Gene Details:
- Gene ID: TraesCS3A01G143300
- Gene Symbol: TaATX4-A
- Gene Name: Histone-lysine N-methyltransferase
- Genome: Chinese_Spring1.0
- Species: Triticum aestivum
Functional Descriptions:
- Improvement of wheat drought tolerance through editing of TaATX4 by CRISPR/Cas9.
- TaATX4 knockout improves drought tolerance in wheat.
- TaATX4 performs a major role in negatively regulating wheat drought tolerance by orchestrating the transcriptional response to drought stress.
- Treatment with exogenous abscisic acid (ABA) or 20% PEG induced the transcriptional expression of TaATX4 homoeologs, which gradually increased with prolonged treatment time
- The simultaneous triple knockout (KO) of all three TaATX4 homoeologs in wheat to observe the effects on drought tolerance.
Function-related keywords:
- drought , stress , drought-stress , tolerance , aba , drought-tolerance , stress-tolerance , abscisic-acid , stress-response , drought-stress-response , drought-response
Literature:
- Improvement of wheat drought tolerance through editing of TaATX4 by CRISPR/Cas9. DOI: 10.1016/j.jgg.2023.10.001 ; PMID: 37820936
Related News:
Gene Resources:
- NCBI ID: 123060691
- UniProt accessions: A0A3B6ECV7
Sequences:
cDNA Sequence
- >TraesCS3A01G143300
TCAGTTCATGTATCCACGGCAGTTAGGGGCTTTACACAGGCAGGGAACCTTGCGATCCTCCGACTCGTCCGGGTCAAATTTGTAGTCATACCTGTGGATGACAGGGGAAAATAGAGAGGATCAGAACATCAAATGATTGCAGATTGTTGTATACACTCTCAACGCGATTAAATTGTCTTTTTTTCCGTGTGTAAACCAGACAGAAGAGGACAGGGTTATGAAGCAGTACGTCAATTCTTCTCCGGCTGAGACATCTCTTCTGGCAATCAGAATTATCTGGCTCTTGTTGTCGCCGACGCTCACGATCCTCGCGTAGCAGTTAGGCATGCACTGCAAACGCAATGACTATATTAGTTAACCATTTCATGGATTCAAGAAGATGCAGGTGTCAGAGAGCATGATCAAGGTTTACCGAGTGGTTAATTATGCGGGCGATGTTTCCTCTCTCCGTAGCATCAATCACAACATCTTCACTTATTTTGAACAGCTGCAGCAGCACAAGACGCAAAAAAACAATTCAGCACGTCAGAACAACAAAGCTACAGTTTTTATGTGGTTCTACACTTAATCGAATTGTCATCAAGAAAAGATTGCATGACGGCGATTAGTTACACCAGTTAAACCGTTCAAGTTGAAAGTAGGGAACCAATTAAAACAGTACAAAAAGGATAACTCACGTAGCAGTCTTTATTTTCCTTGTGATATCGTGCTTCCCTCAAATCAGCAACACTACGTCTGACTTGGTCCCCACGATATTCGATCACCTGGCACAAGTTTGGTTAGCTGACAAATTAAGAACAGATTCCTCACAAATGGGATGTATTTAAGTGCTTCGATAACATAGGCATAAGCATTTTCATGGTAAAATTTTGAACTCTAGTGTGAGACAGAAAATGTACTAAAAATGTTCATGCTGCTGATTTAACATGTATGTGCCTATAAATTATGCACAACAAACCAATTACATCTACAAATTGGAGATCAAGCATTGCAACCAATTATATTCATTAACTGGAGATCAGTCAATGCAACCAAGTATATTCACTAATTGGAGATCAAGCAAGTAACAAAAGTTATCTGCTGTATTAGACAGTGCACATTTAATCAAATTGCTGCCATAAATGCTACATTGGGCTGTTAAATTATGCTTTGTGACCAGATTAATATGGTATGTCAGTGCATGTGCTTGATAATGTAGTTAGTATGAGCACTGTTGAAGAAAAAAATATAGTCTGCAGTGATTACCATTTGCCCCTCTTGAATTTTCCTAACAGCAAAGAGCCCCCATCCATGTACTCCAGATCGACCACAAGAGACCCTCTTATTTTCAGTTCTCTGAAATAGTCAAACATATGTTTATTGGTTTGCTCATATAGCCTTTTAAGAACCAGGATCATTCAGAAAGTAAACCTGTAAATATTGAAGCCTTTCTTTGAACGTAGCAAAAGGTCGGTCGCCCTTCTGGTCCTGCTGACAAGGGAATAAGATGCCTAAATGTTTCTAGCATTCAAATGTTGCTTAAAAAAAGATGGTGATGGTCAGGACCAGGCACTTACCATGTATGTGTTCAAAGCCTCAATCAAATCTTGAGAGTGGTGTCGGGGTCCCATTATTCGATGGGCAACTGCCTCTCCTTGTTGTTTCTGGAAAACACAGATAATTTAGTACCAAGGACTTGCTGACAAAACAACAGAAATTAAAACTACACAGGTCTGTTAACATCACTTGCATTTAACATTAACCTAAGTTGGGCATAACAGTATGTCACGCAAAACAGTGCTGCTGCAATTTTCAGAATCAACACACACGAACACGCGCACACAACAGGCAAAAAAATTATACAGGAAGGATGAAAAAAAGGTCAATGTATATATTGAGTATAATTGTATAAATGAACTAGAAACGAAAATTATCACAAGGTAATGTCCAGGGTGGATGCAGAAAACCAAGATAATTAGAAAATACCTTGTTTTTCAAGATTTCATAAGGTAGGCACCTTGCAGCTGGGCAATCAGAAACTTCAGCAGGAAAAACCTCCTGGTGATTTTCACTCTTAGCTAGTCTTGCAGGAGATTGTTTCTCATTGTTTTGGAGCAAAAATTTGGTGGAGAACACTCCATCTGGTGTCTTCACTATCAACACATTATCTGGGTCAGGAGTACTGAAGTGGACAAGAAAGAATAACATGTATTAGTAACATTTACTGGTGATAATTTATGCCTCAGGTTACATTTTCACTTCTGCAAATGACATTGTTCCAAAATCATGCCAGTTCCATGGACCATATTTGCCATTGTTTTCTTAAAATAGGTTTGATTGGTACTAAAATCAACCCCAAAAGATTACACAAAAGGAAGTATATATAATGATCGTTAAGCCAGCTTAAAATTGTTCTTCTAGATAACCATTCATGAGTTTAACTTAACCAAAAAGGAAAAATCAAGTGATAGAATTATTACCTGTGAAACGCACAGTAGGAGACCATTTTAGTCACCTTCCTACCATTTCTCTCAGAGTATTGCAACTGCAAGAGTACAGGAAAAGTACAATTTTAATCTTTATGTTTAAAATCGGTTAATAAAGGAACAAACGCCAGAAAATGTTTGCGTCAAATGATGCACAGTTTAAACAGTTGTATCAAGTTATGCTTTAAAGACAGCATGCTTAAAAACTTTAGGATTAGCTCAAATGGAATTATTTGAGCAACGACACAAAAAAAATTGGCACAAGGGAATTTTTGCCACAACATAGCTTAAATGTAAAAGTTGGTGGAAAAAACTTGCTAATCCACAGCAATACTACACAGAAGCAAACAATATCAGGCTGGTAAGTGGCATATGCTCAAACATAATCTTTCAGACAATCATTATATAGCCAATAATATGCATTCTGTTTTCATATAAGAAAAGAGAGTGAAGGTTAAATTAAAGAAAATGGATATGCAAACATATTATGATGACAATTTCCTCTACAAAGAGGTGGCAAAAGCAGTCTACCTCCATGCGATATCCAGCTCTTGATGCACATGTTGCATGATAATAAGTAGAACACTTGTAGCACTGGGTGCAGGCCCCATGCATCTGCTTGCATATGATACATGTCTGGAGTTAACAAAAACACAAGAGTTAAACAAAGAGTAAGATGATTGAACACAGAAGCACATACAATAATTACCCATTAGGCAACCTTGCAAAGAGTACTAGATAAAAATCCTAACCTTCTTAAAGTACTCAGAAGGGATGCTCAATATGCCCACAGCTGGCTCCATTGTCTCGTCAACAGGAAAGGAGACTTTAGGCTGATACCAGGCACACATGACATGAACCCACAGTTGGTCAATATCAGTTGGCTTGAGAGCACCACCTAGGAGGTCCAACAAGAAGTACAAGTTAACAGCATGAGTGATCCATAAACAACATGGTAAATAAGACAAGAAAACATTAGAATATTAGATACCACTGTGGACCAATCAAACTTATCACAACCAAGGAATAAAACTAAGCATGAGTCGGGAACACACTAAAAATGTCAACAGAAGCTGCCCTCTGGTCTAGAGCAGGGGCACTCAGCCTTAGATTGATCTTGCCGACAGCCTGGGACGTCCATTAAACACCCACCTTGTAACTTTACCCTCCTTTGAGGCTGCTGTACTGAACTANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCCCACCCCCACGCCCACCACCGCCACTTTTCAATGAAAAATGAGACGCAAAATCTTATTACGTTTTCTCAGGAAAAAAACGTCAACACTTGAGGAAATTACTGAACTGTCCAAACAATTCCATATGATGAATCATGAAACTATGGAGCACATCAATTGGATCCCTGTTTGGGATGCGGAAACAATGAGGCCCTATTTGGGATACAAGAATTTCACAGGAATTGTTTCATATAGACATTAGGAAAAGAACAAGCATTCCAAACAATGTAGTATAGGATATTCATCGAGACAAAATACCTTTTACAGGGCATAGGCAGCACTCCTTTTTTTGTTGGGGCAGTTCACAAGCTCGACAAACCCAATTAGTTAAATCCTGTACGACACGAGCTCCATAGCACTCTTGATGGACAGCTATTTGACATCTGAATACATAAATTTTCGAGAAGCTTTTATTAACCACTAATCATGAAAACTTACATAATATTTTTAGTCTTCAAACATCAAAGGAATTCAAGTGCAGGTGATGGATAAAAATTCAAATGAAGGCAGGAACTACCTGTTACAAATGATAATTTTGTTGTAGTCCCAATCCTCAACCCACCGACAGACAGCACAACGTTCAGTTGTCCATTTAGCATAGACTGGACTGTAAGAGTTTGCTGCAGATATTGGAAAAATTCAACAGCGTGAAGTCATATTAAAATCACCAACCACAAAGCCCATGAAAAAAAATCAAGAGTGGCATACCTTGTAATGAAAGCAACTCTTCTTTCTTAATGCCTGGGGTAGAAGACTTGAAATTTCCACCCGGAATATCATGAAGCTGCAGATAATGACAAAAAAGGAATCTTGTCAGTTTTGCATGCATGTGTGCATTAGTGTCAACTAGAGATGATACACCGTGCATTGCTGTGGGACTTGGTTGCAATTATTTCGATGAGATTTGATTGTATTAAGTATTAATATTTGGATTAATAATCTGAGAATTGAAACTAATATATTTATTATATTTGATTATTGTATAGTTGTAGAAAAAATATTGAATATGAGTAGCATGCGTGTGGCATGTTAAGGTAGATCTTTTCCCATGCACAGTGGCATGGTCAGTTGGCATAGTTGCATGTTGAGAGAATTGGAGTTAGTGGGGATCAACTAACTAGGTATATATAGCATTCACATATTATGTTGAACCACAGACGTCCAAGTTGATGAAGATCCTGAGAGCTTACCAAGTCAATTAGTGGCTCCCCAGTGCCCTTGAGTTTAATACTCATCTTCCAATTTTTCTTCCTTGAGCCAGTATGCCTCTCCCACTCATTCAGAGTCATCATCTTTTTCTTGCAAGACCTGCATTCACATAATATCCTGCCAGCAAAAACAATACTCAAATACTAATACTGGTGCAACCGTGCAATGATGCAAGCACACATAAGGAAATCAATGCAACATGAAGACCGCTAGCAACTGTGTGATGGTTTTTATTGCTTCTGGCCCCTAAACATCATATGAATTCCCATCACAAAAGTGACCAATCCTAGGGGTGACTACGGTAAGAACTAAAGCGACCTAAAAGTCACTTGCTTATGCACCAAGTGAAGGTTAAAGGACCAATTGCAAGTATACAGTAGCCACTTCGATTCGGTAACATATGTTTGTGCACTTGTACTTTAGCTCTCAGGTCAATTTTTCTAGCCCAGAAAATGAACCAAAAGAGGAAAGTTGCTGCTCCACGAAAAGAAAAGATGGCATGTTTAATAATTTTAGTATTTCTTTCTGAACAGTTGACTTAATACAAAAAAATATAGTACTCCTACTTAAAATAATAAAACATTAGATTCAGATAGAGTATTGATGCAAATTTAAAGAAACATGTAATCTGAAGATTCAGTAGAAGATATGTCAAATGCTTACATGTGCTTTTCTGGCAAGTACAATGCTTCCATCCCAGAGCAGCACACAGGTATGGATTCAGGCAACTTTTCCTTTGAAGTGCTGGCAAATCTATGCTGGGACATGTTAGAAACTGGCATTTTTTATTTATTATAACAGCCAACAGACATCCATAGGTTTGAGAAAGAAATGAATAACTCACTCTGAACTATTGGAGGTGCTCGTTTGTTCAACTTTCATTACTCTCTTGCGTTTAGACTTACAATCAGGACAGAAATACTCGGTATTTTCTAAATCCTGCAAAATAATGTGTAGTCAGTGAAGCCTATCCCTGGAAGCATTGCATATTACATATATATAACAAACATCATGACATTAAAATCTCAACACCAAACAACATATTACATATATATAACAAACATCATGACATTAAAATCTCAACACCAAACAAAGGTGAACAAACAACCTCCAGGTCACTGCATGTCCGGTCGCATTCTACATGAACCCAAATCTGGCACTCATCACAGCATACCTGCCAAGAAACGGATTGCAGGTCAATGCCTACAAAAATCAAGAGAAGATAATCTATATACCATCACCAAAGCGGTTTCAAGGCTTACCCAGTTTCCGCCATCTGTGTGATGCCAAATTTTCTTGCATATGCCACAGTATTGCTTTGACTGCAATAGCTGCAGAAATAATAGTATTTACCCATGTAAGGCACTAAATAGAAATGAATCGAGTTACTAGAACATATGAAGCACCTTCGTTCAGTCACATGCCAGAGACATACATACCTTTTCACAGTGCCTACAAAGTAACTGCTCTGTTTCTTGCTTCTTTTTCTTTGAAATCTTGGATGGAAGACGATTACCGCAGCTATCGCAACATGCTGCTAATTTAACGACAACCTGCAACACAGTAAATAAATTAGATAGCAGCCTAGCCGAGGAACTGTAATAAATGAGGCAGCTACAAGCTCAGCTATTACAACTCCACACGTCCAATTACCTGAGAATGAGATTGACACTCCTGCTCGTTATTAGAACCAGTCACTTCACGTGCGCCATCGGTGACAGACTGCTCATTCACAGACTTGTCCAGAGAGCAGACCCCGTCCATTTGGAGCTCAAAAAAGCCGCGCTCGGCAAGGAAAGCCTCCTCAATTGCTGCACGGAATTTGCTTGGCTTGAGCTTAAGCTTATGGAGAGATTGTCCCTGGAACCTATCTAGGTACTCCACAAAGGGAAAGATCATCCCTTGCTTGACCCATCCATAGTCCTACAAATGAAGACGGTAATGTGAGCCCACGGAAAGAGAAACAGAAAGGAACCGTTTGGTTCATAAACCAACCAATTCAACCAGGAAAAGAGAACTGCAGCGCTTATCCAGGAAACTGTAATAAATAAATTACCCTGTTTTGGCCGCCGGCAGAGTAACCGAAGAACATGACGCAGAGCGCGCCGGGGACGCAAGAGTTGAGCACAACCTCCGGGGCGTGCTGCAGCGGGTTGATCACTAACGCCGGCCACGCGGGGCTCTTCTTCCCCGACCTTGCCCACACCACGTCCCCGAGCACAAAATCCTCTGGCCAGTAGAAATCCTCTCTCCTGACCTCGGCCTCCTGCTTTGGCTTGCACTCCACCACCGGGGACCTCCCCTCCAGCCCGACATTTCCAGTACCAGCATTGCTCGTGGACGGGACCACAGCGCCCACCACGGGCGTCTTCTCCGGCGCGCATTTCTCACCAGCATTGCTCACGGAAGTGACAACGCTTCCACTGAAACAGCCCGAACTGCCGCTCCTGCTGATGTTCCGGCATGCCCGGTACAGCTCCTCCTCCGTCTGCGCGGGCTCGCCGGTCCACACCTCGGTCTGCACGGCCCCAAAGGCGGAGCCTTTCGGGCCGACGGCGCGCACCTCCACCTCGTACACCTGGCCGTCCCTGTCCTCGACCTTGGGCGGCGCGGGGGCCTTGCAGGCCTTCTTGGCGGGCGGCGGCAGGAGGACGGCCGAGTCCCTGAACCGCGAGGGCAGGACGCGCTCCCGGCGGCGCTTGGCGGGCGGCATGCCCTCGGCGGCGGCGGCGGGGGGCTCCAGCTCGTACGGGACGGCGGCGGTGCAGCGCTTGGGCGGGATGCGGGAGGCGAGCAT
CDS Sequence
- >TraesCS3A01G143300
