Information report for TaHOS15-B
Gene Details
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Functional Descriptions
- Wheat WD40-repeat protein TaHOS15 functions in a histone deacetylase complex to fine-tune defense responses to Blumeria graminis f.sp. tritici.
- TaHOS15, encoding a WDR protein, from the Bgt-susceptible wheat cultivar Jing411 and demonstrated that knockdown of TaHOS15 expression using virus- or transient-induced gene-silencing attenuated wheat susceptibility to Bgt.
- We determined the role of TaHOS15, which might act as an adaptor protein recruiting TaHDA6 to the chromatin of wheat defense-related genes including TaPR1, TaPR2, TaPR5, and TaWRKY45, where they repress histone acetylation.
- Reduced TaHOS15 or TaHDA6 transcript levels led to decreased susceptibility to Bgt together with enhanced defense-related transcription under Bgt infection.
- TaHOS15 functions in a histone deacetylase complex with TaHDA6 to fine-tune the defense response to Bgt in common wheat.
Functional Keywords
- defense-response , defense , virus , protein
Literature and News
Gene Resources
- NCBI ID: MH556920
- UniProt accessions: A0A385MK49
- EMBL: MH556920
- AlphaFoldDB: A0A385MK49
- GO: GO:0003714 , GO:0005634
- InterPro: IPR001680 , IPR006594 , IPR015943 , IPR019775 , IPR020472 , IPR036322 , IPR045183
- PANTHER: PTHR22846 , PTHR22846:SF2
- SUPFAM: SSF50978
- PROSITE: PS00678 , PS50082 , PS50294 , PS50896
- Gene3D: 1.20.960.30 , 2.130.10.10
- CDD: cd00200
Sequences
cDNA Sequence
- >MH556920
ATGGGAGCGATAACCTCGGCGGAGCTCAACTTCCTCGTCTTCCGCTACCTACAGGAGTCCGGTTTTGTTCATGCCGCATTTACTTTAGGGTATGAAGCAGGGATACATAAAGGTGGGATAGATGGAAATGTTGTCCCTCCTGGCGCTCTTATCACTATCGTGCAGAAAGGCCTCCAGTACATAGAATTAGAAGCAAATACTGATGAAAATGATCAAGAAGTTGAGAAGGATTTTGCTCTTCTGGAACCTCTTGAAATCATCACAAAAGATGTTGAAGAGTTGCAACAGATTGTGAAGAAGAGAAAAAGGGAGAGGCTTCAAATTGATTCTGACAAGGACAAGGGGAAAGCGAAAGAGTGCATCGAGGAGCATGAACATCGTCTTGGTGGTGAACGGGAGAGAGAGCGCCATGACAAAGAAAAAGACCAAGAGATGGAAAAAGATAGAACTGAAAGAGACAAGGTGCAAGAGAAAGAGAAGGAAAGGGAAAAACAACACACAGAGCATATTGATAAGGTTAAGCACGAAGAGGATCCCCTTGCCAGTGGAGGTCCTAAACCAATGGATGTAAGTACAACTCATGAAATTTTTAGTGCGGATGTAACCGTTTTGGAAGGACACAGTTCAGAGGTTTTTGCTTGTGCATGGAGTCCAGCTGGTTCTCTTCTAGCTTCTGGGTCAGGAGACTCGACTGCTAGAATTTGGACAATTGCTGATGGTCCATGTGGTTCCATTCAATCCTCTCCTGCAAGTGTTCATGTTTTGAAACATTTTAAGGGTAGGACCAACGAGAAGAGCAAGGATGTCACCACACTTGACTGGAATGGGGAAGGAACACTATTGGCCACGGGCTCCTATGATGGCCAGGCAAGAATATGGAGTAGGGACGGAGAGTTAAAGCAAACTTTATTCAAACACAAGGGACCTATATTTTCTTTGAAATGGAATAGGAAAGGTGATTTTCTTCTAAGTGGCAGCGTAGACAAAACTGCTATTGTCTGGGATACAAAGACATGGGAGTGCAAGCAGCAATTTGAATTTCATTCAGCTCCAACACTAGATGTTGATTGGCGAAACAACAACTCTTTTGCAACATGCTCAACTGATAACATGATCTATGTTTGCAAGATTGGGGATCCACGCCCAGTTAAAACATTCAGTGGCCATCAAAGTGAAGTTAATGCTATCAAGTGGGATCCAACTGGTTCTTTGTTGGCTTCTTGTTCTGATGATTGGACTGCAAAGATATGGAGTGTGAAGCAGGACAAATGTGTATATGATTTTAAAGAGCATACCAAGGAAATATACACTATTAGATGGAGCCCCACAGGTCCAGGAACAAATAATCCCAATCAACAGCTGCTTTTGGCAAGCGCATCGTTTGATTCATCTATCAAGCTATGGGAAGTTGAGAAAGGACACCTTCTGTACAGCTTGGCTGGCCATAGGCAGCCAGTTTATTCTGTGGCCTTTAGCCCTGATGGTGAGTACCTGGCTAGTGGGTCGCTGGATCAAAGCCTACATATATGGTCCGTCAAAGAAGGCAGGATCCTGAAGACCTTCAGAGGGAGCGGTGGCATTTTTGAAGTGTGCTGGAACAAAGAAGGCAGCAAGATAGCAGCTTGCTTCTCCAACAATACTGTCTGCGTCATGGATTTCAGGATGTAG
CDS Sequence
- >MH556920
ATGGGAGCGATAACCTCGGCGGAGCTCAACTTCCTCGTCTTCCGCTACCTACAGGAGTCCGGTTTTGTTCATGCCGCATTTACTTTAGGGTATGAAGCAGGGATACATAAAGGTGGGATAGATGGAAATGTTGTCCCTCCTGGCGCTCTTATCACTATCGTGCAGAAAGGCCTCCAGTACATAGAATTAGAAGCAAATACTGATGAAAATGATCAAGAAGTTGAGAAGGATTTTGCTCTTCTGGAACCTCTTGAAATCATCACAAAAGATGTTGAAGAGTTGCAACAGATTGTGAAGAAGAGAAAAAGGGAGAGGCTTCAAATTGATTCTGACAAGGACAAGGGGAAAGCGAAAGAGTGCATCGAGGAGCATGAACATCGTCTTGGTGGTGAACGGGAGAGAGAGCGCCATGACAAAGAAAAAGACCAAGAGATGGAAAAAGATAGAACTGAAAGAGACAAGGTGCAAGAGAAAGAGAAGGAAAGGGAAAAACAACACACAGAGCATATTGATAAGGTTAAGCACGAAGAGGATCCCCTTGCCAGTGGAGGTCCTAAACCAATGGATGTAAGTACAACTCATGAAATTTTTAGTGCGGATGTAACCGTTTTGGAAGGACACAGTTCAGAGGTTTTTGCTTGTGCATGGAGTCCAGCTGGTTCTCTTCTAGCTTCTGGGTCAGGAGACTCGACTGCTAGAATTTGGACAATTGCTGATGGTCCATGTGGTTCCATTCAATCCTCTCCTGCAAGTGTTCATGTTTTGAAACATTTTAAGGGTAGGACCAACGAGAAGAGCAAGGATGTCACCACACTTGACTGGAATGGGGAAGGAACACTATTGGCCACGGGCTCCTATGATGGCCAGGCAAGAATATGGAGTAGGGACGGAGAGTTAAAGCAAACTTTATTCAAACACAAGGGACCTATATTTTCTTTGAAATGGAATAGGAAAGGTGATTTTCTTCTAAGTGGCAGCGTAGACAAAACTGCTATTGTCTGGGATACAAAGACATGGGAGTGCAAGCAGCAATTTGAATTTCATTCAGCTCCAACACTAGATGTTGATTGGCGAAACAACAACTCTTTTGCAACATGCTCAACTGATAACATGATCTATGTTTGCAAGATTGGGGATCCACGCCCAGTTAAAACATTCAGTGGCCATCAAAGTGAAGTTAATGCTATCAAGTGGGATCCAACTGGTTCTTTGTTGGCTTCTTGTTCTGATGATTGGACTGCAAAGATATGGAGTGTGAAGCAGGACAAATGTGTATATGATTTTAAAGAGCATACCAAGGAAATATACACTATTAGATGGAGCCCCACAGGTCCAGGAACAAATAATCCCAATCAACAGCTGCTTTTGGCAAGCGCATCGTTTGATTCATCTATCAAGCTATGGGAAGTTGAGAAAGGACACCTTCTGTACAGCTTGGCTGGCCATAGGCAGCCAGTTTATTCTGTGGCCTTTAGCCCTGATGGTGAGTACCTGGCTAGTGGGTCGCTGGATCAAAGCCTACATATATGGTCCGTCAAAGAAGGCAGGATCCTGAAGACCTTCAGAGGGAGCGGTGGCATTTTTGAAGTGTGCTGGAACAAAGAAGGCAGCAAGATAGCAGCTTGCTTCTCCAACAATACTGTCTGCGTCATGGATTTCAGGATGTAG
Protein Sequence
- >MH556920
MGAITSAELNFLVFRYLQESGFVHAAFTLGYEAGIHKGGIDGNVVPPGALITIVQKGLQYIELEANTDENDQEVEKDFALLEPLEIITKDVEELQQIVKKRKRERLQIDSDKDKGKAKECIEEHEHRLGGERERERHDKEKDQEMEKDRTERDKVQEKEKEREKQHTEHIDKVKHEEDPLASGGPKPMDVSTTHEIFSADVTVLEGHSSEVFACAWSPAGSLLASGSGDSTARIWTIADGPCGSIQSSPASVHVLKHFKGRTNEKSKDVTTLDWNGEGTLLATGSYDGQARIWSRDGELKQTLFKHKGPIFSLKWNRKGDFLLSGSVDKTAIVWDTKTWECKQQFEFHSAPTLDVDWRNNNSFATCSTDNMIYVCKIGDPRPVKTFSGHQSEVNAIKWDPTGSLLASCSDDWTAKIWSVKQDKCVYDFKEHTKEIYTIRWSPTGPGTNNPNQQLLLASASFDSSIKLWEVEKGHLLYSLAGHRQPVYSVAFSPDGEYLASGSLDQSLHIWSVKEGRILKTFRGSGGIFEVCWNKEGSKIAACFSNNTVCVMDFRM