Gene Details:

Functional Descriptions:

  • TaDA1, a conserved negative regulator of kernel size, has an additive effect with TaGW2 in common wheat.
  • The simultaneous silencing of TaDA1 and TaGW2 has an additive effect on kernel size and weight.
  • TaDA1 and TaGW2 function in partially overlapping but relatively independent protein networks.
  • A comparative proteome analysis of developing transgenic and wild-type grains indicated that TaDA1 and TaGW2 are involved in partially overlapping but relatively independent protein regulatory networks.
  • TaDA1 and TaGW2 act relatively independently of each other; for example, several proteins related to cell proliferation and cell expansion were significantly up-regulated in GW2-Ri-3.
  • The E3 ligase TaGW2 regulates drought resistance in wheat.
  • TaGW2 homoeologs also affect grain protein content as this parameter was generally increased in the mutants, especially in the lines lacking two or three homoeologs.
  • Down-regulation of the TaGW2 gene by RNA interference results in decreased grain size and weight in wheat.
  • TaGW2-6A allelic variation contributes to grain size possibly by regulating the expression of cytokinins and starch-related genes in wheat.
  • Functional allelic variants of TaGW2-6A produce large grains, possibly via changes in endosperm cells and dry matter by regulating the expression of cytokinins and starch-related genes via the ubiquitin-proteasome system.
  • The E3 ligase TaGW2 mediates transcription factor TaARR12 degradation to promote drought resistance in wheat.

Literature:

Gene Resources:

Sequences:

