Information report for TaGW2-A
Gene Details
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Functional Descriptions
- TaDA1, a conserved negative regulator of kernel size, has an additive effect with TaGW2 in common wheat.
- The simultaneous silencing of TaDA1 and TaGW2 has an additive effect on kernel size and weight.
- TaDA1 and TaGW2 function in partially overlapping but relatively independent protein networks.
- A comparative proteome analysis of developing transgenic and wild-type grains indicated that TaDA1 and TaGW2 are involved in partially overlapping but relatively independent protein regulatory networks.
- TaDA1 and TaGW2 act relatively independently of each other; for example, several proteins related to cell proliferation and cell expansion were significantly up-regulated in GW2-Ri-3.
- The E3 ligase TaGW2 regulates drought resistance in wheat.
- TaGW2 homoeologs also affect grain protein content as this parameter was generally increased in the mutants, especially in the lines lacking two or three homoeologs.
- Down-regulation of the TaGW2 gene by RNA interference results in decreased grain size and weight in wheat.
- TaGW2-6A allelic variation contributes to grain size possibly by regulating the expression of cytokinins and starch-related genes in wheat.
- Functional allelic variants of TaGW2-6A produce large grains, possibly via changes in endosperm cells and dry matter by regulating the expression of cytokinins and starch-related genes via the ubiquitin-proteasome system.
- The E3 ligase TaGW2 mediates transcription factor TaARR12 degradation to promote drought resistance in wheat.
Functional Keywords
Literature and News
- TaDA1, a conserved negative regulator of kernel size, has an additive effect with TaGW2 in common wheat (Triticum aestivum L). DOI: 10.1111/pbi.13298 ; PMID: 31733093
- Less water, more seeds? The E3 ligase TaGW2 regulates drought resistance in wheat. DOI: 10.1093/plcell/koad311 ; PMID: 38109462
- Analysis of the functions of TaGW2 homoeologs in wheat grain weight and protein content traits. DOI: 10.1111/tpj.13903 ; PMID: 29570880
- Down-regulation of the TaGW2 gene by RNA interference results in decreased grain size and weight in wheat. DOI: 10.1093/jxb/ers249 ; PMID: 22996678
- TaGW2-6A allelic variation contributes to grain size possibly by regulating the expression of cytokinins and starch-related genes in wheat. DOI: 10.1007/s00425-017-2759-8 ; PMID: 28825220
- The E3 ligase TaGW2 mediates transcription factor TaARR12 degradation to promote drought resistance in wheat. DOI: 10.1093/plcell/koad307 ; PMID: 38079275
Gene Resources
- NCBI ID: 100682452
- UniProt accessions: A0A097ET43
- EMBL: KJ697754
- EnsemblPlants: TraesCS6A02G189300.1
- Gramene: TraesCS6A02G189300.1
- GO: GO:0008270
- OMA: FIMEARY
- ExpressionAtlas: TraesCS6A02G189300
- InterPro: IPR001841 , IPR039301
- PANTHER: PTHR31315 , PTHR31315:SF1
- SUPFAM: SSF57850
- PROSITE: PS50089
Homologs
- Oryza sativa: GW2;OsGW2
Sequences
cDNA Sequence
- >TraesCS6A02G189300.1
