Gene Details:
- Gene ID:
- Gene Symbol: TmMla1
- Gene Name: Mla homologue 1
- Genome: Chinese_Spring1.0
- Species: Triticum aestivum
Functional Descriptions:
- The wheat Mla homologue TmMla1 exhibits an evolutionarily conserved function against powdery mildew in both wheat and barley.
- TmMla1 was found to be a functional resistance gene against Blumeria graminis f. sp. tritici in wheat, hereby providing an example of R gene orthologs controlling the same disease in two different species.
- TmMla1 not only confers resistance in wheat but possibly also in barley against an as yet unknown barley powdery mildew race.
- This suggests a high stability of Mla resistance in the natural environment before domestication.
Function-related keywords:
- resistance , domestication , disease , disease-resistance , powdery-mildew , mildew-resistance , mildew , powdery-mildew-resistance
Literature:
- The wheat Mla homologue TmMla1 exhibits an evolutionarily conserved function against powdery mildew in both wheat and barley. DOI: 10.1111/j.1365-313X.2010.04445.x ; PMID: 21208308
Related News:
Gene Resources:
Orthologs:
Sequences:
cDNA Sequence
- >JF261156
ATGGATATTGTCACGGGTGCCATTGCCAAGCTGATCCCCAAGCTGGGAGAACTGCTTGTGGGGGAGTACAAGCTACACAAGGGCATCAAGAAAAATATCGAGGACCTCCTGAAAGAGCTCAACACCATGAACGCTGCGCTCATCAAGATTGGTGAGGTGCCGCCGGACCAGCTCGACAGCCAAGACAAGCTTTGGGCCGATGAGGTCAGAGAGCTCTCCTACGTCATTGAGGATGTGGTGGACAAGTTCCTTGTACGGGTCCATGGCATTGAGCCCGACGACAACACCAACGGATTCAAGGGGCTCATCAAGAGGACCACCAAGTTGTTGAAGAAAGTCGTGGATAAGCATGGGATAGCTCACGCGATCAAGGACATCAAGAAGGAACTCCAGGAGGTGGCTGCTAGGCGTGACAGGAACAAGTTCGATGGTATTGCTTCTGTTCCTACTGAAGCAATCGATCCTCGTCTCCGTGCTCTGTACATAGAAGCGGCAGAGCTAGTTGGCATCTATGGGAAGAGGGATAAGGAGCTCATGAGTTTGCTCTCCTTGGAGGGCGATGATGCCTCTACCAAGAAACTGAAGAAGGTCTCCATTGTTGGATTTGGAGGGTTGGGCAAGACCACTCTTGCCAGAGCAGTATACGAGAAGATTAAAGGTGATTTTGGTTGTCACGCATTTGTTCCTGTCGGGCAAAACCCTGATATCAAGAAGGTGTTCAGGGATATCCTCGTTGATCTCCGAAAATCAAACTCAGATCCTGGCAACTCTAACTCAGATCTTGTGATACTGGATGCAACGCAGCTTATCGACAAGCTTCGTGAATTCCTTGAGAACAAGAGGTATGCATCACTTACAGCAAAATTGTGCACTATTATGACATGATTATTTCCTATGCTAGTTGTACAAGTAACACTAAGTGTATAAACATATTGTAGCGGGAGGGTTCAGAATAATTTTCCCATTGAGGCCACCTTTACTGGCATATGCAGTTCACACTAAACTGTAAACCTTCTAGGTGATAAATTTCAAGCATGTAGAAGTATATACTATGTTACTATGGCTGAAACTTATAGGCATTAGTCCAAGAAATCCATCTAAACATTTTGCATTACACCGAAGTGAGTGTAATGACAACTGTAACAAGTAAGGAAAGACGAAGATAAATGTTACAAAATTTTAAATCAAACTTATTACCATCTCTTTCTTAACCCACCCAGTTTTAAAACGCATATTTTAAAGGGGAGATGGAAATGAGTGCCAAAGGCTACCCAATAAACTTCCTAAAATATTGTATATTGGATCCAAACAAGAAGTTAAATTCTCCCTTCACTAACTCATTATATTCACCATGTATATTCACCAAAATATAGGTGAAAAGATAATGCCATACTATTTGAGTGAGTCTCCAAGAGGTTCATTAGCTGCCATATATTAAATTGGTGAGCCAGTCAATACTAGGATCTTTTCGATATATCTACCTGACCATTTTAACTTCTGTAGTTAATTGTATTCTACATATGGTCACTGATTCAGCAATTTGCTACTTGTGTTGAATCTTAAATATTTATTCATTTTGTTCGTCATTTGATTGGAGGATCATAATGCATGCTTCGTGAGGTAAGGTTATCGAGTTTAAGATGCATGCCTGTTACGAGTTTGTTTCTGAATATTCGCCCTTATAGATGGTTAATTCCACCCATATATTCGTATGCCCTCAGTTTTTTGATATGTGTAGACCTTACACTGATACTCTGAACTAATGTAGGTACCGCGTCATAATTGATGATATATGGGATGAAAAATTGTGGAGATACATCAACCTTGCTTTCTCTATCAGTAACAATCTAAGCAGTCGGCTAATCACCACAACCCGCATTGTCAGTGTCTCCAATTCATGTTGCTCGTCGACTAATGATTCGATTTATCAAATGAAACCTCTTTGTACTGATGATTCCAGAAGGCTCTTCCATAAGAGAATATTTCCCGACAAGAGTGGATGTCCAAATGAATTTGAACAAGTGTCTAAAGATATATTGAAAAAATGTGGTGGGGTACCACTAGCCATCATTACTATTGCTAGTGCTTTGGCTAGTGGCCAGCACGTGAAGCCAAAGCGTGAGTGGGATATTCTGCTCCGGTCCCTTAGCTCTGGACTAATAGAAGATAACAGTTTAGAGGAGATGCGGAGAATACTCTCGTTCAGCTATTATAATCTACCCCCTCATCTGAAAACTTGTCTATTGTACCTATGTATATATCCAGAAGATAGCAAGATTTATAGAGATAGACTGATATGGAAGTGGGTGGCCGAAGGATTTGTCCACCATGGAGATCAAGGGACCAGCCTGTTTTTGGTCGGAATGAACTACTTCAACCAGCTCATTAATAGAAGTATGATCCAGCCAATATATGATGAACTAGGCCAGGTACATGCTTGCCGTGTACATGATATGGTTCTGGACCTTATCTGCAACTTGTCACATGAAGCAAAGTTTGGTAAGTTATTGGATGGCACTAGGAATAGCATATCTTCACAAAGTAATGTCCGCCGTCTGTCCCTTCAGAATAAAGTGGAAGATCATCAAGCCAAGCCTCTCACAAATATCATGAGTATGTCACGAGTGAGGTCAATTACTATGTTTCCACCTGCTGTTAGTATCATGCCAAGTCTGTCAATGTTTGAAGTTCTGCGTGTACTTGATCTGTCGGATTGTAATCTGGGAAAAAGTAGCAGCGTGCAGCTTAACCTCAAGGGTGTTGGACATTTAATCCACCTAAGGTACCTTGGTCTAGCAGGTACTGGAATCAGGGAACTCCCGACTGAGATAGGAAACCTGCAATTTTTGGAGGTGTTGGATCTTGCAAGGAATCGTACGCTAGATGAATTGCCTTCCACTCTTTTTAAATTGAGAAGATTAATCTACCTAAATGTTTATCTCAGTGAGGTGGTTCCAACTCCTGGTGTGTTGCAGAATCTTACATCCATTGAAGTGTTGAGGGGAGTCTTGGTCTCTCTAAACATTATTGCACAAGATCTTGGCAAACTGGCAAGGCTGAGGGAGCTTCAGATTTACTTCAAGGATGATAGTTTGGATTTGTATGAAGGTTTCGTGAAGTCTCTGTGCAACCTACATCACATCGAAATTCTAATTATTGGTAACAATTTCGAAGAAACATCTTTTGAACTGATGGATCTCTTGGGAGAACGCTGGGTGCCTCCTGTACATCTCCGCGAATTTGTGTCGCACATGCCCAGCCAACTCTCTGCACTGCGAGGGTGGATAAAGAGAGACCCCTCGCATCTCTCGAACCTCTCCGAGTTAATCCTCACGTCAGTGAAGGAAGTGCAGCAGGAGGACGTGGAAATCATTGGGGGGTTGCTGTCCCTTCGCTGTCTCTGGATAACGAGCACCCACCAAACACAACGGCTGCTAGTCATCCGTGCAGATGGGTTCCGTTGTATGGTTGACTTTTACTTGAATTGTGGATCAGCAGCGCAAATTAAGTTTGAACCAGGAGCTTTACCGAGGGCGGAAGAAGTTCGGTTCAGTCTGGGCGTGCGGGTGGCGAAAGAGGATGGAAACTGTGGTTTCGACTTGGGCCTGCAGGGGAACCTGCTCTCCCTTCGGCGGCATGTCTGGGTTTATATGTATTGTGGTGGAGCGAGGGTTGGGGAGACCAAGGAAGCGGAGGCTGCGGTGAGGCACGCACTCGAAGCCCATCCCAACCATCCCCTGTTTTATATTCAGATGAAGCCACGTATAGCACAAGGTACTCACGCTGCACCTAATTAATCACTTGTGCACATACGTATTTGTTTTTTTCTAAATGATGGACTGACCTTATTACTCTCTGCATTGATTTTGATCTCTGAATCTACCAAGGTGCTCATGATGACGATTTGTGTGAGGACGAGGAGAACTGA
CDS Sequence
- >JF261156
ATGGATATTGTCACGGGTGCCATTGCCAAGCTGATCCCCAAGCTGGGAGAACTGCTTGTGGGGGAGTACAAGCTACACAAGGGCATCAAGAAAAATATCGAGGACCTCCTGAAAGAGCTCAACACCATGAACGCTGCGCTCATCAAGATTGGTGAGGTGCCGCCGGACCAGCTCGACAGCCAAGACAAGCTTTGGGCCGATGAGGTCAGAGAGCTCTCCTACGTCATTGAGGATGTGGTGGACAAGTTCCTTGTACGGGTCCATGGCATTGAGCCCGACGACAACACCAACGGATTCAAGGGGCTCATCAAGAGGACCACCAAGTTGTTGAAGAAAGTCGTGGATAAGCATGGGATAGCTCACGCGATCAAGGACATCAAGAAGGAACTCCAGGAGGTGGCTGCTAGGCGTGACAGGAACAAGTTCGATGGTATTGCTTCTGTTCCTACTGAAGCAATCGATCCTCGTCTCCGTGCTCTGTACATAGAAGCGGCAGAGCTAGTTGGCATCTATGGGAAGAGGGATAAGGAGCTCATGAGTTTGCTCTCCTTGGAGGGCGATGATGCCTCTACCAAGAAACTGAAGAAGGTCTCCATTGTTGGATTTGGAGGGTTGGGCAAGACCACTCTTGCCAGAGCAGTATACGAGAAGATTAAAGGTGATTTTGGTTGTCACGCATTTGTTCCTGTCGGGCAAAACCCTGATATCAAGAAGGTGTTCAGGGATATCCTCGTTGATCTCCGAAAATCAAACTCAGATCCTGGCAACTCTAACTCAGATCTTGTGATACTGGATGCAACGCAGCTTATCGACAAGCTTCGTGAATTCCTTGAGAACAAGAGGTACCGCGTCATAATTGATGATATATGGGATGAAAAATTGTGGAGATACATCAACCTTGCTTTCTCTATCAGTAACAATCTAAGCAGTCGGCTAATCACCACAACCCGCATTGTCAGTGTCTCCAATTCATGTTGCTCGTCGACTAATGATTCGATTTATCAAATGAAACCTCTTTGTACTGATGATTCCAGAAGGCTCTTCCATAAGAGAATATTTCCCGACAAGAGTGGATGTCCAAATGAATTTGAACAAGTGTCTAAAGATATATTGAAAAAATGTGGTGGGGTACCACTAGCCATCATTACTATTGCTAGTGCTTTGGCTAGTGGCCAGCACGTGAAGCCAAAGCGTGAGTGGGATATTCTGCTCCGGTCCCTTAGCTCTGGACTAATAGAAGATAACAGTTTAGAGGAGATGCGGAGAATACTCTCGTTCAGCTATTATAATCTACCCCCTCATCTGAAAACTTGTCTATTGTACCTATGTATATATCCAGAAGATAGCAAGATTTATAGAGATAGACTGATATGGAAGTGGGTGGCCGAAGGATTTGTCCACCATGGAGATCAAGGGACCAGCCTGTTTTTGGTCGGAATGAACTACTTCAACCAGCTCATTAATAGAAGTATGATCCAGCCAATATATGATGAACTAGGCCAGGTACATGCTTGCCGTGTACATGATATGGTTCTGGACCTTATCTGCAACTTGTCACATGAAGCAAAGTTTGGTAAGTTATTGGATGGCACTAGGAATAGCATATCTTCACAAAGTAATGTCCGCCGTCTGTCCCTTCAGAATAAAGTGGAAGATCATCAAGCCAAGCCTCTCACAAATATCATGAGTATGTCACGAGTGAGGTCAATTACTATGTTTCCACCTGCTGTTAGTATCATGCCAAGTCTGTCAATGTTTGAAGTTCTGCGTGTACTTGATCTGTCGGATTGTAATCTGGGAAAAAGTAGCAGCGTGCAGCTTAACCTCAAGGGTGTTGGACATTTAATCCACCTAAGGTACCTTGGTCTAGCAGGTACTGGAATCAGGGAACTCCCGACTGAGATAGGAAACCTGCAATTTTTGGAGGTGTTGGATCTTGCAAGGAATCGTACGCTAGATGAATTGCCTTCCACTCTTTTTAAATTGAGAAGATTAATCTACCTAAATGTTTATCTCAGTGAGGTGGTTCCAACTCCTGGTGTGTTGCAGAATCTTACATCCATTGAAGTGTTGAGGGGAGTCTTGGTCTCTCTAAACATTATTGCACAAGATCTTGGCAAACTGGCAAGGCTGAGGGAGCTTCAGATTTACTTCAAGGATGATAGTTTGGATTTGTATGAAGGTTTCGTGAAGTCTCTGTGCAACCTACATCACATCGAAATTCTAATTATTGGTAACAATTTCGAAGAAACATCTTTTGAACTGATGGATCTCTTGGGAGAACGCTGGGTGCCTCCTGTACATCTCCGCGAATTTGTGTCGCACATGCCCAGCCAACTCTCTGCACTGCGAGGGTGGATAAAGAGAGACCCCTCGCATCTCTCGAACCTCTCCGAGTTAATCCTCACGTCAGTGAAGGAAGTGCAGCAGGAGGACGTGGAAATCATTGGGGGGTTGCTGTCCCTTCGCTGTCTCTGGATAACGAGCACCCACCAAACACAACGGCTGCTAGTCATCCGTGCAGATGGGTTCCGTTGTATGGTTGACTTTTACTTGAATTGTGGATCAGCAGCGCAAATTAAGTTTGAACCAGGAGCTTTACCGAGGGCGGAAGAAGTTCGGTTCAGTCTGGGCGTGCGGGTGGCGAAAGAGGATGGAAACTGTGGTTTCGACTTGGGCCTGCAGGGGAACCTGCTCTCCCTTCGGCGGCATGTCTGGGTTTATATGTATTGTGGTGGAGCGAGGGTTGGGGAGACCAAGGAAGCGGAGGCTGCGGTGAGGCACGCACTCGAAGCCCATCCCAACCATCCCCTGTTTTATATTCAGATGAAGCCACGTATAGCACAAGGTGCTCATGATGACGATTTGTGTGAGGACGAGGAGAACTGA
Protein Sequence
- >JF261156
MDIVTGAIAKLIPKLGELLVGEYKLHKGIKKNIEDLLKELNTMNAALIKIGEVPPDQLDSQDKLWADEVRELSYVIEDVVDKFLVRVHGIEPDDNTNGFKGLIKRTTKLLKKVVDKHGIAHAIKDIKKELQEVAARRDRNKFDGIASVPTEAIDPRLRALYIEAAELVGIYGKRDKELMSLLSLEGDDASTKKLKKVSIVGFGGLGKTTLARAVYEKIKGDFGCHAFVPVGQNPDIKKVFRDILVDLRKSNSDPGNSNSDLVILDATQLIDKLREFLENKRYRVIIDDIWDEKLWRYINLAFSISNNLSSRLITTTRIVSVSNSCCSSTNDSIYQMKPLCTDDSRRLFHKRIFPDKSGCPNEFEQVSKDILKKCGGVPLAIITIASALASGQHVKPKREWDILLRSLSSGLIEDNSLEEMRRILSFSYYNLPPHLKTCLLYLCIYPEDSKIYRDRLIWKWVAEGFVHHGDQGTSLFLVGMNYFNQLINRSMIQPIYDELGQVHACRVHDMVLDLICNLSHEAKFGKLLDGTRNSISSQSNVRRLSLQNKVEDHQAKPLTNIMSMSRVRSITMFPPAVSIMPSLSMFEVLRVLDLSDCNLGKSSSVQLNLKGVGHLIHLRYLGLAGTGIRELPTEIGNLQFLEVLDLARNRTLDELPSTLFKLRRLIYLNVYLSEVVPTPGVLQNLTSIEVLRGVLVSLNIIAQDLGKLARLRELQIYFKDDSLDLYEGFVKSLCNLHHIEILIIGNNFEETSFELMDLLGERWVPPVHLREFVSHMPSQLSALRGWIKRDPSHLSNLSELILTSVKEVQQEDVEIIGGLLSLRCLWITSTHQTQRLLVIRADGFRCMVDFYLNCGSAAQIKFEPGALPRAEEVRFSLGVRVAKEDGNCGFDLGLQGNLLSLRRHVWVYMYCGGARVGETKEAEAAVRHALEAHPNHPLFYIQMKPRIAQGAHDDDLCEDEEN