Gene Details:

• Gene ID: TraesCS4A02G107900
• Gene Symbol: TaPDIL5-1-4A
• Gene Name: protein disulfide isomerase-like 5-1
• Genome: Chinese_Spring1.0
• Species: Triticum aestivum

Functional Descriptions:

• Simultaneous editing of host factor gene TaPDIL5-1 homoeoalleles confers wheat yellow mosaic virus resistance in hexaploid wheat.
• TaPDIL5-1 homoeoalleles did not affect agronomic performance, the simultaneous knockout of all three copies of this susceptibility factor gene can be used to improve virus resistance in wheat.
• These results demonstrate that triple editing of the three TaPDIL5-1 homoeoalleles was sufficient to achieve reliable resistance against WYMV in hexaploid wheat.
• Demonstrates the functional redundancy of the TaPDIL5-1 homoeologues and their ability to compensate for each other in their compatibility with virus infection.
• Since loss of the TaPDIL5-1 homoeoalleles did not affect agronomic performance, the simultaneous knockout of all three copies of this susceptibility factor gene can be used to improve virus resistance in wheat.

Function-related keywords:

• resistance

Literature:

• Simultaneous editing of host factor gene TaPDIL5-1 homoeoalleles confers wheat yellow mosaic virus resistance in hexaploid wheat.   DOI:  10.1111/nph.18002 ;  PMID:  35092005

Related News:

• 打破多倍体基因功能冗余-中国农科院作科所证实首个小麦隐性抗病毒基因

Gene Resources:

• NCBI ID: 123085553
• UniProt accessions: A0A3B6HTU4

Sequences: