Gene Details:

Functional Descriptions:

  • Ubiquitin ligase VvPUB26 in grapevine promotes proanthocyanidin synthesis and resistance to powdery mildew.
  • Overexpression of VvPUB26 in grapes leads to a significant increase in PAs content, whereas interfering with VvPUB26 has the opposite effect.
  • Overexpression of VvPUB26 in transgenic grapevines enhances defense against powdery mildew while interfering with VvPUB26 results in increased susceptibility to the pathogen.
  • Our results unveil a regulatory module involving VvPUB26-VvWRKY24-VvDFR/VvLAR that plays a fundamental role in governing PAs biosynthesis in grapevines.

Literature:

Gene Resources:

Orthologs:

Sequences:

cDNA Sequence
  • >Vitvi03g00519_t001
    GAAACAGGGACAATTAATAGAAGATGTAAACGTGAGTAAGATTTATGGAGGAAAGTGGGCCCAGTAGTCTCACCTTATTTTTGACCAAACTTTGCCAACTAGGGTTAGAGGTGAGTAAATGGAGACACACGTGTGAAGCAGAGTCAGAGATAAGGGGCAGAGTCCAGCCCAGTCCTACGGCTGTTGGTATGTCCCTCTGTTTCAAATCGTATAAGAGAAAGCAAAGAGTGAGAAAGTGAAAGAGAATTTGCAGTGAGCTCAGATATAGTATTGCTCGTCCTATTATAGAGAGAAAGAAAAAAATGCCTGGGAGTTTAGAGCCATTGGATGTGGGTGTTCAGATCCCATACCACTTCAGGTGTCCGATCTCGCTCGAGCTCATGTGTGACCCTGTCACCGTTAGCACGGGTCAGACCTACGACCGAGCCAGCATCGAGTACTGGGTCGGCACCGGCAACACCACCTGCCCCGTCACGCGGTCTTCTCTTACCGACTTCACCCTCATCCCCAACCACACCCTTCGCCGTCTCATCCAGGACTGGTGCGTTGCCAACCGGTCCTTTGGAGTTGAGCGTATTCCCACTCCCAAACAGCCTGCCGACCCAGCCTCGGTTCGGTCTCTGCAGACTCAGGTCTCTTCTCAGTCCAATCCTTCCCACACCAGGCTTTCGGCGGTGAAGCGACTCAGAGGACTCGCTCGTGACTCGGACAAAAACCGCTCTATCATTGGTTCGCATAATGTTCAGGAGGTTCTTCTCCCCGTTATTTTTTCGGATTCGGAGTGTGACTCGGCTGAGTTGAAGCATGAGTCACTCGCGCTTTTGGTGATGTTTCCTCTCTCTGAGTCGGAGTGCGCGTTCGTAGCGTCCCAGCCGGACCGAGTCGCGCATCTCGTGTCGCTCCTATTTCACGCATCGATCGAGGTTCGGGTCAACTCGGCCGCACTCATCGAGATCGTGGTCGCCGGAACCAGATCACTGGATCTCAGAGCTCAAATCAGCAATGTGGATGAAATCTTCGAAGGAATAACCGGAATTCTCAACTATCCATTGGCCTATCCTCGCGCGCTCAAAGTTGGAATCAAAGCCTTATTCGCCCTATGCCTGGCCAAGCAAAGCCGCCACAAGGCGGTCGCTGCCGGTGCTGTGACTGCTCTCATCGACCGATTGGCCGATTTTGAGAAGTGCGACGTGGAGCGAGCCCTGGCAACAGTGGAGCTGCTCTGCCGCGTTCCGGCGGGTTGCGCCGCCTTCGCAGCACACGCACTCACCGTGCCCCTCCTCGTGAGAAAAATTCTAAAAGTCTCCGACCGCGCAACGGAGTACGCTGCCGGAGCGCTGCTGTCGCTGTGCTCGGCGGCGGAGCAGAGCCAGAGAGAGGCGGTCTCCGCGGGGGTAGTGACTCAGCTTTTGCTGCTGGTACAAAGCGACTGTACGGAAAGAGCAAAGCGCAAAGCACAACTTTTGTTGAAGCTTCTTCGGGATTCGTGGCCAGAAGATTCGGTAGTCAATTCTGACGATTTTGGTTGCAGTGATGTTGTTCCATTTTGACGACGATGACCACGATCACACACATTCCATTCTTCTTCTTCCCCAATTCAAATCTCTATTCCATTTCACGAATTGCAGAGGGGAAAAAAAAAATGCAGCAAAATTGATTGTAGATCGGTATATAGGGAAATGTATTTGTGTATGTATGTATTTTTGTACGTAAGAATTTTTGTTGAAAGGCAAAGGAAAAGATAGATGTGATGTTAAATATGTGTTTTGTGGGGGCCATTAGTGTCTTAACTGTGATTAGTTTCAGACGAGGTGATATTTAGTTCGTCGGATGCATTGCATTATGCCATTATCCGCTACGCTCAATCTTGATTGGTCACCAATATGTTCTCACTTTGACCATTCTCTCACTACTTTTGCTTTTATTCATATATATATTTATATATTTTTCCG
CDS Sequence
  • >Vitvi03g00519_t001
    ATGCCTGGGAGTTTAGAGCCATTGGATGTGGGTGTTCAGATCCCATACCACTTCAGGTGTCCGATCTCGCTCGAGCTCATGTGTGACCCTGTCACCGTTAGCACGGGTCAGACCTACGACCGAGCCAGCATCGAGTACTGGGTCGGCACCGGCAACACCACCTGCCCCGTCACGCGGTCTTCTCTTACCGACTTCACCCTCATCCCCAACCACACCCTTCGCCGTCTCATCCAGGACTGGTGCGTTGCCAACCGGTCCTTTGGAGTTGAGCGTATTCCCACTCCCAAACAGCCTGCCGACCCAGCCTCGGTTCGGTCTCTGCAGACTCAGGTCTCTTCTCAGTCCAATCCTTCCCACACCAGGCTTTCGGCGGTGAAGCGACTCAGAGGACTCGCTCGTGACTCGGACAAAAACCGCTCTATCATTGGTTCGCATAATGTTCAGGAGGTTCTTCTCCCCGTTATTTTTTCGGATTCGGAGTGTGACTCGGCTGAGTTGAAGCATGAGTCACTCGCGCTTTTGGTGATGTTTCCTCTCTCTGAGTCGGAGTGCGCGTTCGTAGCGTCCCAGCCGGACCGAGTCGCGCATCTCGTGTCGCTCCTATTTCACGCATCGATCGAGGTTCGGGTCAACTCGGCCGCACTCATCGAGATCGTGGTCGCCGGAACCAGATCACTGGATCTCAGAGCTCAAATCAGCAATGTGGATGAAATCTTCGAAGGAATAACCGGAATTCTCAACTATCCATTGGCCTATCCTCGCGCGCTCAAAGTTGGAATCAAAGCCTTATTCGCCCTATGCCTGGCCAAGCAAAGCCGCCACAAGGCGGTCGCTGCCGGTGCTGTGACTGCTCTCATCGACCGATTGGCCGATTTTGAGAAGTGCGACGTGGAGCGAGCCCTGGCAACAGTGGAGCTGCTCTGCCGCGTTCCGGCGGGTTGCGCCGCCTTCGCAGCACACGCACTCACCGTGCCCCTCCTCGTGAGAAAAATTCTAAAAGTCTCCGACCGCGCAACGGAGTACGCTGCCGGAGCGCTGCTGTCGCTGTGCTCGGCGGCGGAGCAGAGCCAGAGAGAGGCGGTCTCCGCGGGGGTAGTGACTCAGCTTTTGCTGCTGGTACAAAGCGACTGTACGGAAAGAGCAAAGCGCAAAGCACAACTTTTGTTGAAGCTTCTTCGGGATTCGTGGCCAGAAGATTCGGTAGTCAATTCTGACGATTTTGGTTGCAGTGATGTTGTTCCATTTTGA
Protein Sequence
  • >Vitvi03g00519_P001
    MPGSLEPLDVGVQIPYHFRCPISLELMCDPVTVSTGQTYDRASIEYWVGTGNTTCPVTRSSLTDFTLIPNHTLRRLIQDWCVANRSFGVERIPTPKQPADPASVRSLQTQVSSQSNPSHTRLSAVKRLRGLARDSDKNRSIIGSHNVQEVLLPVIFSDSECDSAELKHESLALLVMFPLSESECAFVASQPDRVAHLVSLLFHASIEVRVNSAALIEIVVAGTRSLDLRAQISNVDEIFEGITGILNYPLAYPRALKVGIKALFALCLAKQSRHKAVAAGAVTALIDRLADFEKCDVERALATVELLCRVPAGCAAFAAHALTVPLLVRKILKVSDRATEYAAGALLSLCSAAEQSQREAVSAGVVTQLLLLVQSDCTERAKRKAQLLLKLLRDSWPEDSVVNSDDFGCSDVVPF