Gene Details:

• Gene ID: TraesCS4D02G118500
• Gene Symbol: TaCIPK14-4D
• Gene Name: TaCIPK14
• Genome: Chinese_Spring1.0
• Species: Triticum aestivum

Functional Descriptions:

• Knockdown of TaCIPK14 significantly increased wheat resistance to Pst, whereas overexpression of TaCIPK14 resulted in enhanced wheat susceptibility to Pst by decreasing different aspects of the defence response, including accumulation of ROS and expression of pathogenesis-relative genes.
• TaCIPK14 acts as an important susceptibility factor in wheat response to Pst.
• Overexpression of TaCIPK14 enhances wheat susceptibility to Pst.
• Simultaneous editing of three homoeologues of TaCIPK14 confers broad-spectrum resistance to stripe rust in wheat.
• These results demonstrate that TaCIPK14 acts as an important susceptibility factor in wheat response to Pst, and knockout of TaCIPK14 represents a powerful strategy for generating new disease-resistant wheat varieties with BSR to Pst.

Function-related keywords:

• resistance ,  disease ,  disease-resistance ,  broad-spectrum-disease-resistance ,  resistant ,  defence ,  defence-response ,  rust-resistance ,  rust

Literature:

• Simultaneous editing of three homoeologues of TaCIPK14 confers broad-spectrum resistance to stripe rust in wheat.   DOI:  10.1111/pbi.13956 ;  PMID:  36326663

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Gene Resources:

• NCBI ID: KAF7053160
• UniProt accessions: A0A3B6JID2

Sequences: