Gene Details:

• Gene ID: Zm00001eb112950
• Gene Symbol: ZmHSD1
• Gene Name: hydroxysteroid dehydrogenase 1
• Genome: Zm-B73-REFERENCE-NAM-5.0
• Species: Zea mays

Functional Descriptions:

• ZmC2H2-149 negatively regulates drought tolerance by repressing ZmHSD1 in maize.
• By subjecting 150 Ac/Ds mutant lines to drought stress, we successfully identified a Ds-insertion mutant, zmc2h2-149, which shows increased tolerance to drought stress.
• Overexpression of ZmC2H2-149 in maize led to a decrease in both drought tolerance and crop yield. DAP-Seq, RNA-Seq, Y1H and LUC assays additionally showed that ZmC2H2-149 directly suppresses the expression of a positive drought tolerance regulator, ZmHSD1 (hydroxysteroid dehydrogenase 1).
• ZmC2H2-149 represses the expression of Zm00001d007345 (hydroxysteroid dehydrogenase 1, ZmHSD1) to negatively regulate drought tolerance and leads to yield loss in maize. These findings indicated that both ZmC2H2-149 and ZmHSD1, which are regulated by ZmC2H2-149, play important roles in drought tolerance.

Function-related keywords:

• drought ,  stress ,  drought-stress ,  tolerance ,  yield ,  drought-tolerance ,  stress-tolerance ,  dehydrogenase

Literature:

• ZmC2H2-149 negatively regulates drought tolerance by repressing ZmHSD1 in maize.   DOI:  10.1111/pce.14798 ;  PMID:  38164019

Related News:

Gene Resources:

• NCBI ID: LOC103648012
• UniProt accessions: A0A804MUR8

Orthologs:

Sequences:

Source: Genetic information comes from the article