Gene Details:

• Gene ID: Zm00001eb228310
• Gene Symbol: ZmATR
• Gene Name: ataxia-telangiectasia mutated and RAD3-related1
• Genome: Zm-B73-REFERENCE-NAM-5.0
• Species: Zea mays

Functional Descriptions:

• We selected two independent CRISPR/Cas9-induced mutant lines for both genes, named ATR-A and ATR-B, representing ZmATR mutants, and ATM-A and ATM-B, representing Zmatm mutants.
• Both ZmATR lines showed a reduction of root length between 40% and 50% compared with the untreated plants, whereas WT plants did not show a significant reduction of root growth.
• Conserved role of ZmATR in the response to replicative stress.
• ZmATR plays a conserved role in the replicative stress response.
• ZmATR plays a predominant role in the response to DSBs, whereas ZmATM shows a minor role.

Function-related keywords:

• root ,  growth ,  stress ,  root-growth ,  stress-response ,  root-length

Literature:

• Maize ATR safeguards genome stability during kernel development to prevent early endosperm endocycle onset and cell death.   DOI:  10.1093/plcell/koab158 ;  PMID:  34086963
• Comparison of meiotic transcriptomes of three maize inbreds with different origins reveals differences in cell cycle and recombination.   DOI:  10.1186/s12864-022-08922-w ;  PMID:  36224518

Related News:

• The Plant Cell | 玉米DNA损伤响应依赖激酶ATR在影响胚发育和细胞死亡过程中的关键作用

Gene Resources:

• NCBI ID: 103626462
• UniProt accessions: A0A1D6GWH9 ,  A0A1D6GWI1 ,  A0A1D6GWI2

Sequences:

Source: Genetic information comes from the article