GAGGGGAAATGCATTTTTAAAAACAGGGTAATCCCACCTCGCCTCGGCGCTCCCCAAGCCCCGCAGCATCGCGTACGAGTGCGTATACCGTATGTATCTACAGTGAGGCGGCGCGGGGCAAGGGTTTCGTCTCCGGCGGCGGCGACGGCGGCGGCGGCGGCGGAGGAGGCTAGATCTGGGAGGGATGGGGAACAGAATAGGAGGGAGGAGGAAGGCCGGGGTGGAGGAGCGGTACACGAGGCCGCAGGGGCTGTACGAGCACAGGGATATCGACCAGAAGAAGCTACGCAAGTTGATCCTCGAGGCCAAGCTCGCGCCCTGCTACCCGGGGGCTGACGACGCCGCGGGGGGTGACCTGGAGGAGTGCCCCATCTGCTTCCTGTACTACCCAAGCCTTAACCGATCAAAATGTTGCTCGAAAGGGATATGTACAGAGTGCTTTCTTCAAATGAAACCAACTCATACTGCTCGACCTACACAATGCCCATTCTGCAAAACCCCCAACTATGCTGTGGAGTATCGTGGTGTAAAGACAAAGGAGGAAAGGAGCATAGAGCAATTTGAAGAACAGAAAGTCATTGAAGCACAGATGAGGGTGCGGCAGCAAGCACTTCAAGACGAAGAGGATAAGATGAAAAGAAAACAGAGTAGGTGCTCTTCTAGCAGAACAATCGCTCCAACAACAGAAGTGGAGTATCGAGATATTTGCAGCACATCCTATTCAGTGCCATCGTACCAATGTACCCAGCAAGAAACTGAATGTTGTTCGTCTGAGCCTTCATGTTCTGCTCAGGCTAACATGCGGTCTTTCCATTCTAGGCATACTCGTGATGATAACATAGACATGAACATAGAGGACATGATGGTTATGGAAGCGATTTGGCGTTCAATTCAGGAGCAAGGAAGTATAGGAAATCCTTCTTGTGGGAGCTTTATGCCTTTTGAGCAACCAACGCGTGAGAGGCAGGCATTCGTTGCAGCTCCTCCTCTAGAAATGCCCCATCCTGGTGGATTTTCTTGTGCTGTTGCTGCTATGGCTGAGCACCAGCCATCAAGCATGGATTTCTCTTACATGACTGGTAGTAGTGCGTTCCCAGTCTTTGACATGTTCCGCCGACCGTGCAACATTGCTGGTGGAAGCATGGGTGCTGCGGAAAGTTCACCAGATAGCTGGAGCGGGATAGCGCCAAGTTGCAGCAGAAGGGAAGTGGTAAGAGAGGAAGGAGAGTGCTCAACCGACCACTTGTCAGAGGGTGCAGAGGCCGGGACAAGCTATGCCGGCTCGGACATTGTGGTGGATGCGGGGACAATGCTACCGTTGCCTTTTGCTGACAATTACAGTATGGTTGCAAGCCATTTCCGTCCTGAGAGCATCGAAGAACAAATGATGTATTCCATGGCTGTTTCTTTAGCAGAAGCTCATGGTAGAACGCACACGCAAGGGTTGGCATGGTTGTAACGCGATGATTGTGACGTTTACTGCCTTCTCTCCCGCACTATCGTTGTTCTGCCCCCCTTCTGCTCTTTTTTGCCACCCCGTGTTCGGCCGTTTTGTTTCTCCTTTTTGCATGTGTTGCATCATGGTTTGATATAGTTCCCGCTATAGCTCTCCATTATTGCTTATATGTTGTAAAATGGAATATGAGGAAGAAATAGAAAAGAGAATGAGTCAGTGTTCTTGATGCCAAAAGAAGGATGCAAAAATGTTT
CDS Sequence
- >TraesCS6A02G189300.1
ATGGGGAACAGAATAGGAGGGAGGAGGAAGGCCGGGGTGGAGGAGCGGTACACGAGGCCGCAGGGGCTGTACGAGCACAGGGATATCGACCAGAAGAAGCTACGCAAGTTGATCCTCGAGGCCAAGCTCGCGCCCTGCTACCCGGGGGCTGACGACGCCGCGGGGGGTGACCTGGAGGAGTGCCCCATCTGCTTCCTGTACTACCCAAGCCTTAACCGATCAAAATGTTGCTCGAAAGGGATATGTACAGAGTGCTTTCTTCAAATGAAACCAACTCATACTGCTCGACCTACACAATGCCCATTCTGCAAAACCCCCAACTATGCTGTGGAGTATCGTGGTGTAAAGACAAAGGAGGAAAGGAGCATAGAGCAATTTGAAGAACAGAAAGTCATTGAAGCACAGATGAGGGTGCGGCAGCAAGCACTTCAAGACGAAGAGGATAAGATGAAAAGAAAACAGAGTAGGTGCTCTTCTAGCAGAACAATCGCTCCAACAACAGAAGTGGAGTATCGAGATATTTGCAGCACATCCTATTCAGTGCCATCGTACCAATGTACCCAGCAAGAAACTGAATGTTGTTCGTCTGAGCCTTCATGTTCTGCTCAGGCTAACATGCGGTCTTTCCATTCTAGGCATACTCGTGATGATAACATAGACATGAACATAGAGGACATGATGGTTATGGAAGCGATTTGGCGTTCAATTCAGGAGCAAGGAAGTATAGGAAATCCTTCTTGTGGGAGCTTTATGCCTTTTGAGCAACCAACGCGTGAGAGGCAGGCATTCGTTGCAGCTCCTCCTCTAGAAATGCCCCATCCTGGTGGATTTTCTTGTGCTGTTGCTGCTATGGCTGAGCACCAGCCATCAAGCATGGATTTCTCTTACATGACTGGTAGTAGTGCGTTCCCAGTCTTTGACATGTTCCGCCGACCGTGCAACATTGCTGGTGGAAGCATGGGTGCTGCGGAAAGTTCACCAGATAGCTGGAGCGGGATAGCGCCAAGTTGCAGCAGAAGGGAAGTGGTAAGAGAGGAAGGAGAGTGCTCAACCGACCACTTGTCAGAGGGTGCAGAGGCCGGGACAAGCTATGCCGGCTCGGACATTGTGGTGGATGCGGGGACAATGCTACCGTTGCCTTTTGCTGACAATTACAGTATGGTTGCAAGCCATTTCCGTCCTGAGAGCATCGAAGAACAAATGATGTATTCCATGGCTGTTTCTTTAGCAGAAGCTCATGGTAGAACGCACACGCAAGGGTTGGCATGGTTGTAA
Protein Sequence
- >TraesCS6A02G189300.1
MGNRIGGRRKAGVEERYTRPQGLYEHRDIDQKKLRKLILEAKLAPCYPGADDAAGGDLEECPICFLYYPSLNRSKCCSKGICTECFLQMKPTHTARPTQCPFCKTPNYAVEYRGVKTKEERSIEQFEEQKVIEAQMRVRQQALQDEEDKMKRKQSRCSSSRTIAPTTEVEYRDICSTSYSVPSYQCTQQETECCSSEPSCSAQANMRSFHSRHTRDDNIDMNIEDMMVMEAIWRSIQEQGSIGNPSCGSFMPFEQPTRERQAFVAAPPLEMPHPGGFSCAVAAMAEHQPSSMDFSYMTGSSAFPVFDMFRRPCNIAGGSMGAAESSPDSWSGIAPSCSRREVVREEGECSTDHLSEGAEAGTSYAGSDIVVDAGTMLPLPFADNYSMVASHFRPESIEEQMMYSMAVSLAEAHGRTHTQGLAWL