Information report for TaPsIPK1-6B
Gene Details
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Functional Descriptions
- Wheat kinase TaPsIPK1 is a susceptibility gene employed by Pst effector PsSpg1.
- Editing TaPsIPK1 confers robust rust resistance without growth and yield penalty.
- The transient and stable silencing of the three homoeologs TaPsIPK1-6A, TaPsIPK1-6B, and TaPsIPK1-6D significantly decreased the susceptibility of wheat cultivars to Pst, indicating its negative contribution to wheat stripe rust resistance.
- TaPsIPK1 appears to function as a negative regulator of immunity to stripe rust in wheat.
- CRISPR-Cas9 editing of TaPsIPK1 confers broad-spectrum stripe rust resistance without loss of key agronomic traits.
- TaPsIPK1 interacts with TaCBF1d, which positively regulates wheat resistance.
- TaPsIPK1 is an ideal target for engineering broad-spectrum resistance to one of the most damaging diseases in wheat.
Functional Keywords
- growth , kinase , resistance , yield , immunity , rust-resistance , rust
Literature and News
Gene Resources
- NCBI ID: 123136479
- UniProt accessions: F6LWC1
- EnsemblPlants: TraesCS6B02G167900.1
- Gramene: TraesCS6B02G167900.1
- GO: GO:0004674 , GO:0005524
- OMA: TQDVTKH
- ExpressionAtlas: TraesCS6B02G167900
- InterPro: IPR000719 , IPR008271 , IPR011009 , IPR017441 , IPR052059
- PANTHER: PTHR47973
- SUPFAM: SSF56112
- PROSITE: PS00107 , PS00108 , PS50011
- Gene3D: 1.10.510.10 , 3.30.200.20
- OrthoDB: F6LWC1
- SMR: F6LWC1
- CDD: cd14066
Sequences
cDNA Sequence
- >TraesCS6B02G167900.1
TCCTTCCCCTCCTCTTCCTCCCTCCCCCACCGCGGAAGCACAAGTCAAATAATCACTCGGGACCGAAACCTCACAGTCCAACGCCGCCATTTCCCACCCGCCTCCTCCTCCTCCTCCTCCTCCCAGCCCCCGCCCGCCGCCGCCGCCTCTGCGCTAAGTCCAAGGGCTGCGCTCGTGCTCGGGAACCCTCGCGGCCGCTGACGACTCGCCGGGTCTGCTTGCTTGAGGAGCGGTGCCTGTCTGCCTGCGCGCGCTGCGAGGGTGGCGGTAACTTCTTCTGCGGTCTCGGATCGCGTCGGATTCGAGTTTCCCGGGCGGCTGTTCCCCGGGGCTGGAAGGTGGATTAGGCTGCGGTTGGTCAGGATATGATGGCAGCTGTTTAAGGTTGGTGAAATGTCTGTGCGGATATCATAAGTGCAAACATATTTATTGAACTGACAACGGCAAGGCAGACATATTTTGAGAATATAAGTAATGGGTTGTTCTCCTTTCTTCTGCTATAAAAGTGGGGCAACACGCCAGCAAATTTCTACGCATACTGAAGACCTCCCTGGTGATATTAATACAATAAGATACACTTATAAGGAGCTAGCAAGGGCAACAGAAAATTTTAACCCATCCAACAAGATTGGTGAGGGGGGTTTTGGATCTGTATATAAGGGGCGGCTAAGGAATGGAAAACTTATTGCTGTCAAGGTGTTATCTGTAGAATCAAGACAAGGACTAAAGGAGTTTCTGAATGAACTGATGTCAATTTCCAACATATCTCATGGCAATCTTGTCAGCCTTTATGGCTATTGTGTGGAAGGAAACCAGAGGATCCTTGTCTACAATTACCTTGAGAATAATAGCCTTGCACAAACACTTCTAGGTTCTGGCCGCAGCAATATCCAGTTCAATTGGAGAAGTAGAGTAAATATTTGCCTTGGTATCGCCCGAGGATTAGCATACCTCCATGATGATGTCAATCCCCACATTGTTCATCGGGATATCAAAGCAAGCAATATACTTCTTGATAAGGATCTCACCCCCAAAATTTCTGATTTCGGTTTAGCAAAGCTTCTACCTCCAAATGCGTCACATATTAGCACACGGGTTGCAGGAACATTAGGTTACTTGGCTCCTGAGTACGCCATTCGAGGACAAGTGACACGGAAGTCAGATGTTTATAGTTTTGGTGTTTTGCTTCTGGAAATAGTCAGTGGGAGATCCAACACCAGTTCAAGATTACCCTATGAAGATCAGATACTTCTGGAAAAGTTCCCAGAGGTTACCAACGGGGTTCTCCTCTTGCAGACATGGATGTATTATGAGCAGGGAGATTTGGCGAAAATCATAGACAGTTCTGCGGGTGATGATTTGGATATTGAACAAGCCTGCAGGTTCCTGAAAGTTGGACTTCTCTGTACACAAGATGTCACAAGACATCGACCCACTATGTCAACTGTCGTCAGCATGCTAACAGGCGAAAAGGATGTTGACTCGGAGAAGATCAGCAAGCCCGCTACAATTAGCGACTTTATGGACCTTAAGATCAGGAGCATGAGGAGAGAAAATAACATTGCTTTCGCTTCATCCTCCACGTTGCTATCCACTATCATGGCACACTCTTCTCCTTTGTTGTCACAAGAGACGACACAAGCCTCCATAACATTCACCGCAATATCAGAGCGTGAGTGACCTGAAGTTGGTTGCAAATACAAAGACCATGTAGAAAAGTAGCATAGCCAGATACCCTTTTTTCCAGAAGTTTTCTCCCTAGTGTATAGATTCACTTCGTTTATGGTGTACACAGCATTGCTGGGACAAAGAAGTTCATGAGTTTTACTTTGTGTGTACAATGCTAGATTGGTGGCGCAATGTCCTTGTATAATTTGTGCATGTACATCCTGTCTGTTGTTTGTTTGGTGGGTAAAAAAGAAAAATACAAGTTTGAGATCCTTGTGAG
CDS Sequence
- >TraesCS6B02G167900.1
ATGGGTTGTTCTCCTTTCTTCTGCTATAAAAGTGGGGCAACACGCCAGCAAATTTCTACGCATACTGAAGACCTCCCTGGTGATATTAATACAATAAGATACACTTATAAGGAGCTAGCAAGGGCAACAGAAAATTTTAACCCATCCAACAAGATTGGTGAGGGGGGTTTTGGATCTGTATATAAGGGGCGGCTAAGGAATGGAAAACTTATTGCTGTCAAGGTGTTATCTGTAGAATCAAGACAAGGACTAAAGGAGTTTCTGAATGAACTGATGTCAATTTCCAACATATCTCATGGCAATCTTGTCAGCCTTTATGGCTATTGTGTGGAAGGAAACCAGAGGATCCTTGTCTACAATTACCTTGAGAATAATAGCCTTGCACAAACACTTCTAGGTTCTGGCCGCAGCAATATCCAGTTCAATTGGAGAAGTAGAGTAAATATTTGCCTTGGTATCGCCCGAGGATTAGCATACCTCCATGATGATGTCAATCCCCACATTGTTCATCGGGATATCAAAGCAAGCAATATACTTCTTGATAAGGATCTCACCCCCAAAATTTCTGATTTCGGTTTAGCAAAGCTTCTACCTCCAAATGCGTCACATATTAGCACACGGGTTGCAGGAACATTAGGTTACTTGGCTCCTGAGTACGCCATTCGAGGACAAGTGACACGGAAGTCAGATGTTTATAGTTTTGGTGTTTTGCTTCTGGAAATAGTCAGTGGGAGATCCAACACCAGTTCAAGATTACCCTATGAAGATCAGATACTTCTGGAAAAGTTCCCAGAGGTTACCAACGGGGTTCTCCTCTTGCAGACATGGATGTATTATGAGCAGGGAGATTTGGCGAAAATCATAGACAGTTCTGCGGGTGATGATTTGGATATTGAACAAGCCTGCAGGTTCCTGAAAGTTGGACTTCTCTGTACACAAGATGTCACAAGACATCGACCCACTATGTCAACTGTCGTCAGCATGCTAACAGGCGAAAAGGATGTTGACTCGGAGAAGATCAGCAAGCCCGCTACAATTAGCGACTTTATGGACCTTAAGATCAGGAGCATGAGGAGAGAAAATAACATTGCTTTCGCTTCATCCTCCACGTTGCTATCCACTATCATGGCACACTCTTCTCCTTTGTTGTCACAAGAGACGACACAAGCCTCCATAACATTCACCGCAATATCAGAGCGTGAGTGA
Protein Sequence
- >TraesCS6B02G167900.1
MGCSPFFCYKSGATRQQISTHTEDLPGDINTIRYTYKELARATENFNPSNKIGEGGFGSVYKGRLRNGKLIAVKVLSVESRQGLKEFLNELMSISNISHGNLVSLYGYCVEGNQRILVYNYLENNSLAQTLLGSGRSNIQFNWRSRVNICLGIARGLAYLHDDVNPHIVHRDIKASNILLDKDLTPKISDFGLAKLLPPNASHISTRVAGTLGYLAPEYAIRGQVTRKSDVYSFGVLLLEIVSGRSNTSSRLPYEDQILLEKFPEVTNGVLLLQTWMYYEQGDLAKIIDSSAGDDLDIEQACRFLKVGLLCTQDVTRHRPTMSTVVSMLTGEKDVDSEKISKPATISDFMDLKIRSMRRENNIAFASSSTLLSTIMAHSSPLLSQETTQASITFTAISERE