Gene Details:

• Gene ID: TraesCS6B02G379500
• Gene Symbol: TaMKK5-6B
• Gene Name: Protein kinase domain-containing protein
• Genome: Chinese_Spring1.0
• Species: Triticum aestivum

Functional Descriptions:

• The mitogen-activated protein kinase kinase TaMKK5 mediates immunity via the TaMKK5–TaMPK3–TaERF3 module.
• The TaMKK5-6B transcript level was elevated after R. cerealis infection and was higher in resistant wheat genotypes compared to susceptible genotypes.
• Overexpressing TaMKK5-6B increased resistance to sharp eyespot and upregulated the expression of multiple defense-related genes in wheat, including the MAPK gene TaMPK3, the ethylene response factor gene TaERF3, the calcium-dependent protein kinase gene TaCPK7-D, the glutathione s-transferase-1 gene TaGST1, Defensin, and Chitinase 2, while TaMKK5 knock-down compromised the resistance and repressed the expression of these defense-related genes.
• TaMKK5-6B is a promising gene for breeding wheat cultivars that are resistant to sharp eyespot.

Function-related keywords:

• kinase ,  resistance ,  defense-response ,  defense ,  ethylene ,  immunity ,  r-protein ,  breeding ,  protein-kinase ,  calcium ,  resistant ,  ethylene-response ,  protein

Literature:

• The mitogen-activated protein kinase kinase TaMKK5 mediates immunity via the TaMKK5-TaMPK3-TaERF3 module.   DOI:  10.1093/plphys/kiab227 ;  PMID:  34015126

Related News:

Gene Resources:

• NCBI ID: KAF7086370
• UniProt accessions: A0A3B6PR98

Orthologs:

Sequences: