Gene Details:
- Gene ID: TraesCS7D02G296000.2
- Gene Symbol: TaSPO11-2-7D
- Gene Name: DNA topoisomerase
- Genome: Chinese_Spring1.0
- Species: Triticum aestivum
Functional Descriptions:
- SPO11.2 is essential for programmed double-strand break formation during meiosis in bread wheat.
- The three homoeologous SPO11-2 copies of hexaploid wheat exhibit high nucleotide and amino acid similarities with those of the diploids, tetraploids and Arabidopsis.
- We show that expression of the TaSPO11-2-7D copy restores fertility of Arabidopsis spo11-2 mutant demonstrating the strong functional conservation of the plant SPO11-2 gene.
- Cytological analyses of these mutants show synapsis defects, accompanied by severe reductions in bivalent formation and numbers of DMC1 foci, thus confirming the essential role of TaSPO11-2 in meiotic recombination in wheat.
Function-related keywords:
Literature:
- SPO11.2 is essential for programmed double-strand break formation during meiosis in bread wheat (Triticum aestivum L.). DOI: 10.1111/tpj.14903 ; PMID: 32603485
Related News:
Gene Resources:
- NCBI ID: KAF7109092
- UniProt accessions: A0A3B6TSG3
Orthologs:
Sequences:
cDNA Sequence
- >TraesCS7D02G296000.2
CCCGAGGAAGGAAGTGCGGTGCGGTGCGGATGGCGCAGGCGGAGGCGGACGTACCCGCAACCTCGCTCTTCGGTGCGGACCGCCGCCTCTGCTCAGCCGACGTGCTCTCGCCCCTCGAGGTTCGGGCAAGGATCGAGGTGGCGGTGCTCAATTTCCTCGCCACGCTCTCGTCTCCCTCTTCTCCGGCCATCCCTGTCCTCCCCCTGATCTCACGCAAGTCCACCAATTGCAGCCTGCGCAGCGGCTTGCTGAGTGATGTTTCATCGGTGTATCTGTCCTACGCCTTTTGCAAGAGGTCACTAATGAGAGAAAATGATGCCAAGGCATTCGTCAGAGTATGGAAAGTCATGGAGATGTGCTACAAGATCTTGGGCGAAGGGAAGCTTGTCACCCAGCGGGAGTTGTTCTACAAACTACTATCGGACTCACCCAAGTACTTCAGCTGTCAGCGCCATGTCAATCAAACCATCCAAGATGTTGTTTCATTGCTCCGTTGCACAAGGCAGAGTTTAGGAATCATGGCATCAAGTAGAGGGGCTCTGATTGGACGACTTGTGTTGCATGAACCGGAGGAAGAACACATTGATTGTTCCATTCTTGGACCTTCTGGGCATGCCATTACTGGGGATCTGAACCAATTGAGCAGATTAAATTTGTCTTCAGATGCCCGTTATCTCATTCTAGTGGAGAAGGATGCCATATTTCAGAGGCTGGCTGAAGACCGCTTATATAATCAGCTTCCATGTATCCTGATCACTGCAAAAGGATATCCTGATATCGCCACGAGGTTTATCTTGCATCGACTGAGCCAGACTTTTCCAAATATGCCAATATTTGCATTAGTGGACTGGAACCCTGCAGGGCTCTCTATACTGTGTACTTACAAATATGGAAGCATATCAATGGGCTTGGAATCATACAGATACGCTTGCAATGTAAAATGGCTTGGCCTAAGAGGAGATGATCTGCAACTTATCCCTCAGAGTGCATTCCAAGAGTTGAAACCTCGTGATTTGCAGATCGCCAAAAGCTTGCTGTCATCTAAGTTTCTACAGGACACGCACAGGGCGGAGTTGACGCGGATGGTGGAGACAGGCACTCGTGCTGAGATCGAAGCTCTCTACTGCCATGGATTTGATTTCCTGGGGAAGTTCATCGCCAGGAAGATTGTGCAGGGTGACTACATTTGACAGAGTGCAGCGTTACTTGCTTGTCTCGTTTTTTGTTCTCGGCTGCATGGCTCATTGTATGAGATTATGATTGCATGATATATTGCTCTCGTGCATAGGCACGTATATATGATGTAC
CDS Sequence
- >TraesCS7D02G296000.2
ATGGCGCAGGCGGAGGCGGACGTACCCGCAACCTCGCTCTTCGGTGCGGACCGCCGCCTCTGCTCAGCCGACGTGCTCTCGCCCCTCGAGGTTCGGGCAAGGATCGAGGTGGCGGTGCTCAATTTCCTCGCCACGCTCTCGTCTCCCTCTTCTCCGGCCATCCCTGTCCTCCCCCTGATCTCACGCAAGTCCACCAATTGCAGCCTGCGCAGCGGCTTGCTGAGTGATGTTTCATCGGTGTATCTGTCCTACGCCTTTTGCAAGAGGTCACTAATGAGAGAAAATGATGCCAAGGCATTCGTCAGAGTATGGAAAGTCATGGAGATGTGCTACAAGATCTTGGGCGAAGGGAAGCTTGTCACCCAGCGGGAGTTGTTCTACAAACTACTATCGGACTCACCCAAGTACTTCAGCTGTCAGCGCCATGTCAATCAAACCATCCAAGATGTTGTTTCATTGCTCCGTTGCACAAGGCAGAGTTTAGGAATCATGGCATCAAGTAGAGGGGCTCTGATTGGACGACTTGTGTTGCATGAACCGGAGGAAGAACACATTGATTGTTCCATTCTTGGACCTTCTGGGCATGCCATTACTGGGGATCTGAACCAATTGAGCAGATTAAATTTGTCTTCAGATGCCCGTTATCTCATTCTAGTGGAGAAGGATGCCATATTTCAGAGGCTGGCTGAAGACCGCTTATATAATCAGCTTCCATGTATCCTGATCACTGCAAAAGGATATCCTGATATCGCCACGAGGTTTATCTTGCATCGACTGAGCCAGACTTTTCCAAATATGCCAATATTTGCATTAGTGGACTGGAACCCTGCAGGGCTCTCTATACTGTGTACTTACAAATATGGAAGCATATCAATGGGCTTGGAATCATACAGATACGCTTGCAATGTAAAATGGCTTGGCCTAAGAGGAGATGATCTGCAACTTATCCCTCAGAGTGCATTCCAAGAGTTGAAACCTCGTGATTTGCAGATCGCCAAAAGCTTGCTGTCATCTAAGTTTCTACAGGACACGCACAGGGCGGAGTTGACGCGGATGGTGGAGACAGGCACTCGTGCTGAGATCGAAGCTCTCTACTGCCATGGATTTGATTTCCTGGGGAAGTTCATCGCCAGGAAGATTGTGCAGGGTGACTACATTTGA
Protein Sequence
- >TraesCS7D02G296000.2
MAQAEADVPATSLFGADRRLCSADVLSPLEVRARIEVAVLNFLATLSSPSSPAIPVLPLISRKSTNCSLRSGLLSDVSSVYLSYAFCKRSLMRENDAKAFVRVWKVMEMCYKILGEGKLVTQRELFYKLLSDSPKYFSCQRHVNQTIQDVVSLLRCTRQSLGIMASSRGALIGRLVLHEPEEEHIDCSILGPSGHAITGDLNQLSRLNLSSDARYLILVEKDAIFQRLAEDRLYNQLPCILITAKGYPDIATRFILHRLSQTFPNMPIFALVDWNPAGLSILCTYKYGSISMGLESYRYACNVKWLGLRGDDLQLIPQSAFQELKPRDLQIAKSLLSSKFLQDTHRAELTRMVETGTRAEIEALYCHGFDFLGKFIARKIVQGDYI