Gene Details:

• Gene ID: TraesCS2B02G182800
• Gene Symbol: Lr13 LrZH22
• Gene Name: LrLC10
• Genome: Chinese_Spring1.0
• Species: Triticum aestivum

Functional Descriptions:

• These results indicated that LrZH22/Lr13 is a high-temperature leaf rust resistance gene likely influenced by genetic background.
• Wheat leaf rust resistance gene Lr13 is a specific Ne2 allele for hybrid necrosis.
• In summary, we isolated the high-temperature leaf rust resistance gene LrZH22/Lr13 from the elite wheat cultivar Zhoumai 22 using map-based cloning, MutRenSeq, EMS mutagenesis, transgenic validation, and haplotype analysis.
• Independent cloning and genetic analysis revealed that els1/Ne2 is the same as LrZH22/Lr13. LrZH22/Lr13/els1/Ne2 encodes a NLR protein that triggers programmed cell death and exhibits pleiotropic effects on leaf rust resistance and hybrid necrosis.
• Yr27(TraesKAR2B01G0121530LC) is allelic to the leaf rust resistance gene Lr13, the Yr27 and Lr13 proteins show 97% sequence identity.

Function-related keywords:

• leaf ,  temperature ,  resistance ,  map-based-cloning ,  cell-death ,  programmed-cell-death ,  rust-resistance ,  rust

Literature:

• Fine Mapping of the Wheat Leaf Rust Resistance Gene LrLC10 (Lr13) and Validation of Its Co-segregation Markers.   DOI:  10.3389/fpls.2020.00470 ;  PMID:  32477377
• High-temperature wheat leaf rust resistance gene Lr13 exhibits pleiotropic effects on hybrid necrosis.   DOI:  10.1016/j.molp.2021.05.009 ;  PMID:  33965635
• Long-read genome sequencing of bread wheat facilitates disease resistance gene cloning.   DOI:  10.1038/s41588-022-01022-1 ;  PMID:  35288708

Related News:

• Frontiers in Plant Science | 北京市作物杂种优势与利用重点实验室解超杰团队精细定位小麦抗锈基因

Gene Resources:

• NCBI ID: 123044110
• UniProt accessions: A0A3B6C240

Sequences: