Gene Details:

Functional Descriptions:

  • Pm5e encodes a nucleotide-binding domain leucine-rich-repeat-containing (NLR) protein.
  • A rare single nucleotide variant in Pm5e confers powdery mildew resistance in common wheat.
  • Results suggest that the NLR gene is sufficient to provide powdery mildew resistance and is the functional Pm5e allele.
  • The natural c.G3033A variant confers powdery mildew resistance of Pm5e.
  • Pm5e functions powdery mildew resistance through induced cell death.
  • The rare c.G3033A SNV detected in Pm5e by allelic association analysis of a diversified wheat panel proved to be the key causal variant responsible for powdery mildew resistance.

Literature:

Gene Resources:

Sequences:

cDNA Sequence
  • >TraesCS7B02G441700.1
    AGGAGGGGCGGTTCCGTGGGGCGGAGGCTTGGCCGGTTCTTCCAGTCACAGGTCAGGTCTTCTAAGCACCCTCCCCTTCCCCATGTTCCATGTACGTATAGGGGGCTGTTGAGTTGTGGTGTTCCACTTTGTCCACGCACTACTTTTTCGCCCATCTGATAGCTTCGTCCAAATCGAGATTTCCCTGGTGAAGATGGCGCAGATGGAGGATGTAGATGCCGCGTCCCCTCTGCCAGCGATGGCGTTGGACCCTGATCTCCACGCAGCGATTCGAGCTCCTGTTACTGTTATGCTGGGTCCGTCGGCCCTCCTCCTCCGGGAACTCGATTCTTCCGGACAGAGTCTTCTCGGTGCGGAGGAGCTTCGTCTTCTTAGAGATGCTCTCAGGGAAGTATGCATCCCCCTGAAGAGTATGTCCGAAGACGACGGTGCTAGCTTTATGGCCCGGTGGTGGATGAAGATAGTTCGGGAGCTTTGTTATGATACGCAGGATTACCTCAACTTCGTCCAAAGTGCTCGAGATCGTCCTGAATTTTCAGAGTTACCTGATCGTGCCAAGGCTGTTTATTCAGGCTTACTTGCTCGCGCCATTGATGCGAGGGAAAGACGCAGAGGTTTCAAGTGGTCTCCCAAGACCACCCGGTCTGACACGTGGGAAGCCTTCAACCGCCGCTTCTCCAAAAAACTTGTCCAGCTGCTGGGTTCCTTCGGTGTCCATACCACACCCGGTGCCGTGGTCGTGGAGGCCCCAAACAAGCTTGTCCAGCTGCTAGCTTTAGATGATGATGTCAACGACAAGACACTCAAGGTGATACCTATAATTGGATGTGCAGGTGTTGGAAAGACAACAGCTGCCAGAACCTTGTATCACAAGCATGGAGGGAAATTTCAGTGCCGGGCTTTTGTAAGTGTGTCTCAGAATCCAGATATGAGGGGAATCCTCACCAGCATGCTAGCACAACTTAAGGCACCACGGCCCCCTGGCTTTCCTGATGTGCTGGACCTTATTGGCGCTATCAGCAGGCATCTCCAAGGCAAAGGGTACTTGATCGTACTTGATGATTTATGGACTGCATCGGTATGGCATATTGTTAGCCGCGCTTTTCCTCGTGGTGATCACCGCAGCAGAATAATAACAACTACACAAGTGCATGACGTAGCATTGGCATGCTCTGGTTATCACCCGGTCCGTATATATAAGATGGAACTTCTTGATGAATATGAATCTCGAAAGTTATTCTTCCGTAGGGTGTTTAGCTCTGCCCCTGGAGATGGTTGTTCTCCAGCTACCAAAGAAGTCTCATACGAGATTATCAGAAAATGTGAAGGTTTGCCGTTAGCAATTGTAAGTATAGCAGGTCTGTTAGCAAGCGAATTAAGCATCGTCATGGAAGATTGGAGGCACATACAAAATTCTTTTTCCTCCACTTCCGAAGGGATGAAAGATATTTTAAACCTTATCTACAATAGTCTTCCACCTGGTTTGAGGACATGCTTGCTATATCTGAGTATGTATCCACAGGGCTACGTGATGAAGAAGGCTGAGTTGGTGAAGCACTGGGTAGCCGAAGGTTTTATCGGTGTTGTGGAAGGGACAGTCGCAATGAAAATTGCTGAGCGTTATTTTGATGAGCTTGTCAGCAGAGCAATGGTCCAGGCCGTGGACACCGATTATACTGGCAAGGTGTTGTCATGTACGGTTCACCATTTGGTACTGGATTTTATTAGGTCCAAATCTTTGGATGAGAATTTTGTCACCACTGTGGACTATTCTGAATCAACTCTAGCACACCCTGACAAAGTTCGTCGGTTATCCATCCAGTTTGGAGGGGTAAAAAGCGCATACATTCCAGAAACCATCGTAACATCGAAAGTTCGGTCACTTGTATTTTGGGGTTTCTTCAAGTGTGCGCCTCCTTCCATTATGGATTATGGATTTCTTCGTATTCTGAATCTTCATATTTGGGCTGATGAAGACAATGAGATTTTTGACCTCATTGGAATTGGGAACTTATTTCTTCTGAAGTATCTCACGGTTGAATGTAATATCACCGTCAAACTTCCAGAGAAGATTGGAATGCTCCGATACTTGGAGACACTGGAAGTAGATGCAAGATTGTTTGCTGTTCCATCAGATATGGATAATCTGGAGAGGTTACTGCACCTCCGTCTTCCGAGCGAATCTATCCTGCCTCAAGGAGTAGCCCACATGACATCTCTTCGCACTTTGGGGAATTTTGATCTCAGCCGCCGTTACTCAATAGAGAATGTATTACAACTTGGAGGGCTGTCTAATCTCCAGGATCTCCAGCTCACCTGTGCTATGGCACAGCAAGCAGAAAACCTGGAAAAGAATGTGCTACTCCTTGGCTGGATTGTTGAGAGGCTTAGTTTCTTGCAGACCATAACTTTGGTACCTGCTTCAGTGTCCTCTCATCAGGATGATGGTCAGGCTGCAGCACCTACAAGCATAATTATTCCCCCTGATGGATTTAACATGGAGCCTCCTCCAGACCTGCTTCTACAGAGGATCGAAATGTCGCGGCACTGCTGCATCTTCTTCTGCATACCTAAGTGCTTTGGAGAGCTAAGGAAACTCTGCATCCTAAAGATTGCAATTAGGAGTCTGTCGAGGAGTGATATTGAAATCCTGGAAAGAATGCCGGCCCTCGCTGCTCTCGCCCTGTATAATCAGACAACTCCCACAGAAAAGATGATCATGACTGACGGGGGATTCTATAGACTCACGTACTTCAAGTTCTTGTGTGCTGCACCATGCCTGTCCTTTGAACAAGGAGCGATGCCCAAACTCCAAAACCTCAACCTAGGATTCAACTCAGACCAATGGAGATCGGATACCTTTGAAACTCTTGGCTTGAGTCACTTGAGAGGCCTTACGGATGTATGTGTAAGACTTGGTACTGGGGCTGCTGACAACTTCAACGTAAAAGTTGCCGAGTCGGCATTGGAGGCTGTCGTCAGGAATCACCCCAACTCTCCTAGGATCAGAATAAAATTTGTGGATCTGATTTTTGATGGTAAGGAGGATGATAGCACCGCAACTCACCAGTATCAAGAAGGCAAGGAAAGCAGGTCTGCCAGAGGCCAAGATGGCAAACAAGATGCAACAAGGGGCGAACGTCAACAACAGGGGCCACCAATGAGCAAACAAGATGCACGGAGGAGCAAAGCAGTGGGAGCGTCATCAAAGGCACTACCACCGATGAGCAAAGCTGTAAATGCTAGCAAGTCAAGGGCAGCAGTACCTCCTCCCACCAGCTCTAGCCCATCAAAGCCGATGCCATCTTCCTCCCTTACCAGTCCACCAAAACCGAGGCGACGTGGCTCCCGCACCAGCCCTCCCCGACCCACGAGCCCGCCCCAACCCAAGCGCTAAGCTTTTGGCCAGGGGTTGAGCGCATCATCCCGCTTATTAGCGCCAGGGACATCCGACAGACAGACGGACGATGCACCAAGCGGTGAACCATGCGGCGGGAAGAACGAGCATCCGAGGAGCAGTCCCCACCCTGATGCCATCCAAACTGATCAGCTCTCTAAATATTACAGCATCTATTCTACATCCGTATGTACACATGTCTGCTTTTCTTGTGCACTAAGTTCTGTACTGTGTTTTCTTATAGGCTGGCACTTTTCAAAAAAAATTCAAAATGAGGATGTACCCCTCAGCCTCTGAGTGATGCACACAGCCTTATAGGCTGGCATTAT
