Gene Details:

• Gene ID: Zm00001eb298370
• Gene Symbol: DEK58
• Gene Name: defective kernel58
• Genome: Zm-B73-REFERENCE-NAM-5.0
• Species: Zea mays

Functional Descriptions:

• DEK58 encodes an Rrp15p domain-containing protein with 15.3% identity to yeast Rrp15. Over-expression of DEK58 rescues the mutant phenotype.
• DEK58 is localized in the nucleolus. Ribosome profiling and RNA gel blot analyses show that the absence of DEK58 reduces ribosome assembly and impedes pre-rRNA processing, accompanied by the accumulation of nearly all the pre-rRNA processing intermediates and the production of an aberrant processing product P-25S*.
• DEK58 is essential to seed development in maize. It functions in the early stage of pre-rRNA processing in ribosome biogenesis, possibly through interacting with ZmSSF1 and ZmCK2α in maize.
• This event occurs during the pre-90S stage, as 35S serves as a diagnostic intermediate for this early processome, implying that DEK58 plays a role in the early stage of pre-rRNA processing in maize.

Function-related keywords:

• development ,  seed ,  seed-development ,  seed-phenotype ,  protein

Literature:

• Defective kernel 58 encodes an Rrp15p domain-containing protein essential to ribosome biogenesis and seed development in maize.   DOI:  10.1111/nph.19460 ;  PMID:  38058237

Related News:

Gene Resources:

• NCBI ID: LOC100280074
• UniProt accessions: B4FYQ9

Orthologs:

Sequences:

Source: Genetic information comes from the article