Gene Details:

Functional Descriptions:

  • ZmCM2 is predicted to function in the production of prephenate from chorismate that is also a precursor for salicylic acid (SA). Interaction of Vag2 with ZmCM2 may alter the SA level in the host. Although no significant differences in SA level of wild-type and vag2 deletion mutant-colonized leaves and ears could be observed, expression of the SA indicator genes PR1 and PR5 was induced in tissues colonized with vag2 deletion strains.
  • We identified the cytoplasmic maize chorismate mutase ZmCM2 by yeast two-hybrid screening as a possible interaction partner of Vag2.
  • The binding of Vag2 to ZmCM2 inhibits the back reaction of the ZmCM2-catalyzed interconversion of chorismate and prephenate, thus contributing to fungal virulence by lowering the plant SA-induced defenses.

Literature:

Gene Resources:

Sequences:

cDNA Sequence
  • >Zm00001eb234080_T001
    ACTCCGACCATTTCCACCAACGGTCTGGACGGGTGGACTGACCACAAGTCGCCGACTCGCCATCCGCGTCAACACCACTGCAACCACCACCGCCGTGTGGGAGGCCCAAACCACGCGCCTTTCCCCACTGCACCAGGCAACCCACCAGCAGGCCGCAGTTCACGCTTGGCTGACGACCGACCCCCATTCGTTCTAGCCCTCCCTCCGACACTCCGATCCATTACTCGCTATGGACGCGGCGGGCGGCGACCAGCTAAGCCTGGCCGCGGTGCGCGACGCGCTGGTGCGGCTGGAGGACTCCGTGGTGTTCGCGCTCATCGAGCGCGCCCGGCATCCGCGGAACGCGCCAGCCTACGCGCCCGCCGCCACCGCTGGAGAACATTCGCTCGTGGAGTTCTTCGTCCGGGAAGCAGAGGCCCTCAACGCAAAGGCTGGACATTATCAAAAGCCAGAAGATGTTCCATTCTTCCCTCAAGATCTACCCTCACCTCTCTTTCCTACAAAGCCTTCCCCAAAGGTCTTGCACCCTTTTGCTTCATTGGTCACCGTGAATGATGCAATATGGAAAATGTATTTTGATGAATTGCTCCCGTTATTCACTGTTGATGGTGATGATGGCAGCTATGCACAAACAGTTGCACTGGATTTAGCGTGTCTGCAGGTTCTATCACAAAGAATTCATATTGGTAAATATGTTGCTGAGGTGAAGTTCAAAGACGCTCCTCAAGAATATAGTCGACTAATAAAAGAAAAGGACAGCAATTCTCTGATGGATATGCTGACATTCAAGGCTGTGGAAGAGAAGGTCAAGAAGAGAGTAGAGAAGAAGGCTAGGACGTTCGGGCAGAACGTCACCTTGGATGACAATGCCACTGCTGGTGACAGCGAGTGCAAGGTCGATCCCAAAGTGCTCTCCAAGCTGTATGATCAGTGGGTGATGCCACTGACCAAGGATGTCGAAGTCGAGTATCTCCTGCGCCGCCTCGACTGATCAGTGATCACCCGATTAGCTGTAGCTGCGAACTTTATGTACGCGTGGGTTTCAGTTTGCTTTGCACATGCCCTTTATGGCTTTATCGTTCAAACTCAACTACGAGAGAACGTTACCAGGATCTGGCCTTCGTCTTTGTCAGCCTGCTTGCCCGTCATCTGCATGAGTAGTCCAACTGTAAGTGACGCTTGGTATGGAATGTAAGAAAAGTAATACAACTGGTTACATGTTATCTTTAATCTCCTGTTGTTCGTCTGTAAGTGACTGGCAACACAGTAGGGTACCAATTCTCTGGTTCAGAAACGTATTATGTTTCTTGCTTACGTGACAAATACCAAACAAAATAGTTACAGCTTTGAC
CDS Sequence
  • >Zm00001eb234080_T001
    ATGGACGCGGCGGGCGGCGACCAGCTAAGCCTGGCCGCGGTGCGCGACGCGCTGGTGCGGCTGGAGGACTCCGTGGTGTTCGCGCTCATCGAGCGCGCCCGGCATCCGCGGAACGCGCCAGCCTACGCGCCCGCCGCCACCGCTGGAGAACATTCGCTCGTGGAGTTCTTCGTCCGGGAAGCAGAGGCCCTCAACGCAAAGGCTGGACATTATCAAAAGCCAGAAGATGTTCCATTCTTCCCTCAAGATCTACCCTCACCTCTCTTTCCTACAAAGCCTTCCCCAAAGGTCTTGCACCCTTTTGCTTCATTGGTCACCGTGAATGATGCAATATGGAAAATGTATTTTGATGAATTGCTCCCGTTATTCACTGTTGATGGTGATGATGGCAGCTATGCACAAACAGTTGCACTGGATTTAGCGTGTCTGCAGGTTCTATCACAAAGAATTCATATTGGTAAATATGTTGCTGAGGTGAAGTTCAAAGACGCTCCTCAAGAATATAGTCGACTAATAAAAGAAAAGGACAGCAATTCTCTGATGGATATGCTGACATTCAAGGCTGTGGAAGAGAAGGTCAAGAAGAGAGTAGAGAAGAAGGCTAGGACGTTCGGGCAGAACGTCACCTTGGATGACAATGCCACTGCTGGTGACAGCGAGTGCAAGGTCGATCCCAAAGTGCTCTCCAAGCTGTATGATCAGTGGGTGATGCCACTGACCAAGGATGTCGAAGTCGAGTATCTCCTGCGCCGCCTCGACTGA
Protein Sequence
  • >Zm00001eb234080_P001
    MDAAGGDQLSLAAVRDALVRLEDSVVFALIERARHPRNAPAYAPAATAGEHSLVEFFVREAEALNAKAGHYQKPEDVPFFPQDLPSPLFPTKPSPKVLHPFASLVTVNDAIWKMYFDELLPLFTVDGDDGSYAQTVALDLACLQVLSQRIHIGKYVAEVKFKDAPQEYSRLIKEKDSNSLMDMLTFKAVEEKVKKRVEKKARTFGQNVTLDDNATAGDSECKVDPKVLSKLYDQWVMPLTKDVEVEYLLRRLD

Source: Genetic information comes from the article