Gene Details:

Functional Descriptions:

  • DES1 is an ortholog of Sr35, which recognizes a Puccinia graminis f. sp. tritici stem rust disease effector in wheat.
  • The overexpression of mDES1 triggered necrosis and PCD in transgenic plants.
  • Abnormal cell division and effects of hormones on mDES1 plants.
  • DES1 is an ortholog of Sr35, which recognizes a Puccinia graminis f. sp. tritici stem rust disease effector in wheat, but mDES1 gained function as a direct inducer of plant death.
  • The point mutation in mDES1 did not cause changes in this protein in the oligomeric state, but mDES1 failed to interact with replication protein A leading to abnormal mitotic cell division.

Literature:

Gene Resources:

Sequences:

cDNA Sequence
  • >TraesCS3D02G474300.1
    AGAGCTTCCATATATTGAAGGAAACAAACATTGCCCAGAGTGTCTTCGTACCAATCGCAAGCTCTTCCACCTCTCTTCCACCTAAACCACTACCACAACCTCTTGTAGAGAGGGCAAGACATGGAGATTGCCATGGGGGCTATCGGCCCTCTCCTCCCGAAGCTCGCCGAGCTGCTCGTCGGCGAGCTCACCATGGAGAAACAAGTGAGGAAAGGCATCGTGTCTCTCGTAACAGAGCTGAAATTGATGCATGTTGTCCTTAGCAAGGTGTCAAAAGTGCCTGCGGACCAGCTTGACGAGGGGGTCAAGATCTGGGCAGGAAATGTCAAGGAGTTGTCCTACCAAATGGAGGACATCGTTGATGCTTTCATGGTGCGTGTGGGGAATGATGGCGAGTCCACCAACCCGAGGAACAGAGTCAAGAAGATACTCAAGAAGGTCAAAAGATTATTCAAGAATGGCAAGGATCTCCATCGGATCTCTGATGCTCTAGATGAAGTGGTTCTTCAAGCTAAGCAGTTGGCCGAGCTGCGTCAAAGGTACGAGCAAGAGATGCGGGACACTAGTGCTCATACTAGTGTTGACCCTCGCATGATGGCCTTGTACACAGATGTGACAGAGCTCGTCGGCATTGAAGAAACACGAGACAAGTTGATCAACATGTTGATTGAAGATGATGATTGGTCGAAGTATCCGTTGAAGACGATCTCTATTGTTGGATTTGGTGGGTTAGGCAAGACAACTCTTGCCAAAGCAGCATACGACAAGATCAAAGTGCAATTTGATTGTGGTGCTTTTGTCTCGGTTTCGCAAAACCCTGAAATGAAAAAGGTTTTGAAGGATATTCTCTATGGACTTGACAAGGTCAAGTACGAAAACATACACAATGCAGCGAGGGACGAAAAGTATCTCATTGAAGATATAATTGAATTCCTTAATGAAAAGAGGTACCTCATCGTAGTCGATGATATATGGAATGAAAAAGCATGGGAGTTAATTAAGTGTGCTTTCTCCAAGAAGAGCCCCGGAAGCCGACTAATCACGACAACCCGCAATGTTAGTGTCTCTACAGCATGTTGCTCTTTTGAGGGTGATATTTATAGAATGGAACCCCTTTCTGATGATGTATCAAGAAGACTCTTCTGTAAAAGAGTCTTTTCACAAGAAGAAGGCTGCCCTCGAGAATTGTTGCAAGTATCCGAAGAAATTTTGAAGAAATGTGGTGGTATACCGTTAGCTATTATTACTATAGCAAGTCTTCTAGCTAATAAGGGTCAGATAAAAGCAAAGGATGAATGGTATGCTTTGCTCAGTTCCATTGGTCATGGACTCACAGAAGATCGCAGTTTGGAGCAGATGAAAAAGATATTATTATTCAGCTACTATGATCTACCTTCATATCTAAAACCTTGTCTATTATATCTTAGCATCTTCCCAGAAGATCATGCGATTGTGAGAGGTAGACTGATATGGAGATGGATATCCGAAGGTCTTGTTTACAGTGATAAACAAGAAACTAGCTTATATGAGCTCGGTAATAGTTACTTCACTGAGCTAGTAAATAGAAGTATGGTCCAGCCAATAGGCATTGATGTTGAAGGAAATGTAGAAGGTTGCCGTGTACATGACATGGTGCTTGACCTTATATGCTCATTATCAAGTGAAGAAAACTTTGTCACAATACTAGATGACACCAGAAGAAAAATACCTAACTCAGAGATCAAGGTTCGCAGATTGTCCATTCAAAATACCAAGATAGATGTGGATACCACTAGGATGGAACATATGAGATCTCTTACCATTTTCACAAGTGATGTTGTTGGGAAAGTGTTGGATATTTCAAGTTTTCAAGTTCTGCGCGTGTTGGATTTAGAAGGTTGTAAAAATGTCTCAGATGTTGGGTATGTCGGGAATCTGTTACATTTGAGGTACTTGGGGCTAAAAGATACTCATGTTAAGGACCTTCCCATGGAAATAGGGAAGCTGCAGTTTTTGCTTACCTTGGACTTAAGAGGTTCTAATATAAAAGTACTGCCATCGAGTGTTGTTCAACTAAGACGTCTAATGTGCCTGTATGTTGATTATGATATGAAGCTGTCATCTGGGATAGGTAACCTGACATCCCTAGAAGTGCTAGATGACCTGGGGTTATCTGACGTGGACCTTGATTTTGTGAAAGAATTGGGCCGTCTGACCAAGCTCAGGGTGCTCCGGCTTGACTGCGATGATTTTGATGAGAGCCTGGGTAAAGCTTTGGAGGAATCCATTTGTAATATACACAAACTGGACAGTCTAGATGTATATGTCTCTGATGGACTCATCAATTGCCTGAGCGAAGATTGGGTGCCTCCTCCACAACTCCGTAGATTGGCTTTCCCGGCAATTCAAAGTTGGTTCGAGACATTGCCGTCATGGATTAATCCTTCATCCCTTCCTCTCCTCTCCTATCTGGAGATAACGTTGTTTGAAGTGCGACCGGAGGTCATCCAATTTCTAGGGACTCTACCTGCTCTTGTTTATCTCGAGATACTGGATCATTCTGTGTTCCAAGAAGCGCATGAGGTGGAAGCGCCCGTCCTTTCCTCTAATGTTGCATTATTCCCATGTGCGACAGAGTGCCGCTTCTATGGTATTGGTGCCGTGCCATCTATGTTTCCACGAGGAGCTGCGCCGAGGCTTAAACAGCTTAGGTTCGCTTTACCAGCGAAGTGGGTCTCCCGTGAAAACATTGATTTGGGCATGAGGCACCTTCCTTCCCTCCAGCGAGTCACTGTTACAGTTTCCCAAGGAGAAGCTAACGATCAGGAGGTGGATGAAGCAAAGGCTGCTGTGAGGGCCGCGGTGGAAGACCACCCCAACCGTCCCGTCCTCGAGATTTAATTGACCCATCACGCACGCATAGGAAAAAGGCAGAGGAAGCAAAGCATGCGTTGAGTTTCCTGGTGCGGAGTGCTAGGTCGATTTCTCAAAAATCTTGAAATCAGGTAGAATGAGCTAACAGATGTCGTCGACATGTACTCAATCGTGCGTGCCTCCAACTCCGGTGTCCCTTCTTTTCCAACCAATACAGTGAAGCACGCTGCATTTTCCTTGCTGTTTGATCCGCCTTCTTTCTCCAAGGAGAGATGAAGGCCCCATTATGGCCTGTCATGTTTGAGTTATCCTTTTCTTTATACCAATTCAAGAACAATCAAGCTTGTAGGGCACCCCCTGCATTTTGCCCTGATGAACCATTAGTTATTATGTACTGATGATGTATGGTTTGCCTCCTATCCAGCGTTGTTCATTACACTCCTTTATTTGTAACAGCTTTT
CDS Sequence
  • >TraesCS3D02G474300.1
    ATGGAGATTGCCATGGGGGCTATCGGCCCTCTCCTCCCGAAGCTCGCCGAGCTGCTCGTCGGCGAGCTCACCATGGAGAAACAAGTGAGGAAAGGCATCGTGTCTCTCGTAACAGAGCTGAAATTGATGCATGTTGTCCTTAGCAAGGTGTCAAAAGTGCCTGCGGACCAGCTTGACGAGGGGGTCAAGATCTGGGCAGGAAATGTCAAGGAGTTGTCCTACCAAATGGAGGACATCGTTGATGCTTTCATGGTGCGTGTGGGGAATGATGGCGAGTCCACCAACCCGAGGAACAGAGTCAAGAAGATACTCAAGAAGGTCAAAAGATTATTCAAGAATGGCAAGGATCTCCATCGGATCTCTGATGCTCTAGATGAAGTGGTTCTTCAAGCTAAGCAGTTGGCCGAGCTGCGTCAAAGGTACGAGCAAGAGATGCGGGACACTAGTGCTCATACTAGTGTTGACCCTCGCATGATGGCCTTGTACACAGATGTGACAGAGCTCGTCGGCATTGAAGAAACACGAGACAAGTTGATCAACATGTTGATTGAAGATGATGATTGGTCGAAGTATCCGTTGAAGACGATCTCTATTGTTGGATTTGGTGGGTTAGGCAAGACAACTCTTGCCAAAGCAGCATACGACAAGATCAAAGTGCAATTTGATTGTGGTGCTTTTGTCTCGGTTTCGCAAAACCCTGAAATGAAAAAGGTTTTGAAGGATATTCTCTATGGACTTGACAAGGTCAAGTACGAAAACATACACAATGCAGCGAGGGACGAAAAGTATCTCATTGAAGATATAATTGAATTCCTTAATGAAAAGAGGTACCTCATCGTAGTCGATGATATATGGAATGAAAAAGCATGGGAGTTAATTAAGTGTGCTTTCTCCAAGAAGAGCCCCGGAAGCCGACTAATCACGACAACCCGCAATGTTAGTGTCTCTACAGCATGTTGCTCTTTTGAGGGTGATATTTATAGAATGGAACCCCTTTCTGATGATGTATCAAGAAGACTCTTCTGTAAAAGAGTCTTTTCACAAGAAGAAGGCTGCCCTCGAGAATTGTTGCAAGTATCCGAAGAAATTTTGAAGAAATGTGGTGGTATACCGTTAGCTATTATTACTATAGCAAGTCTTCTAGCTAATAAGGGTCAGATAAAAGCAAAGGATGAATGGTATGCTTTGCTCAGTTCCATTGGTCATGGACTCACAGAAGATCGCAGTTTGGAGCAGATGAAAAAGATATTATTATTCAGCTACTATGATCTACCTTCATATCTAAAACCTTGTCTATTATATCTTAGCATCTTCCCAGAAGATCATGCGATTGTGAGAGGTAGACTGATATGGAGATGGATATCCGAAGGTCTTGTTTACAGTGATAAACAAGAAACTAGCTTATATGAGCTCGGTAATAGTTACTTCACTGAGCTAGTAAATAGAAGTATGGTCCAGCCAATAGGCATTGATGTTGAAGGAAATGTAGAAGGTTGCCGTGTACATGACATGGTGCTTGACCTTATATGCTCATTATCAAGTGAAGAAAACTTTGTCACAATACTAGATGACACCAGAAGAAAAATACCTAACTCAGAGATCAAGGTTCGCAGATTGTCCATTCAAAATACCAAGATAGATGTGGATACCACTAGGATGGAACATATGAGATCTCTTACCATTTTCACAAGTGATGTTGTTGGGAAAGTGTTGGATATTTCAAGTTTTCAAGTTCTGCGCGTGTTGGATTTAGAAGGTTGTAAAAATGTCTCAGATGTTGGGTATGTCGGGAATCTGTTACATTTGAGGTACTTGGGGCTAAAAGATACTCATGTTAAGGACCTTCCCATGGAAATAGGGAAGCTGCAGTTTTTGCTTACCTTGGACTTAAGAGGTTCTAATATAAAAGTACTGCCATCGAGTGTTGTTCAACTAAGACGTCTAATGTGCCTGTATGTTGATTATGATATGAAGCTGTCATCTGGGATAGGTAACCTGACATCCCTAGAAGTGCTAGATGACCTGGGGTTATCTGACGTGGACCTTGATTTTGTGAAAGAATTGGGCCGTCTGACCAAGCTCAGGGTGCTCCGGCTTGACTGCGATGATTTTGATGAGAGCCTGGGTAAAGCTTTGGAGGAATCCATTTGTAATATACACAAACTGGACAGTCTAGATGTATATGTCTCTGATGGACTCATCAATTGCCTGAGCGAAGATTGGGTGCCTCCTCCACAACTCCGTAGATTGGCTTTCCCGGCAATTCAAAGTTGGTTCGAGACATTGCCGTCATGGATTAATCCTTCATCCCTTCCTCTCCTCTCCTATCTGGAGATAACGTTGTTTGAAGTGCGACCGGAGGTCATCCAATTTCTAGGGACTCTACCTGCTCTTGTTTATCTCGAGATACTGGATCATTCTGTGTTCCAAGAAGCGCATGAGGTGGAAGCGCCCGTCCTTTCCTCTAATGTTGCATTATTCCCATGTGCGACAGAGTGCCGCTTCTATGGTATTGGTGCCGTGCCATCTATGTTTCCACGAGGAGCTGCGCCGAGGCTTAAACAGCTTAGGTTCGCTTTACCAGCGAAGTGGGTCTCCCGTGAAAACATTGATTTGGGCATGAGGCACCTTCCTTCCCTCCAGCGAGTCACTGTTACAGTTTCCCAAGGAGAAGCTAACGATCAGGAGGTGGATGAAGCAAAGGCTGCTGTGAGGGCCGCGGTGGAAGACCACCCCAACCGTCCCGTCCTCGAGATTTAA
Protein Sequence
  • >TraesCS3D02G474300.1
    MEIAMGAIGPLLPKLAELLVGELTMEKQVRKGIVSLVTELKLMHVVLSKVSKVPADQLDEGVKIWAGNVKELSYQMEDIVDAFMVRVGNDGESTNPRNRVKKILKKVKRLFKNGKDLHRISDALDEVVLQAKQLAELRQRYEQEMRDTSAHTSVDPRMMALYTDVTELVGIEETRDKLINMLIEDDDWSKYPLKTISIVGFGGLGKTTLAKAAYDKIKVQFDCGAFVSVSQNPEMKKVLKDILYGLDKVKYENIHNAARDEKYLIEDIIEFLNEKRYLIVVDDIWNEKAWELIKCAFSKKSPGSRLITTTRNVSVSTACCSFEGDIYRMEPLSDDVSRRLFCKRVFSQEEGCPRELLQVSEEILKKCGGIPLAIITIASLLANKGQIKAKDEWYALLSSIGHGLTEDRSLEQMKKILLFSYYDLPSYLKPCLLYLSIFPEDHAIVRGRLIWRWISEGLVYSDKQETSLYELGNSYFTELVNRSMVQPIGIDVEGNVEGCRVHDMVLDLICSLSSEENFVTILDDTRRKIPNSEIKVRRLSIQNTKIDVDTTRMEHMRSLTIFTSDVVGKVLDISSFQVLRVLDLEGCKNVSDVGYVGNLLHLRYLGLKDTHVKDLPMEIGKLQFLLTLDLRGSNIKVLPSSVVQLRRLMCLYVDYDMKLSSGIGNLTSLEVLDDLGLSDVDLDFVKELGRLTKLRVLRLDCDDFDESLGKALEESICNIHKLDSLDVYVSDGLINCLSEDWVPPPQLRRLAFPAIQSWFETLPSWINPSSLPLLSYLEITLFEVRPEVIQFLGTLPALVYLEILDHSVFQEAHEVEAPVLSSNVALFPCATECRFYGIGAVPSMFPRGAAPRLKQLRFALPAKWVSRENIDLGMRHLPSLQRVTVTVSQGEANDQEVDEAKAAVRAAVEDHPNRPVLEI