Gene Details:

• Gene ID:
• Gene Symbol: TaMED25-A
• Gene Name: Mediator subunit 25
• Genome: Chinese_Spring1.0
• Species: Triticum aestivum

Functional Descriptions:

• The Wheat Mediator Subunit TaMED25 Interacts with the Transcription Factor TaEIL1 to Negatively Regulate Disease Resistance against Powdery Mildew.
• Report the function and molecular mechanism of the bread wheat Mediator subunit 25 (TaMED25) in regulating the bread wheat immune response signaling pathway.
• Knockdown of TaMED25 by barley stripe mosaic virus-induced gene silencing reduced bread wheat susceptibility to the powdery mildew fungus during the compatible plant-pathogen interaction.
• TaMED25 and TaEIL1 synergistically activate ETHYLENE RESPONSE FACTOR1 (TaERF1) transcription to modulate bread wheat basal disease resistance to B. graminis f. sp. tritici by repressing the expression of pathogenesis-related genes and deterring the accumulation of reactive oxygen species.

Function-related keywords:

• transcription-factor ,  resistance ,  disease ,  disease-resistance ,  ethylene ,  pathogen ,  immune-response ,  signaling-pathway-gene ,  reactive-oxygen-species ,  ethylene-response ,  pathogen-resistance ,  powdery-mildew ,  mildew-resistance ,  mildew ,  powdery-mildew-resistance ,  virus

Literature:

• The Wheat Mediator Subunit TaMED25 Interacts with the Transcription Factor TaEIL1 to Negatively Regulate Disease Resistance against Powdery Mildew.   DOI:  10.1104/pp.15.01784 ;  PMID:  26813794

Related News:

Gene Resources:

• NCBI ID: KU030834
• UniProt accessions: A0A146BA26

Orthologs:

Sequences: