Information report for TaMKK5-6B
Gene Details
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Functional Descriptions
- The mitogen-activated protein kinase kinase TaMKK5 mediates immunity via the TaMKK5–TaMPK3–TaERF3 module.
- The TaMKK5-6B transcript level was elevated after R. cerealis infection and was higher in resistant wheat genotypes compared to susceptible genotypes.
- Overexpressing TaMKK5-6B increased resistance to sharp eyespot and upregulated the expression of multiple defense-related genes in wheat, including the MAPK gene TaMPK3, the ethylene response factor gene TaERF3, the calcium-dependent protein kinase gene TaCPK7-D, the glutathione s-transferase-1 gene TaGST1, Defensin, and Chitinase 2, while TaMKK5 knock-down compromised the resistance and repressed the expression of these defense-related genes.
- TaMKK5-6B is a promising gene for breeding wheat cultivars that are resistant to sharp eyespot.
Functional Keywords
- kinase , resistance , defense-response , defense , ethylene , immunity , r-protein , breeding , protein-kinase , calcium , resistant , ethylene-response , protein
Literature and News
Gene Resources
- NCBI ID: KAF7086370
- UniProt accessions: A0A3B6PR98
- EnsemblPlants: TraesCS6B02G379500.1
- Gramene: TraesCS6B02G379500.1
- GO: GO:0004674 , GO:0005524 , GO:0005737
- OMA: RISCVYK
- InterPro: IPR000719 , IPR008271 , IPR011009 , IPR017441 , IPR053235
- PANTHER: PTHR24361 , PTHR24361:SF823
- SUPFAM: SSF56112
- PROSITE: PS00107 , PS00108 , PS50011
- Gene3D: 1.10.510.10 , 3.30.200.20
- OrthoDB: A0A3B6PR98
- SMR: A0A3B6PR98
- CDD: cd06623
Sequences
cDNA Sequence
- >TraesCS6B02G379500.1
ACGGCTGCATCTCGCTCGGCTGAGCGAGCGAGCGAGCGAGCAGAGCTCCCTCCCTCCGTCTCTCCTCCCCGTCCCTTGGCCTCCCTCGCGGCTATAAAAAACACTCGCCTCCCTCCAATCCCTCTTCCCCGACCCGATCGATCCCACCCCCACCCCACCCCGCCCCATACGGCGACAATCGCCGACGCCGACCGATCCGGCCGCCGCGCGGAGCAGGGGAGGAGCCAGCCTCGCGTTTCGGGCCGGCCAGAGCGCGCGATGCGTCCGGGCGGGCCGCCGAACGCGCGGCCGGGCCTGCAGCAGCAGCAGCCCGGCACGCCGGGCCGGGCGCGGCGCCGGCCGGATCTCACGCTGCCGCTGCCCCAGCGCGACCTGACGTCGCTGGCCGTGCCGCTGCCGCTGCCCCCGCCCCCGTCCTCGGCGCCGTCGTCCACGTCGTCCTCGGGGTCGGGGTCGGGGTCGGGCGGCGCGTCGTCCATGCCCATGCCCATGTCCATGACCCCGCCCAACTCGGCCGGCTCCGCGCCGCCCGCCCCGCCGCCGCTGGGCGAGCTGGAGCGCGTGCGGCGCGTCGGGAGCGGCGCCGGCGGGACGGTGTGGCTGGTGCGGCACGCGCCCACGGGCCGGGCCTACGCGCTCAAGGTGCTCTACGGGCACCACGACGAGGCGGTCCGGCGGCAGATCACGCGGGAGATCGCCATCCTGCGCACCGCGGAGCACCCGTCCATCGTGCGCTGCCACGGCATGTACGAGCAGGCCGGCGAGCTGCAGATCCTGCTCGAGTACATGGACGGCGGGTCCCTGGACGGCCGGCGCATCGCGTCCGAGGCCTTCCTCGCCGACGTAGCGCGGCAGGTGCTGTCGGGGATCGCGTACCTCCACCGGCGCCACATCGTGCACCGCGACATCAAGCCGTCCAACCTGCTCATCGACTCGGGGCGGCGCGTGAAGATCGCCGACTTCGGGGTGGGGCGCATCCTGAACCAGACCATGGACCCCTGCAACTCCTCCGTGGGCACCATCGCGTACATGAGCCCCGAGCGCATCAACACGGACCTCAACGACGGCAACTACAACGGCTACGCCGGCGACATCTGGAGCTTCGGCCTCAGCATCCTCGAGTTCTACCTGGGCCGCTTCCCGCTGGGGGAGAACCTGGGGAAGCAGGGCGACTGGGCGGCGCTCATGTGCGCCATCTGCTACTCCGAGTCGCCGGCCGCCCCGCCCACGGCCTCCCCGGAGCTGCGGAGCTTCATCAGCTGCTGCCTCCAGAAGAACCCGGCGAAGCGGCCGTCGGCGGCGCAGCTGCTGCAGCACCGGTTCATCGCCTCGCCGCCGCAGCAGCAGCCGCAGGTCCTCGCCGCCCCGCCGTGCTGACGGCCCGCCCGCCGTAACCAAGTTAAATTCGGACGGATCATGGACGGACGGACGGACGGACGGACGGACGGTGGCCGGCGGCGAGACGCGGGATCTAGGGGGAGGAGGGGCGATCTGTCTTCTTCTTAGCCATTTTGGGAACTGAAGCCACCACCACAAATTTACCCATCCATCCCTCGGAGTCCTGTTGTTGCTGTCGCCCCCGAAATTAAGCTCAAGCTTTTTCTTTAGTTTCCGTTAATGTCAATTAAATGTTCTCCCCTCCAAATGATGATGATTCTGATTCTGATTCTGATGATGATGATATAATATGGGCCGTTAAGAAAT
CDS Sequence
- >TraesCS6B02G379500.1
ATGCGTCCGGGCGGGCCGCCGAACGCGCGGCCGGGCCTGCAGCAGCAGCAGCCCGGCACGCCGGGCCGGGCGCGGCGCCGGCCGGATCTCACGCTGCCGCTGCCCCAGCGCGACCTGACGTCGCTGGCCGTGCCGCTGCCGCTGCCCCCGCCCCCGTCCTCGGCGCCGTCGTCCACGTCGTCCTCGGGGTCGGGGTCGGGGTCGGGCGGCGCGTCGTCCATGCCCATGCCCATGTCCATGACCCCGCCCAACTCGGCCGGCTCCGCGCCGCCCGCCCCGCCGCCGCTGGGCGAGCTGGAGCGCGTGCGGCGCGTCGGGAGCGGCGCCGGCGGGACGGTGTGGCTGGTGCGGCACGCGCCCACGGGCCGGGCCTACGCGCTCAAGGTGCTCTACGGGCACCACGACGAGGCGGTCCGGCGGCAGATCACGCGGGAGATCGCCATCCTGCGCACCGCGGAGCACCCGTCCATCGTGCGCTGCCACGGCATGTACGAGCAGGCCGGCGAGCTGCAGATCCTGCTCGAGTACATGGACGGCGGGTCCCTGGACGGCCGGCGCATCGCGTCCGAGGCCTTCCTCGCCGACGTAGCGCGGCAGGTGCTGTCGGGGATCGCGTACCTCCACCGGCGCCACATCGTGCACCGCGACATCAAGCCGTCCAACCTGCTCATCGACTCGGGGCGGCGCGTGAAGATCGCCGACTTCGGGGTGGGGCGCATCCTGAACCAGACCATGGACCCCTGCAACTCCTCCGTGGGCACCATCGCGTACATGAGCCCCGAGCGCATCAACACGGACCTCAACGACGGCAACTACAACGGCTACGCCGGCGACATCTGGAGCTTCGGCCTCAGCATCCTCGAGTTCTACCTGGGCCGCTTCCCGCTGGGGGAGAACCTGGGGAAGCAGGGCGACTGGGCGGCGCTCATGTGCGCCATCTGCTACTCCGAGTCGCCGGCCGCCCCGCCCACGGCCTCCCCGGAGCTGCGGAGCTTCATCAGCTGCTGCCTCCAGAAGAACCCGGCGAAGCGGCCGTCGGCGGCGCAGCTGCTGCAGCACCGGTTCATCGCCTCGCCGCCGCAGCAGCAGCCGCAGGTCCTCGCCGCCCCGCCGTGCTGA
Protein Sequence
- >TraesCS6B02G379500.1.cds1
MRPGGPPNARPGLQQQQPGTPGRARRRPDLTLPLPQRDLTSLAVPLPLPPPPSSAPSSTSSSGSGSGSGGASSMPMPMSMTPPNSAGSAPPAPPPLGELERVRRVGSGAGGTVWLVRHAPTGRAYALKVLYGHHDEAVRRQITREIAILRTAEHPSIVRCHGMYEQAGELQILLEYMDGGSLDGRRIASEAFLADVARQVLSGIAYLHRRHIVHRDIKPSNLLIDSGRRVKIADFGVGRILNQTMDPCNSSVGTIAYMSPERINTDLNDGNYNGYAGDIWSFGLSILEFYLGRFPLGENLGKQGDWAALMCAICYSESPAAPPTASPELRSFISCCLQKNPAKRPSAAQLLQHRFIASPPQQQPQVLAAPPC