Gene Details:

  • Gene ID:
  • Gene Symbol: TmMla1
  • Gene Name: Mla homologue 1
  • Genome: Chinese_Spring1.0
  • Species: Triticum aestivum

Functional Descriptions:

  • The wheat Mla homologue TmMla1 exhibits an evolutionarily conserved function against powdery mildew in both wheat and barley.
  • TmMla1 was found to be a functional resistance gene against Blumeria graminis f. sp. tritici in wheat, hereby providing an example of R gene orthologs controlling the same disease in two different species.
  • TmMla1 not only confers resistance in wheat but possibly also in barley against an as yet unknown barley powdery mildew race.
  • This suggests a high stability of Mla resistance in the natural environment before domestication.

Literature:

Gene Resources:

Orthologs:

Sequences:

cDNA Sequence
  • >JF261156
    ATGGATATTGTCACGGGTGCCATTGCCAAGCTGATCCCCAAGCTGGGAGAACTGCTTGTGGGGGAGTACAAGCTACACAAGGGCATCAAGAAAAATATCGAGGACCTCCTGAAAGAGCTCAACACCATGAACGCTGCGCTCATCAAGATTGGTGAGGTGCCGCCGGACCAGCTCGACAGCCAAGACAAGCTTTGGGCCGATGAGGTCAGAGAGCTCTCCTACGTCATTGAGGATGTGGTGGACAAGTTCCTTGTACGGGTCCATGGCATTGAGCCCGACGACAACACCAACGGATTCAAGGGGCTCATCAAGAGGACCACCAAGTTGTTGAAGAAAGTCGTGGATAAGCATGGGATAGCTCACGCGATCAAGGACATCAAGAAGGAACTCCAGGAGGTGGCTGCTAGGCGTGACAGGAACAAGTTCGATGGTATTGCTTCTGTTCCTACTGAAGCAATCGATCCTCGTCTCCGTGCTCTGTACATAGAAGCGGCAGAGCTAGTTGGCATCTATGGGAAGAGGGATAAGGAGCTCATGAGTTTGCTCTCCTTGGAGGGCGATGATGCCTCTACCAAGAAACTGAAGAAGGTCTCCATTGTTGGATTTGGAGGGTTGGGCAAGACCACTCTTGCCAGAGCAGTATACGAGAAGATTAAAGGTGATTTTGGTTGTCACGCATTTGTTCCTGTCGGGCAAAACCCTGATATCAAGAAGGTGTTCAGGGATATCCTCGTTGATCTCCGAAAATCAAACTCAGATCCTGGCAACTCTAACTCAGATCTTGTGATACTGGATGCAACGCAGCTTATCGACAAGCTTCGTGAATTCCTTGAGAACAAGAGGTATGCATCACTTACAGCAAAATTGTGCACTATTATGACATGATTATTTCCTATGCTAGTTGTACAAGTAACACTAAGTGTATAAACATATTGTAGCGGGAGGGTTCAGAATAATTTTCCCATTGAGGCCACCTTTACTGGCATATGCAGTTCACACTAAACTGTAAACCTTCTAGGTGATAAATTTCAAGCATGTAGAAGTATATACTATGTTACTATGGCTGAAACTTATAGGCATTAGTCCAAGAAATCCATCTAAACATTTTGCATTACACCGAAGTGAGTGTAATGACAACTGTAACAAGTAAGGAAAGACGAAGATAAATGTTACAAAATTTTAAATCAAACTTATTACCATCTCTTTCTTAACCCACCCAGTTTTAAAACGCATATTTTAAAGGGGAGATGGAAATGAGTGCCAAAGGCTACCCAATAAACTTCCTAAAATATTGTATATTGGATCCAAACAAGAAGTTAAATTCTCCCTTCACTAACTCATTATATTCACCATGTATATTCACCAAAATATAGGTGAAAAGATAATGCCATACTATTTGAGTGAGTCTCCAAGAGGTTCATTAGCTGCCATATATTAAATTGGTGAGCCAGTCAATACTAGGATCTTTTCGATATATCTACCTGACCATTTTAACTTCTGTAGTTAATTGTATTCTACATATGGTCACTGATTCAGCAATTTGCTACTTGTGTTGAATCTTAAATATTTATTCATTTTGTTCGTCATTTGATTGGAGGATCATAATGCATGCTTCGTGAGGTAAGGTTATCGAGTTTAAGATGCATGCCTGTTACGAGTTTGTTTCTGAATATTCGCCCTTATAGATGGTTAATTCCACCCATATATTCGTATGCCCTCAGTTTTTTGATATGTGTAGACCTTACACTGATACTCTGAACTAATGTAGGTACCGCGTCATAATTGATGATATATGGGATGAAAAATTGTGGAGATACATCAACCTTGCTTTCTCTATCAGTAACAATCTAAGCAGTCGGCTAATCACCACAACCCGCATTGTCAGTGTCTCCAATTCATGTTGCTCGTCGACTAATGATTCGATTTATCAAATGAAACCTCTTTGTACTGATGATTCCAGAAGGCTCTTCCATAAGAGAATATTTCCCGACAAGAGTGGATGTCCAAATGAATTTGAACAAGTGTCTAAAGATATATTGAAAAAATGTGGTGGGGTACCACTAGCCATCATTACTATTGCTAGTGCTTTGGCTAGTGGCCAGCACGTGAAGCCAAAGCGTGAGTGGGATATTCTGCTCCGGTCCCTTAGCTCTGGACTAATAGAAGATAACAGTTTAGAGGAGATGCGGAGAATACTCTCGTTCAGCTATTATAATCTACCCCCTCATCTGAAAACTTGTCTATTGTACCTATGTATATATCCAGAAGATAGCAAGATTTATAGAGATAGACTGATATGGAAGTGGGTGGCCGAAGGATTTGTCCACCATGGAGATCAAGGGACCAGCCTGTTTTTGGTCGGAATGAACTACTTCAACCAGCTCATTAATAGAAGTATGATCCAGCCAATATATGATGAACTAGGCCAGGTACATGCTTGCCGTGTACATGATATGGTTCTGGACCTTATCTGCAACTTGTCACATGAAGCAAAGTTTGGTAAGTTATTGGATGGCACTAGGAATAGCATATCTTCACAAAGTAATGTCCGCCGTCTGTCCCTTCAGAATAAAGTGGAAGATCATCAAGCCAAGCCTCTCACAAATATCATGAGTATGTCACGAGTGAGGTCAATTACTATGTTTCCACCTGCTGTTAGTATCATGCCAAGTCTGTCAATGTTTGAAGTTCTGCGTGTACTTGATCTGTCGGATTGTAATCTGGGAAAAAGTAGCAGCGTGCAGCTTAACCTCAAGGGTGTTGGACATTTAATCCACCTAAGGTACCTTGGTCTAGCAGGTACTGGAATCAGGGAACTCCCGACTGAGATAGGAAACCTGCAATTTTTGGAGGTGTTGGATCTTGCAAGGAATCGTACGCTAGATGAATTGCCTTCCACTCTTTTTAAATTGAGAAGATTAATCTACCTAAATGTTTATCTCAGTGAGGTGGTTCCAACTCCTGGTGTGTTGCAGAATCTTACATCCATTGAAGTGTTGAGGGGAGTCTTGGTCTCTCTAAACATTATTGCACAAGATCTTGGCAAACTGGCAAGGCTGAGGGAGCTTCAGATTTACTTCAAGGATGATAGTTTGGATTTGTATGAAGGTTTCGTGAAGTCTCTGTGCAACCTACATCACATCGAAATTCTAATTATTGGTAACAATTTCGAAGAAACATCTTTTGAACTGATGGATCTCTTGGGAGAACGCTGGGTGCCTCCTGTACATCTCCGCGAATTTGTGTCGCACATGCCCAGCCAACTCTCTGCACTGCGAGGGTGGATAAAGAGAGACCCCTCGCATCTCTCGAACCTCTCCGAGTTAATCCTCACGTCAGTGAAGGAAGTGCAGCAGGAGGACGTGGAAATCATTGGGGGGTTGCTGTCCCTTCGCTGTCTCTGGATAACGAGCACCCACCAAACACAACGGCTGCTAGTCATCCGTGCAGATGGGTTCCGTTGTATGGTTGACTTTTACTTGAATTGTGGATCAGCAGCGCAAATTAAGTTTGAACCAGGAGCTTTACCGAGGGCGGAAGAAGTTCGGTTCAGTCTGGGCGTGCGGGTGGCGAAAGAGGATGGAAACTGTGGTTTCGACTTGGGCCTGCAGGGGAACCTGCTCTCCCTTCGGCGGCATGTCTGGGTTTATATGTATTGTGGTGGAGCGAGGGTTGGGGAGACCAAGGAAGCGGAGGCTGCGGTGAGGCACGCACTCGAAGCCCATCCCAACCATCCCCTGTTTTATATTCAGATGAAGCCACGTATAGCACAAGGTACTCACGCTGCACCTAATTAATCACTTGTGCACATACGTATTTGTTTTTTTCTAAATGATGGACTGACCTTATTACTCTCTGCATTGATTTTGATCTCTGAATCTACCAAGGTGCTCATGATGACGATTTGTGTGAGGACGAGGAGAACTGA
CDS Sequence
  • >JF261156
    ATGGATATTGTCACGGGTGCCATTGCCAAGCTGATCCCCAAGCTGGGAGAACTGCTTGTGGGGGAGTACAAGCTACACAAGGGCATCAAGAAAAATATCGAGGACCTCCTGAAAGAGCTCAACACCATGAACGCTGCGCTCATCAAGATTGGTGAGGTGCCGCCGGACCAGCTCGACAGCCAAGACAAGCTTTGGGCCGATGAGGTCAGAGAGCTCTCCTACGTCATTGAGGATGTGGTGGACAAGTTCCTTGTACGGGTCCATGGCATTGAGCCCGACGACAACACCAACGGATTCAAGGGGCTCATCAAGAGGACCACCAAGTTGTTGAAGAAAGTCGTGGATAAGCATGGGATAGCTCACGCGATCAAGGACATCAAGAAGGAACTCCAGGAGGTGGCTGCTAGGCGTGACAGGAACAAGTTCGATGGTATTGCTTCTGTTCCTACTGAAGCAATCGATCCTCGTCTCCGTGCTCTGTACATAGAAGCGGCAGAGCTAGTTGGCATCTATGGGAAGAGGGATAAGGAGCTCATGAGTTTGCTCTCCTTGGAGGGCGATGATGCCTCTACCAAGAAACTGAAGAAGGTCTCCATTGTTGGATTTGGAGGGTTGGGCAAGACCACTCTTGCCAGAGCAGTATACGAGAAGATTAAAGGTGATTTTGGTTGTCACGCATTTGTTCCTGTCGGGCAAAACCCTGATATCAAGAAGGTGTTCAGGGATATCCTCGTTGATCTCCGAAAATCAAACTCAGATCCTGGCAACTCTAACTCAGATCTTGTGATACTGGATGCAACGCAGCTTATCGACAAGCTTCGTGAATTCCTTGAGAACAAGAGGTACCGCGTCATAATTGATGATATATGGGATGAAAAATTGTGGAGATACATCAACCTTGCTTTCTCTATCAGTAACAATCTAAGCAGTCGGCTAATCACCACAACCCGCATTGTCAGTGTCTCCAATTCATGTTGCTCGTCGACTAATGATTCGATTTATCAAATGAAACCTCTTTGTACTGATGATTCCAGAAGGCTCTTCCATAAGAGAATATTTCCCGACAAGAGTGGATGTCCAAATGAATTTGAACAAGTGTCTAAAGATATATTGAAAAAATGTGGTGGGGTACCACTAGCCATCATTACTATTGCTAGTGCTTTGGCTAGTGGCCAGCACGTGAAGCCAAAGCGTGAGTGGGATATTCTGCTCCGGTCCCTTAGCTCTGGACTAATAGAAGATAACAGTTTAGAGGAGATGCGGAGAATACTCTCGTTCAGCTATTATAATCTACCCCCTCATCTGAAAACTTGTCTATTGTACCTATGTATATATCCAGAAGATAGCAAGATTTATAGAGATAGACTGATATGGAAGTGGGTGGCCGAAGGATTTGTCCACCATGGAGATCAAGGGACCAGCCTGTTTTTGGTCGGAATGAACTACTTCAACCAGCTCATTAATAGAAGTATGATCCAGCCAATATATGATGAACTAGGCCAGGTACATGCTTGCCGTGTACATGATATGGTTCTGGACCTTATCTGCAACTTGTCACATGAAGCAAAGTTTGGTAAGTTATTGGATGGCACTAGGAATAGCATATCTTCACAAAGTAATGTCCGCCGTCTGTCCCTTCAGAATAAAGTGGAAGATCATCAAGCCAAGCCTCTCACAAATATCATGAGTATGTCACGAGTGAGGTCAATTACTATGTTTCCACCTGCTGTTAGTATCATGCCAAGTCTGTCAATGTTTGAAGTTCTGCGTGTACTTGATCTGTCGGATTGTAATCTGGGAAAAAGTAGCAGCGTGCAGCTTAACCTCAAGGGTGTTGGACATTTAATCCACCTAAGGTACCTTGGTCTAGCAGGTACTGGAATCAGGGAACTCCCGACTGAGATAGGAAACCTGCAATTTTTGGAGGTGTTGGATCTTGCAAGGAATCGTACGCTAGATGAATTGCCTTCCACTCTTTTTAAATTGAGAAGATTAATCTACCTAAATGTTTATCTCAGTGAGGTGGTTCCAACTCCTGGTGTGTTGCAGAATCTTACATCCATTGAAGTGTTGAGGGGAGTCTTGGTCTCTCTAAACATTATTGCACAAGATCTTGGCAAACTGGCAAGGCTGAGGGAGCTTCAGATTTACTTCAAGGATGATAGTTTGGATTTGTATGAAGGTTTCGTGAAGTCTCTGTGCAACCTACATCACATCGAAATTCTAATTATTGGTAACAATTTCGAAGAAACATCTTTTGAACTGATGGATCTCTTGGGAGAACGCTGGGTGCCTCCTGTACATCTCCGCGAATTTGTGTCGCACATGCCCAGCCAACTCTCTGCACTGCGAGGGTGGATAAAGAGAGACCCCTCGCATCTCTCGAACCTCTCCGAGTTAATCCTCACGTCAGTGAAGGAAGTGCAGCAGGAGGACGTGGAAATCATTGGGGGGTTGCTGTCCCTTCGCTGTCTCTGGATAACGAGCACCCACCAAACACAACGGCTGCTAGTCATCCGTGCAGATGGGTTCCGTTGTATGGTTGACTTTTACTTGAATTGTGGATCAGCAGCGCAAATTAAGTTTGAACCAGGAGCTTTACCGAGGGCGGAAGAAGTTCGGTTCAGTCTGGGCGTGCGGGTGGCGAAAGAGGATGGAAACTGTGGTTTCGACTTGGGCCTGCAGGGGAACCTGCTCTCCCTTCGGCGGCATGTCTGGGTTTATATGTATTGTGGTGGAGCGAGGGTTGGGGAGACCAAGGAAGCGGAGGCTGCGGTGAGGCACGCACTCGAAGCCCATCCCAACCATCCCCTGTTTTATATTCAGATGAAGCCACGTATAGCACAAGGTGCTCATGATGACGATTTGTGTGAGGACGAGGAGAACTGA
Protein Sequence
  • >JF261156
    MDIVTGAIAKLIPKLGELLVGEYKLHKGIKKNIEDLLKELNTMNAALIKIGEVPPDQLDSQDKLWADEVRELSYVIEDVVDKFLVRVHGIEPDDNTNGFKGLIKRTTKLLKKVVDKHGIAHAIKDIKKELQEVAARRDRNKFDGIASVPTEAIDPRLRALYIEAAELVGIYGKRDKELMSLLSLEGDDASTKKLKKVSIVGFGGLGKTTLARAVYEKIKGDFGCHAFVPVGQNPDIKKVFRDILVDLRKSNSDPGNSNSDLVILDATQLIDKLREFLENKRYRVIIDDIWDEKLWRYINLAFSISNNLSSRLITTTRIVSVSNSCCSSTNDSIYQMKPLCTDDSRRLFHKRIFPDKSGCPNEFEQVSKDILKKCGGVPLAIITIASALASGQHVKPKREWDILLRSLSSGLIEDNSLEEMRRILSFSYYNLPPHLKTCLLYLCIYPEDSKIYRDRLIWKWVAEGFVHHGDQGTSLFLVGMNYFNQLINRSMIQPIYDELGQVHACRVHDMVLDLICNLSHEAKFGKLLDGTRNSISSQSNVRRLSLQNKVEDHQAKPLTNIMSMSRVRSITMFPPAVSIMPSLSMFEVLRVLDLSDCNLGKSSSVQLNLKGVGHLIHLRYLGLAGTGIRELPTEIGNLQFLEVLDLARNRTLDELPSTLFKLRRLIYLNVYLSEVVPTPGVLQNLTSIEVLRGVLVSLNIIAQDLGKLARLRELQIYFKDDSLDLYEGFVKSLCNLHHIEILIIGNNFEETSFELMDLLGERWVPPVHLREFVSHMPSQLSALRGWIKRDPSHLSNLSELILTSVKEVQQEDVEIIGGLLSLRCLWITSTHQTQRLLVIRADGFRCMVDFYLNCGSAAQIKFEPGALPRAEEVRFSLGVRVAKEDGNCGFDLGLQGNLLSLRRHVWVYMYCGGARVGETKEAEAAVRHALEAHPNHPLFYIQMKPRIAQGAHDDDLCEDEEN