Gene Details:
- Gene ID: GRMZM2G372364
- Gene Symbol: ZmCLE7
- Gene Name: clavata3/esr-related7
- Genome: B73_RefGen_v3
- Species: Zea mays
Functional Descriptions:
- CRISPR–Cas9 to edit maize CLE promoters and a newly characterized maize CLE gene identified through its compensatory upregulation in a ZmCLE7 mutant.
- This inversion allele led to an expanded expression of ZmCLE7 in developing ear primordia, from the normal epidermal-enriched expression towards the centre of the IM.
- As ZmCLE7 and ZmFCP1 control meristem size, we observed roughly 5mm stage developing ear primordia in a subset of the alleles.
- ZmCLE7 promoter-edited alleles as heterozygotes with a null allele increase IM size.
- At harvest, the fasciated ears of ZmCLE7 null alleles are highly disorganized and shorter with much lower grain yield.
Function-related keywords:
- grain , grain-size , grain-yield , yield , meristem
Literature:
- Enhancing grain-yield-related traits by CRISPR-Cas9 promoter editing of maize CLE genes. DOI: 10.1038/s41477-021-00858-5 ; PMID: 33619356
Related News:
Gene Resources:
- NCBI ID: LOC103652804
- UniProt accessions: A0A1D6F995
Orthologs:
Sequences:
cDNA Sequence
- >Zm00001eb117820_T002
TTCACACAGGGGCAGAGGGCGGTCGCGCACACCTTTCCCTTCCCCCCTCTCGTTCCCCTCTCCTTCCCATTAATATCTAGCCGCACCTTCCCTCTCTCACCTCCTCATCCTCCTCCAACTGTGAGCGTACGTTCCACGGCCGCCGCCATTAGTGTTGAGAGAGGGAGAGAAGCTACAGGGACCGGACGCCTCCTTCCTTGCTGACCGGCGAGCTTTATTTTCAGGCCCCTCGCTCGCTAGGGTTCCATCATCCCGCCCGCTGTTCCTTTTCGTCCATGGATCAGAACTTCGGGAACCTCGGGACCGGAGCCGGGAGCAGCGGCGGGTGCGGGGGCTCCAACTCCAACTCCAAGGCGGTGGCGGCGGTGTCGTCCTCGTCCTTCCTGCAGCTGCCGCTGTCGACGGCGGCGGCGGCGTCCCCCGCGTACTACGGCGCGCCGCTCGCGCTCCTGCACCACGGCACCACCGCGGGCCCGTCGTCGTCGCAGCAGCAGCAGCACCAGTCGCCGTACGCCAAGCACGGCGCCGAGATGTCGGCGGCGGAGGCCGACGCCATAAAGGCCAAGATCGTGGCGCACCCGCAGTACTCGGCGCTCCTCGCCGCCTACCTCGACTGCCAGAAAGTGGGCGCGCCGCCGGACCTGCTGGAGAGGCTGACGGCCATGGCGGCGAAGCTGGACGCGCGCCCGCCGGGCCGCCACGGGCCGCGCGACCCGGAGCTGGACCAGTTCATGGAGGCGTACTGCAACATGCTCGTCAAGTACCGGGAGGAGCTGACCCGGCCGATCGACGAGGCCATGGAGTTCCTCAAGCGGGTGGAGGCGCAGCTCGACTCCATCGCCGGCGGCGGCTCCTCCTCCTCCGCGCGCCTCTCGCTCGCCGGCGGCAGCCCAGCGTGGTCGAAACTGACGAGACACTTTGAAATTCGACGACGACAGAACAAAACCTCTGGCTGGAAAGTGGAAACACGTGACCTTACCAAAAGCTCCTCTCTTTTTTTTTTCTTCTTCTTCTGCAGATGGTAAGTCATCAGAAGGGGCCGGCTCTTCGGAAGACGACGACATGGATCCGAGCGGCCGCGAGAACGAGCCGCCGGAGATCGACCCGCGCGCGGAGGACAAGGAGCTCAAGTACCAGCTCCTGAAGAAGTACAGCGGGTACCTGAGCAGCCTGAGGCAGGAGTTCTCCAAGAAGAAGAAGAAAGGGAAGCTGCCGAAGGAGGCCAGGCAGAAGCTCCTCCACTGGTGGGAGCTGCACTACAAGTGGCCGTACCCTTCGGAGACGGAGAAGATCGCGCTGGCAGAGGCGACTGGCCTGGACCAGAAGCAGATCAACAACTGGTTCATCAACCAGCGGAAGCGGCACTGGAAGCCGTCGGAGGACATGCCATTCGTCATGATGGAAGGCTTCCACCCGCAGACCGCGGCCGCGCTGTACCTGGACGGCGGCGCGTTCATGGCCGACGGCATGACGACGTATCGCCTCGGTTCATGAACCGCCGTGGACAATCCAAAACCACCGGGCGACCGTGTCGGAGTGTTTCTGCGTACCAGGAAGATGCGATGCGAGGGACGTTGTTAATTATGGGGGGGTTTTGCTGCCGGTTTCCGCGCTGATCGCCACCAACCAAGGCGGGGTGCGGTCAGTGATCTAGTGGCG - >Zm00001eb117820_T001
TTCACACAGGGGCAGAGGGCGGTCGCGCACACCTTTCCCTTCCCCCCTCTCGTTCCCCTCTCCTTCCCATTAATATCTAGCCGCACCTTCCCTCTCTCACCTCCTCATCCTCCTCCAACTGTGAGCGTACGTTCCACGGCCGCCGCCATTAGTGTTGAGAGAGGGAGAGAAGCTACAGGGACCGGACGCCTCCTTCCTTGCTGACCGGCGAGCTTTATTTTCAGGCCCCTCGCTCGCTAGGGTTCCATCATCCCGCCCGCTGTTCCTTTTCGTCCATGGATCAGAACTTCGGGAACCTCGGGACCGGAGCCGGGAGCAGCGGCGGGTGCGGGGGCTCCAACTCCAACTCCAAGGCGGTGGCGGCGGTGTCGTCCTCGTCCTTCCTGCAGCTGCCGCTGTCGACGGCGGCGGCGGCGTCCCCCGCGTACTACGGCGCGCCGCTCGCGCTCCTGCACCACGGCACCACCGCGGGCCCGTCGTCGTCGCAGCAGCAGCAGCACCAGTCGCCGTACGCCAAGCACGGCGCCGAGATGTCGGCGGCGGAGGCCGACGCCATAAAGGCCAAGATCGTGGCGCACCCGCAGTACTCGGCGCTCCTCGCCGCCTACCTCGACTGCCAGAAAGTGGGCGCGCCGCCGGACCTGCTGGAGAGGCTGACGGCCATGGCGGCGAAGCTGGACGCGCGCCCGCCGGGCCGCCACGGGCCGCGCGACCCGGAGCTGGACCAGTTCATGGAGGCGTACTGCAACATGCTCGTCAAGTACCGGGAGGAGCTGACCCGGCCGATCGACGAGGCCATGGAGTTCCTCAAGCGGGTGGAGGCGCAGCTCGACTCCATCGCCGGCGGCGGCTCCTCCTCCTCCGCGCGCCTCTCGCTCGCCGGCGGCAGCCCAGCGTGGTCGAAACTGACGAGACACTTTGAAATTCGACGACGACAGAACAAAACCTCTGGCTGGAAAGTGGAAACACGTGACCTTACCAAAAGCTCCTCTCTTTTTTTTTTCTTCTTCTTCTGCAGATGGTAAGTCATCAGAAGGGGCCGGCTCTTCGGAAGACGACGACATGGATCCGAGCGGCCGCGAGAACGAGCCGCCGGAGATCGACCCGCGCGCGGAGGACAAGGAGCTCAAGTACCAGCTCCTGAAGAAGTACAGCGGGTACCTGAGCAGCCTGAGGCAGGAGTTCTCCAAGAAGAAGAAGAAAGGGAAGCTGCCGAAGGAGGCCAGGCAGAAGCTCCTCCACTGGTGGGAGCTGCACTACAAGTGGCCGTACCCTTCGGAGACGGAGAAGATCGCGCTGGCAGAGGCGACTGGCCTGGACCAGAAGCAGATCAACAACTGGTTCATCAACCAGCGGAAGCGGCACTGGAAGCCGTCGGAGGACATGCCATTCGTCATGATGGAAGGCTTCCACCCGCAGACCGCGGCCGCGCTGTACCTGGACGGCGGCGCGTTCATGGCCGACGGCATGACGACGTATCGCCTCGGTTCATGAACCGCCGTGGACAATCCAAAACCACCGGGCGACCGTGTCGGAGTGTTTCTGCGTACCAGGAAGATGCGATGCGAGGGACGTTGTTAATTATGGGGGGGTTTTGCTGCCGGTTTCCGCGCTGATCGCCACCAACCAAGGCGGGGTGCGGTCAGTGATCTAGTGGCG
