Information report for Zmlox4
Gene Details
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Functional Descriptions
- The transcripts of Zmlox4 accumulated predominantly in roots and shoot apical meristem, whereas ZmLOX5 was expressed in most tested aboveground organs.
- While Zmlox4 was only induced by jasmonic acid (JA), the transcripts of ZmLOX5 were increased in response to JA and salicylic acid treatments. ZmLOX5 was transiently induced both locally and systemically by wounding, which was accompanied by increased levels of 9-oxylipins, and fall armyworm herbivory, suggesting a putative role for this gene in defense against insects.
- Surprisingly, despite of moderate JA- and wound-inducibility of Zmlox4, the gene was not responsive to insect herbivory.
- These results clearly indicated that no NIP exists in the maize genome that is closely related to Zmlox4 and ZmLOX5.
Functional Keywords
- shoot , ja , defense-response , defense , insect , salicylic-acid , meristem , jasmonic , jasmonic-acid , shoot-apical-meristem , wounding , wounding-response , shoot-meristem
Literature and News
Gene Resources
- NCBI ID: LOC100037803
- UniProt accessions: A0A1D6L0K7
- EMBL: CM007647
- AlphaFoldDB: A0A1D6L0K7
- InterPro: IPR000907 , IPR001024 , IPR001246 , IPR036392 , IPR042057
- PANTHER: PTHR11771
- SUPFAM: SSF49723
- PROSITE: PS50095
- Gene3D: 2.60.60.20
- CDD: cd01751
Sequences
cDNA Sequence
- >Zm00001eb054050_T002
GTAGCCCCGGACATGGAATGGAACAGTTGTTTGGGGGCATTCAATGCGATTGAGATGGCGTCCGTGAAAACTTTACTGTAATTTTCACTGCAAACGATTGATTGACTGATTGATTGAACGAGTCTTCAGGCAACGGGAGCCGCGGCAAGGTCGGGAAGGCGGCGCACCTGGAGGAGGCGGTGGTGTCGCTCAAGTCGACGACGGACGGGGAGACCGTGTACCGGGTGAGCTTCGAGTGGGACGGGTCGCAGGGCGTCCCGGGCGCCGTCCTGGTCAGGAACCTGCAGCACGCCGAGTTCTTCCTCAAGTCGCTCACCCTCGAGGGCGTCCCCGGCAGGGGCACCGTCGTCTTCGTCGCCAACTCGTGGATCTACCCGCACAATCTCTACTCCCAGGAACGCGTCTTCTTCGCCAACGACACTTATCTGCCAAGCAAAATGCCTGCGGCATTGGTGCCTTACCGGCAGGACGAGCTCAAGATTCTCCGCGGCGACGATAATCCTGGACCATACAAGGAGCACGACCGCGTCTACCGTTACGACTACTACAACGACCTCGGTGAGCCAGACAAGGGTGAAGACCATGCCCGGCCTGTCCTCGGGGGCAGCCAAGAACACCCGTATCCCCGTCGCTGCAGGACCGGCCGGCGTCCAACAGAGACAGACCCCAACTCGGAGAGCAGGCTGTTTCTGCTGAACCTGAACATCTACGTCCCGCGCGACGAGCGGTTTGGGCATCTCAAGATGTCGGACTTCCTCGGGTACTCACTGAAGGCGATCATCGAGGCTGTCCTTCCGACGCTGGGGACGTTCGTCGACGATACGCCCAAGGAGTTCGATTCGTTCGAAGACATCCTTGGGCTCTACGAGCCGGGTCCAGAGGCGCCCAACAACCCACTGGTAGCAGAGGTCAGGAAGAGAATCCCCAGCGAGTTCCTCAGAAGCATTCTGCCCAATGGTAGCCATGACCACCCCCTGAAGATGCCCCTTCCAAATATCATCAGATCAGATGTGTTGAAAAAGGCTCCAGAGTTTAAGTTTGGCTGGAGGACCGACGAAGAGTTTGCGAGGGAGACGCTTGCAGGCGTGAACCCAGTGCTCATCAAACGTCTGACGGAGTTCCCAGCTAAAAGTACCCTGGACCCAAGTCAATACGGAGACCATACGAGCAAGATCACCGAAGCTCACATCCAGCATAACATGGAAGGCCTGTCAGTGCAGAATGCACTGAAGAAGAACAGGCTCTTCATCCTAGACCACCATGACCATTTCATGCCGTACCTCAACAAGATCAACGAGTTGGAGGGGAACTTCATCTACGCCAGCAGGACCCTACTGTTCCTGAAGGACGATGGCACGCTGAAGCCCCTGGCCGTCGAGCTGAGCCTGCCCCACCCTGATGGCCAGCAGCACGGCGCGGTCAGCAAGGTGTACACCCCAGCTCACTCCGGCGCTGAGGGCCACGTCTGGCAACTTGCCAAGGCTTATGCCTGCGTGAACGACTCCGCCTGGCATCAGCTGATCAGCCACTGGCTGAACACGCACGCGGTGATCGAGCCGTTCGTCATCGCAACGAACCGGCAGCTGAGCGTGGTGCATCCAGTGCACAAGCTGCTGAGCCCACACTACCGTGACACGCTGAACATCAACGCCCTGGCACGCCAGACGCTCATCAACGCCGACGGCATCTTCGAGCGCACCGTGTTCCCTGCAAAGTACGCGCTGGGGATGTCCTCCGACGTGTACAAGAGCTGGAATTTCAACGAGCAGGCTCTCCCAGCAGACCTCGTCAAGAGAGGTGTGGCTGTGCCGGACCAGTCGAGCCCCTACGGTGTCCGGTTGCTGATCAAGGACTACCCTTACGCCGTGGACGGGCTGGTCATCTGGTGGGCGATCGAGCGGTGGGTCAAGGAGTACCTGGACGTCTACTACCCCAACGACGGCGAGCTCCAGCGCGACGTGGAGCTGCAGGCGTGGTGGAAGGAGGTGCGCGAGGAGGCGCACGGCGACCTCAAGGACCGAGACTGGTGGCCCAGGATGGACGCCGTCCAGCGGCTGGCCAGGGCGTGCACGACCGTCATCTGGGTAGCGTCCGCGCTGCACGCGGCCGTCAACTTCGGGCAGTACCCGTACGCCGGGTACCTGCCGAACCGGCCGACCGTGAGCCGGCGGCCGATGCCGGAGCCGGGCAGCGACGACTACAAGAAGCTGGAGGCGGGGCAGAAGGAGGCGGACGCGGTGTTCATCCGCACCATCACCAGCCAGTTCCAGACCATCCTGGGCATCTCGCTCATCGAGATCCTCTCCAAGCACTCCTCCGACGAGGTGTACCTCGGCCAGCGCGACGAGCCTGAGCGCTGGACGTCGGACGCCAGGGCGCTGGACGCGTTCAGAAGGTTCGGAAGCCGGCTGGTGGAGATCGAGAAGCGGATCAGGACGATGAACGACAGCCCGACGTTGAAGAACCGGAAGGGGCCGGTGGAGATGCCGTACATGCTGCTGTACCCCAACACGTCGGATGTCACCGGCGAGAAGGGCGAGGGGCTCACTGCCATGGGCATTCCCAACAGCATCTCCATATGAGCCTCCTCACTGCCTGAGCGGATGGTTTGTAGATGTTCTGTTACGCTGTGTGTAATGTGTCGTTTATTCGTTGGTTTTGTCAGTCTCAGGGTAGGGAATGGAGATGTTGATTGGATCCATGATCTGTAGGGTTGAGAGAGGAGTCACGTCTGGAGAATGTTGTCAATGTGTGTTTCTTTCTTGTTAAGAATAAAAGTTCGTCAGCTCATTTATCTCT - >Zm00001eb054050_T001
GTAGCCCCGGACATGGAATGGAACAGTTGTTTGGGGGCATTCAATGCGATTGAGATGGCGTCCGTGAAAACTTTACTGTAATTTTCACTGCAAACGATTGATTGACTGATTGATTGAACGAGTCTTCAGGCAACGGGAGCCGCGGCAAGGTCGGGAAGGCGGCGCACCTGGAGGAGGCGGTGGTGTCGCTCAAGTCGACGACGGACGGGGAGACCGTGTACCGGGTGAGCTTCGAGTGGGACGGGTCGCAGGGCGTCCCGGGCGCCGTCCTGGTCAGGAACCTGCAGCACGCCGAGTTCTTCCTCAAGTCGCTCACCCTCGAGGGCGTCCCCGGCAGGGGCACCGTCGTCTTCGTCGCCAACTCGTGGATCTACCCGCACAATCTCTACTCCCAGGAACGCGTCTTCTTCGCCAACGACACTTATCTGCCAAGCAAAATGCCTGCGGCATTGGTGCCTTACCGGCAGGACGAGCTCAAGATTCTCCGCGGCGACGATAATCCTGGACCATACAAGGAGCACGACCGCGTCTACCGTTACGACTACTACAACGACCTCGGTGAGCCAGACAAGGGTGAAGACCATGCCCGGCCTGTCCTCGGGGGCAGCCAAGAACACCCGTATCCCCGTCGCTGCAGGACCGGCCGGCGTCCAACAGAGACAGACCCCAACTCGGAGAGCAGGCTGTTTCTGCTGAACCTGAACATCTACGTCCCGCGCGACGAGCGGTTTGGGCATCTCAAGATGTCGGACTTCCTCGGGTACTCACTGAAGGCGATCATCGAGGCTGTCCTTCCGACGCTGGGGACGTTCGTCGACGATACGCCCAAGGAGTTCGATTCGTTCGAAGACATCCTTGGGCTCTACGAGCCGGGTCCAGAGGCGCCCAACAACCCACTGGTAGCAGAGGTCAGGAAGAGAATCCCCAGCGAGTTCCTCAGAAGCATTCTGCCCAATGGTAGCCATGACCACCCCCTGAAGATGCCCCTTCCAAATATCATCAGATCAGATGTGTTGAAAAAGGCTCCAGAGTTTAAGTTTGGCTGGAGGACCGACGAAGAGTTTGCGAGGGAGACGCTTGCAGGCGTGAACCCAGTGCTCATCAAACGTCTGACGGAGTTCCCAGCTAAAAGTACCCTGGACCCAAGTCAATACGGAGACCATACGAGCAAGATCACCGAAGCTCACATCCAGCATAACATGGAAGGCCTGTCAGTGCAGAATGCACTGAAGAAGAACAGGCTCTTCATCCTAGACCACCATGACCATTTCATGCCGTACCTCAACAAGATCAACGAGTTGGAGGGGAACTTCATCTACGCCAGCAGGACCCTACTGTTCCTGAAGGACGATGGCACGCTGAAGCCCCTGGCCGTCGAGCTGAGCCTGCCCCACCCTGATGGCCAGCAGCACGGCGCGGTCAGCAAGGTGTACACCCCAGCTCACTCCGGCGCTGAGGGCCACGTCTGGCAACTTGCCAAGGCTTATGCCTGCGTGAACGACTCCGCCTGGCATCAGCTGATCAGCCACTGGCTGAACACGCACGCGGTGATCGAGCCGTTCGTCATCGCAACGAACCGGCAGCTGAGCGTGGTGCATCCAGTGCACAAGCTGCTGAGCCCACACTACCGTGACACGCTGAACATCAACGCCCTGGCACGCCAGACGCTCATCAACGCCGACGGCATCTTCGAGCGCACCGTGTTCCCTGCAAAGTACGCGCTGGGGATGTCCTCCGACGTGTACAAGAGCTGGAATTTCAACGAGCAGGCTCTCCCAGCAGACCTCGTCAAGAGAGGTGTGGCTGTGCCGGACCAGTCGAGCCCCTACGGTGTCCGGTTGCTGATCAAGGACTACCCTTACGCCGTGGACGGGCTGGTCATCTGGTGGGCGATCGAGCGGTGGGTCAAGGAGTACCTGGACGTCTACTACCCCAACGACGGCGAGCTCCAGCGCGACGTGGAGCTGCAGGCGTGGTGGAAGGAGGTGCGCGAGGAGGCGCACGGCGACCTCAAGGACCGAGACTGGTGGCCCAGGATGGACGCCGTCCAGCGGCTGGCCAGGGCGTGCACGACCGTCATCTGGGTAGCGTCCGCGCTGCACGCGGCCGTCAACTTCGGGCAGTACCCGTACGCCGGGTACCTGCCGAACCGGCCGACCGTGAGCCGGCGGCCGATGCCGGAGCCGGGCAGCGACGACTACAAGAAGCTGGAGGCGGGGCAGAAGGAGGCGGACGCGGTGTTCATCCGCACCATCACCAGCCAGTTCCAGACCATCCTGGGCATCTCGCTCATCGAGATCCTCTCCAAGCACTCCTCCGACGAGGTGTACCTCGGCCAGCGCGACGAGCCTGAGCGCTGGACGTCGGACGCCAGGGCGCTGGACGCGTTCAGAAGGTTCGGAAGCCGGCTGGTGGAGATCGAGAAGCGGATCAGGACGATGAACGACAGCCCGACGTTGAAGAACCGGAAGGGGCCGGTGGAGATGCCGTACATGCTGCTGTACCCCAACACGTCGGATGTCACCGGCGAGAAGGGCGAGGGGCTCACTGCCATGGGCATTCCCAACAGCATCTCCATATGAGCCTCCTCACTGCCTGAGCGGATGGTTTGTAGATGTTCTGTTACGCTGTGTGTAATGTGTCGTTTATTCGTTGGTTTTGTCAGTCTCAGGGTAGGGAATGGAGATGTTGATTGGATCCATGATCTGTAGGGTTGAGAGAGGAGTCACGTCTGGAGAATGTTGTCAATGTGTGTTTCTTTCTTGTTAAGAATAAAAGTTCGTCAGCTCATTTATCTCT
CDS Sequence
- >Zm00001eb054050_T002
ATGCCTGCGGCATTGGTGCCTTACCGGCAGGACGAGCTCAAGATTCTCCGCGGCGACGATAATCCTGGACCATACAAGGAGCACGACCGCGTCTACCGTTACGACTACTACAACGACCTCGGTGAGCCAGACAAGGGTGAAGACCATGCCCGGCCTGTCCTCGGGGGCAGCCAAGAACACCCGTATCCCCGTCGCTGCAGGACCGGCCGGCGTCCAACAGAGACAGACCCCAACTCGGAGAGCAGGCTGTTTCTGCTGAACCTGAACATCTACGTCCCGCGCGACGAGCGGTTTGGGCATCTCAAGATGTCGGACTTCCTCGGGTACTCACTGAAGGCGATCATCGAGGCTGTCCTTCCGACGCTGGGGACGTTCGTCGACGATACGCCCAAGGAGTTCGATTCGTTCGAAGACATCCTTGGGCTCTACGAGCCGGGTCCAGAGGCGCCCAACAACCCACTGGTAGCAGAGGTCAGGAAGAGAATCCCCAGCGAGTTCCTCAGAAGCATTCTGCCCAATGGTAGCCATGACCACCCCCTGAAGATGCCCCTTCCAAATATCATCAGATCAGATGTGTTGAAAAAGGCTCCAGAGTTTAAGTTTGGCTGGAGGACCGACGAAGAGTTTGCGAGGGAGACGCTTGCAGGCGTGAACCCAGTGCTCATCAAACGTCTGACGGAGTTCCCAGCTAAAAGTACCCTGGACCCAAGTCAATACGGAGACCATACGAGCAAGATCACCGAAGCTCACATCCAGCATAACATGGAAGGCCTGTCAGTGCAGAATGCACTGAAGAAGAACAGGCTCTTCATCCTAGACCACCATGACCATTTCATGCCGTACCTCAACAAGATCAACGAGTTGGAGGGGAACTTCATCTACGCCAGCAGGACCCTACTGTTCCTGAAGGACGATGGCACGCTGAAGCCCCTGGCCGTCGAGCTGAGCCTGCCCCACCCTGATGGCCAGCAGCACGGCGCGGTCAGCAAGGTGTACACCCCAGCTCACTCCGGCGCTGAGGGCCACGTCTGGCAACTTGCCAAGGCTTATGCCTGCGTGAACGACTCCGCCTGGCATCAGCTGATCAGCCACTGGCTGAACACGCACGCGGTGATCGAGCCGTTCGTCATCGCAACGAACCGGCAGCTGAGCGTGGTGCATCCAGTGCACAAGCTGCTGAGCCCACACTACCGTGACACGCTGAACATCAACGCCCTGGCACGCCAGACGCTCATCAACGCCGACGGCATCTTCGAGCGCACCGTGTTCCCTGCAAAGTACGCGCTGGGGATGTCCTCCGACGTGTACAAGAGCTGGAATTTCAACGAGCAGGCTCTCCCAGCAGACCTCGTCAAGAGAGGTGTGGCTGTGCCGGACCAGTCGAGCCCCTACGGTGTCCGGTTGCTGATCAAGGACTACCCTTACGCCGTGGACGGGCTGGTCATCTGGTGGGCGATCGAGCGGTGGGTCAAGGAGTACCTGGACGTCTACTACCCCAACGACGGCGAGCTCCAGCGCGACGTGGAGCTGCAGGCGTGGTGGAAGGAGGTGCGCGAGGAGGCGCACGGCGACCTCAAGGACCGAGACTGGTGGCCCAGGATGGACGCCGTCCAGCGGCTGGCCAGGGCGTGCACGACCGTCATCTGGGTAGCGTCCGCGCTGCACGCGGCCGTCAACTTCGGGCAGTACCCGTACGCCGGGTACCTGCCGAACCGGCCGACCGTGAGCCGGCGGCCGATGCCGGAGCCGGGCAGCGACGACTACAAGAAGCTGGAGGCGGGGCAGAAGGAGGCGGACGCGGTGTTCATCCGCACCATCACCAGCCAGTTCCAGACCATCCTGGGCATCTCGCTCATCGAGATCCTCTCCAAGCACTCCTCCGACGAGGTGTACCTCGGCCAGCGCGACGAGCCTGAGCGCTGGACGTCGGACGCCAGGGCGCTGGACGCGTTCAGAAGGTTCGGAAGCCGGCTGGTGGAGATCGAGAAGCGGATCAGGACGATGAACGACAGCCCGACGTTGAAGAACCGGAAGGGGCCGGTGGAGATGCCGTACATGCTGCTGTACCCCAACACGTCGGATGTCACCGGCGAGAAGGGCGAGGGGCTCACTGCCATGGGCATTCCCAACAGCATCTCCATATGA - >Zm00001eb054050_T001
ATGCCTGCGGCATTGGTGCCTTACCGGCAGGACGAGCTCAAGATTCTCCGCGGCGACGATAATCCTGGACCATACAAGGAGCACGACCGCGTCTACCGTTACGACTACTACAACGACCTCGGTGAGCCAGACAAGGGTGAAGACCATGCCCGGCCTGTCCTCGGGGGCAGCCAAGAACACCCGTATCCCCGTCGCTGCAGGACCGGCCGGCGTCCAACAGAGACAGACCCCAACTCGGAGAGCAGGCTGTTTCTGCTGAACCTGAACATCTACGTCCCGCGCGACGAGCGGTTTGGGCATCTCAAGATGTCGGACTTCCTCGGGTACTCACTGAAGGCGATCATCGAGGCTGTCCTTCCGACGCTGGGGACGTTCGTCGACGATACGCCCAAGGAGTTCGATTCGTTCGAAGACATCCTTGGGCTCTACGAGCCGGGTCCAGAGGCGCCCAACAACCCACTGGTAGCAGAGGTCAGGAAGAGAATCCCCAGCGAGTTCCTCAGAAGCATTCTGCCCAATGGTAGCCATGACCACCCCCTGAAGATGCCCCTTCCAAATATCATCAGATCAGATGTGTTGAAAAAGGCTCCAGAGTTTAAGTTTGGCTGGAGGACCGACGAAGAGTTTGCGAGGGAGACGCTTGCAGGCGTGAACCCAGTGCTCATCAAACGTCTGACGGAGTTCCCAGCTAAAAGTACCCTGGACCCAAGTCAATACGGAGACCATACGAGCAAGATCACCGAAGCTCACATCCAGCATAACATGGAAGGCCTGTCAGTGCAGAATGCACTGAAGAAGAACAGGCTCTTCATCCTAGACCACCATGACCATTTCATGCCGTACCTCAACAAGATCAACGAGTTGGAGGGGAACTTCATCTACGCCAGCAGGACCCTACTGTTCCTGAAGGACGATGGCACGCTGAAGCCCCTGGCCGTCGAGCTGAGCCTGCCCCACCCTGATGGCCAGCAGCACGGCGCGGTCAGCAAGGTGTACACCCCAGCTCACTCCGGCGCTGAGGGCCACGTCTGGCAACTTGCCAAGGCTTATGCCTGCGTGAACGACTCCGCCTGGCATCAGCTGATCAGCCACTGGCTGAACACGCACGCGGTGATCGAGCCGTTCGTCATCGCAACGAACCGGCAGCTGAGCGTGGTGCATCCAGTGCACAAGCTGCTGAGCCCACACTACCGTGACACGCTGAACATCAACGCCCTGGCACGCCAGACGCTCATCAACGCCGACGGCATCTTCGAGCGCACCGTGTTCCCTGCAAAGTACGCGCTGGGGATGTCCTCCGACGTGTACAAGAGCTGGAATTTCAACGAGCAGGCTCTCCCAGCAGACCTCGTCAAGAGAGGTGTGGCTGTGCCGGACCAGTCGAGCCCCTACGGTGTCCGGTTGCTGATCAAGGACTACCCTTACGCCGTGGACGGGCTGGTCATCTGGTGGGCGATCGAGCGGTGGGTCAAGGAGTACCTGGACGTCTACTACCCCAACGACGGCGAGCTCCAGCGCGACGTGGAGCTGCAGGCGTGGTGGAAGGAGGTGCGCGAGGAGGCGCACGGCGACCTCAAGGACCGAGACTGGTGGCCCAGGATGGACGCCGTCCAGCGGCTGGCCAGGGCGTGCACGACCGTCATCTGGGTAGCGTCCGCGCTGCACGCGGCCGTCAACTTCGGGCAGTACCCGTACGCCGGGTACCTGCCGAACCGGCCGACCGTGAGCCGGCGGCCGATGCCGGAGCCGGGCAGCGACGACTACAAGAAGCTGGAGGCGGGGCAGAAGGAGGCGGACGCGGTGTTCATCCGCACCATCACCAGCCAGTTCCAGACCATCCTGGGCATCTCGCTCATCGAGATCCTCTCCAAGCACTCCTCCGACGAGGTGTACCTCGGCCAGCGCGACGAGCCTGAGCGCTGGACGTCGGACGCCAGGGCGCTGGACGCGTTCAGAAGGTTCGGAAGCCGGCTGGTGGAGATCGAGAAGCGGATCAGGACGATGAACGACAGCCCGACGTTGAAGAACCGGAAGGGGCCGGTGGAGATGCCGTACATGCTGCTGTACCCCAACACGTCGGATGTCACCGGCGAGAAGGGCGAGGGGCTCACTGCCATGGGCATTCCCAACAGCATCTCCATATGA
Protein Sequence
- >Zm00001eb054050_P002
MPAALVPYRQDELKILRGDDNPGPYKEHDRVYRYDYYNDLGEPDKGEDHARPVLGGSQEHPYPRRCRTGRRPTETDPNSESRLFLLNLNIYVPRDERFGHLKMSDFLGYSLKAIIEAVLPTLGTFVDDTPKEFDSFEDILGLYEPGPEAPNNPLVAEVRKRIPSEFLRSILPNGSHDHPLKMPLPNIIRSDVLKKAPEFKFGWRTDEEFARETLAGVNPVLIKRLTEFPAKSTLDPSQYGDHTSKITEAHIQHNMEGLSVQNALKKNRLFILDHHDHFMPYLNKINELEGNFIYASRTLLFLKDDGTLKPLAVELSLPHPDGQQHGAVSKVYTPAHSGAEGHVWQLAKAYACVNDSAWHQLISHWLNTHAVIEPFVIATNRQLSVVHPVHKLLSPHYRDTLNINALARQTLINADGIFERTVFPAKYALGMSSDVYKSWNFNEQALPADLVKRGVAVPDQSSPYGVRLLIKDYPYAVDGLVIWWAIERWVKEYLDVYYPNDGELQRDVELQAWWKEVREEAHGDLKDRDWWPRMDAVQRLARACTTVIWVASALHAAVNFGQYPYAGYLPNRPTVSRRPMPEPGSDDYKKLEAGQKEADAVFIRTITSQFQTILGISLIEILSKHSSDEVYLGQRDEPERWTSDARALDAFRRFGSRLVEIEKRIRTMNDSPTLKNRKGPVEMPYMLLYPNTSDVTGEKGEGLTAMGIPNSISI - >Zm00001eb054050_P001
MPAALVPYRQDELKILRGDDNPGPYKEHDRVYRYDYYNDLGEPDKGEDHARPVLGGSQEHPYPRRCRTGRRPTETDPNSESRLFLLNLNIYVPRDERFGHLKMSDFLGYSLKAIIEAVLPTLGTFVDDTPKEFDSFEDILGLYEPGPEAPNNPLVAEVRKRIPSEFLRSILPNGSHDHPLKMPLPNIIRSDVLKKAPEFKFGWRTDEEFARETLAGVNPVLIKRLTEFPAKSTLDPSQYGDHTSKITEAHIQHNMEGLSVQNALKKNRLFILDHHDHFMPYLNKINELEGNFIYASRTLLFLKDDGTLKPLAVELSLPHPDGQQHGAVSKVYTPAHSGAEGHVWQLAKAYACVNDSAWHQLISHWLNTHAVIEPFVIATNRQLSVVHPVHKLLSPHYRDTLNINALARQTLINADGIFERTVFPAKYALGMSSDVYKSWNFNEQALPADLVKRGVAVPDQSSPYGVRLLIKDYPYAVDGLVIWWAIERWVKEYLDVYYPNDGELQRDVELQAWWKEVREEAHGDLKDRDWWPRMDAVQRLARACTTVIWVASALHAAVNFGQYPYAGYLPNRPTVSRRPMPEPGSDDYKKLEAGQKEADAVFIRTITSQFQTILGISLIEILSKHSSDEVYLGQRDEPERWTSDARALDAFRRFGSRLVEIEKRIRTMNDSPTLKNRKGPVEMPYMLLYPNTSDVTGEKGEGLTAMGIPNSISI