cDNA Sequence
  • >TraesCS6A02G189300.1
    GAGGGGAAATGCATTTTTAAAAACAGGGTAATCCCACCTCGCCTCGGCGCTCCCCAAGCCCCGCAGCATCGCGTACGAGTGCGTATACCGTATGTATCTACAGTGAGGCGGCGCGGGGCAAGGGTTTCGTCTCCGGCGGCGGCGACGGCGGCGGCGGCGGCGGAGGAGGCTAGATCTGGGAGGGATGGGGAACAGAATAGGAGGGAGGAGGAAGGCCGGGGTGGAGGAGCGGTACACGAGGCCGCAGGGGCTGTACGAGCACAGGGATATCGACCAGAAGAAGCTACGCAAGTTGATCCTCGAGGCCAAGCTCGCGCCCTGCTACCCGGGGGCTGACGACGCCGCGGGGGGTGACCTGGAGGAGTGCCCCATCTGCTTCCTGTACTACCCAAGCCTTAACCGATCAAAATGTTGCTCGAAAGGGATATGTACAGAGTGCTTTCTTCAAATGAAACCAACTCATACTGCTCGACCTACACAATGCCCATTCTGCAAAACCCCCAACTATGCTGTGGAGTATCGTGGTGTAAAGACAAAGGAGGAAAGGAGCATAGAGCAATTTGAAGAACAGAAAGTCATTGAAGCACAGATGAGGGTGCGGCAGCAAGCACTTCAAGACGAAGAGGATAAGATGAAAAGAAAACAGAGTAGGTGCTCTTCTAGCAGAACAATCGCTCCAACAACAGAAGTGGAGTATCGAGATATTTGCAGCACATCCTATTCAGTGCCATCGTACCAATGTACCCAGCAAGAAACTGAATGTTGTTCGTCTGAGCCTTCATGTTCTGCTCAGGCTAACATGCGGTCTTTCCATTCTAGGCATACTCGTGATGATAACATAGACATGAACATAGAGGACATGATGGTTATGGAAGCGATTTGGCGTTCAATTCAGGAGCAAGGAAGTATAGGAAATCCTTCTTGTGGGAGCTTTATGCCTTTTGAGCAACCAACGCGTGAGAGGCAGGCATTCGTTGCAGCTCCTCCTCTAGAAATGCCCCATCCTGGTGGATTTTCTTGTGCTGTTGCTGCTATGGCTGAGCACCAGCCATCAAGCATGGATTTCTCTTACATGACTGGTAGTAGTGCGTTCCCAGTCTTTGACATGTTCCGCCGACCGTGCAACATTGCTGGTGGAAGCATGGGTGCTGCGGAAAGTTCACCAGATAGCTGGAGCGGGATAGCGCCAAGTTGCAGCAGAAGGGAAGTGGTAAGAGAGGAAGGAGAGTGCTCAACCGACCACTTGTCAGAGGGTGCAGAGGCCGGGACAAGCTATGCCGGCTCGGACATTGTGGTGGATGCGGGGACAATGCTACCGTTGCCTTTTGCTGACAATTACAGTATGGTTGCAAGCCATTTCCGTCCTGAGAGCATCGAAGAACAAATGATGTATTCCATGGCTGTTTCTTTAGCAGAAGCTCATGGTAGAACGCACACGCAAGGGTTGGCATGGTTGTAACGCGATGATTGTGACGTTTACTGCCTTCTCTCCCGCACTATCGTTGTTCTGCCCCCCTTCTGCTCTTTTTTGCCACCCCGTGTTCGGCCGTTTTGTTTCTCCTTTTTGCATGTGTTGCATCATGGTTTGATATAGTTCCCGCTATAGCTCTCCATTATTGCTTATATGTTGTAAAATGGAATATGAGGAAGAAATAGAAAAGAGAATGAGTCAGTGTTCTTGATGCCAAAAGAAGGATGCAAAAATGTTT
CDS Sequence
  • >TraesCS6A02G189300.1
    ATGGGGAACAGAATAGGAGGGAGGAGGAAGGCCGGGGTGGAGGAGCGGTACACGAGGCCGCAGGGGCTGTACGAGCACAGGGATATCGACCAGAAGAAGCTACGCAAGTTGATCCTCGAGGCCAAGCTCGCGCCCTGCTACCCGGGGGCTGACGACGCCGCGGGGGGTGACCTGGAGGAGTGCCCCATCTGCTTCCTGTACTACCCAAGCCTTAACCGATCAAAATGTTGCTCGAAAGGGATATGTACAGAGTGCTTTCTTCAAATGAAACCAACTCATACTGCTCGACCTACACAATGCCCATTCTGCAAAACCCCCAACTATGCTGTGGAGTATCGTGGTGTAAAGACAAAGGAGGAAAGGAGCATAGAGCAATTTGAAGAACAGAAAGTCATTGAAGCACAGATGAGGGTGCGGCAGCAAGCACTTCAAGACGAAGAGGATAAGATGAAAAGAAAACAGAGTAGGTGCTCTTCTAGCAGAACAATCGCTCCAACAACAGAAGTGGAGTATCGAGATATTTGCAGCACATCCTATTCAGTGCCATCGTACCAATGTACCCAGCAAGAAACTGAATGTTGTTCGTCTGAGCCTTCATGTTCTGCTCAGGCTAACATGCGGTCTTTCCATTCTAGGCATACTCGTGATGATAACATAGACATGAACATAGAGGACATGATGGTTATGGAAGCGATTTGGCGTTCAATTCAGGAGCAAGGAAGTATAGGAAATCCTTCTTGTGGGAGCTTTATGCCTTTTGAGCAACCAACGCGTGAGAGGCAGGCATTCGTTGCAGCTCCTCCTCTAGAAATGCCCCATCCTGGTGGATTTTCTTGTGCTGTTGCTGCTATGGCTGAGCACCAGCCATCAAGCATGGATTTCTCTTACATGACTGGTAGTAGTGCGTTCCCAGTCTTTGACATGTTCCGCCGACCGTGCAACATTGCTGGTGGAAGCATGGGTGCTGCGGAAAGTTCACCAGATAGCTGGAGCGGGATAGCGCCAAGTTGCAGCAGAAGGGAAGTGGTAAGAGAGGAAGGAGAGTGCTCAACCGACCACTTGTCAGAGGGTGCAGAGGCCGGGACAAGCTATGCCGGCTCGGACATTGTGGTGGATGCGGGGACAATGCTACCGTTGCCTTTTGCTGACAATTACAGTATGGTTGCAAGCCATTTCCGTCCTGAGAGCATCGAAGAACAAATGATGTATTCCATGGCTGTTTCTTTAGCAGAAGCTCATGGTAGAACGCACACGCAAGGGTTGGCATGGTTGTAA
Protein Sequence
  • >TraesCS6A02G189300.1
    MGNRIGGRRKAGVEERYTRPQGLYEHRDIDQKKLRKLILEAKLAPCYPGADDAAGGDLEECPICFLYYPSLNRSKCCSKGICTECFLQMKPTHTARPTQCPFCKTPNYAVEYRGVKTKEERSIEQFEEQKVIEAQMRVRQQALQDEEDKMKRKQSRCSSSRTIAPTTEVEYRDICSTSYSVPSYQCTQQETECCSSEPSCSAQANMRSFHSRHTRDDNIDMNIEDMMVMEAIWRSIQEQGSIGNPSCGSFMPFEQPTRERQAFVAAPPLEMPHPGGFSCAVAAMAEHQPSSMDFSYMTGSSAFPVFDMFRRPCNIAGGSMGAAESSPDSWSGIAPSCSRREVVREEGECSTDHLSEGAEAGTSYAGSDIVVDAGTMLPLPFADNYSMVASHFRPESIEEQMMYSMAVSLAEAHGRTHTQGLAWL