Gene Details:

• Gene ID: TraesCS5A02G391400
• Gene Symbol: TaSPO11-1-5A
• Gene Name: TaSPO11-1
• Genome: Chinese_Spring1.0
• Species: Triticum aestivum

Functional Descriptions:

• Bread wheat TaSPO11-1 exhibits evolutionarily conserved function in meiotic recombination across distant plant species.
• Although the wheat and Arabidopsis SPO11-1 proteins share only 55% identity and the partner proteins also differ, the TaSPO11-1-5D cDNA significantly restored the fertility of the Arabidopsis spo11-1 mutant, indicating a robust functional conservation of the SPO11-1 protein activity across distant plants.
• This excludes the possibility that TaSPO11-1 induces DSBs independently of SPO11-2 (non-plant organisms have a single SPO11 protein), and confirms the need for the MTOPVIB to form DSBs.
• We extend these comparisons in demonstrating the functionality and evolutionary conservation of wheat TaSPO11-1 through heterologous complementation of the corresponding Arabidopsis and rice mutant lines, i.e. across distant plant species.

Function-related keywords:

• fertility ,  meiotic ,  meiotic-recombination ,  recombination ,  protein

Literature:

• Bread wheat TaSPO11-1 exhibits evolutionarily conserved function in meiotic recombination across distant plant species.   DOI:  10.1111/tpj.14882 ;  PMID:  32559326

Related News:

Gene Resources:

• NCBI ID:
• UniProt accessions: A0A3B6KM14

Orthologs:

Sequences: