Gene Details:
- Gene ID:
- Gene Symbol: TaMED25-B
- Gene Name: Mediator subunit 25
- Genome: Chinese_Spring1.0
- Species: Triticum aestivum
Functional Descriptions:
- The Wheat Mediator Subunit TaMED25 Interacts with the Transcription Factor TaEIL1 to Negatively Regulate Disease Resistance against Powdery Mildew.
- Report the function and molecular mechanism of the bread wheat Mediator subunit 25 (TaMED25) in regulating the bread wheat immune response signaling pathway.
- Knockdown of TaMED25 by barley stripe mosaic virus-induced gene silencing reduced bread wheat susceptibility to the powdery mildew fungus during the compatible plant-pathogen interaction.
- TaMED25 and TaEIL1 synergistically activate ETHYLENE RESPONSE FACTOR1 (TaERF1) transcription to modulate bread wheat basal disease resistance to B. graminis f. sp. tritici by repressing the expression of pathogenesis-related genes and deterring the accumulation of reactive oxygen species.
Function-related keywords:
- transcription-factor , resistance , disease , disease-resistance , ethylene , pathogen , immune-response , signaling-pathway-gene , reactive-oxygen-species , ethylene-response , pathogen-resistance , powdery-mildew , mildew-resistance , mildew , powdery-mildew-resistance , virus
Literature:
- The Wheat Mediator Subunit TaMED25 Interacts with the Transcription Factor TaEIL1 to Negatively Regulate Disease Resistance against Powdery Mildew. DOI: 10.1104/pp.15.01784 ; PMID: 26813794
Related News:
Gene Resources:
- NCBI ID: KU030835
- UniProt accessions: A0A146BAB1
Orthologs:
Sequences:
cDNA Sequence
- >KU030835
ATGGTGGAGGGGATGGCTTCGGAGAGGCAGCTGGTGGTGGTCGTTGAGGGCACGGCGGCGCTGGGGCCGTACTGGCCCGCCATTGCGGCCGAGTACGTCGAGAAGATCGTTCGGAGTTTTTGTTCTACTGAACTATCAGGGCAGAAGCTTGCAGGGGTACCACCTGAGCTTGCATTAGTTGTCTTCCATACCCACGGACCATACAGTGCCTTTATTGTACAACGCAGCGGTTGGACAAAAGATATGGATGCTTTTCTTTCATGGTTATCAGGAATATCATTTAGTGGTGGAGGCTTCAGTGAAGCTGCTATTTGTGAAGGTCTTGCTGAAGCACTGATGATACTCCAAGGCAGTTCTAGTAGCAGCCAGAATCATCAAAATCGTGAACTTCAAAAGCATTGCCTACTTGTTGCTGCAAGTAATCCTTACCCGCTGCCTACACCTGTCTACCGCCCTTCTGTTCAAAGTAGTGATCACAAAAAGAGCAACGAAGCAACAAAGGAATCATGTCTTGCTGATGCTGAGGCTGTTGCAGTCTCATTTGCTCAGTGCTCTGTGTCATTGTCGGTGGTATCTCCTAAACAGCTACCAACACTGAAGGCAATATACAACGCGGGAAAGAGGAATCCTCAAGCTTCTGATCCATCAGTTGATCATGCCAAAAATCCACATTTTCTTGTTTTGCTCTCTGAGAGTTTCATGGAGGCTCGAACAGCTCTAAGCCATCCTTTACCCGGGAACCTTGTCCCAAACCACACCATTACAAAAATGGATACCACACCTGCAGCTACTGTGCCAGGACCACCTTCGAATGCCAGTCCCTCAGTGAATGGAACGATGATGGGACGGCAACCGACTGCAAATGTTAAAGTGGAGCCAACAACTATACCACCAATGGTTTCTGCACCTGCATTCTCTCATATGACACCTATTTCAAATGTTGCTTCTCAAGGTGTATCAGCAATGCAAACTTCTTCACCATCGATTATTTCACAAGAAACAAATGTTGCAAATGAAATATTGCAAGAGCATAAGCCTTTAGTAAACCCTATCCAACAACAGGTTCGGCCTGGTGGCCCAGCAAATGTTAGCATCCTAAACAATCTGTCACAACATCGACACTCTTTAACAGCAGCTACCTCAATGGGACCTAACATGGGAGCAACACCTATACAAGTGCACATGTCAAACATGATATCGAGTGGCATGACATCAACTTCGGCTGTCATATCTTCTATATCTGGAACAGTACAGCCAATTGGTGCTCAACAGTTGGCACAGAATACAGCTCTCGGTTCTTTTGGGTCAAACACTTCTACTGTATCTTGTAATTCAAATATCGCCGTATCGTCTTCTTTAGCTAACATACAAAGCAACATGGCCATGGGACAATCAGTGCCTTCTATGGCACAAGGTGGTCTGATGGCTGGTCCACAATCAGGACAAGGTGGAATTGGTACGAACCAAAACATGATAAATAACCTTGGGACTACAGCTATCAATTCTACGCCTACAATGATGCCAACACCAGGAATGGTCCAGCAAACAGGAGTAAATGCTCCTAGTGCGAACAACAGTTCTGCTATGAATATGCCTCTGGCACAACATCCTAATGGCCAGCAACCATCGAAGTATGTCAAAATTTGGGAGGGAACTTTGTCTGGGCAAAGGCAAGGACAGCCTGTATTTATTTGTAAACTTGAAGGTTATAGGAGTGGAACAGCGTCTGACACACTTGCTTCAGACTGGCCAGAAACGATGCAGATCGTGCGCCTCATAGCCCAAGAGCATATGAACAACAAGCAGTATGTTGGCAAGGCAGACTTTCTAGTATTTCGGACATTGAATCAGCATGGGTTCCTCGGACAACTACAAGAGAAGAAACTGTGTGCAGTGATTCAGCTACCTTCACAAACTTTGCTGTTGTCAGTGTCTGACAAAGCTGGGCGCCTCATAGGAATGCTGTTCCCAGGGGATATGGTGGTATTCAAACCACAGGTCTCAACTCAGCAGCCACAGATGCAGCCACAGCAGCAGCAGCAGCAGCAGCAGCTACAGCAGCAGCACCACCAAATACAGCAGCAACAGCAGCAACTACAGCAACTGCAACAGCAGCAACTACAACAGCACCAAATGCAAATGCAGCCTCAAGGCCAGCAGCTTCAGCAGCAGCAGCAGATGCAGCAAATGCAACAGCAACAACAACAGATGCAGCAAATGCAACATCAACAACAACAGCAGCAGCAGCAGCAGCAGATTCAACAGCAACAGCAGATGCAGCAGCAGCAGCAGCAACAGCAACAACAGATGCAGCAAATGCAGCAGCAGCAGCAACAGCCTCAACAACTCCAGCAGCAGCCGCAGATGGTGGGTACAGGGATGGGTCAGCAACAATTCATGCAGGGGCATGGTCGGGCGGTGCAGATGATGCAAGGAAAGATCGCGCCACAGGGCCCAGGCAACATGTCTGGAGGAGGCTACCTATCTTGA
CDS Sequence
- >KU030835
ATGGTGGAGGGGATGGCTTCGGAGAGGCAGCTGGTGGTGGTCGTTGAGGGCACGGCGGCGCTGGGGCCGTACTGGCCCGCCATTGCGGCCGAGTACGTCGAGAAGATCGTTCGGAGTTTTTGTTCTACTGAACTATCAGGGCAGAAGCTTGCAGGGGTACCACCTGAGCTTGCATTAGTTGTCTTCCATACCCACGGACCATACAGTGCCTTTATTGTACAACGCAGCGGTTGGACAAAAGATATGGATGCTTTTCTTTCATGGTTATCAGGAATATCATTTAGTGGTGGAGGCTTCAGTGAAGCTGCTATTTGTGAAGGTCTTGCTGAAGCACTGATGATACTCCAAGGCAGTTCTAGTAGCAGCCAGAATCATCAAAATCGTGAACTTCAAAAGCATTGCCTACTTGTTGCTGCAAGTAATCCTTACCCGCTGCCTACACCTGTCTACCGCCCTTCTGTTCAAAGTAGTGATCACAAAAAGAGCAACGAAGCAACAAAGGAATCATGTCTTGCTGATGCTGAGGCTGTTGCAGTCTCATTTGCTCAGTGCTCTGTGTCATTGTCGGTGGTATCTCCTAAACAGCTACCAACACTGAAGGCAATATACAACGCGGGAAAGAGGAATCCTCAAGCTTCTGATCCATCAGTTGATCATGCCAAAAATCCACATTTTCTTGTTTTGCTCTCTGAGAGTTTCATGGAGGCTCGAACAGCTCTAAGCCATCCTTTACCCGGGAACCTTGTCCCAAACCACACCATTACAAAAATGGATACCACACCTGCAGCTACTGTGCCAGGACCACCTTCGAATGCCAGTCCCTCAGTGAATGGAACGATGATGGGACGGCAACCGACTGCAAATGTTAAAGTGGAGCCAACAACTATACCACCAATGGTTTCTGCACCTGCATTCTCTCATATGACACCTATTTCAAATGTTGCTTCTCAAGGTGTATCAGCAATGCAAACTTCTTCACCATCGATTATTTCACAAGAAACAAATGTTGCAAATGAAATATTGCAAGAGCATAAGCCTTTAGTAAACCCTATCCAACAACAGGTTCGGCCTGGTGGCCCAGCAAATGTTAGCATCCTAAACAATCTGTCACAACATCGACACTCTTTAACAGCAGCTACCTCAATGGGACCTAACATGGGAGCAACACCTATACAAGTGCACATGTCAAACATGATATCGAGTGGCATGACATCAACTTCGGCTGTCATATCTTCTATATCTGGAACAGTACAGCCAATTGGTGCTCAACAGTTGGCACAGAATACAGCTCTCGGTTCTTTTGGGTCAAACACTTCTACTGTATCTTGTAATTCAAATATCGCCGTATCGTCTTCTTTAGCTAACATACAAAGCAACATGGCCATGGGACAATCAGTGCCTTCTATGGCACAAGGTGGTCTGATGGCTGGTCCACAATCAGGACAAGGTGGAATTGGTACGAACCAAAACATGATAAATAACCTTGGGACTACAGCTATCAATTCTACGCCTACAATGATGCCAACACCAGGAATGGTCCAGCAAACAGGAGTAAATGCTCCTAGTGCGAACAACAGTTCTGCTATGAATATGCCTCTGGCACAACATCCTAATGGCCAGCAACCATCGAAGTATGTCAAAATTTGGGAGGGAACTTTGTCTGGGCAAAGGCAAGGACAGCCTGTATTTATTTGTAAACTTGAAGGTTATAGGAGTGGAACAGCGTCTGACACACTTGCTTCAGACTGGCCAGAAACGATGCAGATCGTGCGCCTCATAGCCCAAGAGCATATGAACAACAAGCAGTATGTTGGCAAGGCAGACTTTCTAGTATTTCGGACATTGAATCAGCATGGGTTCCTCGGACAACTACAAGAGAAGAAACTGTGTGCAGTGATTCAGCTACCTTCACAAACTTTGCTGTTGTCAGTGTCTGACAAAGCTGGGCGCCTCATAGGAATGCTGTTCCCAGGGGATATGGTGGTATTCAAACCACAGGTCTCAACTCAGCAGCCACAGATGCAGCCACAGCAGCAGCAGCAGCAGCAGCAGCTACAGCAGCAGCACCACCAAATACAGCAGCAACAGCAGCAACTACAGCAACTGCAACAGCAGCAACTACAACAGCACCAAATGCAAATGCAGCCTCAAGGCCAGCAGCTTCAGCAGCAGCAGCAGATGCAGCAAATGCAACAGCAACAACAACAGATGCAGCAAATGCAACATCAACAACAACAGCAGCAGCAGCAGCAGCAGATTCAACAGCAACAGCAGATGCAGCAGCAGCAGCAGCAACAGCAACAACAGATGCAGCAAATGCAGCAGCAGCAGCAACAGCCTCAACAACTCCAGCAGCAGCCGCAGATGGTGGGTACAGGGATGGGTCAGCAACAATTCATGCAGGGGCATGGTCGGGCGGTGCAGATGATGCAAGGAAAGATCGCGCCACAGGGCCCAGGCAACATGTCTGGAGGAGGCTACCTATCTTGA
Protein Sequence
- >KU030835
MVEGMASERQLVVVVEGTAALGPYWPAIAAEYVEKIVRSFCSTELSGQKLAGVPPELALVVFHTHGPYSAFIVQRSGWTKDMDAFLSWLSGISFSGGGFSEAAICEGLAEALMILQGSSSSSQNHQNRELQKHCLLVAASNPYPLPTPVYRPSVQSSDHKKSNEATKESCLADAEAVAVSFAQCSVSLSVVSPKQLPTLKAIYNAGKRNPQASDPSVDHAKNPHFLVLLSESFMEARTALSHPLPGNLVPNHTITKMDTTPAATVPGPPSNASPSVNGTMMGRQPTANVKVEPTTIPPMVSAPAFSHMTPISNVASQGVSAMQTSSPSIISQETNVANEILQEHKPLVNPIQQQVRPGGPANVSILNNLSQHRHSLTAATSMGPNMGATPIQVHMSNMISSGMTSTSAVISSISGTVQPIGAQQLAQNTALGSFGSNTSTVSCNSNIAVSSSLANIQSNMAMGQSVPSMAQGGLMAGPQSGQGGIGTNQNMINNLGTTAINSTPTMMPTPGMVQQTGVNAPSANNSSAMNMPLAQHPNGQQPSKYVKIWEGTLSGQRQGQPVFICKLEGYRSGTASDTLASDWPETMQIVRLIAQEHMNNKQYVGKADFLVFRTLNQHGFLGQLQEKKLCAVIQLPSQTLLLSVSDKAGRLIGMLFPGDMVVFKPQVSTQQPQMQPQQQQQQQQLQQQHHQIQQQQQQLQQLQQQQLQQHQMQMQPQGQQLQQQQQMQQMQQQQQQMQQMQHQQQQQQQQQQIQQQQQMQQQQQQQQQQMQQMQQQQQQPQQLQQQPQMVGTGMGQQQFMQGHGRAVQMMQGKIAPQGPGNMSGGGYLS