ATGCTCGCCTCCCGCATCCCGCCCAAGCGCTGCACCGCCGCCGTCCCGTACGAGCTGGAGCCCCCCGCCGCCGCCGCCGAGGGCATGCCGCCCGCCAAGCGCCGCCGGGAGCGCGTCCTGCCCTCGCGGTTCAGGGACTCGGCCGTCCTCCTGCCGCCGCCCGCCAAGAAGGCCTGCAAGGCCCCCGCGCCGCCCAAGGTCGAGGACAGGGACGGCCAGGTGTACGAGGTGGAGGTGCGCGCCGTCGGCCCGAAAGGCTCCGCCTTTGGGGCCGTGCAGACCGAGGTGTGGACCGGCGAGCCCGCGCAGACGGAGGAGGAGCTGTACCGGGCATGCCGGAACATCAGCAGGAGCGGCAGTTCGGGCTGTTTCAGTGGAAGCGTTGTCACTTCCGTGAGCAATGCTGGTGAGAAATGCGCGCCGGAGAAGACGCCCGTGGTGGGCGCTGTGGTCCCGTCCACGAGCAATGCTGGTACTGGAAATGTCGGGCTGGAGGGGAGGTCCCCGGTGGTGGAGTGCAAGCCAAAGCAGGAGGCCGAGGTCAGGAGAGAGGATTTCTACTGGCCAGAGGATTTTGTGCTCGGGGACGTGGTGTGGGCAAGGTCGGGGAAGAAGAGCCCCGCGTGGCCGGCGTTAGTGATCAACCCGCTGCAGCACGCCCCGGAGGTTGTGCTCAACTCTTGCGTCCCCGGCGCGCTCTGCGTCATGTTCTTCGGTTACTCTGCCGGCGGCCAAAACAGGGACTATGGATGGGTCAAGCAAGGGATGATCTTTCCCTTTGTGGAGTACCTAGATAGGTTCCAGGGACAATCTCTCCATAAGCTTAAGCTCAAGCCAAGCAAATTCCGTGCAGCAATTGAGGAGGCTTTCCTTGCCGAGCGCGGCTTTTTTGAGCTCCAAATGGACGGGGTCTGCTCTCTGGACAAGTCTGTGAATGAGCAGTCTGTCACCGATGGCGCACGTGAAGTGACTGGTTCTAATAACGAGCAGGAGTGTCAATCTCATTCTCAGGTTGTCGTTAAATTAGCAGCATGTTGCGATAGCTGCGGTAATCGTCTTCCATCCAAGATTTCAAAGAAAAAGAAGCAAGAAACAGAGCAGTTACTTTGTAGGCACTGTGAAAAGCTATTGCAGTCAAAGCAATACTGTGGCATATGCAAGAAAATTTGGCATCACACAGATGGCGGAAACTGGGTATGCTGTGATGAGTGCCAGATTTGGGTTCATGTAGAATGCGACCGGACATGCAGTGACCTGGAGGATTTAGAAAATACCGAGTATTTCTGTCCTGATTGTAAGTCTAAACGCAAGAGAGTAATGAAAGTTGAACAAACGAGCACCTCCAATAGTTCAGACACTTCAAAGGAAAAGTTGCCTGAATCCATACCTGTGTGCTGCTCTGGGATGGAAGCATTGTACTTGCCAGAAAAGCACATGATATTATGTGAATGCAGGTCTTGCAAGAAAAAGATGATGACTCTGAATGAGTGGGAGAGGCATACTGGCTCAAGGAAGAAAAATTGGAAGATGAGTATTAAACTCAAGGGCACTGGGGAGCCACTAATTGACTTGCTTCATGATATTCCGGGTGGAAATTTCAAGTCTTCTACCCCAGGCATTAAGAAAGAAGAGTTGCTTTCATTACAAGCAAACTCTTACAGTCCAGTCTATGCTAAATGGACAACTGAACGTTGTGCTGTCTGTCGGTGGGTTGAGGATTGGGACTACAACAAAATTATCATTTGTAACAGATGTCAAATAGCTGTCCATCAAGAGTGCTATGGAGCTCGTGTCGTACAGGATTTAACTAATTGGGTTTGTCGAGCTTGTGAACTGCCCCAACAAAAAAAGGAGTGCTGCCTATGCCCTGTAAAAGGTGGTGCTCTCAAGCCAACTGATATTGACCAACTGTGGGTTCATGTCATGTGTGCCTGGTATCAGCCTAAAGTCTCCTTTCCTGTTGACGAGACAATGGAGCCAGCTGTGGGCATATTGAGCATCCCTTCTGAGTACTTTAAGAAGACATGTATCATATGCAAGCAGATGCATGGGGCCTGCACCCAGTGCTACAAGTGTTCTACTTATTATCATGCAACATGTGCATCAAGAGCTGGATATCGCATGGAGTTGCAATACTCTGAGAGAAATGGTAGGAAGGTGACTAAAATGGTCTCCTACTGTGCGTTTCACAGTACTCCTGACCCAGATAATGTGTTGATAGTGAAGACACCAGATGGAGTGTTCTCCACCAAATTTTTGCTCCAAAACAATGAGAAACAATCTCCTGCAAGACTAGCTAAGAGTGAAAATCACCAGGAGGTTTTTCCTGCTGAAGTTTCTGATTGCCCAGCTGCAAGGTGCCTACCTTATGAAATCTTGAAAAACAAGAAACAACAAGGAGAGGCAGTTGCCCATCGAATAATGGGACCCCGACACCACTCTCAAGATTTGATTGAGGCTTTGAACACATACATGGACCAGAAGGGCGACCGACCTTTTGCTACGTTCAAAGAAAGGCTTCAATATTTACAGAGAACTGAAAATAAGAGGGTCTCTTGTGGTCGATCTGGAGTACATGGATGGGGGCTCTTTGCTGTTAGGAAAATTCAAGAGGGGCAAATGGTGATCGAATATCGTGGGGACCAAGTCAGACGTAGTGTTGCTGATTTGAGGGAAGCACGATATCACAAGGAAAATAAAGACTGCTACCTGTTCAAAATAAGTGAAGATGTTGTGATTGATGCTACGGAGAGAGGAAACATCGCCCGCATAATTAACCACTCGTGCATGCCTAACTGCTACGCGAGGATCGTGAGCGTCGGCGACAACAAGAGCCAGATAATTCTGATTGCCAGAAGAGATGTCTCAGCCGGAGAAGAATTGACGTATGACTACAAATTTGACCCGGACGAGTCGGAGGATCGCAAGGTTCCCTGCCTGTGTAAAGCCCCTAACTGCCGTGGATACATGAACTGA
Protein Sequence
- >TraesCS3A01G143300
MLASRIPPKRCTAAVPYELEPPAAAAEGMPPAKRRRERVLPSRFRDSAVLLPPPAKKACKAPAPPKVEDRDGQVYEVEVRAVGPKGSAFGAVQTEVWTGEPAQTEEELYRACRNISRSGSSGCFSGSVVTSVSNAGEKCAPEKTPVVGAVVPSTSNAGTGNVGLEGRSPVVECKPKQEAEVRREDFYWPEDFVLGDVVWARSGKKSPAWPALVINPLQHAPEVVLNSCVPGALCVMFFGYSAGGQNRDYGWVKQGMIFPFVEYLDRFQGQSLHKLKLKPSKFRAAIEEAFLAERGFFELQMDGVCSLDKSVNEQSVTDGAREVTGSNNEQECQSHSQVVVKLAACCDSCGNRLPSKISKKKKQETEQLLCRHCEKLLQSKQYCGICKKIWHHTDGGNWVCCDECQIWVHVECDRTCSDLEDLENTEYFCPDCKSKRKRVMKVEQTSTSNSSDTSKEKLPESIPVCCSGMEALYLPEKHMILCECRSCKKKMMTLNEWERHTGSRKKNWKMSIKLKGTGEPLIDLLHDIPGGNFKSSTPGIKKEELLSLQANSYSPVYAKWTTERCAVCRWVEDWDYNKIIICNRCQIAVHQECYGARVVQDLTNWVCRACELPQQKKECCLCPVKGGALKPTDIDQLWVHVMCAWYQPKVSFPVDETMEPAVGILSIPSEYFKKTCIICKQMHGACTQCYKCSTYYHATCASRAGYRMELQYSERNGRKVTKMVSYCAFHSTPDPDNVLIVKTPDGVFSTKFLLQNNEKQSPARLAKSENHQEVFPAEVSDCPAARCLPYEILKNKKQQGEAVAHRIMGPRHHSQDLIEALNTYMDQKGDRPFATFKERLQYLQRTENKRVSCGRSGVHGWGLFAVRKIQEGQMVIEYRGDQVRRSVADLREARYHKENKDCYLFKISEDVVIDATERGNIARIINHSCMPNCYARIVSVGDNKSQIILIARRDVSAGEELTYDYKFDPDESEDRKVPCLCKAPNCRGYMN