Gene Details:
- Gene ID: Zm00001eb153890
- Gene Symbol: PCW1|ppr199
- Gene Name: DYW domain-containing protein 1
- Genome: Zm-B73-REFERENCE-NAM-5.0
- Species: Zea mays
Functional Descriptions:
- Maize PPR-E proteins mediate RNA C-to-U editing in mitochondria by recruiting the trans deaminase PCW1|ppr199.
- Report that pentatricopeptide repeat (PPR)-E subclass proteins carry out RNA C-to-U editing by recruiting the trans deaminase PPR motifs, coiled-coil, and DYW domain-containing protein 1 (PCW1|ppr199) in maize (Zea mays) mitochondria
- Loss-of-function of bZIP and coiled-coil domain-containing PPR 1 (bCCP1) or PCW1|ppr199 arrests seed development in maize. bCCP1 encodes a bZIP and coiled-coil domain-containing PPR protein, and PCW1|ppr199 encodes an atypical PPR–DYW protein.
- The PCW1|ppr199-mediated editing sites are exclusively associated with PPR-E proteins. bCCP1 interacts with PCW1|ppr199 and the PPR-E protein Empty pericarp7 (EMP7).
- These results suggest that PPR-E proteins function in RNA editing by recruiting the trans deaminase PCW1|ppr199 and bCCP1, and MORF1/8 assist this recruitment through protein–protein interactions.
Function-related keywords:
Literature:
- Maize PPR-E proteins mediate RNA C-to-U editing in mitochondria by recruiting the trans deaminase PCW1. DOI: 10.1093/plcell/koac298 ; PMID: 36200865
Related News:
Gene Resources:
- NCBI ID: LOC103651234
- UniProt accessions: A0A1D6ND84
Orthologs:
Sequences:
cDNA Sequence
- >Zm00001eb153890_T001
GGCTGGTCCCATATGCCTCAGCCCAGGCGTCAGATACTCGATATGCTGATCACGCCACAGCTCTAGCCTGCACAGAAAACAACTCGACAACAAAAGGCTGATGAGGAGACAGTGGACCCACACCCTAATATCAACTCACATTCAAGTGTTTGTGTCTAAGACGCTATCCAACAATACATAACTAGCAGTACTAAGCTTCTGTACGCACCAAATCAGAAACCCTGCACTGAACTATCTGGTGCCACGGGCAAAGTTATCAGAGGACTAGCTATTTTTCAAGCTACAGCGTATCAAATACTCCAATATCCAAACTAAATCCATGCGTTGAGACCCGCCAAGCACTGCCGGCTGTCGGCAGCCAGGGGATATACTCAAATAGAAGTGAGAAAACTAGCGTGTGCTTAGGGATGCTCACATGATGGATTTCGTGTTGGGCGCGGCCCCGAAGAGGGAGCGGTAGATGTCGCCAACCCTGGCCTCCACCTTCATCTGCTCCACCTGCGTCACCGTGAGCCTCGGTAGGTCGGGATCCGCCGCCGCTGCCGGGTCGTCTCCGGTGGGCGGCGTCGACTGCGGGGAGGGGTCCATGGACGCAGCGGCCTGGTGTGGAGTCGGAGGCGGAGCGCCGCCGCCTGGCTGCGCTCTCGAGTGCTGCGGCCTGCGGTTTCGGCAGTGCTGCCCTTGCTGTTGCGGCCTTGCGGGGTCCGGTTCTCGGCTGCTTCGGTGTTGTGGTGAGACGGGTGAGCGGAGCAATCTTACGATGCCGCGAGACGGGTGAGCCCAACCAATAATTTCATTGAGCCGGCCCAATCACACTGACCAGAGCTATGTTATCCAACCCGATACCACACCAAACCCACGACGGCACCGCAGCAACCCATTCCATAGCCACGCGAGTGACGCGACGCGACGCACGGCCTGCCTGAGGCAGCGCATCTGCTTGGCGGCCGGGAGCAGCCGCCGCTTCGCCTTCGTGAGGGTTTAAGCGACGAAGAGAAAGGGGAGGAAGCGAGCCCCCAGGGAGGTGCAGAGGGAGAGGGTGGGAGATGGCTGCAATGGTTGGAGCGCGTAGGGCGCTCTTGGCCGCTCGGTTCTCTCCTCGCGGCACCATCGCGGCGTCGGCCGCGCCAGCTCCCCTCTACCGGCCCATGGATTCGCCACTCAGGCTTCCAGCTGAAAGAGTTTGTCTACAGTCTTGGGTTCCACATCGAGGGGCTGGTACCTTTGCATCTGAAAGGACTGATGAAGATTATCAGCGTGAGTGGGGACAAAACAAAGCAGGTAGCTACACTGACTCCCGTTGGAACGGCTCTAATCTCCAACTTCAGAGAGATGTCACTTCAGCTGGTTCCACAACAGGTACTCACAAAAATAAGGGTGTGGATGGTGTTGGTGGCAGTTCTGAGCAACATTACAGAAGTGGTGGATCATATGGCTTTCAAAACAATCATCAGCCATATACTGGTACAAGAGCGAATAATGAGAGATACAATGCATCACAACCTTATAGAGGTAGTGGTCCATACAGCCAGCAAGGCCTTGATGGACATTTTTCAAATGATCGTCAACAGTACAATGGCACAGAAGCTAATAGTACATATAGCTCTGGATACTACACCCAAAGTAAGCAGAAGATTTATGAAGGAGAGGGAGCTAATAATGGGCAGTATGGATATGGTCCTTCAGGACAACCATGTCCGAACCCAGTTGGAAATAGCCAGCGAGTTCAGAAACAGCAATATGTTGATCATAGATCTGGGGGAAGTTATCCAGATAGATCTGGGCATCATCCCTCTCAATATGTAAATCCAACTCATTCCCGTAAGGAGCATGTTGCAGGGTTTCAGCAAGGCAACAATAGTAATTTTGGATATAATGCTTCGCAGGCATATCAAAGCCCTTATTTCACTAGGCAGGCTGATACACATAGTACTTCTCAAGGATATTCCATGTACCTAAATACAGATGTGCAACGCCTCTCTCATGGAGTTCATCAAGAAAAACATTCACATGCACAATCTGCTGGATCATTTGGGAACCATGTAAATAGTGCACCTCATGAATATGGCAAATATCATCAGTCACTACAAGGCAACCCTTCAAATGTTGGATCGCCTTACGAAGTACCTAGTGAAGCTGGCAGCAAACACAAATGTACTGTTGAAGAACTGGAGAAGTTTTGTGATGATGGCAATGTAAAAGAAGCTCTGGAAGTTTTGGCTATGCTAAAGGAAAACAGAATTGTGCTACATGCTCCTCAGTACTTCAGATTGATGCAAGCATGTGGTGATGCAACTGCCCTTTCAGAAGCAAGATTAATACATAGTCAAATATCTGAATCATCACTTACTGTTGACACAGATTTTCAAAACAAAATTATGGAGATGTATGCTAGGTGTGGTTCTATGGAAGATGCAAAGAAGATTTTCAGTTCTATGGATCATCATAATTTGACTTCTTGGAACACTATGATCTCAGGTTTTGTGCACAATGTTCTTGGTGAAGAAGCAATAGATTTTTTTGAACGGTTTAAGCAGACAGGGGACAAGCCAGATCATGGCATGTTCAGACATGTTTTCTTGGCATGTGGAATTTTGGGATCTGTTAATGAAGGAATGTTGCATTTTGAATCCATGCAGAAAGATTTTGGCATACATCCCACTACAGAGCATTATGCAAGCATTGTTACTATGCTTGGACAGTCTGGCTACATTGTCGAGGCTTATGAATTCGTGGAACGGATGCCTGTGGAACCAAGCATTGAGGTATGGGAAAATTTGATGAACATGTGTCGACTTAATGGCTTTTTAGAGCTTGGAGATCGTTGTGCTCAGATCATAGAGTGCTTGGATTCTTCTAGGCTGAATGAACAGTCTAAAATGGGTCTGTTCCCTGTCGATGTGTCAGATCTTGCAAAGGAAAAGGAAAGGAAAAAGGCAAGTGTCGCCGAAGCTCGGAGCAAGGTCCATGAATACAGAGCTGGCGACCGATCTCACCCTGACACTCCTAAGATCTATGAAGAGCTGAGGTATTTGTTGGCTCACATGAAGGAAGCTGGGTATATTGCTGACACTCGATTTGTTCTTCACGATGTTGATCAAGAAACCAAAGAGGATGCTTTACTGGCTCACAGTGAGAGGCTGGCTATCAGTTACGGTCTTATAACAAGTGCTCCCCGCTCACCTATTCGGGTTATAAAGAATCTTCGATCCTGTGGGGATTGTCACACGGCTTTCAAGATAATCTCAAAACTTGTTGGACGTCAGATCATTGCAAGGGATGCAAAGAGGTTCCACCACTTCGAAAATGGTGTGTGTTCTTGCAAAGACTACTGGTAAACAAGATGAAAGAAAGTCCACATCTTGGTCAATTTTTATTGGCACAAGACCGCTATAGGTTGTTTATGTGCTGAAGGTAGGCTGATGCCTATCTAACATTTAGTTAGCTAATAGTTTCATGTGAGAGACATGCTGTATGATGTCGTCAGTGAGAAACAGCCAAACAGGTCCTAAGCAGCTCTGGTGTTCTATTTTGCAGCTCATACGTTAAGCCTGAGCTTTTACTTTAACAACTGTTGTCTCTGATTTGTTACTTGCCACCAAAATAAAACAGTAGAATGTAACTGGGTAGTGGTCCCTTGGCATGTAAACTTTGATTCAGCTGATTACAAAGCTTTCTGACTGCATTCTGGATCCATTGCTTATATAGCTAGCAGGAGCCTTTTCTTGTGCC
CDS Sequence
- >Zm00001eb153890_T001
ATGGCTGCAATGGTTGGAGCGCGTAGGGCGCTCTTGGCCGCTCGGTTCTCTCCTCGCGGCACCATCGCGGCGTCGGCCGCGCCAGCTCCCCTCTACCGGCCCATGGATTCGCCACTCAGGCTTCCAGCTGAAAGAGTTTGTCTACAGTCTTGGGTTCCACATCGAGGGGCTGGTACCTTTGCATCTGAAAGGACTGATGAAGATTATCAGCGTGAGTGGGGACAAAACAAAGCAGGTAGCTACACTGACTCCCGTTGGAACGGCTCTAATCTCCAACTTCAGAGAGATGTCACTTCAGCTGGTTCCACAACAGGTACTCACAAAAATAAGGGTGTGGATGGTGTTGGTGGCAGTTCTGAGCAACATTACAGAAGTGGTGGATCATATGGCTTTCAAAACAATCATCAGCCATATACTGGTACAAGAGCGAATAATGAGAGATACAATGCATCACAACCTTATAGAGGTAGTGGTCCATACAGCCAGCAAGGCCTTGATGGACATTTTTCAAATGATCGTCAACAGTACAATGGCACAGAAGCTAATAGTACATATAGCTCTGGATACTACACCCAAAGTAAGCAGAAGATTTATGAAGGAGAGGGAGCTAATAATGGGCAGTATGGATATGGTCCTTCAGGACAACCATGTCCGAACCCAGTTGGAAATAGCCAGCGAGTTCAGAAACAGCAATATGTTGATCATAGATCTGGGGGAAGTTATCCAGATAGATCTGGGCATCATCCCTCTCAATATGTAAATCCAACTCATTCCCGTAAGGAGCATGTTGCAGGGTTTCAGCAAGGCAACAATAGTAATTTTGGATATAATGCTTCGCAGGCATATCAAAGCCCTTATTTCACTAGGCAGGCTGATACACATAGTACTTCTCAAGGATATTCCATGTACCTAAATACAGATGTGCAACGCCTCTCTCATGGAGTTCATCAAGAAAAACATTCACATGCACAATCTGCTGGATCATTTGGGAACCATGTAAATAGTGCACCTCATGAATATGGCAAATATCATCAGTCACTACAAGGCAACCCTTCAAATGTTGGATCGCCTTACGAAGTACCTAGTGAAGCTGGCAGCAAACACAAATGTACTGTTGAAGAACTGGAGAAGTTTTGTGATGATGGCAATGTAAAAGAAGCTCTGGAAGTTTTGGCTATGCTAAAGGAAAACAGAATTGTGCTACATGCTCCTCAGTACTTCAGATTGATGCAAGCATGTGGTGATGCAACTGCCCTTTCAGAAGCAAGATTAATACATAGTCAAATATCTGAATCATCACTTACTGTTGACACAGATTTTCAAAACAAAATTATGGAGATGTATGCTAGGTGTGGTTCTATGGAAGATGCAAAGAAGATTTTCAGTTCTATGGATCATCATAATTTGACTTCTTGGAACACTATGATCTCAGGTTTTGTGCACAATGTTCTTGGTGAAGAAGCAATAGATTTTTTTGAACGGTTTAAGCAGACAGGGGACAAGCCAGATCATGGCATGTTCAGACATGTTTTCTTGGCATGTGGAATTTTGGGATCTGTTAATGAAGGAATGTTGCATTTTGAATCCATGCAGAAAGATTTTGGCATACATCCCACTACAGAGCATTATGCAAGCATTGTTACTATGCTTGGACAGTCTGGCTACATTGTCGAGGCTTATGAATTCGTGGAACGGATGCCTGTGGAACCAAGCATTGAGGTATGGGAAAATTTGATGAACATGTGTCGACTTAATGGCTTTTTAGAGCTTGGAGATCGTTGTGCTCAGATCATAGAGTGCTTGGATTCTTCTAGGCTGAATGAACAGTCTAAAATGGGTCTGTTCCCTGTCGATGTGTCAGATCTTGCAAAGGAAAAGGAAAGGAAAAAGGCAAGTGTCGCCGAAGCTCGGAGCAAGGTCCATGAATACAGAGCTGGCGACCGATCTCACCCTGACACTCCTAAGATCTATGAAGAGCTGAGGTATTTGTTGGCTCACATGAAGGAAGCTGGGTATATTGCTGACACTCGATTTGTTCTTCACGATGTTGATCAAGAAACCAAAGAGGATGCTTTACTGGCTCACAGTGAGAGGCTGGCTATCAGTTACGGTCTTATAACAAGTGCTCCCCGCTCACCTATTCGGGTTATAAAGAATCTTCGATCCTGTGGGGATTGTCACACGGCTTTCAAGATAATCTCAAAACTTGTTGGACGTCAGATCATTGCAAGGGATGCAAAGAGGTTCCACCACTTCGAAAATGGTGTGTGTTCTTGCAAAGACTACTGGTAA
Protein Sequence
- >Zm00001eb153890_P001
MAAMVGARRALLAARFSPRGTIAASAAPAPLYRPMDSPLRLPAERVCLQSWVPHRGAGTFASERTDEDYQREWGQNKAGSYTDSRWNGSNLQLQRDVTSAGSTTGTHKNKGVDGVGGSSEQHYRSGGSYGFQNNHQPYTGTRANNERYNASQPYRGSGPYSQQGLDGHFSNDRQQYNGTEANSTYSSGYYTQSKQKIYEGEGANNGQYGYGPSGQPCPNPVGNSQRVQKQQYVDHRSGGSYPDRSGHHPSQYVNPTHSRKEHVAGFQQGNNSNFGYNASQAYQSPYFTRQADTHSTSQGYSMYLNTDVQRLSHGVHQEKHSHAQSAGSFGNHVNSAPHEYGKYHQSLQGNPSNVGSPYEVPSEAGSKHKCTVEELEKFCDDGNVKEALEVLAMLKENRIVLHAPQYFRLMQACGDATALSEARLIHSQISESSLTVDTDFQNKIMEMYARCGSMEDAKKIFSSMDHHNLTSWNTMISGFVHNVLGEEAIDFFERFKQTGDKPDHGMFRHVFLACGILGSVNEGMLHFESMQKDFGIHPTTEHYASIVTMLGQSGYIVEAYEFVERMPVEPSIEVWENLMNMCRLNGFLELGDRCAQIIECLDSSRLNEQSKMGLFPVDVSDLAKEKERKKASVAEARSKVHEYRAGDRSHPDTPKIYEELRYLLAHMKEAGYIADTRFVLHDVDQETKEDALLAHSERLAISYGLITSAPRSPIRVIKNLRSCGDCHTAFKIISKLVGRQIIARDAKRFHHFENGVCSCKDYW
Source: Genetic information comes from the article