Gene Details:

• Gene ID: TraesCS6D02G129900
• Gene Symbol: TaPsIPK1-6D
• Gene Name: Puccinia striiformis-Induced Protein Kinase 1
• Genome: Chinese_Spring1.0
• Species: Triticum aestivum

Functional Descriptions:

• Wheat kinase TaPsIPK1 is a susceptibility gene employed by Pst effector PsSpg1.
• Editing TaPsIPK1 confers robust rust resistance without growth and yield penalty.
• The transient and stable silencing of the three homoeologs TaPsIPK1-6A, TaPsIPK1-6B, and TaPsIPK1-6D significantly decreased the susceptibility of wheat cultivars to Pst, indicating its negative contribution to wheat stripe rust resistance.
• TaPsIPK1 appears to function as a negative regulator of immunity to stripe rust in wheat.
• CRISPR-Cas9 editing of TaPsIPK1 confers broad-spectrum stripe rust resistance without loss of key agronomic traits.
• TaPsIPK1 interacts with TaCBF1d, which positively regulates wheat resistance.
• TaPsIPK1 is an ideal target for engineering broad-spectrum resistance to one of the most damaging diseases in wheat.

Function-related keywords:

• growth ,  kinase ,  resistance ,  yield ,  immunity ,  rust-resistance ,  rust

Literature:

• Inactivation of a wheat protein kinase gene confers broad-spectrum resistance to rust fungi.   DOI:  10.1016/j.cell.2022.06.027 ;  PMID:  35839760

Related News:

• Cell | 西北农林科技大学植物免疫团队在小麦感条锈病机制取得重大突破

Gene Resources:

• NCBI ID: 123143984
• UniProt accessions: A0A3B6QF07

Sequences: