Gene Details:
- Gene ID:
- Gene Symbol: Pm36
- Gene Name: powdery mildew resistance 36
- Genome: Chinese_Spring1.0
- Species: Triticum aestivum
Functional Descriptions:
- The isolation of broad-spectrum powdery mildew resistance gene Pm36, originated from wild emmer wheat, that encodes a tandem kinase with a transmembrane domain (WTK7-TM) through the combination of map-based cloning, PacBio SMRT long-read genome sequencing, mutagenesis, and transformation.
- Haplotype analysis uncovers that Pm36 is an orphan gene only present in a few wild emmer wheat, indicating its single ancient origin and potential contribution to the current wheat gene pool.
- Pm36, a wild emmer wheat (WEW)-derived powdery mildew resistance gene, was identified and mapped on chromosome arm 5BL in the tetraploid WEW-durum introgression line 5BIL-29.
- Pm36 encodes a unique tandem kinase with a transmembrane domain in the C-terminus (WTK7-TM).
- Pm36 is only present in a few WEW populations with a single ancient origin and can potentially contribute to modern wheat improvement.
Function-related keywords:
- kinase , resistance , map-based-cloning , powdery-mildew , mildew-resistance , mildew , powdery-mildew-resistance
Literature:
- A membrane associated tandem kinase from wild emmer wheat confers broad-spectrum resistance to powdery mildew. DOI: 10.1038/s41467-024-47497-w ; PMID: 38600164
Related News:
Gene Resources:
- NCBI ID: OQ361691.1
- UniProt accessions: A0A3B6THV6
Orthologs:
Sequences:
cDNA Sequence
- >OQ361691
ATGGAGTACAAGTCACAGCATACAAGTGCGACACCGACGGGTCTTACATTCAAATTGTTAGAACATGCTACAAATAATTTTTCCGATGATCACATAATTGGTTCCGGCTCATATGGAGTAGTTTACAAGGTATCATCTTTACTTAATTACTTACCGCTTTGCTTTCTCAAATGATACCGTGGCAAACTACAAGAATTATAGAGCTGCAACTGCAACCTGGAGTAACAATGCCATACAACCATGCGCTAAGTATATGGACGCACACATTTTTTGAACAGACATGGAACCACTAATTATATAAAAAATGTTTTTTTAACAGGGAATATTGGGAGATGGGCAAGAGATAGCTGTGAAGAAACTTTATCCCCAACTGTTCGATGGTGTGAGATTACAACAACAATATAATGAACTCATAGATATCAACCATGAAAATATTGTACGGTTAGTTAGCTGCTGCCAAGAGACACGATATAAGCATATTGAGCACAAGGGAGAGCTTGTTTTCGCCAAGCTGCAGGAAATTGCTCTTTGCTCGGAATACTTGCCAGGTGGAAGCCTTGACAAGCATGTTTCTGGTACGATGGTGCTTTGTTAGACTATTGTTGGTATTTTCAATTTTCTTTAGACCATTACTTTGCATTTAAAGGAAAGAAAGGTCCCCAAATATGCATCTTGGTAATATATTTCTCGTTACTTCTACAGACGAATCCCGTGGACTTCATTGGCACACACGTTACAAAATTATTAAGGGAATCTGCGAGGGCTTAAATCACCTTCATAGTAGCCGCGGTAAACCAATTTACCATATGAACCTAAAAATTACAAATATATTATTGGATAGGAACATGGTACCAAAAATCGGGGACCTTGAGACGTCAAGGATGCGCATGCAGTTAGAAGACTATGATGGAGACCATACTATGGGAACAATGTAAGGTTATATTCCTTTATAAGGACTTACCAACCTCTTTCGTTATTTTGTATAAAGTAATTGTATTTGATACCATGCAGGCGGTACCTGCCACCGGAATACATAGATAGCGGCTCCATTTCAAAGAAGATGGACGTATTCAGTTTGGGGATCATAATCATACAAATAATGGCAGGAGACGATGCTGTTGAAAAACGTGCAGAGATGCCTCCACAAGAATTTATTGAGCTTGTAAGAAATATAATCATATACCATGAGTGTTCCTTTTTTGCAAAAAATATATATTGTGTCTTAACGGGAAGCATGGAATGAAGGTACACGAGAATTGGCGAAAAAGGTTCCAGACAACGATGTTGTTTCCTAGTGCATCACATGAAGTCAGGACATGTATCAGAATAGCATTGATGTGTGTTGAACGCGATCGAAACAAAAGACCTACCATAAGCAACATTGTGCATGAATTGAATAAGATAGATACTTCGCCTATGAGCCAAGTACATAGGACAAGGGAGTTTACGTTCGAGTTGTTAAACCATATTACAAATCATTTTTCCAGTGAGTGTGAACTTGGTCGTGGTGGGTTTGGAGTAGTTTACAAGGTATGACCGGTTCATAGTTGCCTTCTCACTCTTGCAAATGATACTGAACGGCAACAACAGAAATGCTTAGGCATACCAATAATAATATAAGTTCATACCAGAGTAACATAGTTTTTTTAACAGGGAATACTTGATGATGGGGAAGAGATTGCTGTGAAGAAGCTTAAAAGCATGCCGCTGCTTGATGACCATCAATTTAATAATGAGTTAAACAATCTTAAGACACTTGAGCATCCAAATATTGTACGGTTAGTTGGCTACTGCCATGATACGACACTAGTAAATGTTGAGCACAATGGAAGAGTGGTTTGTGCTGCTGTGGAGGAAAGAGCTTTATGCTACGAATACTTGGAGGAAGGAAGCCTTGACAAGTATCTTTCCGGTATTGTTATGCTCTATGCAGAAAATATTTCTTTGCATGTGACGATAAAATGTCCCTAAACTTTATGTCCTGGTAATGCGGTTTGTGTTTACTTTTACAGATGAATCATGTGGATTTGATTGGCATGTACGTTACAAAATAATTAGGGGGATTAGTGCAGGTCTACATTACCTTCAAAACGGATCCAAGCATCCCATTTACCATCTGGACTTAAAACCTGCAAACATATTATTGGACAAAGACATGATGCCAAAGATAGGAGATTTTGGTTTGTCGAGGCTCTTTGATTTGATACAAACATATCTCACACAATCCCAAAACTCTCCGGGAACACCGTGAGTTTATATTCCTATAAGTTATTAACTTATTTTATGATTTTATTTTGAAAATAAGTGCATTTGATATGATGCAGTGGATATATGCCACCGGAGTACATCGATGAACATCAAATATCACCAAAATTTGACATATTCAGTTTCGGTGTTATAATCATACAAATAATGATAGGGAAGAATGGTCGCTACAGTTATGCAACCATGGCTCCCAAGGAATTTATTAAACTTGTAAGTAAAACAACTTTCATAAGAAACAGTCATTTCCATAAATGCTATTATGTGCCTTAGTTATCCTCTCTGCATGCACGCCACTTTTCAACATTGGTTATTCTTCAATTATGCAGGTACAGGAAAAGTGGAAAAAAAGGATGCCGGAAGCAATGTGGCCTCATACATCAGAGGAAGTGAAGACGTGTATCGAATTAGCATTAAGATGTGTCGACACCAACCGTGAGAAAAGGCCTAGCATCACTGAGATTATAGATGAACTGAATAATATTGGTACTGCCAAAAGTACACCGAAAATCCAGGTATGTCAGTTGTCAGGGTACTGCTCACTTTTACCTGCCTATTGTAGTACAAGGTGTGAATTTCCTCGTCCTATGTAGACTTGTATGGAATGTTTAAACTAGCTTCCCTGCCAAATATTTTCTCAAAACAAAACATGAGCATATAACTATTTGGGGCACTTAGTAAACTTCTATGCTACGATCTTGATTGACCAGAAAAGAAGCCAGCCATATTCCCTTGTTGTGGATATATATCCGCAAATCTTAAATTTGTGAAACTTTAAAATACGGTTTTCATCTGAATGTAGTGGCCAAACAAGCTGATGGACCCGAAGACCTCAATATTATCTGAAAACTTCAAAGATTGGTTGTTTCTCTTATTGGCAATAATAATCATGTATTCATCGTGGCCGCTGCTCCTGTCCAGGTATTGCACAGTTGACAGATTACCTCTATAATTGAGTTACATATCGCCTCAATTGTCTAAGTTATCCAATTATGAAAAATCATGGTGCAGATAA
CDS Sequence
- >OQ361691
ATGGAGTACAAGTCACAGCATACAAGTGCGACACCGACGGGTCTTACATTCAAATTGTTAGAACATGCTACAAATAATTTTTCCGATGATCACATAATTGGTTCCGGCTCATATGGAGTAGTTTACAAGGGAATATTGGGAGATGGGCAAGAGATAGCTGTGAAGAAACTTTATCCCCAACTGTTCGATGGTGTGAGATTACAACAACAATATAATGAACTCATAGATATCAACCATGAAAATATTGTACGGTTAGTTAGCTGCTGCCAAGAGACACGATATAAGCATATTGAGCACAAGGGAGAGCTTGTTTTCGCCAAGCTGCAGGAAATTGCTCTTTGCTCGGAATACTTGCCAGGTGGAAGCCTTGACAAGCATGTTTCTGACGAATCCCGTGGACTTCATTGGCACACACGTTACAAAATTATTAAGGGAATCTGCGAGGGCTTAAATCACCTTCATAGTAGCCGCGGTAAACCAATTTACCATATGAACCTAAAAATTACAAATATATTATTGGATAGGAACATGGTACCAAAAATCGGGGACCTTGAGACGTCAAGGATGCGCATGCAGTTAGAAGACTATGATGGAGACCATACTATGGGAACAATGCGGTACCTGCCACCGGAATACATAGATAGCGGCTCCATTTCAAAGAAGATGGACGTATTCAGTTTGGGGATCATAATCATACAAATAATGGCAGGAGACGATGCTGTTGAAAAACGTGCAGAGATGCCTCCACAAGAATTTATTGAGCTTGTACACGAGAATTGGCGAAAAAGGTTCCAGACAACGATGTTGTTTCCTAGTGCATCACATGAAGTCAGGACATGTATCAGAATAGCATTGATGTGTGTTGAACGCGATCGAAACAAAAGACCTACCATAAGCAACATTGTGCATGAATTGAATAAGATAGATACTTCGCCTATGAGCCAAGTACATAGGACAAGGGAGTTTACGTTCGAGTTGTTAAACCATATTACAAATCATTTTTCCAGTGAGTGTGAACTTGGTCGTGGTGGGTTTGGAGTAGTTTACAAGGGAATACTTGATGATGGGGAAGAGATTGCTGTGAAGAAGCTTAAAAGCATGCCGCTGCTTGATGACCATCAATTTAATAATGAGTTAAACAATCTTAAGACACTTGAGCATCCAAATATTGTACGGTTAGTTGGCTACTGCCATGATACGACACTAGTAAATGTTGAGCACAATGGAAGAGTGGTTTGTGCTGCTGTGGAGGAAAGAGCTTTATGCTACGAATACTTGGAGGAAGGAAGCCTTGACAAGTATCTTTCCGATGAATCATGTGGATTTGATTGGCATGTACGTTACAAAATAATTAGGGGGATTAGTGCAGGTCTACATTACCTTCAAAACGGATCCAAGCATCCCATTTACCATCTGGACTTAAAACCTGCAAACATATTATTGGACAAAGACATGATGCCAAAGATAGGAGATTTTGGTTTGTCGAGGCTCTTTGATTTGATACAAACATATCTCACACAATCCCAAAACTCTCCGGGAACACCTGGATATATGCCACCGGAGTACATCGATGAACATCAAATATCACCAAAATTTGACATATTCAGTTTCGGTGTTATAATCATACAAATAATGATAGGGAAGAATGGTCGCTACAGTTATGCAACCATGGCTCCCAAGGAATTTATTAAACTTGTACAGGAAAAGTGGAAAAAAAGGATGCCGGAAGCAATGTGGCCTCATACATCAGAGGAAGTGAAGACGTGTATCGAATTAGCATTAAGATGTGTCGACACCAACCGTGAGAAAAGGCCTAGCATCACTGAGATTATAGATGAACTGAATAATATTGGTACTGCCAAAAGTACACCGAAAATCCAGTGGCCAAACAAGCTGATGGACCCGAAGACCTCAATATTATCTGAAAACTTCAAAGATTGGTTGTTTCTCTTATTGGCAATAATAATCATGTATTCATCGTGGCCGCTGCTCCTGTCCAGATAA
Protein Sequence
- >OQ361691
MEYKSQHTSATPTGLTFKLLEHATNNFSDDHIIGSGSYGVVYKGILGDGQEIAVKKLYPQLFDGVRLQQQYNELIDINHENIVRLVSCCQETRYKHIEHKGELVFAKLQEIALCSEYLPGGSLDKHVSDESRGLHWHTRYKIIKGICEGLNHLHSSRGKPIYHMNLKITNILLDRNMVPKIGDLETSRMRMQLEDYDGDHTMGTMRYLPPEYIDSGSISKKMDVFSLGIIIIQIMAGDDAVEKRAEMPPQEFIELVHENWRKRFQTTMLFPSASHEVRTCIRIALMCVERDRNKRPTISNIVHELNKIDTSPMSQVHRTREFTFELLNHITNHFSSECELGRGGFGVVYKGILDDGEEIAVKKLKSMPLLDDHQFNNELNNLKTLEHPNIVRLVGYCHDTTLVNVEHNGRVVCAAVEERALCYEYLEEGSLDKYLSDESCGFDWHVRYKIIRGISAGLHYLQNGSKHPIYHLDLKPANILLDKDMMPKIGDFGLSRLFDLIQTYLTQSQNSPGTPGYMPPEYIDEHQISPKFDIFSFGVIIIQIMIGKNGRYSYATMAPKEFIKLVQEKWKKRMPEAMWPHTSEEVKTCIELALRCVDTNREKRPSITEIIDELNNIGTAKSTPKIQWPNKLMDPKTSILSENFKDWLFLLLAIIIMYSSWPLLLSR