Gene Details:
- Gene ID: Zm00001d018330
- Gene Symbol: ZmmtRF2a
- Gene Name: crumpled kernel5
- Genome: Zm-B73-REFERENCE-GRAMENE-4.0
- Species: Zea mays
Functional Descriptions:
- ZmmtRF2a is missing the 5th–7th exons in the crk5 resulting in deletion of domains containing motifs GGQ and SPF that are essential for release activity of RF, mitochondrial ribosome binding, and stop codon recognition.
- Our results showed that the loss of ZmmtRF2a function alters the transcript and protein levels for several important components of both the mitochondrial transport chain complex and mitochondrial ribosome. The study sheds light on the function of mtRF2 in the mitochondrial translation system.
- ZmmtRF2a is constitutively expressed, and its protein is localized to mitochondria.
- Together, our data support a crucial role for ZmmtRF2a in regulation of mitochondrial structure and function in maize.
Function-related keywords:
Literature:
- A peptide chain release factor 2a gene regulates maize kernel development by modulating mitochondrial function. DOI: 10.1016/j.cj.2023.10.006
Related News:
Gene Resources:
- NCBI ID: LOC100281737
- UniProt accessions: B8A2E4
Orthologs:
Sequences:
cDNA Sequence
- >Zm00001eb397500_T001
ACTTTCCCATCAACTCGCAATTCCGCATTCGTTCCAACTCCTGAGCACTTTCTCCTCGTCCCCGACAAGCCAATCGAAGCCGAGATACGGCCATGGACTCCACCGGCACCGGAGCAGGGGGTAAGGGGAAGAAGGGAGCGGCCGGGCGCAAGGTCGGCGGGCCAAGGAAGAAGTCGGTGTCGAGGTCCGTGAAGGCCGGGCTCCAGTTCCCCGTCGGCCGCATCGGGCGCTACTTGAAGAAGGGCCGCTACGCGCAGCGTGTCGGCACCGGCGCCCCCGTCTACCTCGCCGCTGTCCTCGAATACCTCGCCGCTGAGGTTCTGGAGCTCGCCGGTAATGCTGCCAGGGACAACAAGAAGACTCGCATTATTCCGCGCCACGTGCTTCTGGCGATCCGGAACGACGAGGAGCTTGGGAAGCTGTTGGGCGGCGTGACTATCGCTCACGGCGGTGTGCTCCCCAATATCAACCCTGTTCTGCTGCCCAAGAAGACGGCGGAGAAGGCGTCCAGTGTGGGGAGCAAGGAGGCAAAGTCGCCCAAGAAGGCCGCCAAGTCCCCCAAGAAGGCATAGACTGACTGTCTGGAGTGATCTGATGTTTAGCAGGACCTTGATACCAGTATGCGGTGATGCGTAGGCTGTAGATGGGTCGAATGTGCTTGTGTGTGTATGTGCCCTGCTGCAAGTTGCCCTTTGCTATTTAAAATGGAAGAAGAAATGCCTTGTTTCTCTGAGGTTGCAATGTCTTTTCCCTGATTTCATTTCTGCACAGCTGTGATTTGTGATATTCAACCTGGGCGACACTGTTTACTGAGATTTTCGATTAGAATTTGCTGTGCCAGAAAATATGCAAATGCGGTAGAACGGTGGATTGTTCTTTACTT - >Zm00001eb397500_T002
ACTTTCCCATCAACTCGCAATTCCGCATTCGTTCCAACTCCTGAGCACTTTCTCCTCGTCCCCGACAAGCCAATCGAAGCCGAGATACGGCCATGGACTCCACCGGCACCGGAGCAGGGGGTAAGGGGAAGAAGGGAGCGGCCGGGCGCAAGGTCGGCGGGCCAAGGAAGAAGTCGGTGTCGAGGTCCGTGAAGGCCGGGCTCCAGTTCCCCGTCGGCCGCATCGGGCGCTACTTGAAGAAGGGCCGCTACGCGCAGCGTGTCGGCACCGGCGCCCCCGTCTACCTCGCCGCTGTCCTCGAATACCTCGCCGCTGAGGTTCTGGAGCTCGCCGGTAATGCTGCCAGGGACAACAAGAAGACTCGCATTATTCCGCGCCACGTGCTTCTGGCGATCCGGAACGACGAGGAGCTTGGGAAGCTGTTGGGCGGCGTGACTATCGCTCACGGCGGTGTGCTCCCCAATATCAACCCTGTTCTGCTGCCCAAGAAGACGGCGGAGAAGGCGTCCAGTGTGGGGAGCAAGGAGGCAAAGTCGCCCAAGAAGGCCGCCAAGTCCCCCAAGAAGGCATAGACTGACTGTCTGGAGTGATCTGATGTTTAGCAGGACCTTGATACCAGTATGCGGTGATGCGTAGGCTGTAGATGGGTCGAATGTGCTTGTGTGTGTATGTGCCCTGCTGCAAGTTGCCCTTTGCTATTTAAAATGGAAGAAGAAATGCCTTGTTTCTCTGAGGTTGCAATGTCTTTTCCCTGATTTCATTTCTGCACAGCTGTGATTTGTGATATTCAACCTGGGCGACACTGTTTACTGAGATTTTCGATTAGAATTTGCTGTGCCAGAAAATATGCAAATGCGGTAGAACGGTGGATTGTTCTTTACTT
CDS Sequence
- >Zm00001eb397500_T001
ATGGACTCCACCGGCACCGGAGCAGGGGGTAAGGGGAAGAAGGGAGCGGCCGGGCGCAAGGTCGGCGGGCCAAGGAAGAAGTCGGTGTCGAGGTCCGTGAAGGCCGGGCTCCAGTTCCCCGTCGGCCGCATCGGGCGCTACTTGAAGAAGGGCCGCTACGCGCAGCGTGTCGGCACCGGCGCCCCCGTCTACCTCGCCGCTGTCCTCGAATACCTCGCCGCTGAGGTTCTGGAGCTCGCCGGTAATGCTGCCAGGGACAACAAGAAGACTCGCATTATTCCGCGCCACGTGCTTCTGGCGATCCGGAACGACGAGGAGCTTGGGAAGCTGTTGGGCGGCGTGACTATCGCTCACGGCGGTGTGCTCCCCAATATCAACCCTGTTCTGCTGCCCAAGAAGACGGCGGAGAAGGCGTCCAGTGTGGGGAGCAAGGAGGCAAAGTCGCCCAAGAAGGCCGCCAAGTCCCCCAAGAAGGCATAG - >Zm00001eb397500_T002
ATGGACTCCACCGGCACCGGAGCAGGGGGTAAGGGGAAGAAGGGAGCGGCCGGGCGCAAGGTCGGCGGGCCAAGGAAGAAGTCGGTGTCGAGGTCCGTGAAGGCCGGGCTCCAGTTCCCCGTCGGCCGCATCGGGCGCTACTTGAAGAAGGGCCGCTACGCGCAGCGTGTCGGCACCGGCGCCCCCGTCTACCTCGCCGCTGTCCTCGAATACCTCGCCGCTGAGGTTCTGGAGCTCGCCGGTAATGCTGCCAGGGACAACAAGAAGACTCGCATTATTCCGCGCCACGTGCTTCTGGCGATCCGGAACGACGAGGAGCTTGGGAAGCTGTTGGGCGGCGTGACTATCGCTCACGGCGGTGTGCTCCCCAATATCAACCCTGTTCTGCTGCCCAAGAAGACGGCGGAGAAGGCGTCCAGTGTGGGGAGCAAGGAGGCAAAGTCGCCCAAGAAGGCCGCCAAGTCCCCCAAGAAGGCATAG
Protein Sequence
- >Zm00001eb397500_P001
MDSTGTGAGGKGKKGAAGRKVGGPRKKSVSRSVKAGLQFPVGRIGRYLKKGRYAQRVGTGAPVYLAAVLEYLAAEVLELAGNAARDNKKTRIIPRHVLLAIRNDEELGKLLGGVTIAHGGVLPNINPVLLPKKTAEKASSVGSKEAKSPKKAAKSPKKA - >Zm00001eb397500_P002
MDSTGTGAGGKGKKGAAGRKVGGPRKKSVSRSVKAGLQFPVGRIGRYLKKGRYAQRVGTGAPVYLAAVLEYLAAEVLELAGNAARDNKKTRIIPRHVLLAIRNDEELGKLLGGVTIAHGGVLPNINPVLLPKKTAEKASSVGSKEAKSPKKAAKSPKKA
Source: Genetic information comes from the article