Gene Details:

  • Gene ID:
  • Gene Symbol: TaKCS6-B
  • Gene Name: 3-ketoacyl-CoA synthase 6-B
  • Genome: Chinese_Spring1.0
  • Species: Triticum aestivum

Functional Descriptions:

  • Identified wheat 3-KETOACYL-CoA SYNTHASE (TaKCS6), a homolog of barley HvKCS6, as a key enzyme in the biosynthesis of wheat cuticular wax.
  • TaKCS6 as a key regulator in the biosynthesis of the cuticular wax that is required for Bgt germination in bread wheat.
  • We further identified very-long-chain aldehydes as the signals provided by the TaCHR729-TaKPAB1-TaKCS6 signaling module for stimulation of Bgt germination. This study reveals a crucial role for chromatin remodeling factors in regulating the interaction between wheat and powdery mildew and demonstrates a direct link between histone modification and cuticular wax biosynthesis in wheat.
  • Cuticular wax deposition and Bgt germination are impeded on the leaves of TaKCS6-knockdown wheat.
  • Application of wild-type cuticular wax or VLC aldehydes restores Bgt germination on leaves of TaCHR729-, TaKPAB1-, and TaKCS6-knockdown plants.

Literature:

Gene Resources:

Orthologs:

Sequences:

cDNA Sequence
  • >MH665385
    ATGCCGAGCGCGCTGGGGAGCGGCTTCGCCGGGTCGGTGAAGCTCAAGTACGTGAAGCTGGGGTACCAGTACCTGGTGAACCACTTCCTGACGCTGCTGCTGGTGCCGGTCATGGCGGCCACGGCGATCGAGCTGGCGCGCCTCGGCCCCGGCGAGCTGCTCACGCTCTGGCGCTCCCTCGACCTCGACCTCGTGCACATCCTCTGCTCCGCCTTCCTCGTCGTCTTCGTCGCCACCGTCTACTTCATGTCGCGCCCCAGGCCCGTCTTCCTCGTCGACTACTGCTGCTACAAGCCCTCCCCCAGCTTCCGGGTGCCCTTCACCACCTTCATGGAGCACATCAAGCTCATCTCCAACAACGACAAGAGCCTGCGCTTCCAGACACGCATCCTCGAGCGCTCCGGCCTCGGGGAGGAGACCTGCCTCCCACCGGCCAACCACTACATCCCGCCCAACCCCAGCATGGAGGCGTCCCGCGCCGAGGCGCAGCTCGTCATCTTCAACGCCATCGACGACCTCGTCCGCCGCACGGGCCTCAAGCCCAAGGACATCGACATCCTCGTCGTCAACTGCAGCCTCTTCTCCCCGACGCCCTCGCTCTCCGCCATGATCATCAACAAGTACAAGCTCCGCAGCAACATCCGCAGCTTCAACCTCTCCGGCATGGGATGCAGCGCCGGGCTCATCTCCATCGACCTCGCGCGCGACATGCTCCAGGTGCATCCCAACTCGAACGCTCTGGTGATCTCGACGGAGATCATCACGCCCAACTTCTACCACGGGAGCCGGCGGGACATGCTGCTGCCCAACTGCCTGTTCCGGATGGGCGCGGCGGCGATCCTGCTGTCCAACCGGCGGCGGGAGGCGCGGCGCGCCAAGTACAGGCTGGTGCACGTGGTGCGCACGCACAAGGGCGCGGACGACCGCGCGTACCGGTGTGTGTACGAGGAGGAGGACGACGAGGGGCACTCGGGCATCTCGCTCTCCAAGGAGCTCATGGCCATCGCCGGCGAGGCGCTCAAGTCCAACATCACCACCATGGGCCCGCTGGTGCTGCCCATGTCGGAGCAGCTGCTCTTCTTCTTCCGCCTCGTCGGGCGCAAGGTGATCAACAACAAGTGGAAGCCCTACATCCCGGACTTCAAGCTGGCGTTCGAGCACTTCTGCATCCACGCCGGCGGGCGCGCCGTCATCGACGAGCTGCATAAGAACCTGGAGCTGTCGCCGCGGCACGTGGAGGCGTCGCGCATGACGCTGCACCGGTTCGGCAACACGTCCAGCAGCTCGCTGTGGTACGAGCTCGCCTACATCGAGGCCAAGGGCCGCATGCGCAAGGGCGACCGCGTGTGGCAGATCGGCTTCGGCAGCGGCTTCAAGTGCAACAGCGCCGTCTGGAAGTGCCTCCGCACCGTCAAGACGCCCACTGACGGGCCCTGGGACGACTGCATCCAGCGCTACCCCGTCCACATCCCGGAGGTCGTCAAGCTGTGA
