Gene Details:

• Gene ID: Zm00001eb144310
• Gene Symbol: ZmSMC2
• Gene Name: structural maintenance of chromosomes2
• Genome: Zm-B73-REFERENCE-NAM-5.0
• Species: Zea mays

Functional Descriptions:

• Identified ZmSMC2 and ZmSMC4 in maize (Zea mays) and confirmed that ZmSMC2 associates with ZmSMC4 via their hinge domains.
• Knockdown and knockout of ZmSMC2 and ZmSMC4 result in abnormal location of H3Ser10 phosphorylation.
• ZmSMC2 and ZmSMC4 are essential for proper chromosome segregation and for H3 phosphorylation at Serine 10 (H3S10ph) at pericentromeres during mitotic division.
• Taken together, these findings confirm and extend the coordinated role of ZmSMC2 and ZmSMC4 in maintenance of normal chromosome architecture and accurate segregation during mitosis.

Function-related keywords:

• architecture ,  mitosis

Literature:

• Design of high-oleic tobacco (Nicotiana tabacum L.) seed oil by CRISPR-Cas9-mediated knockout of NtFAD2-2.   DOI:  10.1186/s12870-020-02441-0 ;  PMID:  32450806

Related News:

Gene Resources:

• NCBI ID: LOC103650874
• UniProt accessions: A0A804N953

Orthologs:

Sequences:

Source: Genetic information comes from the article