Gene Details:

Functional Descriptions:

  • VvBBX44 and VvMYBA1 form a regulatory feedback loop to balance anthocyanin biosynthesis in grape.
  • The expression of VvMYBA1 increased earlier than that of VvBBX44 during berry skin development, and exogenous anthocyanin treatment increased VvBBX44 expression.
  • VvMYBA1 directly activates VvUFGT and VvBBX44 expression. Although VvBBX44 does not physically interact with VvMYBA1, these two proteins form a feedback regulatory loop to balance anthocyanin biosynthesis in grapevine.
  • Our study highlights the regulatory roles of VvBBX44 and VvMYBA1 in anthocyanin biosynthesis and sheds light on a feedback regulatory loop that balances this process in grapes.
  • A regulatory gene, VvMYBA1, which could activate anthocyanin biosynthesis in a transient assay, was recently shown not to be transcribed in white berries due to the presence of a retrotransposon in the promoter.
  • Color recovery in berries of grape (Vitis vinifera L.) ‘Benitaka’, a bud sport of ‘Italia’, is caused by a novel allele at the VvMybA1 locus.
  • Expression analysis of VvMybA1 and genes in the anthocyanin biosynthesis pathway.
  • Found that the VvMybA1 locus of ‘Benitaka’ is heterozygous for the VvMybA1a allele (non-functional) and a novel VvMybA1BEN allele, and that VvMybA1BEN restored VvMybA1 transcripts.
  • These findings suggest that the expression of VvMybA1 is essential for the coloring of grape berry skin.

Literature:

Gene Resources:

Orthologs:

Sequences:

cDNA Sequence
  • >Vitvi02g01019_t001
    GTTGAGTTGACTCGATGGAGAGCTTAGGAGTTAGAAAGGGTGCATGGATCCAAGAAGAGGATGTTCTCCTGAGGAAATGCATTGAGAAATATGGAGAAGGAAAGTGGCATCTGGTTCCCCTCCGAGCAGGGTTGAATAGATGCCGAAAAAGCTGCAGGTTGAGATGGCTCAATTATTTGAAGCCGGATATCAAGAGAGGAGAGTTTGCATTAGACGAGGTTGATCTCATGATTAGGCTTCACAATTTGTTGGGGAACAGATGGTCCTTGATTGCGGGTAGGCTTCCAGGGAGGACTGCTAATGATGTCAAGAACTATTGGCATAGTCACCACTTCAAAAAGGAGGTTCAGTTCCAGGAAGAAGGGAGAGATAAACCCCAAACACATTCTAAAACCAAAGCTATAAAGCCTCACCCTCACAAGTTCTCCAAAGCCTTGCCAAGGTTTGAACTAAAAACTACAGCTGTGGATACTTTTGACACACAAGTCAGTACTTCCAGGAAGCCATCATCCACTTCACCACAACCGAATGATGACATCATATGGTGGGAAAGCCTGTTAGCTGAGCATGCTCAAATGGATCAAGAAACTGACTTTTCGGCTTCTGGAGAGATGCTTATCGCAAGCCTCAGGACAGAAGAAACTGCAACACAGAAAAAGGGACCCATGGATGGTATGATTGAACAAATCCAGGGAGGTGAGGGTGATTTTCCATTTGATGTGGGCTTCTGGGATACACCCAACACACAAGTAAATCACTTGATCTGA
CDS Sequence
  • >Vitvi02g01019_t001
    ATGGAGAGCTTAGGAGTTAGAAAGGGTGCATGGATCCAAGAAGAGGATGTTCTCCTGAGGAAATGCATTGAGAAATATGGAGAAGGAAAGTGGCATCTGGTTCCCCTCCGAGCAGGGTTGAATAGATGCCGAAAAAGCTGCAGGTTGAGATGGCTCAATTATTTGAAGCCGGATATCAAGAGAGGAGAGTTTGCATTAGACGAGGTTGATCTCATGATTAGGCTTCACAATTTGTTGGGGAACAGATGGTCCTTGATTGCGGGTAGGCTTCCAGGGAGGACTGCTAATGATGTCAAGAACTATTGGCATAGTCACCACTTCAAAAAGGAGGTTCAGTTCCAGGAAGAAGGGAGAGATAAACCCCAAACACATTCTAAAACCAAAGCTATAAAGCCTCACCCTCACAAGTTCTCCAAAGCCTTGCCAAGGTTTGAACTAAAAACTACAGCTGTGGATACTTTTGACACACAAGTCAGTACTTCCAGGAAGCCATCATCCACTTCACCACAACCGAATGATGACATCATATGGTGGGAAAGCCTGTTAGCTGAGCATGCTCAAATGGATCAAGAAACTGACTTTTCGGCTTCTGGAGAGATGCTTATCGCAAGCCTCAGGACAGAAGAAACTGCAACACAGAAAAAGGGACCCATGGATGGTATGATTGAACAAATCCAGGGAGGTGAGGGTGATTTTCCATTTGATGTGGGCTTCTGGGATACACCCAACACACAAGTAAATCACTTGATCTGA
Protein Sequence
  • >Vitvi02g01019_P001
    MESLGVRKGAWIQEEDVLLRKCIEKYGEGKWHLVPLRAGLNRCRKSCRLRWLNYLKPDIKRGEFALDEVDLMIRLHNLLGNRWSLIAGRLPGRTANDVKNYWHSHHFKKEVQFQEEGRDKPQTHSKTKAIKPHPHKFSKALPRFELKTTAVDTFDTQVSTSRKPSSTSPQPNDDIIWWESLLAEHAQMDQETDFSASGEMLIASLRTEETATQKKGPMDGMIEQIQGGEGDFPFDVGFWDTPNTQVNHLI