Gene Details:

Functional Descriptions:

  • We examined the impact of silencing and ectopic expression of Mds-1 in susceptible and resistant wheat genotypes.
  • Silencing of Mds-1 inhibits Hessian fly development.
  • Mds-1 confers resistance gene plants susceptibility.
  • Here we show that the gene Mayetiola destructor susceptibility-1 on wheat chromosome 3AS encodes a small heat-shock protein and is a major susceptibility gene for infestation of wheat by the gall midge M. destructor, commonly known as the Hessian fly.
  • Silencing of Mayetiola destructor susceptibility-1 by RNA interference confers immunity to all Hessian fly biotypes on normally susceptible wheat genotypes. Mayetiola destructor susceptibility-1-silenced plants also show reduced lesion formation due to infection by the powdery mildew fungus Blumeria graminis f. sp. tritici.

Literature:

Gene Resources:

Sequences:

cDNA Sequence
  • >TraesCSU02G074100LC
    TCAGCCGGAGATCTCGATGGCCTTCACCTCGGGCTTCTTGACCTCGGCCTTGGGCACGGTGACGGTGAGCACGCCGTTCTCCAGCCCGGCCTTGACCTCCTCCACCTTGGCGTCCTCCGGCAGCCGGAAACGCCGCACGAACTTGCCGCTGCTGCGCTCCACGCGGTGCCACTTGTCGTTCTTGTCCTCCTTCTCCCTGCTCCGCTCGCCGCTGACGACGAGCACGTTGCCGTCCTCCACCTCCACCTTGACCTCCTCCTTCTTCACGCCGGGGAGGTCGACCTTGAAGACGTGCGCCTCGGGGGTCTCCTTCCAGTCCACACGGGCGTTGGCGAACGCGGCCGTCTCGCTGCTGCCGCCTGAGATCGCCGGGACGATGGAACGGAAGGTGTCGAAGGGGTCCGCCCAAAGGTCGGCGAAGGGGTCGAACACGTTGCTCCGCCTCACGATCGACAT
CDS Sequence
  • >TraesCSU02G074100LC
    ATGTCGATCGTGAGGCGGAGCAACGTGTTCGACCCCTTCGCCGACCTTTGGGCGGACCCCTTCGACACCTTCCGTTCCATCGTCCCGGCGATCTCAGGCGGCAGCAGCGAGACGGCCGCGTTCGCCAACGCCCGTGTGGACTGGAAGGAGACCCCCGAGGCGCACGTCTTCAAGGTCGACCTCCCCGGCGTGAAGAAGGAGGAGGTCAAGGTGGAGGTGGAGGACGGCAACGTGCTCGTCGTCAGCGGCGAGCGGAGCAGGGAGAAGGAGGACAAGAACGACAAGTGGCACCGCGTGGAGCGCAGCAGCGGCAAGTTCGTGCGGCGTTTCCGGCTGCCGGAGGACGCCAAGGTGGAGGAGGTCAAGGCCGGGCTGGAGAACGGCGTGCTCACCGTCACCGTGCCCAAGGCCGAGGTCAAGAAGCCCGAGGTGAAGGCCATCGAGATCTCCGGCTGA
Protein Sequence
  • >TraesCSU02G074100LC
    MSIVRRSNVFDPFADLWADPFDTFRSIVPAISGGSSETAAFANARVDWKETPEAHVFKVDLPGVKKEEVKVEVEDGNVLVVSGERSREKEDKNDKWHRVERSSGKFVRRFRLPEDAKVEEVKAGLENGVLTVTVPKAEVKKPEVKAIEISG