CDS Sequence
  • >TraesCS7B02G441700.1
    ATGGCGCAGATGGAGGATGTAGATGCCGCGTCCCCTCTGCCAGCGATGGCGTTGGACCCTGATCTCCACGCAGCGATTCGAGCTCCTGTTACTGTTATGCTGGGTCCGTCGGCCCTCCTCCTCCGGGAACTCGATTCTTCCGGACAGAGTCTTCTCGGTGCGGAGGAGCTTCGTCTTCTTAGAGATGCTCTCAGGGAAGTATGCATCCCCCTGAAGAGTATGTCCGAAGACGACGGTGCTAGCTTTATGGCCCGGTGGTGGATGAAGATAGTTCGGGAGCTTTGTTATGATACGCAGGATTACCTCAACTTCGTCCAAAGTGCTCGAGATCGTCCTGAATTTTCAGAGTTACCTGATCGTGCCAAGGCTGTTTATTCAGGCTTACTTGCTCGCGCCATTGATGCGAGGGAAAGACGCAGAGGTTTCAAGTGGTCTCCCAAGACCACCCGGTCTGACACGTGGGAAGCCTTCAACCGCCGCTTCTCCAAAAAACTTGTCCAGCTGCTGGGTTCCTTCGGTGTCCATACCACACCCGGTGCCGTGGTCGTGGAGGCCCCAAACAAGCTTGTCCAGCTGCTAGCTTTAGATGATGATGTCAACGACAAGACACTCAAGGTGATACCTATAATTGGATGTGCAGGTGTTGGAAAGACAACAGCTGCCAGAACCTTGTATCACAAGCATGGAGGGAAATTTCAGTGCCGGGCTTTTGTAAGTGTGTCTCAGAATCCAGATATGAGGGGAATCCTCACCAGCATGCTAGCACAACTTAAGGCACCACGGCCCCCTGGCTTTCCTGATGTGCTGGACCTTATTGGCGCTATCAGCAGGCATCTCCAAGGCAAAGGGTACTTGATCGTACTTGATGATTTATGGACTGCATCGGTATGGCATATTGTTAGCCGCGCTTTTCCTCGTGGTGATCACCGCAGCAGAATAATAACAACTACACAAGTGCATGACGTAGCATTGGCATGCTCTGGTTATCACCCGGTCCGTATATATAAGATGGAACTTCTTGATGAATATGAATCTCGAAAGTTATTCTTCCGTAGGGTGTTTAGCTCTGCCCCTGGAGATGGTTGTTCTCCAGCTACCAAAGAAGTCTCATACGAGATTATCAGAAAATGTGAAGGTTTGCCGTTAGCAATTGTAAGTATAGCAGGTCTGTTAGCAAGCGAATTAAGCATCGTCATGGAAGATTGGAGGCACATACAAAATTCTTTTTCCTCCACTTCCGAAGGGATGAAAGATATTTTAAACCTTATCTACAATAGTCTTCCACCTGGTTTGAGGACATGCTTGCTATATCTGAGTATGTATCCACAGGGCTACGTGATGAAGAAGGCTGAGTTGGTGAAGCACTGGGTAGCCGAAGGTTTTATCGGTGTTGTGGAAGGGACAGTCGCAATGAAAATTGCTGAGCGTTATTTTGATGAGCTTGTCAGCAGAGCAATGGTCCAGGCCGTGGACACCGATTATACTGGCAAGGTGTTGTCATGTACGGTTCACCATTTGGTACTGGATTTTATTAGGTCCAAATCTTTGGATGAGAATTTTGTCACCACTGTGGACTATTCTGAATCAACTCTAGCACACCCTGACAAAGTTCGTCGGTTATCCATCCAGTTTGGAGGGGTAAAAAGCGCATACATTCCAGAAACCATCGTAACATCGAAAGTTCGGTCACTTGTATTTTGGGGTTTCTTCAAGTGTGCGCCTCCTTCCATTATGGATTATGGATTTCTTCGTATTCTGAATCTTCATATTTGGGCTGATGAAGACAATGAGATTTTTGACCTCATTGGAATTGGGAACTTATTTCTTCTGAAGTATCTCACGGTTGAATGTAATATCACCGTCAAACTTCCAGAGAAGATTGGAATGCTCCGATACTTGGAGACACTGGAAGTAGATGCAAGATTGTTTGCTGTTCCATCAGATATGGATAATCTGGAGAGGTTACTGCACCTCCGTCTTCCGAGCGAATCTATCCTGCCTCAAGGAGTAGCCCACATGACATCTCTTCGCACTTTGGGGAATTTTGATCTCAGCCGCCGTTACTCAATAGAGAATGTATTACAACTTGGAGGGCTGTCTAATCTCCAGGATCTCCAGCTCACCTGTGCTATGGCACAGCAAGCAGAAAACCTGGAAAAGAATGTGCTACTCCTTGGCTGGATTGTTGAGAGGCTTAGTTTCTTGCAGACCATAACTTTGGTACCTGCTTCAGTGTCCTCTCATCAGGATGATGGTCAGGCTGCAGCACCTACAAGCATAATTATTCCCCCTGATGGATTTAACATGGAGCCTCCTCCAGACCTGCTTCTACAGAGGATCGAAATGTCGCGGCACTGCTGCATCTTCTTCTGCATACCTAAGTGCTTTGGAGAGCTAAGGAAACTCTGCATCCTAAAGATTGCAATTAGGAGTCTGTCGAGGAGTGATATTGAAATCCTGGAAAGAATGCCGGCCCTCGCTGCTCTCGCCCTGTATAATCAGACAACTCCCACAGAAAAGATGATCATGACTGACGGGGGATTCTATAGACTCACGTACTTCAAGTTCTTGTGTGCTGCACCATGCCTGTCCTTTGAACAAGGAGCGATGCCCAAACTCCAAAACCTCAACCTAGGATTCAACTCAGACCAATGGAGATCGGATACCTTTGAAACTCTTGGCTTGAGTCACTTGAGAGGCCTTACGGATGTATGTGTAAGACTTGGTACTGGGGCTGCTGACAACTTCAACGTAAAAGTTGCCGAGTCGGCATTGGAGGCTGTCGTCAGGAATCACCCCAACTCTCCTAGGATCAGAATAAAATTTGTGGATCTGATTTTTGATGGTAAGGAGGATGATAGCACCGCAACTCACCAGTATCAAGAAGGCAAGGAAAGCAGGTCTGCCAGAGGCCAAGATGGCAAACAAGATGCAACAAGGGGCGAACGTCAACAACAGGGGCCACCAATGAGCAAACAAGATGCACGGAGGAGCAAAGCAGTGGGAGCGTCATCAAAGGCACTACCACCGATGAGCAAAGCTGTAAATGCTAGCAAGTCAAGGGCAGCAGTACCTCCTCCCACCAGCTCTAGCCCATCAAAGCCGATGCCATCTTCCTCCCTTACCAGTCCACCAAAACCGAGGCGACGTGGCTCCCGCACCAGCCCTCCCCGACCCACGAGCCCGCCCCAACCCAAGCGCTAA
Protein Sequence
  • >TraesCS7B02G441700.1
    MAQMEDVDAASPLPAMALDPDLHAAIRAPVTVMLGPSALLLRELDSSGQSLLGAEELRLLRDALREVCIPLKSMSEDDGASFMARWWMKIVRELCYDTQDYLNFVQSARDRPEFSELPDRAKAVYSGLLARAIDARERRRGFKWSPKTTRSDTWEAFNRRFSKKLVQLLGSFGVHTTPGAVVVEAPNKLVQLLALDDDVNDKTLKVIPIIGCAGVGKTTAARTLYHKHGGKFQCRAFVSVSQNPDMRGILTSMLAQLKAPRPPGFPDVLDLIGAISRHLQGKGYLIVLDDLWTASVWHIVSRAFPRGDHRSRIITTTQVHDVALACSGYHPVRIYKMELLDEYESRKLFFRRVFSSAPGDGCSPATKEVSYEIIRKCEGLPLAIVSIAGLLASELSIVMEDWRHIQNSFSSTSEGMKDILNLIYNSLPPGLRTCLLYLSMYPQGYVMKKAELVKHWVAEGFIGVVEGTVAMKIAERYFDELVSRAMVQAVDTDYTGKVLSCTVHHLVLDFIRSKSLDENFVTTVDYSESTLAHPDKVRRLSIQFGGVKSAYIPETIVTSKVRSLVFWGFFKCAPPSIMDYGFLRILNLHIWADEDNEIFDLIGIGNLFLLKYLTVECNITVKLPEKIGMLRYLETLEVDARLFAVPSDMDNLERLLHLRLPSESILPQGVAHMTSLRTLGNFDLSRRYSIENVLQLGGLSNLQDLQLTCAMAQQAENLEKNVLLLGWIVERLSFLQTITLVPASVSSHQDDGQAAAPTSIIIPPDGFNMEPPPDLLLQRIEMSRHCCIFFCIPKCFGELRKLCILKIAIRSLSRSDIEILERMPALAALALYNQTTPTEKMIMTDGGFYRLTYFKFLCAAPCLSFEQGAMPKLQNLNLGFNSDQWRSDTFETLGLSHLRGLTDVCVRLGTGAADNFNVKVAESALEAVVRNHPNSPRIRIKFVDLIFDGKEDDSTATHQYQEGKESRSARGQDGKQDATRGERQQQGPPMSKQDARRSKAVGASSKALPPMSKAVNASKSRAAVPPPTSSSPSKPMPSSSLTSPPKPRRRGSRTSPPRPTSPPQPKR