Gene Details:

• Gene ID: TraesCS2D02G235100
• Gene Symbol: TaHOS15-A
• Gene Name: WD40-repeat protein A
• Genome: Chinese_Spring1.0
• Species: Triticum aestivum

Functional Descriptions:

• Wheat WD40-repeat protein TaHOS15 functions in a histone deacetylase complex to fine-tune defense responses to Blumeria graminis f.sp. tritici.
• TaHOS15, encoding a WDR protein, from the Bgt-susceptible wheat cultivar Jing411 and demonstrated that knockdown of TaHOS15 expression using virus- or transient-induced gene-silencing attenuated wheat susceptibility to Bgt.
• We determined the role of TaHOS15, which might act as an adaptor protein recruiting TaHDA6 to the chromatin of wheat defense-related genes including TaPR1, TaPR2, TaPR5, and TaWRKY45, where they repress histone acetylation.
• Reduced TaHOS15 or TaHDA6 transcript levels led to decreased susceptibility to Bgt together with enhanced defense-related transcription under Bgt infection.
• TaHOS15 functions in a histone deacetylase complex with TaHDA6 to fine-tune the defense response to Bgt in common wheat.

Function-related keywords:

• defense-response ,  defense ,  virus ,  protein

Literature:

• Wheat WD40-repeat protein TaHOS15 functions in a histone deacetylase complex to fine-tune defense responses to Blumeria graminis f.sp. tritici.   DOI:  10.1093/jxb/ery330 ;  PMID:  30204899

Related News:

Gene Resources:

• NCBI ID: MH556919
• UniProt accessions: A0A3B6DB31

Orthologs:

Sequences: