Gene Details:

• Gene ID: TraesCS7D02G080300
• Gene Symbol: Lr34 Yr18 Sr57 Pm38 Ltn1
• Gene Name: leaf rust
• Genome: Chinese_Spring1.0
• Species: Triticum aestivum

Functional Descriptions:

• The wheat gene Lr34 has supported resistance to these pathogens for more than 50 years. Lr34 is now shared by wheat cultivars around the world.
• Alleles of Lr34 conferring resistance or susceptibility differ by three genetic polymorphisms.
• The wheat gene Lr34 is associated with resistance to two rust diseases of wheat, leaf rust, and stripe rust , as well as powdery mildew.
• Previous studies have localized the codominant gene Lr34 on the short arm of chromosome 7D between the two markers gwm1220 and SWM10. We further reduced the target interval in a map-based cloning approach based on three high-resolution populations.
• The wheat resistance gene Lr34 results in the constitutive induction of multiple defense pathways in transgenic barley.
• The wheat Lr34 multipathogen resistance gene confers resistance to anthracnose and rust in sorghum.
• The wheat Lr34 gene provides resistance against multiple fungal pathogens in barley.
• The durable wheat disease resistance gene Lr34 confers common rust and northern corn leaf blight resistance in maize.
• Lr67 and Lr34 rust resistance genes have much in common–they confer broad spectrum resistance to multiple pathogens in wheat.
• Interestingly, in one genetic background the transgenic Lr34-based resistance resulted in improved seedling resistance without cold treatment. These data indicate that functional variability in Lr34-based resistance can be created using a transgenic approach

Function-related keywords:

• leaf ,  resistance ,  map-based-cloning ,  powdery-mildew ,  rust-resistance ,  rust ,  mildew-resistance ,  mildew ,  powdery-mildew-resistance

Literature:

• A putative ABC transporter confers durable resistance to multiple fungal pathogens in wheat.   DOI:  10.1126/science.1166453 ;  PMID:  19229000
• The wheat resistance gene Lr34 results in the constitutive induction of multiple defense pathways in transgenic barley.   DOI:  10.1111/tpj.13001 ;  PMID:  26315512
• The wheat Lr34 multipathogen resistance gene confers resistance to anthracnose and rust in sorghum.   DOI:  10.1111/pbi.12723 ;  PMID:  28301718
• The durable wheat disease resistance gene Lr34 confers common rust and northern corn leaf blight resistance in maize.   DOI:  10.1111/pbi.12647 ;  PMID:  27734576
• Lr67 and Lr34rust resistance genes have much in common – they confer broad spectrum resistance to multiple pathogens in wheat.   DOI:  10.1186/1471-2229-13-96 ;  PMID:  23819608
• Functional variability of the Lr34 durable resistance gene in transgenic wheat.   DOI:  10.1111/j.1467-7652.2012.00683.x ;  PMID:  22321563

Related News:

Gene Resources:

• NCBI ID: FJ436983.1
• UniProt accessions: C0JSA8

Sequences: