Information report for Wox3;Wox3a
Gene Details
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Functional Descriptions
- The planar, mediolateral outgrowth of both eudicot and monocot leaves is dependent on conserved Wuschel-like homeobox3 (Wox3) transcription-factor-encoding genes2,3,4. As described previously, Wox3 genes are expressed in the marginal domain of the SAM peripheral zone and at the intersection of the adaxial–abaxial (top–bottom) domains (that is, the rim1) of developing leaf primordial edges, where they promote mediolateral outgrowth of the marginal leaf domain.
- We show that rim function is regulated by genetically redundant Wuschel-like homeobox3 (Wox3) transcription factors. Higher-order mutations in maize Wox3 genes greatly reduce leaf width and disrupt ligule outgrowth and patterning.
- We refer to this edge-most region of Wox3 expression as the leaf primordial rim domain.
- Wox3 mutants perturb the marginal and lateral leaf domains.
- Higher-order Wox3 function and ligule development.
Functional Keywords
Literature and News
Gene Resources
- NCBI ID: LOC100127511
- UniProt accessions: Q70UV1
- EMBL: AJ536578
- AlphaFoldDB: Q70UV1
- EnsemblPlants: Zm00001eb092480_T001
- Gramene: Zm00001eb092480_T001
- KEGG: zma:542051
- OMA: HQQPEEW
- ExpressionAtlas: Zm00001eb092480
- InterPro: IPR001356 , IPR009057 , IPR044555
- PANTHER: PTHR45940 , PTHR45940:SF42
- SUPFAM: SSF46689
- PROSITE: PS50071
- Gene3D: 1.10.10.60
- OrthoDB: Q70UV1
- SMR: Q70UV1
- CDD: cd00086
Homologs
- Brachypodium distachyon: Bradi2g37650.1.p
- Panicum virgatum: Pavir.3KG116800.2.p, Pavir.3KG116800.1.p, Pavir.3KG119400.1.p
- Setaria italica: Seita.3G043800.1.p
- Setaria viridis: Sevir.3G044600.1.p
- Triticum aestivum: Traes_1DS_E50CDDF05.1, Traes_1BS_C908081B8.1
Sequences
cDNA Sequence
- >Zm00001eb265710_T001
GTCTAAACTCAACTCCTACGATGGTGGTGGTGGTGGGCATGTGCGCGTGTATGTATAGTGTCTTCTGCATCCATTATATATACTGTGCAGACAGGAAGAAGGAAGCAGTAGTGGCCGGCCTCTCCCCACTACATGCTTCTTCGTCGTCTCATCCTCTTCTTCCAATCCAGACCTCCGTCCACACCCACCCATCTGCTCCTCCTCCTCCTCCCTCCCTAGTACCCATTTTGTCTCTCTCAACAGTCCCTCTCTCTCCAGTCTCCACACACCCAACCAACCAAACCAAACCAAACCAAAACCTTTTTGCTAGCTTATTCACAGACAGCAGCTTCCAACCAATCAAACTCATCGACCGATCGAGTGCTCGTACACCAATAGCTCAGCCAGCCATCAAATCCTAGCTGGAGGTGCGTACGTACTTGGCTAGAGGAGGTAGACGACGACGGCGACGACGACCGACATGCCGTCGCAGCAGCAGCAGCAGCAGGGCCAGCAGGTGGCGGCGGGGTCGACGCGGTGGTGCCCGACGCCGGAGCAGCTGATGATCCTGGAGGACATGTACCGCGGCGGCCTGCGCACGCCCAACGCGTCGCAGATCCAGCAGATCACGGCGCACCTCGCCTGCTACGGCCGCATCGAGGGCAAGAACGTCTTCTACTGGTTCCAGAACCACAAGGCCCGGGACCGCCAGAAGATGCGCCGCAGGCTCTGCATGAGCCACCACCTCCTCTCCTGCGCGCAGTACTACGCCGCGGCGGCGCACCACGGCCACGCCGCCTTCCTCGCCGCGCCGCCGCCGTACGGGCACCAGCTGCTCTCCCCGTCCACGACGTCGCCCACCCCGGCTGCTGCTGCTGCTGCCGCCGCTGCAGCGTACGGCTACTACTACCCCGCCACGGCCGCCTTCGCTGCACCGGCGAGCCGGTGCGCCGGCAACGCCACTCCCCCGTCGCCGACCACCCAGCTGTTCCACTATCAGGGTGGCGGAGGGCTTGTGCCGACGGAGGCGCTCGGCCGGCCGGAGTACTCGCTGGGGAAGCTGGACAACTTCGGCGTGGCGCTTGACGACGTCGTGGTGAGCTCGACCTCCGGTGCTGTCGTCGACACGATGGGGGCGCCTCCGGTTGCAGGGTTCGAGGTGGCGCCGCCGCTGCCGGCTGCCTTCAGCTGCCGGCCGCTCAAGACGCTAGACCTCTTCCCCGGCGGTCTCGAGGAAGAGCAGCACGACGTGGCCTGATCGGCGCATATATGCCGTTGTTACCATTAATTACTACTTAGCTAGTCGTCGCCATCAGTCGTTGATGCATGTCAATGTCATGCAGTAGTACGTAGTACACACACGCTGACATGATCTCAGCTCGTCCCCCTCCCGATCAATTTAGCTGGAGCTACGACAGCTAGAGCTAGCTTCGTTCTGATCTCTCTCCGATCCATGGCTACAATCTAGTGTGTCGTCGTCGTGTTGTTCTTTCTGATGCATGTGTTTGGTTAGAGGGTGTACTTACTCGTTTCTAGAGATTAGTGCGCTCTGGCTAGCAGCTAGCTAGAGAGGAGAGGGAGTGGGCGCTGAGCAGCAAGAGCTAGCTAGGAGTACAGTAGTACGTGCTACTAGAGTAGAAGAGGCCCACCGGGGAGGCACAGGCACAGAGCAGTCTGCGATGCATTCATTCCTTGTTGAGTTATTATGGGATGTGACCGTGCGTACAGTGCGTGTTTAGTGTAGCTAAAACAGGCATGCATGCAGTGTGAAGCTACTATAGCTGGTGGGGGGTACGGTACCTACTAACTAGGCTTTATTTGCAGAGCTCATTACTGGTGGGAGAGGAGATCAAACTTAGGTTCATGAATATCATGTAATGGAATGTTCCTTGCTTGCCGGTCCCCCAACTCCCAACCTCCACCAATTCCTCTCTCTCACTCTCTCTCTCTCTCGCATCTAGATCAAGATCCCTCCTGCTCCACACCCTGTGTCGCTCCGTGTGTATGGACTTTTCTTTTGCCTGCCTT
CDS Sequence
- >Zm00001eb265710_T001
ATGCCGTCGCAGCAGCAGCAGCAGCAGGGCCAGCAGGTGGCGGCGGGGTCGACGCGGTGGTGCCCGACGCCGGAGCAGCTGATGATCCTGGAGGACATGTACCGCGGCGGCCTGCGCACGCCCAACGCGTCGCAGATCCAGCAGATCACGGCGCACCTCGCCTGCTACGGCCGCATCGAGGGCAAGAACGTCTTCTACTGGTTCCAGAACCACAAGGCCCGGGACCGCCAGAAGATGCGCCGCAGGCTCTGCATGAGCCACCACCTCCTCTCCTGCGCGCAGTACTACGCCGCGGCGGCGCACCACGGCCACGCCGCCTTCCTCGCCGCGCCGCCGCCGTACGGGCACCAGCTGCTCTCCCCGTCCACGACGTCGCCCACCCCGGCTGCTGCTGCTGCTGCCGCCGCTGCAGCGTACGGCTACTACTACCCCGCCACGGCCGCCTTCGCTGCACCGGCGAGCCGGTGCGCCGGCAACGCCACTCCCCCGTCGCCGACCACCCAGCTGTTCCACTATCAGGGTGGCGGAGGGCTTGTGCCGACGGAGGCGCTCGGCCGGCCGGAGTACTCGCTGGGGAAGCTGGACAACTTCGGCGTGGCGCTTGACGACGTCGTGGTGAGCTCGACCTCCGGTGCTGTCGTCGACACGATGGGGGCGCCTCCGGTTGCAGGGTTCGAGGTGGCGCCGCCGCTGCCGGCTGCCTTCAGCTGCCGGCCGCTCAAGACGCTAGACCTCTTCCCCGGCGGTCTCGAGGAAGAGCAGCACGACGTGGCCTGA
Protein Sequence
- >Zm00001eb265710_P001
MPSQQQQQQGQQVAAGSTRWCPTPEQLMILEDMYRGGLRTPNASQIQQITAHLACYGRIEGKNVFYWFQNHKARDRQKMRRRLCMSHHLLSCAQYYAAAAHHGHAAFLAAPPPYGHQLLSPSTTSPTPAAAAAAAAAAYGYYYPATAAFAAPASRCAGNATPPSPTTQLFHYQGGGGLVPTEALGRPEYSLGKLDNFGVALDDVVVSSTSGAVVDTMGAPPVAGFEVAPPLPAAFSCRPLKTLDLFPGGLEEEQHDVA