CDS Sequence
  • >MH665385
    ATGCCGAGCGCGCTGGGGAGCGGCTTCGCCGGGTCGGTGAAGCTCAAGTACGTGAAGCTGGGGTACCAGTACCTGGTGAACCACTTCCTGACGCTGCTGCTGGTGCCGGTCATGGCGGCCACGGCGATCGAGCTGGCGCGCCTCGGCCCCGGCGAGCTGCTCACGCTCTGGCGCTCCCTCGACCTCGACCTCGTGCACATCCTCTGCTCCGCCTTCCTCGTCGTCTTCGTCGCCACCGTCTACTTCATGTCGCGCCCCAGGCCCGTCTTCCTCGTCGACTACTGCTGCTACAAGCCCTCCCCCAGCTTCCGGGTGCCCTTCACCACCTTCATGGAGCACATCAAGCTCATCTCCAACAACGACAAGAGCCTGCGCTTCCAGACACGCATCCTCGAGCGCTCCGGCCTCGGGGAGGAGACCTGCCTCCCACCGGCCAACCACTACATCCCGCCCAACCCCAGCATGGAGGCGTCCCGCGCCGAGGCGCAGCTCGTCATCTTCAACGCCATCGACGACCTCGTCCGCCGCACGGGCCTCAAGCCCAAGGACATCGACATCCTCGTCGTCAACTGCAGCCTCTTCTCCCCGACGCCCTCGCTCTCCGCCATGATCATCAACAAGTACAAGCTCCGCAGCAACATCCGCAGCTTCAACCTCTCCGGCATGGGATGCAGCGCCGGGCTCATCTCCATCGACCTCGCGCGCGACATGCTCCAGGTGCATCCCAACTCGAACGCTCTGGTGATCTCGACGGAGATCATCACGCCCAACTTCTACCACGGGAGCCGGCGGGACATGCTGCTGCCCAACTGCCTGTTCCGGATGGGCGCGGCGGCGATCCTGCTGTCCAACCGGCGGCGGGAGGCGCGGCGCGCCAAGTACAGGCTGGTGCACGTGGTGCGCACGCACAAGGGCGCGGACGACCGCGCGTACCGGTGTGTGTACGAGGAGGAGGACGACGAGGGGCACTCGGGCATCTCGCTCTCCAAGGAGCTCATGGCCATCGCCGGCGAGGCGCTCAAGTCCAACATCACCACCATGGGCCCGCTGGTGCTGCCCATGTCGGAGCAGCTGCTCTTCTTCTTCCGCCTCGTCGGGCGCAAGGTGATCAACAACAAGTGGAAGCCCTACATCCCGGACTTCAAGCTGGCGTTCGAGCACTTCTGCATCCACGCCGGCGGGCGCGCCGTCATCGACGAGCTGCATAAGAACCTGGAGCTGTCGCCGCGGCACGTGGAGGCGTCGCGCATGACGCTGCACCGGTTCGGCAACACGTCCAGCAGCTCGCTGTGGTACGAGCTCGCCTACATCGAGGCCAAGGGCCGCATGCGCAAGGGCGACCGCGTGTGGCAGATCGGCTTCGGCAGCGGCTTCAAGTGCAACAGCGCCGTCTGGAAGTGCCTCCGCACCGTCAAGACGCCCACTGACGGGCCCTGGGACGACTGCATCCAGCGCTACCCCGTCCACATCCCGGAGGTCGTCAAGCTGTGA
Protein Sequence
  • >MH665385
    MPSALGSGFAGSVKLKYVKLGYQYLVNHFLTLLLVPVMAATAIELARLGPGELLTLWRSLDLDLVHILCSAFLVVFVATVYFMSRPRPVFLVDYCCYKPSPSFRVPFTTFMEHIKLISNNDKSLRFQTRILERSGLGEETCLPPANHYIPPNPSMEASRAEAQLVIFNAIDDLVRRTGLKPKDIDILVVNCSLFSPTPSLSAMIINKYKLRSNIRSFNLSGMGCSAGLISIDLARDMLQVHPNSNALVISTEIITPNFYHGSRRDMLLPNCLFRMGAAAILLSNRRREARRAKYRLVHVVRTHKGADDRAYRCVYEEEDDEGHSGISLSKELMAIAGEALKSNITTMGPLVLPMSEQLLFFFRLVGRKVINNKWKPYIPDFKLAFEHFCIHAGGRAVIDELHKNLELSPRHVEASRMTLHRFGNTSSSSLWYELAYIEAKGRMRKGDRVWQIGFGSGFKCNSAVWKCLRTVKTPTDGPWDDCIQRYPVHIPEVVKL