Gene Details:

Functional Descriptions:

  • A peak GWAS signal revealed that natural variation in ZmFCL, encoding a 5-formyltetrahydrofolate cyclo-ligase, accounted for 30.12% of phenotypic variation in 5-FTHF content.
  • ZmFCL is significantly associated with 5-FTHF levels.
  • Haplotype analysis of ZmFCL revealed variable effects on 5-FTHF content.

Literature:

Gene Resources:

Sequences:

cDNA Sequence
  • >Zm00001eb219580_T001
    AAAAGCTATTATTTTAATTACTCGCCGCTTTCCTTCCCGATGCAGGGAGGTGCTTGCTGCTGATTTGAGTCCGAAAGCAGATAAGCCACATGCTGCATCCACAGACGGCCTTGGGACCCTTGCTAAATGGATTGGAAAACAAGAAAAAATCAAGCAGCAAGATACCCAGAGAGTTCCGTGCAAGTACACCTCATGATGCGCGCATCCCCGCTATAAGAGGGCCCTTTGCTCAATCACTGAGCAGGCACGCACTCACTCACTCAAGAGCCACGCACGCGCACTGACAGACACAGTCAGAGGGAGATCAGGGAAGAGAGGGGAGGGGAGGAGAGGAGGAAGAAGAAGAAGCAGCAGCAGCTGCAGCTGCAGGGCAGCAGGCATGGAGCCTCATCACGCAAACAAGCCAAGGCCAAAGCTCAGCGCGACGAAGCACTCCAAGTTCATCTCCTGCAAGCTCTACATTTCCGAATCCCGCAACGCTACGGCCGTGGACGCAGTGGAGCGTGCGAGCAAGAGTGACCCCCAGGTGGTCGTCGTCAGCCAGTTCGGGGACCATCACTACAACCGTTTCCGCTACACGCTTGTCTCCTACATCGTCGTCGTCGACGGCGGCGGATCGTCGGCGGCTGGAGAGGCGACAGTAGTACATAGCCCGATCAGGAAGGTGTTGCTGGCAATGATCGAGGCCGCGTTCTCAAGCATAGACCTGGAATCACAGTCGGGAGCGCATCCGAGGATCGGCGTAGTCGACGACCTGTCCTTCCACCCCGTGGGCCAAGCGACGATCGAGGACGCCGCTTCTCTGGCTAGGCAGGTAGCGTCTGACATTGCCTGCATCGCAGCAGTCCCAGTGTTCCTGTACGCAGCAGCCCACCCGGCGGGGAAGTCGGTGGGCGCGGTCCGGCGTGAGCTCGGCTACTACCGCCCAAACTACAGGGGCAACCAGTGGTCAGGCAGCGTGCTCCCCAACGTCCTGCCGGTGAAGCCTGACGTCGGTCCGGCCCACGTCGTCTCGCACAAGAGAGGCGCTACGACGGTGGGTGTCACGCCTTGGATCGAGAACTACAATGTCCCCGTGCTGTGTAAGGACGTCGCCACCGTCAGGAGGATCACCCGTGGTGTCACTGGACGGAGCGGAGGCCTTCCCACGGTGCAGGCTCTCGCGCTCTTCCATGGAGATGACTGCACCGAGATTGCGTGCTTGCTGGATCCAGATCATGCCAGCGCCTATCAAGTTCAGACCGTCGTGGAACAGATTGCAGGAGACCAGGGACTTGAGGTTGAGCAGGGATACTACACTGACATAACCAAGGACGAAGCGCTCGATAAGTATCTCAAGATTGCTTGCGCTGACGACTGATGAGCTTGTAGAAATAAATACATGGGGTAAATGTAAACTCATGTTTGTAGCACTGATGCTGCTGCTGGAGCATTATTTTTTTTGCCCGTGTAAATTCAAATTTGCATCTGAAAACTTGAGTTTGGATCTGAGCTCTTTTCAGAGAAGAAAACAAATGCATCATCAGTTTTATTCTGAAGAATGTTACCGTTTTCCTCCAGATGGATGAAGAGATGAGATCCATGCCGCAACGACTTCCTCTTTTCCCAAATGTTGAAGAACTCTGAACACAGGCTAAGAAACCTCTTTTCCCAAATTTTGAAGAACTTATTATTTGCTGGTATTAGGGGAAAAAAGATCTTTGCGAGTGGGTATGAGTACAACCCTTGACAATGTAAGTATATATTTTTTTCCTAAAAGGTTGAGTGAGATCATCATTACAATTTTATTATTTGTATTAGGGCTCAAATACTGGTAAGAAAAATTCTGAAGATTTACAGTACACCAACGCTACTCTACATATGTATGTTGATCTACAGACACTTCAAACTATGAACAAAACACACGCCGTGCTATATATACACACACGGTTCGTCAAAATGCTG
CDS Sequence
  • >Zm00001eb219580_T001
    ATGGAGCCTCATCACGCAAACAAGCCAAGGCCAAAGCTCAGCGCGACGAAGCACTCCAAGTTCATCTCCTGCAAGCTCTACATTTCCGAATCCCGCAACGCTACGGCCGTGGACGCAGTGGAGCGTGCGAGCAAGAGTGACCCCCAGGTGGTCGTCGTCAGCCAGTTCGGGGACCATCACTACAACCGTTTCCGCTACACGCTTGTCTCCTACATCGTCGTCGTCGACGGCGGCGGATCGTCGGCGGCTGGAGAGGCGACAGTAGTACATAGCCCGATCAGGAAGGTGTTGCTGGCAATGATCGAGGCCGCGTTCTCAAGCATAGACCTGGAATCACAGTCGGGAGCGCATCCGAGGATCGGCGTAGTCGACGACCTGTCCTTCCACCCCGTGGGCCAAGCGACGATCGAGGACGCCGCTTCTCTGGCTAGGCAGGTAGCGTCTGACATTGCCTGCATCGCAGCAGTCCCAGTGTTCCTGTACGCAGCAGCCCACCCGGCGGGGAAGTCGGTGGGCGCGGTCCGGCGTGAGCTCGGCTACTACCGCCCAAACTACAGGGGCAACCAGTGGTCAGGCAGCGTGCTCCCCAACGTCCTGCCGGTGAAGCCTGACGTCGGTCCGGCCCACGTCGTCTCGCACAAGAGAGGCGCTACGACGGTGGGTGTCACGCCTTGGATCGAGAACTACAATGTCCCCGTGCTGTGTAAGGACGTCGCCACCGTCAGGAGGATCACCCGTGGTGTCACTGGACGGAGCGGAGGCCTTCCCACGGTGCAGGCTCTCGCGCTCTTCCATGGAGATGACTGCACCGAGATTGCGTGCTTGCTGGATCCAGATCATGCCAGCGCCTATCAAGTTCAGACCGTCGTGGAACAGATTGCAGGAGACCAGGGACTTGAGGTTGAGCAGGGATACTACACTGACATAACCAAGGACGAAGCGCTCGATAAGTATCTCAAGATTGCTTGCGCTGACGACTGA
Protein Sequence
  • >Zm00001eb219580_P001
    MEPHHANKPRPKLSATKHSKFISCKLYISESRNATAVDAVERASKSDPQVVVVSQFGDHHYNRFRYTLVSYIVVVDGGGSSAAGEATVVHSPIRKVLLAMIEAAFSSIDLESQSGAHPRIGVVDDLSFHPVGQATIEDAASLARQVASDIACIAAVPVFLYAAAHPAGKSVGAVRRELGYYRPNYRGNQWSGSVLPNVLPVKPDVGPAHVVSHKRGATTVGVTPWIENYNVPVLCKDVATVRRITRGVTGRSGGLPTVQALALFHGDDCTEIACLLDPDHASAYQVQTVVEQIAGDQGLEVEQGYYTDITKDEALDKYLKIACADD

Source: Genetic information comes from the article