Gene Details:

• Gene ID: Zm00001eb317730
• Gene Symbol: Dek43
• Gene Name: DEFECTIVE KERNEL 43
• Genome: Zm-B73-REFERENCE-NAM-5.0
• Species: Zea mays

Functional Descriptions:

• Determined that DEK41 is only localized to the mitochondria and identified a splicing defect of nad4 intron 3 in the dek41 mutant.
• Dek43 is a P-type pentatricopeptide repeat (PPR) protein responsible for the Cis-splicing of nad4 in maize mitochondria.
• Dek43, a dual-localized PPR protein, plays an important role in maintaining mitochondrial function and maize kernel development.
• Mutations in Dek43 affect cis-splicing of mitochondrial nad4 introns 1 and 3.
• The Dek43-1 mutant exhibits reduced mitochondrial complex I abundance and activity.
• Dek43 mutations cause reduced splicing efficiency of mitochondrial nad4 intron 3, resulting in severely reduced complex I assembly and NADH dehydrogenase activity.

Function-related keywords:

• development ,  mitochondria ,  dehydrogenase

Literature:

• DEK43 is a P-type pentatricopeptide repeat (PPR) protein responsible for the Cis-splicing of nad4 in maize mitochondria.   DOI:  10.1111/jipb.12843 ;  PMID:  31119902
• Maize pentatricopeptide repeat protein DEK41 affects cis-splicing of mitochondrial nad4 intron 3 and is required for normal seed development.   DOI:  10.1093/jxb/erz193 ;  PMID:  31020318

Related News:

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Gene Resources:

• NCBI ID: 100285499
• UniProt accessions: B4FPH2

Sequences:

Source: Genetic information comes from the article