Gene Details:

• Gene ID: Zm00001eb151670
• Gene Symbol: ZmCKX4a|ZmCKO4
• Gene Name: cytokinin oxidase 4
• Genome: Zm-B73-REFERENCE-NAM-5.0
• Species: Zea mays

Functional Descriptions:

• ZmARF29 (Zm00001d026540, encoding auxin response factor 29) and ZmCKX4a|ZmCKO4 (Zm00001d043293, encoding cytokinin oxidase protein) were significantly related to KRN, based on expression analysis and candidate gene association mapping.
• The best inhibitors exhibited half-maximal inhibitory concentration (IC50) values in low nanomolar ranges with ZmCKX1 and especially with ZmCKX4a|ZmCKO4, which is generally more resistant to inhibition.
• The introduction of a fluorine or chlorine atom to the 5th position of the CKX inhibitors studied here was a key factor that improvesdthe selectivity to, and inhibitory strength against ZmCKX1 and ZmCKX4a|ZmCKO4.

Function-related keywords:

• auxin ,  cytokinin ,  auxin-response ,  resistant ,  cytokinin-response ,  protein

Literature:

• Cytokinin oxidase/dehydrogenase inhibitors: outlook for selectivity and high efficiency.   DOI:  10.1093/jxb/erac201 ;  PMID:  35522987

Related News:

Gene Resources:

• NCBI ID: LOC100272805
• UniProt accessions: A0A1D6NA77

Orthologs:

Sequences:

Source: Genetic information comes from the article