Gene Details:

• Gene ID: TraesCS3B02G591300
• Gene Symbol: TaeIF4E-B
• Gene Name: Eukaryotic initiation factor 4E
• Genome: Chinese_Spring1.0
• Species: Triticum aestivum

Functional Descriptions:

• CRISPR/Cas9-guided knockout of eIF4E improves Wheat yellow mosaic virus resistance without yield penalty.
• The eukaryotic translation initiation factor 4E (eIF4E) is a well-characterized S gene for many potyviruses of the family Potyviridae in dicots, which encodes a cap-binding protein that binds to methylated guanine triggering assembly of the protein translation initiation complex.
• The eIF4E has become a major target for engineering viral resistance using the CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9) genome-editing technology.
• Knocking out eIF4E was shown to result in resistance in dicots such as melon and monocots such as barley.
• The simultaneous targeting of the three TaeIF4E homoeoalleles resulted in pleiotropic changes in plant height and heading/maturity, but without yield penalty.

Function-related keywords:

• resistance ,  yield ,  height ,  plant-height ,  viral-resistance ,  protein-translation

Literature:

• CRISPR/Cas9-guided knockout of eIF4E improves Wheat yellow mosaic virus resistance without yield penalty.   DOI:  10.1111/pbi.14002 ;  PMID:  36628413

Related News:

• PBJ | 中国农科院作科所杨平课题组发现小麦抗病毒新基因

Gene Resources:

• NCBI ID: 543485
• UniProt accessions: P29557

Sequences: