Gene Details:

Functional Descriptions:

  • Maize HEAT UP-REGULATED GENE 1 (ZmHUG1) plays vital roles in heat stress tolerance.
  • ZmHUG1 encodes a heat-inducible holdase-type molecular chaperone localized in the ER. Knockout mutant of ZmHUG1 exhibited remarkably enhanced sensitivity to heat stress.
  • The ZmHUG1 mutant showed severe ER stress under high temperature. MAIZE PRENYLATED RAB ACCEPTOR 1.C1 (ZmPRA1.C1) was identified as a client of ZmHUG1, and heat-induced aggregation of ZmPRA1.C1 was accelerated in the ZmHUG1 mutant.
  • The expression of ZmHUG1 was rapidly transactivated by ER stress sensor BASIC LEUCINE ZIPPER DOMAIN 60 (bZIP60) when heat stress occurred. This study reveals a ZmHUG1-based thermo-protective mechanism in maize.

Literature:

Gene Resources:

Orthologs:

Sequences:

cDNA Sequence
  • >Zm00001eb376850_T001
    CTCCGATCACGTGGCGTGGACAAACGGACGGCGCAGAACTTCCCCGCCACATAGGCACGCGCGCCAGCCCGAACCGAACCAAACCAGCCCTGACCATTTCAGTTCGGCTGCTGCAAGAACCGAACAGAGCAGCTGCGACGAGCCCAACCAGTGAGGGGGAGAGATGGCCCGTCGCGCCGTCGCCTTGCTCGTCGCCGTCGCGCTCGCGACCGTGCTCCTGCATACGGCGGAGGTTGCGGCGGGGCAGAAGAAGCCGGCGACGGCCGCGAGGCGGGAGGACATCCCCTACATCCGGTGCCAGGTGTGCGAGCGGATCGCGCGCGAGATCTCCGCGCAGGTCGCCAAGAAGCACCAGGCTCTCCCGCCCTCCAAGAAGGTACCGGAGATCGAGATCATCGAGGTCGCGGAGAATGTCTGCAACCTAAAGAAGCAGGAGGCGGATTGGATGCTTCGGATCGATATCGTCGAGAAAGGCGACAAGCTCGAGCTTGTTGAGCAAGATGAGGAAGGGCATTGCAATGCAGAATGCAAGACCATTGAGCGTGCATGTCAGGAGGTGATAGGATATGCTGATACCGATGTTGCTGAGTTTGTATACAAAAATAACCCCTCGGTCGATCAGCTTATGAAATTTCTCTGCAAAGATCTTTCGAAAGCATGTGCCAAGGACCCACCGCCAGTTCCAAAAGATCGTGTCCCTGGGGAACCATTTGCAAGGAAGCCATCAAAGGATGCTGAGATGGAAAAGATATTGAGATCAATGGAGGGTATGCCGGGAGCCCCAAGCATGAAAATGTACTCCAGGGACGATCTGATGAAAAATAACTTTGGTACTGAAGACGACGACGAGGAGGATGATGAAGATGAGGATGACAACTTCCCAAAGAACTTGGGGAAAGCTCTGAAAAACAAGGGCTCTCAAAAGAAAGATTTGAAACAGCAAGTCGTGCAGCAGTTCAAGGATACCAGCAAGAAGTTGAAAGGGCATGTAAACAAGGTGTCCGGTATGGTAAAGAAATGGTGGAAAGGGGCAAAGAAGCCTGCCAAATCCAGCAAAAGCAAAACTGAGCTCTGAAGCATTGTTGAATCACGTCAGTAAATCTCATCCGTCTTCCACTTCTCCTGGAGCAAAGTTTTAGATGGTTATCGGAAGATAAAAGTTACAGCAACGCAACCAGGGCTTTTGTTAGAGAGTTTAGCTACATAAAACGTGTACAATTGTTTGTTTTTAACTTCTGTTATTTGCAGTGTACACTAGTAAAAGAACTGAACTCCGATGATAGTTTTTTTCCAGATTAGTCGTGTCCCAATTGGTCGTTATAGTGTTTGATACTCTATAAAACTAAACAGCTGGTGACGCCAGGGAATTAGTTTATTGGCTATGCATAATCGAACTTTTCACTAATTAATGACTTGCTGTC
CDS Sequence
  • >Zm00001eb376850_T001
    ATGGCCCGTCGCGCCGTCGCCTTGCTCGTCGCCGTCGCGCTCGCGACCGTGCTCCTGCATACGGCGGAGGTTGCGGCGGGGCAGAAGAAGCCGGCGACGGCCGCGAGGCGGGAGGACATCCCCTACATCCGGTGCCAGGTGTGCGAGCGGATCGCGCGCGAGATCTCCGCGCAGGTCGCCAAGAAGCACCAGGCTCTCCCGCCCTCCAAGAAGGTACCGGAGATCGAGATCATCGAGGTCGCGGAGAATGTCTGCAACCTAAAGAAGCAGGAGGCGGATTGGATGCTTCGGATCGATATCGTCGAGAAAGGCGACAAGCTCGAGCTTGTTGAGCAAGATGAGGAAGGGCATTGCAATGCAGAATGCAAGACCATTGAGCGTGCATGTCAGGAGGTGATAGGATATGCTGATACCGATGTTGCTGAGTTTGTATACAAAAATAACCCCTCGGTCGATCAGCTTATGAAATTTCTCTGCAAAGATCTTTCGAAAGCATGTGCCAAGGACCCACCGCCAGTTCCAAAAGATCGTGTCCCTGGGGAACCATTTGCAAGGAAGCCATCAAAGGATGCTGAGATGGAAAAGATATTGAGATCAATGGAGGGTATGCCGGGAGCCCCAAGCATGAAAATGTACTCCAGGGACGATCTGATGAAAAATAACTTTGGTACTGAAGACGACGACGAGGAGGATGATGAAGATGAGGATGACAACTTCCCAAAGAACTTGGGGAAAGCTCTGAAAAACAAGGGCTCTCAAAAGAAAGATTTGAAACAGCAAGTCGTGCAGCAGTTCAAGGATACCAGCAAGAAGTTGAAAGGGCATGTAAACAAGGTGTCCGGTATGGTAAAGAAATGGTGGAAAGGGGCAAAGAAGCCTGCCAAATCCAGCAAAAGCAAAACTGAGCTCTGA
Protein Sequence
  • >Zm00001eb376850_P001
    MARRAVALLVAVALATVLLHTAEVAAGQKKPATAARREDIPYIRCQVCERIAREISAQVAKKHQALPPSKKVPEIEIIEVAENVCNLKKQEADWMLRIDIVEKGDKLELVEQDEEGHCNAECKTIERACQEVIGYADTDVAEFVYKNNPSVDQLMKFLCKDLSKACAKDPPPVPKDRVPGEPFARKPSKDAEMEKILRSMEGMPGAPSMKMYSRDDLMKNNFGTEDDDEEDDEDEDDNFPKNLGKALKNKGSQKKDLKQQVVQQFKDTSKKLKGHVNKVSGMVKKWWKGAKKPAKSSKSKTEL

Source: Genetic information comes from the article