resources:

• NCBI ID: 542580
• UniProt accessions: A0A1D6NWZ9 ,  A0A1D6NX00

Sequences:

Source: Genetic information comes from the article