Gene Details:

• Gene ID: TraesCS7A02G376800.1
• Gene Symbol: TaTHI2-7A
• Gene Name: thiamine thiazole synthase
• Genome: Chinese_Spring1.0
• Species: Triticum aestivum

Functional Descriptions:

• TaTHI2 interacts with Ca2+-dependent protein kinase TaCPK5 to suppress virus infection by regulating ROS accumulation.
• The results indicated that the expression of TaTHI2 can functionally complement the THI4 knock-out mutant strain of S. cerevisiae, suggesting that TaTHI2 should have a similar function to THI4 in thiamine biosynthesis.
• Overexpression of TaTHI2 (TaTHI2-OE) inhibited CWMV infection, while TaTHI2 silencing enhanced viral infection in wheat. Interestingly, the membrane-localized TaTHI2 protein was increased during CWMV infection.
• TaTHI2 also interacted with the Ca2+-dependent protein kinase 5 (TaCPK5), which is localized in the plasma membrane, and promoted reactive oxygen species (ROS) production by repressing TaCPK5-mediated activity of the catalase protein TaCAT1.
• Our findings reveal a novel function of TaTHI2 in plant immunity and suggest its potential as a valuable gene for balancing disease resistance and wheat yield.

Function-related keywords:

• kinase ,  resistance ,  disease ,  disease-resistance ,  yield ,  immunity ,  protein-kinase ,  plasma-membrane ,  viral-resistance ,  reactive-oxygen-species ,  catalase ,  plant-immunity ,  virus ,  protein

Literature:

• TaTHI2 interacts with Ca(2+)-dependent protein kinase TaCPK5 to suppress virus infection by regulating ROS accumulation.   DOI:  10.1111/pbi.14270 ;  PMID:  38100262

Related News:

Gene Resources:

• NCBI ID: XM_044567543.1
• UniProt accessions: A0A3B6RMJ1

Orthologs:

Sequences: