Gene Details:

• Gene ID: TraesCS2B02G367600
• Gene Symbol: TaGCN2
• Gene Name: GCN2-type PCR product
• Genome: Chinese_Spring1.0
• Species: Triticum aestivum

Functional Descriptions:

• Overexpression of GCN2-type protein kinase (TaGCN2) in wheat has profound effects on free amino acid concentration and gene expression.
• GCN2-type PCR product (TaGCN2) was amplified from wheat (Triticum aestivum) RNA, while a wheat eIF2α homologue was identified in wheat genome data and found to contain a conserved target site for phosphorylation by GCN2.
• TaGCN2 overexpression in transgenic wheat resulted in significant decreases in total free amino acid concentration in the grain, with free asparagine concentration in particular being much lower than in controls.
• The study demonstrates that TaGCN2 plays an important role in the regulation of genes encoding enzymes of amino acid biosynthesis in wheat and is the first to implicate GCN2-type protein kinases so clearly in sulphur signalling in any organism.
• It shows that manipulation of TaGCN2 gene expression could be used to reduce free asparagine accumulation in wheat grain and the risk of acrylamide formation in wheat products.

Function-related keywords:

• kinase ,  grain ,  protein-kinase ,  grain-protein ,  protein

Literature:

• Overexpression of GCN2-type protein kinase in wheat has profound effects on free amino acid concentration and gene expression.   DOI:  10.1111/j.1467-7652.2011.00665.x ;  PMID:  22070093

Related News:

Gene Resources:

• NCBI ID: FR839672
• UniProt accessions: F4NAR5

Orthologs:

Sequences: