Gene Details:

• Gene ID: Zm00001eb251650
• Gene Symbol: ZmbHLH122 bHLH122
• Gene Name: bHLH-transcription factor 122
• Genome: Zm-B73-REFERENCE-NAM-5.0
• Species: Zea mays

Functional Descriptions:

• The bHLH transcription factors MS23, MS32, bHLH122 and bHLH51 are involved in anther somatic cell development in turn, and play an important role in regulating the proliferation of proper tapetum cells.
• MS23, MS32, bHLH122 and bHLH51 showed sterility after mutation of 4 transcription factors.
• The male-sterile ms23, ms32, and bHLH122-1 mutants lack 24-nt phased secondary small interfering RNAs (phasiRNAs) and the precursor transcripts from the corresponding 24-PHAS loci, while the bhlh51-1 mutant has wild-type levels of both precursors and small RNA products.
• Multiple lines of evidence suggest that 24-nt phasiRNA biogenesis primarily occurs downstream of MS23 and MS32, both of which directly activate Dcl5 and are required for most 24-PHAS transcription, with bHLH122 playing a distinct role in 24-PHAS transcription.

Function-related keywords:

• development ,  anther ,  sterility ,  tapetum ,  sterile ,  anther-development ,  cell-proliferation ,  male-sterility

Literature:

• A cascade of bHLH-regulated pathways programs maize anther development.   DOI:  10.1093/plcell/koac007 ;  PMID:  35018475
• CRISPR/Cas9-based discovery of maize transcription factors regulating male sterility and their functional conservation in plants.   DOI:  10.1111/pbi.13590 ;  PMID:  33772993

Related News:

• The Plant Cell | 斯坦福大学揭示玉米花药发育中bHLH调控途径的级联过程
• PBJ | 北京科技大学万向元团队利用CRISPR/Cas9批量化发掘玉米雄性不育转录因子并构建转录调控通路

Gene Resources:

• NCBI ID: 100282922
• UniProt accessions: A0A1D6HH16

Sequences:

Source: Genetic information comes from the article