CDS Sequence
- >Zm00001eb117820_T002
ATGGATCAGAACTTCGGGAACCTCGGGACCGGAGCCGGGAGCAGCGGCGGGTGCGGGGGCTCCAACTCCAACTCCAAGGCGGTGGCGGCGGTGTCGTCCTCGTCCTTCCTGCAGCTGCCGCTGTCGACGGCGGCGGCGGCGTCCCCCGCGTACTACGGCGCGCCGCTCGCGCTCCTGCACCACGGCACCACCGCGGGCCCGTCGTCGTCGCAGCAGCAGCAGCACCAGTCGCCGTACGCCAAGCACGGCGCCGAGATGTCGGCGGCGGAGGCCGACGCCATAAAGGCCAAGATCGTGGCGCACCCGCAGTACTCGGCGCTCCTCGCCGCCTACCTCGACTGCCAGAAAGTGGGCGCGCCGCCGGACCTGCTGGAGAGGCTGACGGCCATGGCGGCGAAGCTGGACGCGCGCCCGCCGGGCCGCCACGGGCCGCGCGACCCGGAGCTGGACCAGTTCATGGAGGCGTACTGCAACATGCTCGTCAAGTACCGGGAGGAGCTGACCCGGCCGATCGACGAGGCCATGGAGTTCCTCAAGCGGGTGGAGGCGCAGCTCGACTCCATCGCCGGCGGCGGCTCCTCCTCCTCCGCGCGCCTCTCGCTCGCCGGCGGCAGCCCAGCGTGGTCGAAACTGACGAGACACTTTGAAATTCGACGACGACAGAACAAAACCTCTGGCTGGAAAGTGGAAACACGTGACCTTACCAAAAGCTCCTCTCTTTTTTTTTTCTTCTTCTTCTGCAGATGGTAA - >Zm00001eb117820_T001
ATGGATCAGAACTTCGGGAACCTCGGGACCGGAGCCGGGAGCAGCGGCGGGTGCGGGGGCTCCAACTCCAACTCCAAGGCGGTGGCGGCGGTGTCGTCCTCGTCCTTCCTGCAGCTGCCGCTGTCGACGGCGGCGGCGGCGTCCCCCGCGTACTACGGCGCGCCGCTCGCGCTCCTGCACCACGGCACCACCGCGGGCCCGTCGTCGTCGCAGCAGCAGCAGCACCAGTCGCCGTACGCCAAGCACGGCGCCGAGATGTCGGCGGCGGAGGCCGACGCCATAAAGGCCAAGATCGTGGCGCACCCGCAGTACTCGGCGCTCCTCGCCGCCTACCTCGACTGCCAGAAAGTGGGCGCGCCGCCGGACCTGCTGGAGAGGCTGACGGCCATGGCGGCGAAGCTGGACGCGCGCCCGCCGGGCCGCCACGGGCCGCGCGACCCGGAGCTGGACCAGTTCATGGAGGCGTACTGCAACATGCTCGTCAAGTACCGGGAGGAGCTGACCCGGCCGATCGACGAGGCCATGGAGTTCCTCAAGCGGGTGGAGGCGCAGCTCGACTCCATCGCCGGCGGCGGCTCCTCCTCCTCCGCGCGCCTCTCGCTCGCCGGCGGCAGCCCAGCGTGGTCGAAACTGACGAGACACTTTGAAATTCGACGACGACAGAACAAAACCTCTGGCTGGAAAGTGGAAACACGTGACCTTACCAAAAGCTCCTCTCTTTTTTTTTTCTTCTTCTTCTGCAGATGGTAA
Protein Sequence
- >Zm00001eb117820_P002
MDQNFGNLGTGAGSSGGCGGSNSNSKAVAAVSSSSFLQLPLSTAAAASPAYYGAPLALLHHGTTAGPSSSQQQQHQSPYAKHGAEMSAAEADAIKAKIVAHPQYSALLAAYLDCQKVGAPPDLLERLTAMAAKLDARPPGRHGPRDPELDQFMEAYCNMLVKYREELTRPIDEAMEFLKRVEAQLDSIAGGGSSSSARLSLAGGSPAWSKLTRHFEIRRRQNKTSGWKVETRDLTKSSSLFFFFFFCRW - >Zm00001eb117820_P001
MDQNFGNLGTGAGSSGGCGGSNSNSKAVAAVSSSSFLQLPLSTAAAASPAYYGAPLALLHHGTTAGPSSSQQQQHQSPYAKHGAEMSAAEADAIKAKIVAHPQYSALLAAYLDCQKVGAPPDLLERLTAMAAKLDARPPGRHGPRDPELDQFMEAYCNMLVKYREELTRPIDEAMEFLKRVEAQLDSIAGGGSSSSARLSLAGGSPAWSKLTRHFEIRRRQNKTSGWKVETRDLTKSSSLFFFFFFCRW
Source: Genetic information comes from the article